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SG10201805749QA - Substantially animal protein-free recombinant furin and methods for producing same - Google Patents

Substantially animal protein-free recombinant furin and methods for producing same

Info

Publication number
SG10201805749QA
SG10201805749QA SG10201805749QA SG10201805749QA SG10201805749QA SG 10201805749Q A SG10201805749Q A SG 10201805749QA SG 10201805749Q A SG10201805749Q A SG 10201805749QA SG 10201805749Q A SG10201805749Q A SG 10201805749QA SG 10201805749Q A SG10201805749Q A SG 10201805749QA
Authority
SG
Singapore
Prior art keywords
methods
animal protein
producing same
recombinant furin
substantially animal
Prior art date
Application number
SG10201805749QA
Inventor
Barbara Plaimauer
Fircks Simone Von
Leopold Grillberger
Meinhard Hasslacher
Roland Geyer
Artur Mitterer
Manfred Reiter
Original Assignee
Baxalta Inc
Baxalta GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40524590&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201805749Q(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxalta Inc, Baxalta GmbH filed Critical Baxalta Inc
Publication of SG10201805749QA publication Critical patent/SG10201805749QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6454—Dibasic site splicing serine proteases, e.g. kexin (3.4.21.61); furin (3.4.21.75) and other proprotein convertases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SUBSTANTIALLYANIMAL PROTEIN-FREE RECOMBINANT FURIN AND METHODS FOR PRODUCING SAME The present application relates to recombinant furin (rFurin) and methods for producing rFurin. More specifically, the invention relates to substantially animal protein-free rFurin and methods for producing substantially animal protein-free rFurin. No suitable figure
SG10201805749QA 2007-12-31 2008-12-19 Substantially animal protein-free recombinant furin and methods for producing same SG10201805749QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1815207P 2007-12-31 2007-12-31

Publications (1)

Publication Number Publication Date
SG10201805749QA true SG10201805749QA (en) 2018-08-30

Family

ID=40524590

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201805749QA SG10201805749QA (en) 2007-12-31 2008-12-19 Substantially animal protein-free recombinant furin and methods for producing same
SG2013051693A SG192471A1 (en) 2007-12-31 2008-12-19 Substantially animal protein-free recombinant furin and methods for producing same

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2013051693A SG192471A1 (en) 2007-12-31 2008-12-19 Substantially animal protein-free recombinant furin and methods for producing same

Country Status (18)

Country Link
US (2) US20090181423A1 (en)
EP (2) EP2240578B1 (en)
JP (2) JP5806465B2 (en)
KR (1) KR101618144B1 (en)
CN (2) CN101910401A (en)
AR (2) AR069892A1 (en)
AU (1) AU2008346817B2 (en)
BR (1) BRPI0821467B8 (en)
CA (1) CA2710260C (en)
DK (1) DK2240578T3 (en)
ES (2) ES2735173T3 (en)
HU (1) HUE043863T2 (en)
MX (1) MX2010007344A (en)
NZ (1) NZ586411A (en)
PL (2) PL3521422T3 (en)
PT (1) PT2240578T (en)
SG (2) SG10201805749QA (en)
WO (1) WO2009088713A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008141824A2 (en) * 2007-05-22 2008-11-27 Baxter International Inc. Preparative purification process for human furin
MX2010007344A (en) 2007-12-31 2010-11-09 Baxter Int Substantially animal protein-free recombinant furin and methods for producing same.
US8241623B1 (en) 2009-02-09 2012-08-14 David Bermudes Protease sensitivity expression system
CN103097522A (en) 2010-07-08 2013-05-08 巴克斯特国际公司 Method for producing recombinant ADAMTS13 in cell culture
WO2012122611A1 (en) * 2011-03-11 2012-09-20 Universidade De São Paulo - Usp Method for the production of recombinant human factor viii
SG10201604488TA (en) * 2011-06-02 2016-07-28 Baxter Int Formulations Of Recombinant Furin
AR102048A1 (en) * 2014-08-12 2017-02-01 Baxalta Inc FACTOR X PRODUCTION COMPLETELY PROCESSED AND FUNCTIONAL IN A FURINA SECRETION MAMMAL EXPRESSION SYSTEM
IL253071B2 (en) * 2014-12-22 2024-04-01 Genzyme Corp Methods of culturing a mammalian cell
CN111183151B (en) * 2017-06-23 2024-06-07 武田药品工业株式会社 Purification of Factor VIII subspecies

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1815207A (en) 1929-01-18 1931-07-21 John H Moffat Vehicle parking and locking device
NL9000917A (en) 1989-10-25 1991-05-16 Holland Biotechnology PHARMACEUTICAL PREPARATION WITH ENDOPROTEOLYTIC ACTIVITY; PROCESS FOR ENDOPROTEOLYTIC PROCESSING OF (PRECURSOR) PROTEINS AND FOR (MICRO) ORGANIC PREPARATION OF PROTEINS.
JP4236698B2 (en) * 1990-11-26 2009-03-11 ジェネティックス インスティチュート，リミテッド ライアビリティ カンパニー Expression of PACE in host cells and uses thereof
US5604201A (en) * 1993-01-08 1997-02-18 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization Methods and reagents for inhibiting furin endoprotease
AT404838B (en) * 1995-11-24 1999-03-25 Immuno Ag PRODUCTION OF PROTEINS FROM PRO-PROTEINS BY FUSION PROTEINS DERIVED FROM FURIN OR FURINANALOGS
US6103529A (en) 1996-10-10 2000-08-15 Life Technologies, Inc. Animal cell culture media comprising peptides derived from rice
AT407750B (en) 1999-02-19 2001-05-25 Immuno Ag METHOD FOR PRODUCING A VWF PREPARATION
US6596526B1 (en) * 2000-06-09 2003-07-22 Baxter Aktiengesellschaft Furin polypeptides with improved characteristics
SE0103084D0 (en) * 2001-09-14 2001-09-14 Amersham Pharm Biotech Ab Generation of ion exchange media
US20030091976A1 (en) * 2001-11-14 2003-05-15 Ciphergen Biosystems, Inc. Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry
JP2005532057A (en) * 2002-07-09 2005-10-27 バクスター・インターナショナル・インコーポレイテッド Animal protein-free medium for culturing cells
CA2552639C (en) * 2004-02-27 2012-05-01 Ge Healthcare Bio-Sciences Ab A process for the purification of antibodies
KR101423344B1 (en) * 2006-01-04 2014-07-30 백스터 인터내셔널 인코포레이티드 Methods for expressing proteins using oligopeptide-free cell culture medium
WO2008141824A2 (en) 2007-05-22 2008-11-27 Baxter International Inc. Preparative purification process for human furin
MX2010007344A (en) 2007-12-31 2010-11-09 Baxter Int Substantially animal protein-free recombinant furin and methods for producing same.
WO2013070520A2 (en) 2011-11-03 2013-05-16 Barson Composites Corporation Corrosion-resistant diffusion coatings

Also Published As

Publication number Publication date
EP2240578A1 (en) 2010-10-20
CA2710260C (en) 2023-07-11
HUE043863T2 (en) 2019-09-30
PL3521422T3 (en) 2021-12-20
US20090181423A1 (en) 2009-07-16
EP3521422B1 (en) 2021-10-06
AU2008346817B2 (en) 2014-07-24
JP2015154790A (en) 2015-08-27
AU2008346817A1 (en) 2009-07-16
EP3521422A1 (en) 2019-08-07
WO2009088713A1 (en) 2009-07-16
CN101910401A (en) 2010-12-08
AR069892A1 (en) 2010-02-24
BRPI0821467A2 (en) 2014-10-14
KR101618144B1 (en) 2016-05-17
PT2240578T (en) 2019-06-19
JP5806465B2 (en) 2015-11-10
SG192471A1 (en) 2013-08-30
PL2240578T3 (en) 2019-09-30
KR20100114057A (en) 2010-10-22
US20110076719A1 (en) 2011-03-31
AR113492A2 (en) 2020-05-06
EP2240578B1 (en) 2019-03-20
CN110066782A (en) 2019-07-30
BRPI0821467B1 (en) 2019-10-15
ES2735173T3 (en) 2019-12-16
CA2710260A1 (en) 2009-07-16
NZ586411A (en) 2012-06-29
US9127264B2 (en) 2015-09-08
ES2897561T3 (en) 2022-03-01
BRPI0821467B8 (en) 2021-05-25
MX2010007344A (en) 2010-11-09
CN110066782B (en) 2024-04-16
JP2011507550A (en) 2011-03-10
DK2240578T3 (en) 2019-06-17

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