SG10201913726PA - Novel polypeptide and method of producing imp using the same - Google Patents
Novel polypeptide and method of producing imp using the sameInfo
- Publication number
- SG10201913726PA SG10201913726PA SG10201913726PA SG10201913726PA SG10201913726PA SG 10201913726P A SG10201913726P A SG 10201913726PA SG 10201913726P A SG10201913726P A SG 10201913726PA SG 10201913726P A SG10201913726P A SG 10201913726PA SG 10201913726P A SG10201913726P A SG 10201913726PA
- Authority
- SG
- Singapore
- Prior art keywords
- same
- novel polypeptide
- producing imp
- imp
- producing
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/15—Corynebacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020170173505A KR101916611B1 (en) | 2017-12-15 | 2017-12-15 | Novel polypeptide and method of producing IMP using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201913726PA true SG10201913726PA (en) | 2020-03-30 |
Family
ID=64362865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201913726PA SG10201913726PA (en) | 2017-12-15 | 2018-12-14 | Novel polypeptide and method of producing imp using the same |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11299521B2 (en) |
| EP (1) | EP3674312A4 (en) |
| JP (2) | JP6839763B2 (en) |
| KR (1) | KR101916611B1 (en) |
| CN (3) | CN109929016A (en) |
| AU (1) | AU2018378010B2 (en) |
| BR (2) | BR122021012602B1 (en) |
| CA (2) | CA3071038C (en) |
| MX (2) | MX374699B (en) |
| MY (1) | MY191029A (en) |
| RU (1) | RU2725193C1 (en) |
| SG (1) | SG10201913726PA (en) |
| WO (2) | WO2019117399A1 (en) |
| ZA (1) | ZA201903356B (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101916611B1 (en) * | 2017-12-15 | 2018-11-07 | 씨제이제일제당 (주) | Novel polypeptide and method of producing IMP using the same |
| KR101956510B1 (en) * | 2018-07-27 | 2019-03-08 | 씨제이제일제당 (주) | Novel inosine-5'-monophosphate dehydrogenase and method for producing 5'-inosine monophosphate using the same |
| KR102254632B1 (en) * | 2021-01-15 | 2021-05-21 | 씨제이제일제당 주식회사 | Novel Phytoene desaturase variant and a method for producing IMP using the same |
| KR102254633B1 (en) * | 2021-01-15 | 2021-05-21 | 씨제이제일제당 주식회사 | Novel 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase variant and a method for producing IMP using the same |
| KR102270701B1 (en) * | 2021-01-15 | 2021-06-29 | 씨제이제일제당 주식회사 | Novel D-alanine--D-alanine ligase variant and a method for producing IMP using the same |
| KR102288395B1 (en) * | 2021-01-15 | 2021-08-10 | 씨제이제일제당 주식회사 | Novel 1,4-alpha-glucan-branching enzyme variant and a method for producing IMP using the same |
| KR102254631B1 (en) * | 2021-01-15 | 2021-05-21 | 씨제이제일제당 주식회사 | Novel Peptide methionine sulfoxide reductase variant and a method for producing IMP using the same |
| KR102288396B1 (en) * | 2021-01-18 | 2021-08-10 | 씨제이제일제당 주식회사 | Novel anaerobic coproporphyrinogen Ⅲ oxidase variant and a method for producing IMP using the same |
| KR102303747B1 (en) * | 2021-04-12 | 2021-09-16 | 씨제이제일제당 (주) | Novel major facilitator superfamily permease variant and a method for producing L-lysine using the same |
| KR102277409B1 (en) * | 2021-04-29 | 2021-07-14 | 씨제이제일제당 주식회사 | Novel bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase variant and a method for producing IMP using the same |
| KR102277408B1 (en) * | 2021-04-29 | 2021-07-14 | 씨제이제일제당 주식회사 | Novel formate-dependent phosphoribosylglycinamide formyltransferase variant and a method for producing IMP using the same |
| KR102277410B1 (en) * | 2021-04-29 | 2021-07-14 | 씨제이제일제당 주식회사 | Novel bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase variant and a method for producing IMP using the same |
| WO2022231037A1 (en) * | 2021-04-29 | 2022-11-03 | 씨제이제일제당 (주) | Novel variant, and method for producing imp using same |
| KR20240150617A (en) * | 2023-04-06 | 2024-10-16 | 대상 주식회사 | Novel variant of threonine ammonia-lyase and method for producing 5'-inosinic acid using the same |
| KR102684450B1 (en) * | 2023-04-06 | 2024-07-15 | 대상 주식회사 | Novel variant of ABC transporter permease and method for producing 5'-inosinic acid using the same |
| KR102614734B1 (en) * | 2023-04-06 | 2023-12-19 | 대상 주식회사 | Novel variant of 5-dehydro-2-deooxygluconokinase and method for producing 5'-inosinic acid using the same |
| KR20240150616A (en) * | 2023-04-06 | 2024-10-16 | 대상 주식회사 | Novel variant of nucleotide hydrolase and method for producing 5'-inosinic acid using the same |
| KR102864071B1 (en) * | 2023-04-11 | 2025-09-25 | 대상 주식회사 | Novel variant of (p)ppGpp synthetase and method for producing 5'-inosinic acid using the same |
| KR20240151932A (en) * | 2023-04-11 | 2024-10-21 | 대상 주식회사 | Novel variant of pyruvate dehydrogenase and method for producing 5'-inosinic acid using the same |
| KR20240151933A (en) * | 2023-04-11 | 2024-10-21 | 대상 주식회사 | Novel variant of aldehyde dehydrogenase and method for producing 5'-inosinic acid using the same |
| KR102684451B1 (en) | 2023-04-11 | 2024-07-15 | 대상 주식회사 | Novel variant of PTS transporter subunit EIIC and method for producing 5'-inosinic acid using the same |
| KR102864072B1 (en) * | 2023-04-11 | 2025-09-25 | 대상 주식회사 | Novel variant of phosphotransferase and method for producing 5'-inosinic acid using the same |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0669386B2 (en) * | 1987-03-18 | 1994-09-07 | 協和醗酵工業株式会社 | Process for producing 5'-inosinic acid |
| GB8818560D0 (en) | 1988-08-04 | 1988-09-07 | Ici Plc | Novel compounds |
| WO1999055668A1 (en) | 1998-04-27 | 1999-11-04 | Kumiai Chemical Industry Co., Ltd. | 3-arylphenyl sulfide derivatives and insecticides and miticides |
| TWI222464B (en) * | 1999-02-08 | 2004-10-21 | Kyowa Hakko Kogyo Kk | Process for producing purine nucleotides |
| KR100446113B1 (en) | 2001-11-26 | 2004-08-30 | 씨제이 주식회사 | Microorganism producing 5-inosinic acid and process for producing 5-inosinic acid using the same |
| RU2260040C2 (en) * | 2002-02-11 | 2005-09-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Method for production of inosibe and inosine-5'-monophosphate, bacterium strain of genus bacillus as inosine producer (variants) |
| KR20070060207A (en) * | 2005-12-08 | 2007-06-13 | 씨제이 주식회사 | 5'-inosinic acid microorganism having high productivity of increased lipoamide dehydrogenase gene expression and a method of producing 5'-inosine acid using the same |
| KR20070060208A (en) * | 2005-12-08 | 2007-06-13 | 씨제이 주식회사 | Corynebacterium microorganisms having excellent 5'-inosine acid productivity with increased fumarase gene expression and a method for producing 5'-inosine acid using the same |
| CN101573438B (en) | 2006-09-15 | 2013-01-02 | Cj第一制糖株式会社 | A corynebacteria having enhanced L-lysine productivity and a method of producing L-lysine using the same |
| KR20080033001A (en) | 2006-10-12 | 2008-04-16 | 삼성전자주식회사 | Backlight unit and liquid crystal display having the same |
| KR100882418B1 (en) * | 2007-01-15 | 2009-02-05 | 씨제이제일제당 (주) | Microorganisms that produce inosine and methods for producing inosine using the same |
| KR100954052B1 (en) * | 2007-12-26 | 2010-04-20 | 씨제이제일제당 (주) | A microorganism of the genus Corynebacterium in which the gene encoding the ABC-transporter is inactivated and a method of preparing 5'-inosinic acid using the same |
| KR100959662B1 (en) * | 2008-01-04 | 2010-05-26 | 씨제이제일제당 (주) | Corynebacterium microorganisms having inosine production ability and production method of inosine using the same |
| CN102341376A (en) | 2009-03-04 | 2012-02-01 | 巴斯夫欧洲公司 | 3-arylquinazolin-4-one compounds for controlling invertebrate pests |
| WO2010108542A1 (en) * | 2009-03-25 | 2010-09-30 | Nestec S.A. | A natural taste enhancing savoury base and a process for its preparation |
| KR101166027B1 (en) | 2009-04-01 | 2012-07-19 | 씨제이제일제당 (주) | Microorganism belonging to the genus Corynebacterium having enhaced 5'-inosinic acid productivity and method for producing 5'-inosinic acid using the same |
| WO2013191113A1 (en) | 2012-06-18 | 2013-12-27 | 住友化学株式会社 | Fused heterocyclic compound |
| EP3019481B1 (en) | 2013-07-08 | 2019-03-06 | Bayer CropScience Aktiengesellschaft | Six-membered c-n linked arylsulfide and arylsulfoxide derivatives as pesticides |
| TW201609667A (en) | 2013-12-16 | 2016-03-16 | 拜耳作物科學股份有限公司 | Six-membered C-N-bonded aryl sulphide and aryl sulphoxide derivatives as pesticides |
| CN103773783B (en) * | 2014-01-23 | 2015-09-02 | 天津科技大学 | Recombinant expressed ribose phosphate transferring enzyme is utilized to produce the method for 5'-inosinic acid |
| US9924719B2 (en) | 2014-10-03 | 2018-03-27 | Sumitomo Chemical Company, Limited | Pyridazine compound |
| JP6540708B2 (en) | 2014-10-03 | 2019-07-10 | 住友化学株式会社 | Pyrimidinone compounds |
| KR101744958B1 (en) | 2014-12-24 | 2017-06-12 | 대상 주식회사 | Mutant Corynebacterium ammoniagenes Strain with Enhanced 5’-inosinic acid Production and Method for Preparing of 5’-inosinic acid Using the Same |
| KR101904675B1 (en) * | 2017-12-15 | 2018-10-04 | 씨제이제일제당 (주) | IMP-producing microorganism and method of producing IMP using the same |
| KR101916611B1 (en) * | 2017-12-15 | 2018-11-07 | 씨제이제일제당 (주) | Novel polypeptide and method of producing IMP using the same |
| KR101916622B1 (en) * | 2018-01-04 | 2018-11-07 | 씨제이제일제당 (주) | Novel polypeptide and method of producing IMP using the same |
-
2017
- 2017-12-15 KR KR1020170173505A patent/KR101916611B1/en active Active
-
2018
- 2018-02-22 WO PCT/KR2018/002208 patent/WO2019117399A1/en not_active Ceased
- 2018-03-08 CN CN201810192655.1A patent/CN109929016A/en active Pending
- 2018-12-14 BR BR122021012602-0A patent/BR122021012602B1/en active IP Right Grant
- 2018-12-14 CA CA3071038A patent/CA3071038C/en active Active
- 2018-12-14 MY MYPI2019003014A patent/MY191029A/en unknown
- 2018-12-14 CA CA3048392A patent/CA3048392C/en active Active
- 2018-12-14 BR BR112019011994-9A patent/BR112019011994B1/en active IP Right Grant
- 2018-12-14 JP JP2019535337A patent/JP6839763B2/en active Active
- 2018-12-14 US US16/346,041 patent/US11299521B2/en active Active
- 2018-12-14 CN CN201910462568.8A patent/CN110343150B/en active Active
- 2018-12-14 CN CN201880003810.9A patent/CN110248955B/en active Active
- 2018-12-14 WO PCT/KR2018/015937 patent/WO2019117673A2/en not_active Ceased
- 2018-12-14 RU RU2019113226A patent/RU2725193C1/en active
- 2018-12-14 SG SG10201913726PA patent/SG10201913726PA/en unknown
- 2018-12-14 EP EP18887344.2A patent/EP3674312A4/en active Pending
- 2018-12-14 MX MX2019006804A patent/MX374699B/en active IP Right Grant
- 2018-12-14 AU AU2018378010A patent/AU2018378010B2/en active Active
-
2019
- 2019-05-27 ZA ZA2019/03356A patent/ZA201903356B/en unknown
- 2019-06-11 MX MX2020001903A patent/MX2020001903A/en unknown
-
2020
- 2020-11-09 JP JP2020186549A patent/JP2021019645A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018378010B2 (en) | 2019-10-03 |
| MX374699B (en) | 2025-03-06 |
| JP2020505004A (en) | 2020-02-20 |
| MY191029A (en) | 2022-05-29 |
| BR112019011994B1 (en) | 2022-04-19 |
| WO2019117673A2 (en) | 2019-06-20 |
| BR122021012602B1 (en) | 2022-04-19 |
| CN110248955A (en) | 2019-09-17 |
| CA3071038C (en) | 2022-06-21 |
| ZA201903356B (en) | 2020-02-26 |
| EP3674312A4 (en) | 2020-10-21 |
| CN110343150B (en) | 2020-09-04 |
| MX2020001903A (en) | 2020-03-24 |
| RU2725193C1 (en) | 2020-06-30 |
| US11299521B2 (en) | 2022-04-12 |
| EP3674312A2 (en) | 2020-07-01 |
| CA3048392C (en) | 2020-09-22 |
| WO2019117673A3 (en) | 2019-08-01 |
| AU2018378010A1 (en) | 2019-07-04 |
| US20200377557A1 (en) | 2020-12-03 |
| CA3048392A1 (en) | 2019-06-20 |
| MX2019006804A (en) | 2019-08-01 |
| CN110248955B (en) | 2020-08-25 |
| WO2019117399A1 (en) | 2019-06-20 |
| CA3071038A1 (en) | 2019-06-20 |
| CN110343150A (en) | 2019-10-18 |
| JP6839763B2 (en) | 2021-03-10 |
| BR112019011994A2 (en) | 2019-11-12 |
| KR101916611B1 (en) | 2018-11-07 |
| CN109929016A (en) | 2019-06-25 |
| JP2021019645A (en) | 2021-02-18 |
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