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SG10201803541TA - Biologically active c-terminal arginine-containing peptides - Google Patents

Biologically active c-terminal arginine-containing peptides

Info

Publication number
SG10201803541TA
SG10201803541TA SG10201803541TA SG10201803541TA SG10201803541TA SG 10201803541T A SG10201803541T A SG 10201803541TA SG 10201803541T A SG10201803541T A SG 10201803541TA SG 10201803541T A SG10201803541T A SG 10201803541TA SG 10201803541T A SG10201803541T A SG 10201803541TA
Authority
SG
Singapore
Prior art keywords
containing peptides
biologically active
terminal arginine
arginine
terminal
Prior art date
Application number
SG10201803541TA
Inventor
James Wilkins
Masaru Shiratori
Tim Breece
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG10201803541TA publication Critical patent/SG10201803541TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

BIOLOGICALLYACTIVE C-TERMINAL ARGININE-CONTAINING PEPTIDES The present invention concerns the separation, identification and characterization of active peptide fragments from peptones. Figure: 23
SG10201803541TA 2007-09-05 2008-09-05 Biologically active c-terminal arginine-containing peptides SG10201803541TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96764407P 2007-09-05 2007-09-05

Publications (1)

Publication Number Publication Date
SG10201803541TA true SG10201803541TA (en) 2018-06-28

Family

ID=40084302

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2013032669A SG190602A1 (en) 2007-09-05 2008-09-05 Biologically active c-terminal arginine-containing peptides
SG10201803541TA SG10201803541TA (en) 2007-09-05 2008-09-05 Biologically active c-terminal arginine-containing peptides

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2013032669A SG190602A1 (en) 2007-09-05 2008-09-05 Biologically active c-terminal arginine-containing peptides

Country Status (14)

Country Link
US (5) US20090143248A1 (en)
EP (1) EP2207790B1 (en)
JP (1) JP5734653B2 (en)
CN (2) CN101848925A (en)
CA (1) CA2697519C (en)
CY (1) CY1114618T1 (en)
DK (1) DK2207790T3 (en)
ES (1) ES2434829T3 (en)
HR (1) HRP20131108T1 (en)
PL (1) PL2207790T3 (en)
PT (1) PT2207790E (en)
SG (2) SG190602A1 (en)
SI (1) SI2207790T1 (en)
WO (1) WO2009033024A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009033024A1 (en) * 2007-09-05 2009-03-12 Genentech, Inc. Biologically active c-terminal arginine-containing peptides
DE102010001983A1 (en) * 2010-02-16 2011-08-18 peptides&elephants GmbH, 14558 A process for producing a graphite-based peptide purification material and process for peptide purification
JP2013536683A (en) * 2010-08-31 2013-09-26 フリエスランド ブランズ ビー．ブイ． Culture medium for eukaryotic cells
CN107312759B (en) * 2012-09-19 2025-10-28 珍白斯凯尔有限公司 Cell penetrating peptide, conjugate comprising the peptide, and composition comprising the conjugate
WO2017178193A1 (en) * 2016-04-14 2017-10-19 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Method for the identification of random polynucleotide or polypeptide sequences with biological activity
CN109575106A (en) * 2019-01-07 2019-04-05 无限极（中国）有限公司 A kind of method and application preparing anti-oxidant tripeptides from big mpd polypeptide
KR20230124607A (en) * 2020-12-22 2023-08-25 가부시키가이샤 마루하치 무라마쓰 Peptide, cell growth promoter, protein production promoter, medium, cell proliferation method using the peptide, and protein production method using the peptide
CN116444610B (en) * 2022-11-30 2024-05-17 内蒙古伊利实业集团股份有限公司 Milk active peptide DASAQFIR and preparation method and application thereof

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USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
WO1987002701A1 (en) * 1985-10-22 1987-05-07 Plant Genetics, Inc. Methods and media for enhanced somatic embryogenesis
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
IL87737A (en) 1987-09-11 1993-08-18 Genentech Inc Method for culturing polypeptide factor dependent vertebrate recombinant cells
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US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
HU226219B1 (en) * 1996-05-31 2008-06-30 Intervet Int Bv Live attenuated rtx-producing bacteria of the family pasteurellaceae
EP0810283A3 (en) 1996-05-31 1997-12-10 Akzo Nobel N.V. Live attenuated RTX-procucing bacteria of the family Pasteurellaceae
US20020045266A1 (en) * 2000-02-08 2002-04-18 Hicham Fenniri Method for determining the structure of an active member of a chemical library
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WO2004035608A2 (en) * 2002-10-18 2004-04-29 Abgenix, Inc. System and method for cleaving antibodies
WO2009033024A1 (en) * 2007-09-05 2009-03-12 Genentech, Inc. Biologically active c-terminal arginine-containing peptides
EP2490021A1 (en) * 2011-02-18 2012-08-22 Biotempt B.V. Modulators of PRR and GPCR signalling

Also Published As

Publication number Publication date
US20090143248A1 (en) 2009-06-04
EP2207790A1 (en) 2010-07-21
CA2697519A1 (en) 2009-03-12
SI2207790T1 (en) 2013-11-29
CN101848925A (en) 2010-09-29
EP2207790B1 (en) 2013-08-21
ES2434829T3 (en) 2013-12-17
JP2010538089A (en) 2010-12-09
PT2207790E (en) 2013-11-04
US20210163880A1 (en) 2021-06-03
US20170088813A1 (en) 2017-03-30
CA2697519C (en) 2018-11-20
US20170321187A1 (en) 2017-11-09
SG190602A1 (en) 2013-06-28
CN104844690B (en) 2019-08-16
CY1114618T1 (en) 2016-10-05
HRP20131108T1 (en) 2014-01-31
DK2207790T3 (en) 2013-10-28
US20110183413A1 (en) 2011-07-28
PL2207790T3 (en) 2014-01-31
HK1213916A1 (en) 2016-07-15
CN104844690A (en) 2015-08-19
JP5734653B2 (en) 2015-06-17
WO2009033024A1 (en) 2009-03-12

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