SG10201500674YA - Pluripotent stem cells - Google Patents
Pluripotent stem cellsInfo
- Publication number
- SG10201500674YA SG10201500674YA SG10201500674YA SG10201500674YA SG10201500674YA SG 10201500674Y A SG10201500674Y A SG 10201500674YA SG 10201500674Y A SG10201500674Y A SG 10201500674YA SG 10201500674Y A SG10201500674Y A SG 10201500674YA SG 10201500674Y A SG10201500674Y A SG 10201500674YA
- Authority
- SG
- Singapore
- Prior art keywords
- stem cells
- pluripotent stem
- pluripotent
- cells
- stem
- Prior art date
Links
- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/117—Keratinocyte growth factors (KGF-1, i.e. FGF-7; KGF-2, i.e. FGF-12)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/605—Nanog
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/608—Lin28
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2510/00—Genetically modified cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25614909P | 2009-10-29 | 2009-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201500674YA true SG10201500674YA (en) | 2015-04-29 |
Family
ID=43925858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201500674YA SG10201500674YA (en) | 2009-10-29 | 2010-10-28 | Pluripotent stem cells |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20110104805A1 (en) |
| EP (1) | EP2494035B1 (en) |
| JP (2) | JP5957382B2 (en) |
| KR (1) | KR101861584B1 (en) |
| CN (2) | CN102695790A (en) |
| AR (1) | AR078805A1 (en) |
| AU (1) | AU2010319921A1 (en) |
| BR (1) | BR112012010136A2 (en) |
| CA (1) | CA2778817A1 (en) |
| ES (1) | ES2665006T3 (en) |
| MX (1) | MX350966B (en) |
| PH (1) | PH12012500818A1 (en) |
| PL (1) | PL2494035T3 (en) |
| RU (1) | RU2012122025A (en) |
| SG (1) | SG10201500674YA (en) |
| WO (1) | WO2011059725A2 (en) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| EP2610336A1 (en) | 2007-07-31 | 2013-07-03 | Lifescan, Inc. | Differentiation of human embryonic stem cells |
| MX2010009251A (en) | 2008-02-21 | 2010-11-25 | Centocor Ortho Biotech Inc | Methods, surface modified plates and compositions for cell attachment, cultivation and detachment. |
| ES2697798T3 (en) | 2008-06-30 | 2019-01-28 | Janssen Biotech Inc | Differentiation of pluripotent stem cells |
| JP2012509085A (en) | 2008-11-20 | 2012-04-19 | ヤンセン バイオテツク,インコーポレーテツド | Culture of pluripotent stem cells on microcarriers |
| CA2744227C (en) | 2008-11-20 | 2018-10-02 | Centocor Ortho Biotech Inc. | Methods and compositions for cell attachment and cultivation on planar substrates |
| EP2456862A4 (en) | 2009-07-20 | 2013-02-27 | Janssen Biotech Inc | Differentiation of human embryonic stem cells |
| DK2516625T3 (en) | 2009-12-23 | 2024-09-09 | Janssen Biotech Inc | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS |
| AU2011223900A1 (en) | 2010-03-01 | 2012-09-13 | Janssen Biotech, Inc. | Methods for purifying cells derived from pluripotent stem cells |
| SG187946A1 (en) | 2010-08-31 | 2013-03-28 | Janssen Biotech Inc | Differentiation of human embryonic stem cells |
| KR102090751B1 (en) | 2011-12-22 | 2020-03-19 | 얀센 바이오테크 인코포레이티드 | Differentiation of human embryonic stem cells into single hormonal insulin positive cells |
| US20150064141A1 (en) | 2012-04-05 | 2015-03-05 | The Regents Of The University Of California | Regenerative sera cells and mesenchymal stem cells |
| CN108034633B (en) | 2012-06-08 | 2022-08-02 | 詹森生物科技公司 | Differentiation of human embryonic stem cells into pancreatic endocrine cells |
| US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
| RU2018116647A (en) | 2012-12-31 | 2018-10-24 | Янссен Байотек, Инк. | CULTIVATION OF HUMAN EMBRYONAL STEM CELLS IN THE AIR-LIQUID INTERACTION PURPOSE FOR THEIR DIFFERENTIATION IN PANCREATIC ENDOCRINE CELLS |
| MX2015008578A (en) | 2012-12-31 | 2015-09-07 | Janssen Biotech Inc | Differentiation of human embryonic stem cells into pancreatic endocrine cells using hb9 regulators. |
| CN105705634A (en) | 2012-12-31 | 2016-06-22 | 詹森生物科技公司 | Suspension and clustering of human pluripotent cells for differentiation into pancreatic endocrine cells |
| KR102580225B1 (en) | 2013-06-11 | 2023-09-20 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | SC-β CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME |
| CN117821369A (en) | 2014-05-16 | 2024-04-05 | 詹森生物科技公司 | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells |
| CN113234661A (en) | 2014-12-18 | 2021-08-10 | 哈佛学院校长同事会 | Method for producing stem cell-derived beta cells and method for using same |
| WO2016100898A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof |
| WO2016100909A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | METHODS FOR GENERATING STEM CELL-DERIVED β CELLS AND USES THEREOF |
| EP3234109A4 (en) | 2014-12-19 | 2018-06-27 | Janssen Biotech, Inc. | Suspension culturing of pluripotent stem cells |
| AU2016228894B2 (en) | 2015-03-11 | 2021-03-04 | Ccs Ventures Limited | Pancreatic endocrine progenitor cell therapies for the treatment of obesity and Type 2 diabetes (T2D) |
| CN104988115A (en) * | 2015-07-14 | 2015-10-21 | 中国科学院过程工程研究所 | Application of quinoline or isoquinoline small-molecular compound in culture and cryopreservation of multipotential stem cells of human |
| MA45479A (en) | 2016-04-14 | 2019-02-20 | Janssen Biotech Inc | DIFFERENTIATION OF PLURIPOTENT STEM CELLS IN ENDODERMAL CELLS OF MIDDLE INTESTINE |
| MA45502A (en) | 2016-06-21 | 2019-04-24 | Janssen Biotech Inc | GENERATION OF FUNCTIONAL BETA CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS WITH GLUCOSE-DEPENDENT MITOCHONDRIAL RESPIRATION AND TWO-PHASE INSULIN SECRETION RESPONSE |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| AU2018370029B2 (en) | 2017-11-15 | 2024-11-07 | Vertex Pharmaceuticals Incorporated | Islet cell manufacturing compositions and methods of use |
| CA3108275A1 (en) | 2018-08-10 | 2020-02-13 | Vertex Pharmaceuticals Incorporated | Stem cell derived islet differentiation |
| CN110564674B (en) * | 2019-09-29 | 2021-05-11 | 广东工业大学 | A kind of stem cell bottoming working solution and its application |
| US20210309962A1 (en) * | 2020-04-01 | 2021-10-07 | Bruce K. Young | Compositions and methods utilizing amniotic fluid stem cells |
| AU2021296296A1 (en) * | 2020-06-22 | 2023-01-19 | Life Technologies Corporation | Methods and compositions for cultivating pluripotent cell suspensions |
| CN115418343A (en) * | 2022-10-28 | 2022-12-02 | 深圳市俊元生物科技有限公司 | Method for extracting pluripotent stem cells from human retinal pigment epithelial cells |
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- 2010-10-28 CA CA2778817A patent/CA2778817A1/en not_active Abandoned
- 2010-10-28 BR BR112012010136A patent/BR112012010136A2/en not_active Application Discontinuation
- 2010-10-28 AU AU2010319921A patent/AU2010319921A1/en not_active Abandoned
- 2010-10-28 JP JP2012537026A patent/JP5957382B2/en not_active Expired - Fee Related
- 2010-10-28 WO PCT/US2010/054408 patent/WO2011059725A2/en not_active Ceased
- 2010-10-28 EP EP10830437.9A patent/EP2494035B1/en not_active Not-in-force
- 2010-10-28 RU RU2012122025/10A patent/RU2012122025A/en not_active Application Discontinuation
- 2010-10-28 US US12/913,834 patent/US20110104805A1/en not_active Abandoned
- 2010-10-28 AR ARP100103962A patent/AR078805A1/en unknown
- 2010-10-28 ES ES10830437.9T patent/ES2665006T3/en active Active
- 2010-10-28 PH PH1/2012/500818A patent/PH12012500818A1/en unknown
- 2010-10-28 MX MX2012004999A patent/MX350966B/en active IP Right Grant
- 2010-10-28 SG SG10201500674YA patent/SG10201500674YA/en unknown
- 2010-10-28 KR KR1020127013705A patent/KR101861584B1/en not_active Expired - Fee Related
- 2010-10-28 PL PL10830437T patent/PL2494035T3/en unknown
- 2010-10-28 CN CN2010800497211A patent/CN102695790A/en active Pending
- 2010-10-28 CN CN201611048756.9A patent/CN107058389A/en active Pending
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2015
- 2015-12-28 JP JP2015256405A patent/JP6227622B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20110104805A1 (en) | 2011-05-05 |
| AU2010319921A1 (en) | 2012-05-17 |
| AR078805A1 (en) | 2011-12-07 |
| MX350966B (en) | 2017-09-26 |
| CN102695790A (en) | 2012-09-26 |
| RU2012122025A (en) | 2013-12-10 |
| JP5957382B2 (en) | 2016-07-27 |
| JP6227622B2 (en) | 2017-11-08 |
| JP2016127828A (en) | 2016-07-14 |
| PH12012500818A1 (en) | 2019-11-29 |
| PL2494035T3 (en) | 2018-07-31 |
| WO2011059725A2 (en) | 2011-05-19 |
| KR20120099241A (en) | 2012-09-07 |
| EP2494035A2 (en) | 2012-09-05 |
| KR101861584B1 (en) | 2018-05-28 |
| EP2494035B1 (en) | 2018-02-28 |
| BR112012010136A2 (en) | 2015-09-15 |
| ES2665006T3 (en) | 2018-04-24 |
| CN107058389A (en) | 2017-08-18 |
| CA2778817A1 (en) | 2011-05-19 |
| EP2494035A4 (en) | 2013-09-25 |
| JP2013509184A (en) | 2013-03-14 |
| WO2011059725A3 (en) | 2011-07-21 |
| MX2012004999A (en) | 2012-09-28 |
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