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SG10201810760SA - Dna methylation status as a biomarker of alcohol use and abstinence - Google Patents

Dna methylation status as a biomarker of alcohol use and abstinence

Info

Publication number
SG10201810760SA
SG10201810760SA SG10201810760SA SG10201810760SA SG10201810760SA SG 10201810760S A SG10201810760S A SG 10201810760SA SG 10201810760S A SG10201810760S A SG 10201810760SA SG 10201810760S A SG10201810760S A SG 10201810760SA SG 10201810760S A SG10201810760S A SG 10201810760SA
Authority
SG
Singapore
Prior art keywords
abstinence
biomarker
dna methylation
methylation status
alcohol use
Prior art date
Application number
SG10201810760SA
Inventor
Robert Philibert
Original Assignee
Robert Philibert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Philibert filed Critical Robert Philibert
Publication of SG10201810760SA publication Critical patent/SG10201810760SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00—Reactions characterised by treatment of reaction samples
    • C12Q2523/10—Characterised by chemical treatment
    • C12Q2523/125—Bisulfite(s)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

DNA METHYLATION STATUS AS A BIOMARKER OF ALCOHOL USE AND ABSTINENCE This disclosure provides methods and materials for determining whether or not an individual is using alcohol, and also for determining whether or not the individual has stopped using alcohol. Figure 1
SG10201810760SA 2014-05-30 2015-05-28 Dna methylation status as a biomarker of alcohol use and abstinence SG10201810760SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462005408P 2014-05-30 2014-05-30

Publications (1)

Publication Number Publication Date
SG10201810760SA true SG10201810760SA (en) 2018-12-28

Family

ID=54699995

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201608817TA SG11201608817TA (en) 2014-05-30 2015-05-28 Dna methylation status as a biomarker of alcohol use and abstinence
SG10201810760SA SG10201810760SA (en) 2014-05-30 2015-05-28 Dna methylation status as a biomarker of alcohol use and abstinence

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201608817TA SG11201608817TA (en) 2014-05-30 2015-05-28 Dna methylation status as a biomarker of alcohol use and abstinence

Country Status (14)

Country Link
US (1) US20170306405A1 (en)
EP (1) EP3149206B1 (en)
JP (1) JP6807833B2 (en)
KR (1) KR20170013921A (en)
CN (1) CN106661618B (en)
AU (1) AU2015265431B2 (en)
BR (1) BR112016028127A2 (en)
CA (1) CA2947128A1 (en)
ES (1) ES2827241T3 (en)
IL (1) IL248602A0 (en)
MX (1) MX2016015759A (en)
NO (1) NO20161786A1 (en)
SG (2) SG11201608817TA (en)
WO (1) WO2015181779A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201516972D0 (en) 2015-09-25 2015-11-11 Epiontis Gmbh LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells
US11817214B1 (en) 2019-09-23 2023-11-14 FOXO Labs Inc. Machine learning model trained to determine a biochemical state and/or medical condition using DNA epigenetic data
US11795495B1 (en) 2019-10-02 2023-10-24 FOXO Labs Inc. Machine learned epigenetic status estimator
CN120019147A (en) * 2023-09-14 2025-05-16 石药集团中奇制药技术（石家庄）有限公司 Antisense oligonucleotide for inhibiting TRPV1 gene expression and its application

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010129354A2 (en) * 2009-04-28 2010-11-11 University Of Iowa Research Foundation Compositions and methods for detecting predisposition to a substance use disorder
GB201004147D0 (en) * 2010-03-12 2010-04-28 Dna Electronics Ltd Method and apparatus for sensing methylation
US20120149589A1 (en) * 2010-12-14 2012-06-14 Kent Hutchison Epigentic Markers Associated with Substance Use Disorders

Also Published As

Publication number Publication date
JP6807833B2 (en) 2021-01-06
WO2015181779A3 (en) 2016-03-10
ES2827241T3 (en) 2021-05-20
IL248602A0 (en) 2016-12-29
AU2015265431A1 (en) 2016-11-10
EP3149206A4 (en) 2017-11-15
EP3149206A2 (en) 2017-04-05
CN106661618A (en) 2017-05-10
US20170306405A1 (en) 2017-10-26
CN106661618B (en) 2021-06-08
WO2015181779A2 (en) 2015-12-03
EP3149206B1 (en) 2020-09-02
CA2947128A1 (en) 2015-12-03
SG11201608817TA (en) 2016-11-29
JP2017518077A (en) 2017-07-06
NO20161786A1 (en) 2016-11-11
KR20170013921A (en) 2017-02-07
BR112016028127A2 (en) 2017-08-22
AU2015265431B2 (en) 2021-04-01
MX2016015759A (en) 2017-06-06

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