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SG10201501513TA - Culture additives to boost stem cell proliferation and differentiation response - Google Patents

Culture additives to boost stem cell proliferation and differentiation response

Info

Publication number
SG10201501513TA
SG10201501513TA SG10201501513TA SG10201501513TA SG10201501513TA SG 10201501513T A SG10201501513T A SG 10201501513TA SG 10201501513T A SG10201501513T A SG 10201501513TA SG 10201501513T A SG10201501513T A SG 10201501513TA SG 10201501513T A SG10201501513T A SG 10201501513TA
Authority
SG
Singapore
Prior art keywords
stem cell
cell proliferation
culture additives
differentiation response
boost
Prior art date
Application number
SG10201501513TA
Other languages
English (en)
Inventor
Michael Raghunath
Hui Li Loe
Anna Blocki
Yanxian Peng
Original Assignee
Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Singapore filed Critical Univ Singapore
Publication of SG10201501513TA publication Critical patent/SG10201501513TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653Adipocytes; Adipose tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/90Polysaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG10201501513TA 2010-03-02 2011-03-02 Culture additives to boost stem cell proliferation and differentiation response SG10201501513TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30950910P 2010-03-02 2010-03-02

Publications (1)

Publication Number Publication Date
SG10201501513TA true SG10201501513TA (en) 2015-04-29

Family

ID=44542449

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201501513TA SG10201501513TA (en) 2010-03-02 2011-03-02 Culture additives to boost stem cell proliferation and differentiation response
SG2012061420A SG183400A1 (en) 2010-03-02 2011-03-02 Culture additives to boost stem cell proliferation and differentiation response

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2012061420A SG183400A1 (en) 2010-03-02 2011-03-02 Culture additives to boost stem cell proliferation and differentiation response

Country Status (5)

Country Link
US (1) US20120322152A1 (fr)
EP (1) EP2542666A4 (fr)
CA (1) CA2791846A1 (fr)
SG (2) SG10201501513TA (fr)
WO (1) WO2011108993A1 (fr)

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ES2400916T3 (es) 2005-06-08 2013-04-15 Janssen Biotech, Inc. Una terapia celular para degeneración ocular
US8741643B2 (en) 2006-04-28 2014-06-03 Lifescan, Inc. Differentiation of pluripotent stem cells to definitive endoderm lineage
US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
CA3207103A1 (fr) 2007-07-31 2009-02-05 Janssen Biotech, Inc. Differenciation de cellules souches embryonnaires humaines de l'endocrine pancreatique
ATE523585T1 (de) 2007-11-27 2011-09-15 Lifescan Inc Differenzierung menschlicher embryonaler stammzellen
RU2551772C2 (ru) 2008-02-21 2015-05-27 Сентокор Орто Байотек Инк. Способы, поверхностно-модифицированные носители и композиции для иммобилизации, культивирования и открепления клеток
BRPI0914116A2 (pt) 2008-06-30 2019-09-17 Centocor Ortho Biotech Inc diferenciação de células-tronco pluripotentes
CN107435038B (zh) 2008-10-31 2021-07-09 詹森生物科技公司 人胚胎干细胞向胰腺内分泌谱系的分化
RU2522001C2 (ru) 2008-10-31 2014-07-10 Сентокор Орто Байотек Инк. Дифференцирование человеческих эмбриональных стволовых клеток в линию панкреатических эндокринных клеток
CA2744227C (fr) 2008-11-20 2018-10-02 Centocor Ortho Biotech Inc. Procedes et compositions pour adhesion cellulaire et culture sur des substrats plans
JP2012509085A (ja) 2008-11-20 2012-04-19 ヤンセン バイオテツク,インコーポレーテツド マイクロキャリア上での多能性幹細胞の培養
EP2456858B1 (fr) 2009-07-20 2018-08-29 Janssen Biotech, Inc. Différenciation de cellules souches embryonnaires humaines
SG177481A1 (en) 2009-07-20 2012-02-28 Janssen Biotech Inc Differentiation of human embryonic stem cells
SG181685A1 (en) 2009-12-23 2012-07-30 Centocor Ortho Biotech Inc Differentiation of human embryonic stem cells
CA2784415C (fr) 2009-12-23 2019-06-18 Jean Xu Differenciation de cellules souches embryonnaires humaines
SG183535A1 (en) 2010-03-01 2012-10-30 Janssen Biotech Inc Methods for purifying cells derived from pluripotent stem cells
MX351515B (es) 2010-05-12 2017-10-17 Janssen Biotech Inc Diferenciacion de celulas madre embrionarias humanas.
AU2011296383B2 (en) 2010-08-31 2016-03-10 Janssen Biotech, Inc. Differentiation of pluripotent stem cells
ES2658146T3 (es) 2010-08-31 2018-03-08 Janssen Biotech, Inc. Diferenciación de células madre embrionarias humanas
CN103221536B (zh) 2010-08-31 2016-08-31 詹森生物科技公司 人胚胎干细胞的分化
SG10201601853XA (en) * 2011-03-11 2016-04-28 Univ Singapore Pericyte progenitors from peripheral blood
AU2012355698B2 (en) 2011-12-22 2018-11-29 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into single hormonal insulin positive cells
US9434920B2 (en) 2012-03-07 2016-09-06 Janssen Biotech, Inc. Defined media for expansion and maintenance of pluripotent stem cells
US20150030662A1 (en) * 2012-03-12 2015-01-29 National University Of Singapore Generation of Brown Adipose Tissue (BAT) from Mesenchymal Cells
KR20150003233A (ko) 2012-03-30 2015-01-08 아지노모토 가부시키가이샤 황산화 화합물을 포함하는 줄기 세포 증식용 배지
JP6450674B2 (ja) * 2012-05-07 2019-01-09 ヤンセン バイオテツク,インコーポレーテツド ヒト胚性幹細胞の膵臓の内胚葉への分化
MX358590B (es) 2012-06-08 2018-08-24 Janssen Biotech Inc Diferenciacion de celulas madre embrionarias humanas en celulas endocrinas pancreaticas.
US10344264B2 (en) 2012-12-31 2019-07-09 Janssen Biotech, Inc. Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
SG10201707811XA (en) 2012-12-31 2017-11-29 Janssen Biotech Inc Differentiation of human embryonic stem cells into pancreatic endocrine cells using hb9 regulators
AU2013370228B2 (en) 2012-12-31 2018-10-18 Janssen Biotech, Inc. Suspension and clustering of human pluripotent cells for differentiation into pancreatic endocrine cells
JP6071007B2 (ja) * 2013-08-22 2017-02-01 富士フイルム株式会社 観察画像撮影評価装置および方法並びにプログラム
JP5876453B2 (ja) * 2013-09-26 2016-03-02 株式会社Screenホールディングス 培養品質評価方法
EP3140394A4 (fr) * 2014-05-05 2017-12-27 National University of Singapore Procédés de production de constructions mimétiques de tissu et utilisations associées
SG10201810739VA (en) 2014-05-16 2019-01-30 Janssen Biotech Inc Use of small molecules to enhance mafa expression in pancreatic endocrine cells
MA45479A (fr) 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
US20220213441A1 (en) * 2019-05-16 2022-07-07 The Chinese University Of Hong Kong Extracellular matrix material and uses thereof
AU2021263179A1 (en) * 2020-04-30 2022-11-17 Oriental Yeast Co.,Ltd. Stem cell medium and stem cell culturing method

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DK1759536T3 (da) * 2004-06-01 2011-09-05 Kwalata Trading Ltd In vitro-teknikker til anvendelse med stamceller
WO2007149926A1 (fr) * 2006-06-20 2007-12-27 Wisconsin Alumni Research Foundation Procédé de culture de cellules souches
WO2010040699A1 (fr) * 2008-10-06 2010-04-15 Mc2 Cell Aps Système de bioréacteur à multiples cultures
JP5678360B2 (ja) * 2009-09-28 2015-03-04 株式会社ジーシー 間葉系幹細胞の培養方法

Also Published As

Publication number Publication date
EP2542666A4 (fr) 2014-05-07
US20120322152A1 (en) 2012-12-20
CA2791846A1 (fr) 2011-09-09
SG183400A1 (en) 2012-09-27
EP2542666A1 (fr) 2013-01-09
WO2011108993A1 (fr) 2011-09-09

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