SE9603171D0 - Solid phase synthesis - Google Patents

Solid phase synthesis

Info

Publication number: SE9603171D0
Authority: SE; Sweden
Prior art keywords: support; solid phase; phase synthesis; synthesis; oligonucleotides
Prior art date: 1996-08-30

Application number

SE9603171A

Other languages

English (en)

Inventor

Marek Kwiatkowski

Mats Nilsson

Ulf Landegren

Original Assignee

Marek Kwiatkowski

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-30

Filing date

1996-08-30

Publication date

1996-08-30

1996-08-30 Application filed by Marek Kwiatkowski filed Critical Marek Kwiatkowski

1996-08-30 Priority to SE9603171A priority Critical patent/SE9603171D0/sv

1996-08-30 Publication of SE9603171D0 publication Critical patent/SE9603171D0/sv

1997-08-27 Priority to PCT/SE1997/001418 priority patent/WO1998008857A1/en

1997-08-27 Priority to DE69725866T priority patent/DE69725866T2/de

1997-08-27 Priority to US09/254,048 priority patent/US6291669B1/en

1997-08-27 Priority to AT97936002T priority patent/ATE253074T1/de

1997-08-27 Priority to EP97936002A priority patent/EP0925306B1/en

1997-08-27 Priority to CA002264154A priority patent/CA2264154A1/en

1997-08-27 Priority to ES97936002T priority patent/ES2210555T3/es

1997-08-27 Priority to JP51155998A priority patent/JP2001505543A/ja

2001-08-02 Priority to US09/921,203 priority patent/US6429309B1/en

2002-03-25 Priority to US10/106,832 priority patent/US6646118B2/en

2003-10-14 Priority to US10/685,331 priority patent/US20050027116A1/en

Links

238000010532 solid phase synthesis reaction Methods 0.000 title abstract 2
108091034117 Oligonucleotide Proteins 0.000 abstract 2
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 2
230000015572 biosynthetic process Effects 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
238000003786 synthesis reaction Methods 0.000 abstract 2
238000011068 loading method Methods 0.000 abstract 1
239000002777 nucleoside Substances 0.000 abstract 1
150000003833 nucleoside derivatives Chemical class 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
239000007858 starting material Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Saccharide Compounds (AREA)
Catalysts (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

SE9603171A 1996-08-30 1996-08-30 Solid phase synthesis SE9603171D0 (sv)

Priority Applications (12)

Application Number	Priority Date	Filing Date	Title
SE9603171A SE9603171D0 (sv)	1996-08-30	1996-08-30	Solid phase synthesis
JP51155998A JP2001505543A (ja)	1996-08-30	1997-08-27	固相合成法
AT97936002T ATE253074T1 (de)	1996-08-30	1997-08-27	Festphasen-synthese
DE69725866T DE69725866T2 (de)	1996-08-30	1997-08-27	Festphasen-synthese
US09/254,048 US6291669B1 (en)	1996-08-30	1997-08-27	Solid phase synthesis
PCT/SE1997/001418 WO1998008857A1 (en)	1996-08-30	1997-08-27	Solid phase synthesis
EP97936002A EP0925306B1 (en)	1996-08-30	1997-08-27	Solid phase synthesis
CA002264154A CA2264154A1 (en)	1996-08-30	1997-08-27	Solid phase synthesis
ES97936002T ES2210555T3 (es)	1996-08-30	1997-08-27	Sistesis en fase solida.
US09/921,203 US6429309B1 (en)	1996-08-30	2001-08-02	Solid phase synthesis
US10/106,832 US6646118B2 (en)	1996-08-30	2002-03-25	Solid phase synthesis
US10/685,331 US20050027116A1 (en)	1996-08-30	2003-10-14	Solid phase synthesis

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9603171A SE9603171D0 (sv)	1996-08-30	1996-08-30	Solid phase synthesis

Publications (1)

Publication Number	Publication Date
SE9603171D0 true SE9603171D0 (sv)	1996-08-30

Family

ID=20403732

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE9603171A SE9603171D0 (sv)	1996-08-30	1996-08-30	Solid phase synthesis

Country Status (9)

Country	Link
US (4)	US6291669B1 (sv)
EP (1)	EP0925306B1 (sv)
JP (1)	JP2001505543A (sv)
AT (1)	ATE253074T1 (sv)
CA (1)	CA2264154A1 (sv)
DE (1)	DE69725866T2 (sv)
ES (1)	ES2210555T3 (sv)
SE (1)	SE9603171D0 (sv)
WO (1)	WO1998008857A1 (sv)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5854033A (en)	1995-11-21	1998-12-29	Yale University	Rolling circle replication reporter systems
SE9603171D0 (sv) *	1996-08-30	1996-08-30	Marek Kwiatkowski	Solid phase synthesis
US6309836B1 (en)	1999-10-05	2001-10-30	Marek Kwiatkowski	Compounds for protecting hydroxyls and methods for their use
US7572642B2 (en) *	2001-04-18	2009-08-11	Ambrigen, Llc	Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns
US6977148B2 (en) *	2001-10-15	2005-12-20	Qiagen Gmbh	Multiple displacement amplification
US6617137B2 (en) *	2001-10-15	2003-09-09	Molecular Staging Inc.	Method of amplifying whole genomes without subjecting the genome to denaturing conditions
US7297485B2 (en) *	2001-10-15	2007-11-20	Qiagen Gmbh	Method for nucleic acid amplification that results in low amplification bias
US20030153741A1 (en) *	2002-02-08	2003-08-14	Marek Kwiatkowski	Methods for separating oligonucleotides
US7553619B2 (en)	2002-02-08	2009-06-30	Qiagen Gmbh	Detection method using dissociated rolling circle amplification
WO2004011474A1 (en) *	2002-07-31	2004-02-05	Isis Pharmaceuticals, Inc.	Universal support media for synthesis of oligomeric compounds
US6653468B1 (en) *	2002-07-31	2003-11-25	Isis Pharmaceuticals, Inc.	Universal support media for synthesis of oligomeric compounds
US20040242897A1 (en) *	2002-07-31	2004-12-02	Guzaev Andrei P.	Universal support media for synthesis of oligomeric compounds
US7345163B2 (en)	2002-08-28	2008-03-18	Quiatech Ab	Process for separating and deprotecting oligonucleotides
US20040115643A1 (en) *	2002-12-12	2004-06-17	Lizardi Paul M.	Thermodynamic equilibrium extension of primers
AU2003299694A1 (en)	2002-12-20	2004-07-22	Qiagen Gmbh	Nucleic acid amplification
US7955795B2 (en) *	2003-06-06	2011-06-07	Qiagen Gmbh	Method of whole genome amplification with reduced artifact production
US9487823B2 (en)	2002-12-20	2016-11-08	Qiagen Gmbh	Nucleic acid amplification
US6977153B2 (en)	2002-12-31	2005-12-20	Qiagen Gmbh	Rolling circle amplification of RNA
US7202264B2 (en)	2003-01-31	2007-04-10	Isis Pharmaceuticals, Inc.	Supports for oligomer synthesis
US8043834B2 (en)	2003-03-31	2011-10-25	Qiagen Gmbh	Universal reagents for rolling circle amplification and methods of use
US20040248103A1 (en) *	2003-06-04	2004-12-09	Feaver William John	Proximity-mediated rolling circle amplification
US20050106589A1 (en) *	2003-11-17	2005-05-19	Hashem Akhavan-Tafti	Compositions and methods for releasing nucleic acids from solid phase binding materials
US20050130736A1 (en) *	2003-12-12	2005-06-16	Lottofone, Inc.	Prepaid wagering card
WO2005113804A1 (en) *	2004-05-20	2005-12-01	Trillion Genomics Limited	Use of mass labelled probes to detect target nucleic acids using mass spectrometry
US20060003651A1 (en) *	2004-07-01	2006-01-05	Building Materials Investment Corporation	Coating for granulated products to improve granule adhesion, staining, and tracking
CA2600851A1 (en)	2005-03-15	2006-09-21	Applera Corporation	The use of antibody-surrogate antigen systems for detection of analytes
US8309303B2 (en)	2005-04-01	2012-11-13	Qiagen Gmbh	Reverse transcription and amplification of RNA with simultaneous degradation of DNA
EP1762627A1 (de)	2005-09-09	2007-03-14	Qiagen GmbH	Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
US20080057499A1 (en) *	2006-02-06	2008-03-06	Affymetrix, Inc.	Methods for high specificity whole genome amplification and hybridization
CA2541567C (en) *	2006-03-31	2012-07-17	University Of Waterloo	Parallel soft spherical mimo receiver and decoding method
CA2750820A1 (en)	2009-01-27	2010-08-05	Qiagen Gaithersburg	Thermophilic helicase dependent amplification technology with endpoint homogenous fluorescent detection
WO2011150227A1 (en)	2010-05-26	2011-12-01	Qiagen Gaithersburg, Inc.	Quantitative helicase assay
US20140038182A1 (en)	2012-07-17	2014-02-06	Dna Logix, Inc.	Cooperative primers, probes, and applications thereof
US10114015B2 (en)	2013-03-13	2018-10-30	Meso Scale Technologies, Llc.	Assay methods
US9618510B2 (en)	2013-03-13	2017-04-11	Meso Scale Technologies, Llc.	Assay methods
KR102497054B1 (ko)	2014-05-15	2023-02-06	메소 스케일 테크놀러지즈, 엘엘시	개선된 분석 방법
CN112105628B (zh)	2018-03-13	2025-04-04	耶路撒冷希伯来大学伊森姆研究发展有限公司	高剪切固相合成
CA3292164A1 (en)	2018-09-25	2025-11-29	Co Diagnostics Inc	Allele-specific design of cooperative primers for improved nucleic acid variant genotyping
JP7727628B2 (ja)	2019-12-03	2025-08-21	アラマーバイオサイエンシーズ，インク．	核酸結合免疫サンドイッチアッセイ（ｎｕｌｉｓａ）
CA3179701A1 (en) *	2020-04-06	2021-10-14	Molecular Assemblies, Inc.	Reusable initiators for synthesizing nucleic acids

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5214134A (en) *	1990-09-12	1993-05-25	Sterling Winthrop Inc.	Process of linking nucleosides with a siloxane bridge
SE9003743D0 (sv) *	1990-11-26	1990-11-26	Pharmacia Ab	Method and means for oligonucleotide synthesis
FI943054L (sv) *	1991-12-24	1994-08-22	Tepnel Medical Ltd	Manipulering av nukleinsyrasekvenser
SE9603171D0 (sv)	1996-08-30	1996-08-30	Marek Kwiatkowski	Solid phase synthesis

1996
- 1996-08-30 SE SE9603171A patent/SE9603171D0/sv unknown
1997
- 1997-08-27 AT AT97936002T patent/ATE253074T1/de not_active IP Right Cessation
- 1997-08-27 WO PCT/SE1997/001418 patent/WO1998008857A1/en not_active Ceased
- 1997-08-27 EP EP97936002A patent/EP0925306B1/en not_active Expired - Lifetime
- 1997-08-27 DE DE69725866T patent/DE69725866T2/de not_active Expired - Fee Related
- 1997-08-27 US US09/254,048 patent/US6291669B1/en not_active Expired - Fee Related
- 1997-08-27 CA CA002264154A patent/CA2264154A1/en not_active Abandoned
- 1997-08-27 JP JP51155998A patent/JP2001505543A/ja not_active Abandoned
- 1997-08-27 ES ES97936002T patent/ES2210555T3/es not_active Expired - Lifetime
2001
- 2001-08-02 US US09/921,203 patent/US6429309B1/en not_active Expired - Fee Related
2002
- 2002-03-25 US US10/106,832 patent/US6646118B2/en not_active Expired - Fee Related
2003
- 2003-10-14 US US10/685,331 patent/US20050027116A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20020035247A1 (en)	2002-03-21
US20050027116A1 (en)	2005-02-03
WO1998008857A1 (en)	1998-03-05
EP0925306A1 (en)	1999-06-30
CA2264154A1 (en)	1998-03-05
US20020177698A1 (en)	2002-11-28
DE69725866D1 (de)	2003-12-04
US6646118B2 (en)	2003-11-11
US6429309B1 (en)	2002-08-06
DE69725866T2 (de)	2004-09-09
JP2001505543A (ja)	2001-04-24
EP0925306B1 (en)	2003-10-29
ATE253074T1 (de)	2003-11-15
ES2210555T3 (es)	2004-07-01
US6291669B1 (en)	2001-09-18

Publication	Publication Date	Title
DE69725866D1 (de)	2003-12-04	Festphasen-synthese
FI955530A7 (sv)	1996-01-12	Katalytbärare, förfarande för framställning av en prekursorgel för en katalytbärare
DE68908194D1 (de)	1993-09-16	Anlage zur plasma-chemischen dampfphasenreaktion.
MX16842A (es)	1993-04-01	Procedimiento para sintetizar derivados de sacarosa mediante reaccion regioselectiva.
DE69634486D1 (de)	2005-04-21	Drathloses eeg system für eine effiziente schall-evozierte reaktion
MX9804732A (es)	1998-11-30	Uso de catalizadores de cedazo molecular de poro pequeño conteniendo metal de transicion en conversion de oxigenados.
AU1858597A (en)	1998-09-09	Olefin plant recovery system employing catalytic distillation
NO942998L (no)	1995-02-15	Fremgangsmåte for dehydrogenering av et alkan, samt alkan-dehydrogeneringskatalysator
MX9101523A (es)	1992-06-05	Catalizador para la sintesis de 3,4-poliisopreno cristalino
PT1312609E (pt)	2006-05-31	Compostos de acido e ester boronico, sinteses e utilizacoes
DE69802909D1 (de)	2002-01-24	Heterogenes dampfphasencarbonylierunsverfahren
DE69611442D1 (de)	2001-02-08	Enzymatische synthese von glykosidischen verbindungen
FI943556A7 (sv)	1995-01-30	Förfarande för framställning av katalysatorer på bärare
AU7025891A (en)	1991-08-08	Catalyst system for distillation reactor
NO913570D0 (no)	1991-09-10	Katalysator til dampreforming av hydrokarboner.
IT1283232B1 (it)	1998-04-16	Procedimento per la sintesi di 2-buten-1, 4-diesteri
EP0830136A4 (en)	2001-01-24	NEW SYNTHETIC CRYPTOPHYCINE
ZA987554B (en)	2000-02-21	Methods for the solid phase synthesis of substituted indole compounds.
NO995136D0 (no)	1999-10-21	Fremgangsmåte ved fremstilling av höy-aktive hydrokarbon syntesekatalysatorer, og katalysatorsammensetninger
FR2741064B1 (fr)	1997-12-12	Procede de conversion de gaz de synthese en hydrocarbures
AU3477599A (en)	1999-10-25	Solid phase synthesis of organic compounds via phosphitylating reagents
NO994414D0 (no)	1999-09-10	Understöttet katalysatorsystem for polymerisering av alk-1-ener
ZA982860B (en)	1999-10-04	Catalyst system for high yield synthesis of polyolefins.
DK0906154T3 (da)	2001-10-08	Fremgangsmåde til præsulfidering af carbonhydridomdannelseskatalysatorer
NO985462L (no)	1998-11-23	Karbohydrat-derivater og fastfase-syntese derav

SE9603171D0 - Solid phase synthesis - Google Patents

Info

Links

Classifications

Landscapes

Priority Applications (12)

Applications Claiming Priority (1)

Publications (1)

Family

ID=20403732

Family Applications (1)

Country Status (9)

Families Citing this family (40)

Family Cites Families (4)

Also Published As

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