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SG11201404608WA - Mesenchymal stem cells conditioned medium and methods of generating and using the same - Google Patents

Mesenchymal stem cells conditioned medium and methods of generating and using the same

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Publication number
SG11201404608WA
SG11201404608WA SG11201404608WA SG11201404608WA SG11201404608WA SG 11201404608W A SG11201404608W A SG 11201404608WA SG 11201404608W A SG11201404608W A SG 11201404608WA SG 11201404608W A SG11201404608W A SG 11201404608WA SG 11201404608W A SG11201404608W A SG 11201404608WA
Authority
SG
Singapore
Prior art keywords
generating
methods
same
stem cells
mesenchymal stem
Prior art date
Application number
SG11201404608WA
Inventor
Tony Peled
Yair Steinhardt
Original Assignee
Gamida Cell Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gamida Cell Ltd filed Critical Gamida Cell Ltd
Publication of SG11201404608WA publication Critical patent/SG11201404608WA/en

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/00Drugs for skeletal disorders
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
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    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1352Mesenchymal stem cells
    • C12N2502/1358Bone marrow mesenchymal stem cells (BM-MSC)
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1352Mesenchymal stem cells
    • C12N2502/1382Adipose-derived stem cells [ADSC], adipose stromal stem cells

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  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Hospice & Palliative Care (AREA)
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SG11201404608WA 2012-02-13 2013-02-13 Mesenchymal stem cells conditioned medium and methods of generating and using the same SG11201404608WA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261597909P 2012-02-13 2012-02-13
US201261597899P 2012-02-13 2012-02-13
PCT/IL2013/050137 WO2013121427A1 (en) 2012-02-13 2013-02-13 Mesenchymal stem cells conditioned medium and methods of generating and using the same

Publications (1)

Publication Number Publication Date
SG11201404608WA true SG11201404608WA (en) 2014-09-26

Family

ID=47953447

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201404608WA SG11201404608WA (en) 2012-02-13 2013-02-13 Mesenchymal stem cells conditioned medium and methods of generating and using the same

Country Status (12)

Country Link
US (2) US20150064273A1 (en)
EP (2) EP2814951B1 (en)
JP (2) JP6348848B2 (en)
CN (2) CN104204192A (en)
AU (1) AU2013219945B2 (en)
BR (1) BR112014020119A2 (en)
CA (1) CA2863795A1 (en)
HK (1) HK1202581A1 (en)
IL (1) IL234095B (en)
IN (1) IN2014MN01680A (en)
SG (1) SG11201404608WA (en)
WO (2) WO2013121427A1 (en)

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