SG10202005892SA - Determining antigen recognition through barcoding of mhc multimers - Google Patents
Determining antigen recognition through barcoding of mhc multimersInfo
- Publication number
- SG10202005892SA SG10202005892SA SG10202005892SA SG10202005892SA SG10202005892SA SG 10202005892S A SG10202005892S A SG 10202005892SA SG 10202005892S A SG10202005892S A SG 10202005892SA SG 10202005892S A SG10202005892S A SG 10202005892SA SG 10202005892S A SG10202005892S A SG 10202005892SA
- Authority
- SG
- Singapore
- Prior art keywords
- barcoding
- antigen recognition
- mhc multimers
- determining antigen
- determining
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70539—MHC-molecules, e.g. HLA-molecules
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Virology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201470340 | 2014-06-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202005892SA true SG10202005892SA (en) | 2020-07-29 |
Family
ID=59272565
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202005892SA SG10202005892SA (en) | 2014-06-06 | 2015-06-08 | Determining antigen recognition through barcoding of mhc multimers |
| SG11201610177UA SG11201610177UA (en) | 2014-06-06 | 2015-06-08 | Determining antigen recognition through barcoding of mhc multimers |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201610177UA SG11201610177UA (en) | 2014-06-06 | 2015-06-08 | Determining antigen recognition through barcoding of mhc multimers |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20170343545A1 (en) |
| EP (3) | EP3628684B1 (en) |
| JP (4) | JP6956632B2 (en) |
| AU (3) | AU2015271324B2 (en) |
| CA (2) | CA2951325C (en) |
| DK (1) | DK3152232T3 (en) |
| ES (1) | ES2770634T3 (en) |
| PT (1) | PT3152232T (en) |
| SG (2) | SG10202005892SA (en) |
| WO (1) | WO2015185067A1 (en) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2794522C (en) | 2010-04-05 | 2019-11-26 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| US11435358B2 (en) | 2011-06-23 | 2022-09-06 | Board Of Regents, The University Of Texas System | Single molecule peptide sequencing |
| GB2577626B (en) | 2011-06-23 | 2020-09-23 | Univ Texas | Identifying peptides at the single molecule level |
| WO2016069124A1 (en) | 2014-09-15 | 2016-05-06 | Board Of Regents, The University Of Texas System | Improved single molecule peptide sequencing |
| US10323279B2 (en) | 2012-08-14 | 2019-06-18 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| CA2881685C (en) | 2012-08-14 | 2023-12-05 | 10X Genomics, Inc. | Microcapsule compositions and methods |
| US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10584381B2 (en) | 2012-08-14 | 2020-03-10 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10273541B2 (en) | 2012-08-14 | 2019-04-30 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9701998B2 (en) | 2012-12-14 | 2017-07-11 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10533221B2 (en) | 2012-12-14 | 2020-01-14 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| EP2931919B1 (en) | 2012-12-14 | 2019-02-20 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| JP2016511243A (en) | 2013-02-08 | 2016-04-14 | テンエックス・ジェノミクス・インコーポレイテッド | Polynucleotide barcode generation |
| US9868979B2 (en) | 2013-06-25 | 2018-01-16 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
| CA2943624A1 (en) | 2014-04-10 | 2015-10-15 | 10X Genomics, Inc. | Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same |
| SG10202005892SA (en) | 2014-06-06 | 2020-07-29 | Herlev Hospital | Determining antigen recognition through barcoding of mhc multimers |
| WO2015188839A2 (en) | 2014-06-13 | 2015-12-17 | Immudex Aps | General detection and isolation of specific cells by binding of labeled molecules |
| US12312640B2 (en) | 2014-06-26 | 2025-05-27 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| EP3161162A4 (en) | 2014-06-26 | 2018-01-10 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| WO2015200893A2 (en) | 2014-06-26 | 2015-12-30 | 10X Genomics, Inc. | Methods of analyzing nucleic acids from individual cells or cell populations |
| EP3244992B1 (en) | 2015-01-12 | 2023-03-08 | 10X Genomics, Inc. | Processes for barcoding nucleic acids |
| EP3262407B1 (en) | 2015-02-24 | 2023-08-30 | 10X Genomics, Inc. | Partition processing methods and systems |
| WO2016162309A1 (en) | 2015-04-10 | 2016-10-13 | Spatial Transcriptomics Ab | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| US10539564B2 (en) | 2015-07-22 | 2020-01-21 | Roche Sequencing Solutions, Inc. | Identification of antigen epitopes and immune sequences recognizing the antigens |
| WO2017013170A1 (en) | 2015-07-22 | 2017-01-26 | F. Hoffmann-La Roche Ag | Identification of antigen epitopes and immune sequences recognizing the antigens |
| EP3933047A1 (en) * | 2015-09-24 | 2022-01-05 | AbVitro LLC | Affinity-oligonucleotide conjugates and uses thereof |
| EP3882357B1 (en) | 2015-12-04 | 2022-08-10 | 10X Genomics, Inc. | Methods and compositions for nucleic acid analysis |
| AU2017332495A1 (en) * | 2016-09-24 | 2019-04-11 | Abvitro Llc | Affinity-oligonucleotide conjugates and uses thereof |
| US10815525B2 (en) | 2016-12-22 | 2020-10-27 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10550429B2 (en) | 2016-12-22 | 2020-02-04 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10011872B1 (en) | 2016-12-22 | 2018-07-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| EP4310183B1 (en) | 2017-01-30 | 2025-07-09 | 10X Genomics, Inc. | Methods and systems for droplet-based single cell barcoding |
| US10844372B2 (en) | 2017-05-26 | 2020-11-24 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
| EP4230746A3 (en) | 2017-05-26 | 2023-11-01 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
| WO2019099751A1 (en) | 2017-11-15 | 2019-05-23 | 10X Genomics, Inc. | Functionalized gel beads |
| US10829815B2 (en) | 2017-11-17 | 2020-11-10 | 10X Genomics, Inc. | Methods and systems for associating physical and genetic properties of biological particles |
| CN112005115A (en) | 2018-02-12 | 2020-11-27 | 10X基因组学有限公司 | Methods to characterize multiple analytes from single cells or cell populations |
| CN112262218B (en) | 2018-04-06 | 2024-11-08 | 10X基因组学有限公司 | Systems and methods for quality control in single cell processing |
| WO2019199945A1 (en) * | 2018-04-10 | 2019-10-17 | Board Of Regents, The University Of Texas System | Dna-barcoded antigen multimers and methods of use thereof |
| MX2020010701A (en) * | 2018-04-11 | 2021-01-20 | Enterome S A | ANTIGENIC PEPTIDES FOR THE PREVENTION AND TREATMENT OF CANCER. |
| WO2019217758A1 (en) | 2018-05-10 | 2019-11-14 | 10X Genomics, Inc. | Methods and systems for molecular library generation |
| EP3807636B1 (en) * | 2018-06-15 | 2024-01-31 | F. Hoffmann-La Roche AG | A system for identification of antigens recognized by t cell receptors expressed on tumor infiltrating lymphocytes |
| JP2021531750A (en) | 2018-07-12 | 2021-11-25 | ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System | Molecular neighborhood detection by oligonucleotide |
| JP2021534394A (en) * | 2018-08-14 | 2021-12-09 | ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System | A single molecule that sequences peptides bound to major histocompatibility complex |
| EP3844308A1 (en) | 2018-08-28 | 2021-07-07 | 10X Genomics, Inc. | Resolving spatial arrays |
| CN113366117B (en) | 2018-08-28 | 2025-08-05 | 10X基因组学股份有限公司 | Methods for transposase-mediated spatial labeling and analysis of genomic DNA in biological samples |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| CN110687298A (en) * | 2018-09-06 | 2020-01-14 | 天津美瑞特医疗科技有限公司 | Novel method for preparing MHC antigen peptide multimer detection reagent by using Chitosan polysaccharide as skeleton |
| WO2020056173A1 (en) * | 2018-09-13 | 2020-03-19 | Pact Pharma, Inc. | Antigen specific tcr identification using single-cell sorting |
| KR20210063379A (en) * | 2018-09-24 | 2021-06-01 | 브리스톨-마이어스 스큅 컴퍼니 | Barcoded peptide-MHC complexes and uses thereof |
| WO2020107496A1 (en) * | 2018-12-01 | 2020-06-04 | 铭道创新(北京)医疗技术有限公司 | Flow cytometry testing method for lymphocyte in immune cell |
| CN113767177B (en) | 2018-12-10 | 2025-01-14 | 10X基因组学有限公司 | Generation of capture probes for spatial analysis |
| US12258373B2 (en) | 2018-12-17 | 2025-03-25 | Immudex Aps | Panel comprising Borrelia MHC multimers |
| US20220042008A1 (en) * | 2018-12-18 | 2022-02-10 | Mbl International Corp. | COMPOSITIONS OF STREPTAVIDIN-OLIGO CONJUGATES OF pMHC OCCUPANCY |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| EP3931354A1 (en) | 2019-02-28 | 2022-01-05 | 10X Genomics, Inc. | Profiling of biological analytes with spatially barcoded oligonucleotide arrays |
| CN114127309A (en) | 2019-03-15 | 2022-03-01 | 10X基因组学有限公司 | Method for single cell sequencing using spatial arrays |
| WO2020198071A1 (en) | 2019-03-22 | 2020-10-01 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| EP3976820A1 (en) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| GB201909509D0 (en) * | 2019-07-02 | 2019-08-14 | Immunocore Ltd | Peptide-MHC complexes |
| KR102406463B1 (en) * | 2019-09-03 | 2022-06-10 | 재단법인 오송첨단의료산업진흥재단 | High-Throughput Screening Method using Individual Barcoding System for Identifying Optimal Signal Peptides to Enhance the Productivity of Protein |
| EP4055185A1 (en) | 2019-11-08 | 2022-09-14 | 10X Genomics, Inc. | Spatially-tagged analyte capture agents for analyte multiplexing |
| EP4589016A3 (en) | 2019-11-13 | 2025-10-08 | 10x Genomics, Inc. | Generating capture probes for spatial analysis |
| CN115038794A (en) | 2019-12-23 | 2022-09-09 | 10X基因组学有限公司 | Compositions and methods for using fixed biological samples in partition-based assays |
| WO2021141138A1 (en) * | 2020-01-10 | 2021-07-15 | シンクサイト株式会社 | Novel cellular phenotype screening method |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11835462B2 (en) | 2020-02-11 | 2023-12-05 | 10X Genomics, Inc. | Methods and compositions for partitioning a biological sample |
| US12449419B1 (en) | 2020-02-12 | 2025-10-21 | 10X Genomics, Inc. | Methods for detecting binding of peptide-MHC monomers to T cells |
| US11926863B1 (en) | 2020-02-27 | 2024-03-12 | 10X Genomics, Inc. | Solid state single cell method for analyzing fixed biological cells |
| US20230287394A1 (en) * | 2020-03-31 | 2023-09-14 | Repertoire Immune Medicines, Inc. | Barcodable exchangeable peptide-mhc multimer libraries |
| EP4139922A1 (en) * | 2020-04-21 | 2023-03-01 | Regeneron Pharmaceuticals, Inc. | Methods and systems for analysis of receptor interaction |
| EP4414459B1 (en) | 2020-05-22 | 2025-09-03 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| US12265079B1 (en) | 2020-06-02 | 2025-04-01 | 10X Genomics, Inc. | Systems and methods for detecting analytes from captured single biological particles |
| WO2022109339A1 (en) | 2020-11-20 | 2022-05-27 | Becton, Dickinson And Company | Use of dextramer in single cell analysis |
| US20240271120A1 (en) * | 2021-01-28 | 2024-08-15 | Gigavax Aps | Pmhc multiplexers for detection of antigen-specific cells |
| EP4284811A2 (en) * | 2021-01-28 | 2023-12-06 | Fwd Holding Aps | Pmhc multiplexers by addition of mhc2 and rolling circle peptide multimer display |
| EP4212653A1 (en) * | 2022-01-18 | 2023-07-19 | Universität Potsdam | Molecular tagging using position-oriented nucleic acid encryption |
| EP4519674A1 (en) | 2022-05-06 | 2025-03-12 | 10X Genomics, Inc. | Analysis of antigen and antigen receptor interactions |
| WO2023225294A1 (en) * | 2022-05-20 | 2023-11-23 | 10X Genomics, Inc. | Improved major histocompatibility complex molecules |
| WO2024231535A1 (en) | 2023-05-11 | 2024-11-14 | Immudex Aps | Mhc class i molecules |
| WO2025109111A1 (en) | 2023-11-22 | 2025-05-30 | Immudex Aps | Immune cell activating multimers |
| WO2025125477A1 (en) | 2023-12-12 | 2025-06-19 | Immudex Aps | Mhc class i molecule matched negative control reagents |
| WO2025144972A1 (en) * | 2023-12-29 | 2025-07-03 | Illumina, Inc. | Materials and methods for preparation of a spatial transcriptomics library |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001158800A (en) * | 1999-12-03 | 2001-06-12 | Jsr Corp | Avidin particles |
| DE60118527D1 (en) * | 2000-01-24 | 2006-05-18 | Compound Therapeutics Inc | SENSITIVE AND MULTIPLEXED DIAGNOSTIC TESTS FOR PROTEIN ANALYSIS |
| WO2005003394A2 (en) * | 2003-06-27 | 2005-01-13 | Nanosphere, Inc. | Bio-barcode based detection of target analytes |
| WO2009003492A1 (en) * | 2007-07-03 | 2009-01-08 | Dako Denmark A/S | Mhc multimers, methods for their generation, labeling and use |
| US7902121B2 (en) | 2001-07-02 | 2011-03-08 | The Board Of Trustees Of The Leland Stanford Junior University | MHC-antigen arrays for detection and characterization of immune responses |
| WO2003031591A2 (en) | 2001-10-10 | 2003-04-17 | Superarray Bioscience Corporation | Detecting targets by unique identifier nucleotide tags |
| GB2422834B8 (en) * | 2005-02-04 | 2007-01-04 | Proimmune Ltd | MHC oligomer and method of making the same |
| WO2009077173A2 (en) | 2007-12-19 | 2009-06-25 | Philochem Ag | Dna-encoded chemical libraries |
| AU2009234162A1 (en) * | 2008-04-09 | 2009-10-15 | California Institute Of Technology | Capture agents and related methods and systems for detecting and/or sorting targets |
| WO2010037397A1 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cmv immune monitoring |
| EP2337795A2 (en) * | 2008-10-01 | 2011-06-29 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
| KR101561325B1 (en) | 2008-11-03 | 2015-10-16 | 스티흐팅 산퀸 불드포르지닝 | Detecting antigen responsive cells in a sample |
| US8735327B2 (en) * | 2010-01-07 | 2014-05-27 | Jeansee, Llc | Combinatorial DNA taggants and methods of preparation and use thereof |
| WO2012044999A2 (en) * | 2010-10-01 | 2012-04-05 | Ludwig Institute For Cancer Research Ltd. | Reversible protein multimers, methods for their production and use |
| WO2013137737A1 (en) * | 2012-03-16 | 2013-09-19 | Flexgen B.V. | Methods of creating and screening of dna encoded combinatorial libraries of chemical antibodies |
| SG10202005892SA (en) | 2014-06-06 | 2020-07-29 | Herlev Hospital | Determining antigen recognition through barcoding of mhc multimers |
| WO2015188839A2 (en) * | 2014-06-13 | 2015-12-17 | Immudex Aps | General detection and isolation of specific cells by binding of labeled molecules |
| US9789974B2 (en) | 2015-10-19 | 2017-10-17 | Goodrich Corporation | Brake monitoring system |
-
2015
- 2015-06-08 SG SG10202005892SA patent/SG10202005892SA/en unknown
- 2015-06-08 DK DK15739508.8T patent/DK3152232T3/en active
- 2015-06-08 ES ES15739508T patent/ES2770634T3/en active Active
- 2015-06-08 EP EP19208285.7A patent/EP3628684B1/en active Active
- 2015-06-08 WO PCT/DK2015/050150 patent/WO2015185067A1/en not_active Ceased
- 2015-06-08 CA CA2951325A patent/CA2951325C/en active Active
- 2015-06-08 US US15/316,584 patent/US20170343545A1/en active Pending
- 2015-06-08 AU AU2015271324A patent/AU2015271324B2/en active Active
- 2015-06-08 PT PT157395088T patent/PT3152232T/en unknown
- 2015-06-08 JP JP2017516031A patent/JP6956632B2/en active Active
- 2015-06-08 EP EP15739508.8A patent/EP3152232B1/en not_active Revoked
- 2015-06-08 CA CA3205428A patent/CA3205428A1/en active Pending
- 2015-06-08 EP EP24200560.1A patent/EP4484450A3/en active Pending
- 2015-06-08 SG SG11201610177UA patent/SG11201610177UA/en unknown
-
2019
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| JP2025128229A (en) | 2025-09-02 |
| AU2015271324A1 (en) | 2017-01-12 |
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| EP4484450A3 (en) | 2025-03-26 |
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| PT3152232T (en) | 2020-02-19 |
| DK3152232T3 (en) | 2020-02-24 |
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