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SG10201913697UA - Factor viii chimeric proteins and uses thereof - Google Patents

Factor viii chimeric proteins and uses thereof

Info

Publication number
SG10201913697UA
SG10201913697UA SG10201913697UA SG10201913697UA SG10201913697UA SG 10201913697U A SG10201913697U A SG 10201913697UA SG 10201913697U A SG10201913697U A SG 10201913697UA SG 10201913697U A SG10201913697U A SG 10201913697UA SG 10201913697U A SG10201913697U A SG 10201913697UA
Authority
SG
Singapore
Prior art keywords
factor viii
chimeric proteins
viii chimeric
proteins
factor
Prior art date
Application number
SG10201913697UA
Inventor
Ekta Seth Chhabra
Tongyao Liu
Original Assignee
Bioverativ Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53524349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201913697U(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bioverativ Therapeutics Inc filed Critical Bioverativ Therapeutics Inc
Publication of SG10201913697UA publication Critical patent/SG10201913697UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG10201913697UA 2014-01-10 2015-01-09 Factor viii chimeric proteins and uses thereof SG10201913697UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461926226P 2014-01-10 2014-01-10
US201461988104P 2014-05-02 2014-05-02

Publications (1)

Publication Number Publication Date
SG10201913697UA true SG10201913697UA (en) 2020-03-30

Family

ID=53524349

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201913697UA SG10201913697UA (en) 2014-01-10 2015-01-09 Factor viii chimeric proteins and uses thereof
SG10201805924PA SG10201805924PA (en) 2014-01-10 2015-01-09 Factor viii chimeric proteins and uses thereof
SG11201605242YA SG11201605242YA (en) 2014-01-10 2015-01-09 Factor viii chimeric proteins and uses thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG10201805924PA SG10201805924PA (en) 2014-01-10 2015-01-09 Factor viii chimeric proteins and uses thereof
SG11201605242YA SG11201605242YA (en) 2014-01-10 2015-01-09 Factor viii chimeric proteins and uses thereof

Country Status (29)

Country Link
US (3) US11192936B2 (en)
EP (3) EP4176894B1 (en)
JP (5) JP6749836B2 (en)
KR (1) KR102409250B1 (en)
CN (6) CN114736305B (en)
AU (3) AU2015204646B2 (en)
BR (1) BR112016015512B1 (en)
DK (2) DK3091997T5 (en)
EA (1) EA201691111A1 (en)
ES (2) ES2927475T3 (en)
FI (2) FI4176894T3 (en)
FR (1) FR24C1052I1 (en)
HR (2) HRP20240640T1 (en)
HU (3) HUE066567T2 (en)
IL (2) IL246476B (en)
LT (3) LT4176894T (en)
MX (2) MX389878B (en)
MY (2) MY192481A (en)
NL (1) NL301303I2 (en)
NO (1) NO2024057I1 (en)
NZ (1) NZ721544A (en)
PH (1) PH12016501323B1 (en)
PL (2) PL3091997T3 (en)
PT (2) PT4176894T (en)
RS (2) RS65533B1 (en)
SG (3) SG10201913697UA (en)
SI (2) SI4176894T1 (en)
UA (1) UA120917C2 (en)
WO (1) WO2015106052A1 (en)

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RS59876B1 (en) * 2012-07-11 2020-03-31 Bioverativ Therapeutics Inc Factor viii complex with xten and von willebrand factor protein, and uses thereof
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