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SG10201801371PA - Microparticles for cell disruption and/or biomolecule recovery - Google Patents

Microparticles for cell disruption and/or biomolecule recovery

Info

Publication number
SG10201801371PA
SG10201801371PA SG10201801371PA SG10201801371PA SG10201801371PA SG 10201801371P A SG10201801371P A SG 10201801371PA SG 10201801371P A SG10201801371P A SG 10201801371PA SG 10201801371P A SG10201801371P A SG 10201801371PA SG 10201801371P A SG10201801371P A SG 10201801371PA
Authority
SG
Singapore
Prior art keywords
microparticles
cell disruption
biomolecule recovery
biomolecule
recovery
Prior art date
Application number
SG10201801371PA
Inventor
Rainer Hahn
Alois Jungbauer
Alexandru Trefilov
Original Assignee
Boehringer Ingelheim Rcv Gmbh
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Rcv Gmbh, Sandoz Ag filed Critical Boehringer Ingelheim Rcv Gmbh
Publication of SG10201801371PA publication Critical patent/SG10201801371PA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/04Processes using organic exchangers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/362Cation-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/363Anion-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/04Processes using organic exchangers
    • B01J39/05Processes using organic exchangers in the strongly acidic form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/04Processes using organic exchangers
    • B01J39/07Processes using organic exchangers in the weakly acidic form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16Organic material
    • B01J39/18Macromolecular compounds
    • B01J39/20Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26Cation exchangers for chromatographic processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/04Processes using organic exchangers
    • B01J41/05Processes using organic exchangers in the strongly basic form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/04Processes using organic exchangers
    • B01J41/07Processes using organic exchangers in the weakly basic form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/08Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/12Macromolecular compounds
    • B01J41/14Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20Anion exchangers for chromatographic processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00Ion-exchange processes in general; Apparatus therefor
    • B01J47/02Column or bed processes
    • B01J47/04Mixed-bed processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0089Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y115/00Oxidoreductases acting on superoxide as acceptor (1.15)
    • C12Y115/01Oxidoreductases acting on superoxide as acceptor (1.15) with NAD or NADP as acceptor (1.15.1)
    • C12Y115/01001Superoxide dismutase (1.15.1.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG10201801371PA 2013-08-23 2014-08-25 Microparticles for cell disruption and/or biomolecule recovery SG10201801371PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13181537 2013-08-23
EP13181540 2013-08-23

Publications (1)

Publication Number Publication Date
SG10201801371PA true SG10201801371PA (en) 2018-04-27

Family

ID=51589254

Family Applications (3)

Application Number Title Priority Date Filing Date
SG11201600574XA SG11201600574XA (en) 2013-08-23 2014-08-25 Microparticles for cell disruption and/or biomolecule recovery
SG11201600275PA SG11201600275PA (en) 2013-08-23 2014-08-25 Novel adsorbent composition and use thereof
SG10201801371PA SG10201801371PA (en) 2013-08-23 2014-08-25 Microparticles for cell disruption and/or biomolecule recovery

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SG11201600574XA SG11201600574XA (en) 2013-08-23 2014-08-25 Microparticles for cell disruption and/or biomolecule recovery
SG11201600275PA SG11201600275PA (en) 2013-08-23 2014-08-25 Novel adsorbent composition and use thereof

Country Status (9)

Country Link
US (3) US10076749B2 (en)
EP (2) EP3036249B1 (en)
JP (3) JP2016531128A (en)
KR (2) KR20160065092A (en)
CN (3) CN105764914B (en)
AU (2) AU2014310479B2 (en)
CA (2) CA2919288A1 (en)
SG (3) SG11201600574XA (en)
WO (2) WO2015025063A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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CA2919288A1 (en) * 2013-08-23 2015-02-26 Boehringer Ingelheim Rcv Gmbh & Co Kg Microparticles for cell disruption and/or biomolecule recovery
US10626376B2 (en) * 2016-11-14 2020-04-21 St. Jude Children's Research Hospital Method for isolating and purifying adeno-associated virus particles using salt
EP4467565A3 (en) 2016-12-21 2025-03-12 Amgen Inc. Anti-tnf alpha antibody formulations
KR101964242B1 (en) * 2017-04-26 2019-04-01 한국과학기술원 System and Method for Assay Using Hybrid Structures
CN108342382B (en) * 2018-01-30 2020-12-15 广东海大畜牧兽医研究院有限公司 Method for quickly extracting nucleic acid and kit thereof
CN109402112A (en) * 2018-11-08 2019-03-01 华中农业大学 A method of quick, low cost separates pcr template from chicken blood
CN110221010B (en) * 2019-04-29 2021-12-14 贵州茅台酒股份有限公司 A kind of method for determination of pyrone compounds in Maotai-flavor liquor Daqu
JP7544339B2 (en) * 2020-09-03 2024-09-03 日機装株式会社 Method for regenerating liquid to be treated, regenerator for liquid to be treated, and regenerator for liquid to be treated
US20220194791A1 (en) * 2020-12-22 2022-06-23 Tokyo Ohka Kogyo Co., Ltd. Method for producing aqueous solution of purified orthoperiodic acid, method for producing semiconductor device, and aqueous solution of orthoperiodic acid
CN112979352A (en) * 2021-03-08 2021-06-18 亚太建设科技信息研究院有限公司 Method for recovering phosphate in urine
CN113337452A (en) * 2021-04-19 2021-09-03 中国医学科学院医学生物学研究所 Method for preparing double-factor antibody by serum-free culture expression of high-density CHO-S cells
CN117241881A (en) * 2021-06-10 2023-12-15 三菱化学株式会社 Synthetic adsorbent, antibody purification method and antibody manufacturing method
CN113607903B (en) * 2021-07-30 2024-03-15 振德医疗用品股份有限公司 Method for detecting bacterial endotoxin containing positive charge polymer
CN115245814B (en) * 2021-12-06 2023-08-11 青岛大学 A kind of adsorbent for fixed bed prepared from solid waste and its preparation method
CN115404235B (en) * 2022-09-16 2025-06-13 广东海天创新技术有限公司 Extraction method of total microbial DNA from soybean paste
WO2024132899A1 (en) * 2022-12-21 2024-06-27 Climeworks Ag Uses of amino sorbents for capturing of co2 from gas streams
CN116287077A (en) * 2023-03-13 2023-06-23 山东至善硒生物科技有限公司 Selenium polypeptide extraction method
CN118458887A (en) * 2024-05-09 2024-08-09 中国科学院水生生物研究所 A method for enhanced coagulation and algae removal in drinking water plant
CN120330138B (en) * 2025-06-20 2025-08-29 上海沐医医学生物工程有限公司 Culture medium additive of MSC and application thereof

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Also Published As

Publication number Publication date
EP3036249A1 (en) 2016-06-29
SG11201600275PA (en) 2016-02-26
WO2015025063A1 (en) 2015-02-26
SG11201600574XA (en) 2016-02-26
CA2919288A1 (en) 2015-02-26
AU2014310479B2 (en) 2020-01-30
US20190046969A1 (en) 2019-02-14
EP3036249B1 (en) 2019-03-13
CN105764914A (en) 2016-07-13
KR20160065093A (en) 2016-06-08
JP2016531128A (en) 2016-10-06
JP2020019799A (en) 2020-02-06
WO2015025062A1 (en) 2015-02-26
US10076749B2 (en) 2018-09-18
CN105683210B (en) 2020-07-14
US10537887B2 (en) 2020-01-21
AU2014310479A1 (en) 2016-02-25
US20160193598A1 (en) 2016-07-07
EP3036250A1 (en) 2016-06-29
JP2016530271A (en) 2016-09-29
AU2014310480A1 (en) 2016-02-25
AU2014310480B2 (en) 2020-03-05
KR20160065092A (en) 2016-06-08
US20160200760A1 (en) 2016-07-14
CA2921883A1 (en) 2015-02-26
CN105683210A (en) 2016-06-15
CA2921883C (en) 2020-03-24
CN105764914B (en) 2020-12-25
CN111875665A (en) 2020-11-03
US10661264B2 (en) 2020-05-26

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