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SG10201912576PA - Natural killer cells and ilc3 cells and uses thereof - Google Patents

Natural killer cells and ilc3 cells and uses thereof

Info

Publication number
SG10201912576PA
SG10201912576PA SG10201912576PA SG10201912576PA SG10201912576PA SG 10201912576P A SG10201912576P A SG 10201912576PA SG 10201912576P A SG10201912576P A SG 10201912576PA SG 10201912576P A SG10201912576P A SG 10201912576PA SG 10201912576P A SG10201912576P A SG 10201912576PA
Authority
SG
Singapore
Prior art keywords
cells
natural killer
ilc3
killer cells
ilc3 cells
Prior art date
Application number
SG10201912576PA
Inventor
Xiaokui Zhang
Ivana Djuretic
Lin Kang
Vanessa Voskinarian-Berse
Bhavani Stout
Robert J Hariri
Wolfgang Hofgartner
James Edinger
Eric Law
Vladimir Jankovic
Original Assignee
Celularity Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celularity Inc filed Critical Celularity Inc
Publication of SG10201912576PA publication Critical patent/SG10201912576PA/en

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
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SG10201912576PA 2015-10-15 2016-10-14 Natural killer cells and ilc3 cells and uses thereof SG10201912576PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562242246P 2015-10-15 2015-10-15
US201562272984P 2015-12-30 2015-12-30
US201662403571P 2016-10-03 2016-10-03

Publications (1)

Publication Number Publication Date
SG10201912576PA true SG10201912576PA (en) 2020-02-27

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Family Applications (2)

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SG10201912576PA SG10201912576PA (en) 2015-10-15 2016-10-14 Natural killer cells and ilc3 cells and uses thereof
SG11201803117YA SG11201803117YA (en) 2015-10-15 2016-10-14 Natural killer cells and ilc3 cells and uses thereof

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Country Status (17)

Country Link
US (2) US20180346877A1 (en)
EP (1) EP3362075B1 (en)
JP (3) JP2018535666A (en)
KR (1) KR20180059555A (en)
CN (1) CN109310710A (en)
AU (1) AU2016340005B2 (en)
BR (1) BR112018007538A2 (en)
CA (1) CA3002066A1 (en)
CO (1) CO2018004937A2 (en)
EA (1) EA201890960A1 (en)
IL (1) IL258666B2 (en)
MX (1) MX2018004600A (en)
MY (1) MY201637A (en)
NZ (1) NZ741612A (en)
SG (2) SG10201912576PA (en)
TW (1) TW201732037A (en)
WO (1) WO2017066530A1 (en)

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EP4076466A4 (en) * 2019-12-18 2023-07-12 Universite De Montreal CULLIN ADAPTER 3 KBTBD4 MODULATORS AS ANTICANCER COMPOUNDS
WO2021155312A1 (en) * 2020-01-29 2021-08-05 Celularity Inc. Placental derived natural killer cells for treatment of coronavirus infections
US12195759B2 (en) * 2020-02-21 2025-01-14 FullHope Biomedical Co., Ltd. Modified natural killer cells, pharmaceutical composition, manufacturing method thereof, and method of using the same
JP2021136883A (en) * 2020-03-02 2021-09-16 株式会社ガイアバイオメディシン Method for treating highly active nk cells
KR20220048775A (en) * 2020-10-13 2022-04-20 주식회사 노보셀바이오 Composition for anti-virus comprising natural killer cell
CN112285083B (en) * 2020-10-28 2022-01-07 上海睿钰生物科技有限公司 Method for evaluating cell killing efficacy
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TW202237826A (en) 2020-11-30 2022-10-01 瑞士商克里斯珀醫療股份公司 Gene-edited natural killer cells
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JPWO2023038037A1 (en) * 2021-09-08 2023-03-16
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NZ747910A (en) * 2016-05-07 2023-02-24 Celularity Inc Methods of treating acute myeloid leukemia and multiple myeloma using natural killer cells

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