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SE9904108D0 - Nya föreningar - Google Patents

Nya föreningar

Info

Publication number
SE9904108D0
SE9904108D0 SE9904108A SE9904108A SE9904108D0 SE 9904108 D0 SE9904108 D0 SE 9904108D0 SE 9904108 A SE9904108 A SE 9904108A SE 9904108 A SE9904108 A SE 9904108A SE 9904108 D0 SE9904108 D0 SE 9904108D0
Authority
SE
Sweden
Prior art keywords
sub
new compounds
treatment
antibacterial
antiparasitic
Prior art date
Application number
SE9904108A
Other languages
English (en)
Swedish (sv)
Inventor
Sabrina Muzi
Shoa A Abdul-Rahman
Original Assignee
New Pharma Research Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New Pharma Research Ab filed Critical New Pharma Research Ab
Priority to SE9904108A priority Critical patent/SE9904108D0/xx
Publication of SE9904108D0 publication Critical patent/SE9904108D0/xx
Priority to AU17472/01A priority patent/AU1747201A/en
Priority to PCT/SE2000/002217 priority patent/WO2001036408A1/fr
Priority to US10/111,898 priority patent/US6967205B1/en
Priority to AT00980176T priority patent/ATE398117T1/de
Priority to JP2001538897A priority patent/JP2003514812A/ja
Priority to EP00980176A priority patent/EP1230235B1/fr
Priority to DE60039183T priority patent/DE60039183D1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SE9904108A 1999-11-15 1999-11-15 Nya föreningar SE9904108D0 (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE9904108A SE9904108D0 (sv) 1999-11-15 1999-11-15 Nya föreningar
AU17472/01A AU1747201A (en) 1999-11-15 2000-11-13 Compounds with antibacterial and antiparasitic properties
PCT/SE2000/002217 WO2001036408A1 (fr) 1999-11-15 2000-11-13 Composes antibacteriens et antiparasitaires
US10/111,898 US6967205B1 (en) 1999-11-15 2000-11-13 Compounds with antibacterial and antiparasitic properties
AT00980176T ATE398117T1 (de) 1999-11-15 2000-11-13 Verbindungen mit antibakteriellen und antiparasitischen eigenschaften
JP2001538897A JP2003514812A (ja) 1999-11-15 2000-11-13 抗菌性および抗寄生虫性を有する化合物
EP00980176A EP1230235B1 (fr) 1999-11-15 2000-11-13 Composes antibacteriens et antiparasitaires
DE60039183T DE60039183D1 (de) 1999-11-15 2000-11-13 Verbindungen mit antibakteriellen und antiparasitischen eigenschaften

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9904108A SE9904108D0 (sv) 1999-11-15 1999-11-15 Nya föreningar

Publications (1)

Publication Number Publication Date
SE9904108D0 true SE9904108D0 (sv) 1999-11-15

Family

ID=20417705

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9904108A SE9904108D0 (sv) 1999-11-15 1999-11-15 Nya föreningar

Country Status (8)

Country Link
US (1) US6967205B1 (fr)
EP (1) EP1230235B1 (fr)
JP (1) JP2003514812A (fr)
AT (1) ATE398117T1 (fr)
AU (1) AU1747201A (fr)
DE (1) DE60039183D1 (fr)
SE (1) SE9904108D0 (fr)
WO (1) WO2001036408A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8163769B2 (en) 2002-03-12 2012-04-24 Abbott Laboratories Antibacterial compounds
GB0215775D0 (en) * 2002-07-06 2002-08-14 Astex Technology Ltd Pharmaceutical compounds
AU2003266542A1 (en) * 2002-10-11 2004-05-04 Meiji Seika Kaisha, Ltd. Mixed compositions for controlling parasitic insects
MXPA05009688A (es) * 2003-03-12 2005-12-05 Abbott Lab Derivados de naftiridina como agentes antibacterianos.
DK1666477T3 (da) 2003-09-10 2013-07-29 Kyorin Seiyaku Kk 7-(4-trisubstitueret 3-cyclopropylaminomethyl-1- pyrrolidinyl)-quinoloncarboxylsyre-derivat
US20050124625A1 (en) * 2003-10-21 2005-06-09 Salvati Mark E. Piperazine derivatives and their use as modulators of nuclear hormone receptor function
US7498341B2 (en) * 2004-01-31 2009-03-03 Sanofi Aventis Deutschland Gmbh Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
WO2005097752A1 (fr) * 2004-03-31 2005-10-20 Bayer Pharmaceuticals Corporation Derives d'acide carboxylique de quinolone pour le traitement des troubles hyperproliferatifs
WO2007070506A2 (fr) 2005-12-14 2007-06-21 Amgen Inc. Derives diaza heterocycliques de sulfonamide et leurs utilisations
ES2427247T3 (es) * 2006-03-13 2013-10-30 Kyorin Pharmaceutical Co., Ltd. Aminoquinolonas como inhibidores de GSK-3
EP2149571A4 (fr) * 2007-05-24 2010-09-01 Kyorin Seiyaku Kk Dérivé de la mutiline ayant une structure d'acide carboxylique à noyau aromatique hétérocyclique en substituant à la position 14
US7902227B2 (en) 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
CN101855228B (zh) * 2007-09-11 2012-10-24 杏林制药株式会社 作为gsk-3抑制剂的氰基氨基喹诺酮和四唑并氨基喹诺酮
CN102344457B (zh) 2007-09-12 2015-07-22 杏林制药株式会社 作为 gsk-3 抑制剂的螺环状氨基喹诺酮
WO2009090548A2 (fr) * 2008-01-17 2009-07-23 Glenmark Pharmaceuticals, S.A. Dérivés de 3-azabicyclo[3.1.0]hexane utilisés comme ligands des récepteurs vanilloïdes
FR2928150A1 (fr) * 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
CN102421784B (zh) 2009-03-11 2015-09-30 杏林制药株式会社 作为gsk-3抑制剂的7-环烷基氨基喹诺酮
CN102030737B (zh) * 2010-10-29 2014-03-26 重庆巴仕迪动物药业有限公司 克林沙星氨基衍生物及其应用
WO2013142628A2 (fr) * 2012-03-20 2013-09-26 Fred Hutchinson Cancer Research Center Composés et compositions antibiotiques, et procédés d'identification associés
US8877931B2 (en) * 2012-08-03 2014-11-04 Gilead Sciences, Inc. Process and intermediates for preparing integrase inhibitors
WO2016081464A1 (fr) * 2014-11-17 2016-05-26 Nirogyone Therapeutics, Inc. Modulateurs de transport des monocarboxylates et leurs utilisations
KR102123365B1 (ko) * 2015-07-28 2020-06-16 바이옴 테라퓨틱스 리미티드 항박테리아 치료제 및 예방제
DE102017218119A1 (de) 2017-10-11 2019-04-11 Christian-Albrechts-Universität Zu Kiel In der Umwelt abbaubare Chinolon-Antibiotika mit Hemiaminal-Struktureinheit
CN108484577B (zh) * 2018-03-05 2021-03-30 复旦大学 一种嘧啶-喹诺酮类杂合物及其制备方法和用途
CN111087409B (zh) * 2018-10-24 2021-06-08 江阴安博生物医药有限公司 一种喹诺酮类化合物及其制备方法和应用
PL3897842T3 (pl) * 2018-12-18 2025-05-19 Elanco Tiergesundheit Ag Pochodne bicykliczne
CN109942546B (zh) * 2019-04-16 2022-04-08 西南大学 喹诺酮嘧啶类化合物及其制备方法和应用

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DE3639465A1 (de) 1986-11-18 1988-05-19 Hoechst Ag Optisch aktive gyrasehemmer, ihre herstellung und verwendung als antibiotika
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US5225413A (en) 1988-09-16 1993-07-06 Bayer-Aktiengesellschaft pH-neutral aqueous solutions of quinolone-carboxylic acids
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US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
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IT1251202B (it) * 1991-09-13 1995-05-04 Mediolanum Farmaceutici Spa 6-amminochinoloni, sintesi ed impiego come antibatterici
US5395936A (en) * 1993-06-04 1995-03-07 Manzo; Ruben H. 7-(4-[4-aminophenyl)sulphonyl]-1-piperazinyl fluorquinolonic derivatives and synthesis
DK0676199T3 (da) 1994-04-07 1999-02-08 Pfizer Anvendelse af trovafloxacin eller derivater deraf til fremstilling af et medikament til behandling af H. pylori-infektione
DE19519822A1 (de) 1995-05-31 1996-12-05 Bayer Ag Neue antibakterielle Mittel

Also Published As

Publication number Publication date
JP2003514812A (ja) 2003-04-22
US6967205B1 (en) 2005-11-22
ATE398117T1 (de) 2008-07-15
WO2001036408A1 (fr) 2001-05-25
DE60039183D1 (de) 2008-07-24
AU1747201A (en) 2001-05-30
EP1230235B1 (fr) 2008-06-11
EP1230235A1 (fr) 2002-08-14

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