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SG10201808811QA - Method and compositions for cellular immunotherapy - Google Patents

Method and compositions for cellular immunotherapy

Info

Publication number
SG10201808811QA
SG10201808811QA SG10201808811QA SG10201808811QA SG10201808811QA SG 10201808811Q A SG10201808811Q A SG 10201808811QA SG 10201808811Q A SG10201808811Q A SG 10201808811QA SG 10201808811Q A SG10201808811Q A SG 10201808811QA SG 10201808811Q A SG10201808811Q A SG 10201808811QA
Authority
SG
Singapore
Prior art keywords
polynucleotide
cells
compositions
cellular immunotherapy
alternatives
Prior art date
Application number
SG10201808811QA
Inventor
Michael C Jensen
Original Assignee
Seattle Childrens Hospital Dba Seattle Childrens Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54288361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201808811Q(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Seattle Childrens Hospital Dba Seattle Childrens Res Inst filed Critical Seattle Childrens Hospital Dba Seattle Childrens Res Inst
Publication of SG10201808811QA publication Critical patent/SG10201808811QA/en

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Abstract

METHOD AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY The present invention provides nucleic acids, vectors, host cells, methods and compositions to confer and/or augment immune responses mediated by cellular immunotherapy, such as by adoptively transferring CD+ central memory T cells or combinations of central memory T cells with CD4+ T cells that are genetically modified to express a chimeric receptor. In some alternatives the genetically modified host cell comprises a nucleic acid comprising a polynucleotide coding for a ligand binding domain, a polynucleotide comprising a customized spacer region, a polynucleotide comprising a transmembrane domain, and a polynucleotide comprising an intracellular signaling domain. In some alternatives, the ligand binding domains binds to CD171. FIG. 13A -142-
SG10201808811QA 2014-04-10 2015-04-08 Method and compositions for cellular immunotherapy SG10201808811QA (en)

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US201461977751P 2014-04-10 2014-04-10
US201461986479P 2014-04-30 2014-04-30
US201462058973P 2014-10-02 2014-10-02
US201462088363P 2014-12-05 2014-12-05
US201462089730P 2014-12-09 2014-12-09
US201462090845P 2014-12-11 2014-12-11

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SG10201808819XA SG10201808819XA (en) 2014-04-10 2015-04-08 Transgene genetic tags and methods of use
SG10201808833XA SG10201808833XA (en) 2014-04-10 2015-04-08 Drug regulated transgene expression
SG11201608396YA SG11201608396YA (en) 2014-04-10 2015-04-08 Drug related transgene expression
SG10201808825XA SG10201808825XA (en) 2014-04-10 2015-04-08 Defined composition gene modified t-cell products
SG11201608392WA SG11201608392WA (en) 2014-04-10 2015-04-08 Method and compositions for cellular immunotherapy
SG11201608395PA SG11201608395PA (en) 2014-04-10 2015-04-08 Defined composition gene modified t-cell products
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SG11201608396YA SG11201608396YA (en) 2014-04-10 2015-04-08 Drug related transgene expression
SG10201808825XA SG10201808825XA (en) 2014-04-10 2015-04-08 Defined composition gene modified t-cell products
SG11201608392WA SG11201608392WA (en) 2014-04-10 2015-04-08 Method and compositions for cellular immunotherapy
SG11201608395PA SG11201608395PA (en) 2014-04-10 2015-04-08 Defined composition gene modified t-cell products
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