SE8902076D0 - Derivatives of quinoline-3-carboxanilide - Google Patents
Derivatives of quinoline-3-carboxanilideInfo
- Publication number
- SE8902076D0 SE8902076D0 SE8902076A SE8902076A SE8902076D0 SE 8902076 D0 SE8902076 D0 SE 8902076D0 SE 8902076 A SE8902076 A SE 8902076A SE 8902076 A SE8902076 A SE 8902076A SE 8902076 D0 SE8902076 D0 SE 8902076D0
- Authority
- SE
- Sweden
- Prior art keywords
- group
- carboxanilide
- quinoline
- derivatives
- methoxy
- Prior art date
Links
- LQEPEEBJMGRUTB-UHFFFAOYSA-N n-phenylquinoline-3-carboxamide Chemical class C=1N=C2C=CC=CC2=CC=1C(=O)NC1=CC=CC=C1 LQEPEEBJMGRUTB-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001767 cationic compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 150000002892 organic cations Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
- Quinoline Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8902076A SE8902076D0 (sv) | 1989-06-09 | 1989-06-09 | Derivatives of quinoline-3-carboxanilide |
| NZ233860A NZ233860A (en) | 1989-06-09 | 1990-05-30 | Substituted quinoline derivatives |
| CA002033211A CA2033211A1 (en) | 1989-06-09 | 1990-05-31 | Derivatives of quinoline-3-carboxanilide |
| EP90909805A EP0429627B1 (en) | 1989-06-09 | 1990-05-31 | Derivatives of quinoline-3-carboxanilide |
| DE69022368T DE69022368T2 (de) | 1989-06-09 | 1990-05-31 | Quinolin-3-carboxanilid-derivate. |
| JP2509778A JPH04500373A (ja) | 1989-06-09 | 1990-05-31 | キノリン―3―カルボキシアニリドの誘導体 |
| PCT/SE1990/000375 WO1990015052A1 (en) | 1989-06-09 | 1990-05-31 | Derivatives of quinoline-3-carboxanilide |
| AU59234/90A AU648026B2 (en) | 1989-06-09 | 1990-05-31 | Derivatives of quinoline-3-carboxanilide |
| ES90909805T ES2077071T3 (es) | 1989-06-09 | 1990-05-31 | Derivados de quinolin-3-carboxamida. |
| AT90909805T ATE127791T1 (de) | 1989-06-09 | 1990-05-31 | Quinolin-3-carboxanilid-derivate. |
| DK90909805.5T DK0429627T3 (da) | 1989-06-09 | 1990-05-31 | Derivater af quinolin-3-carboxanilider |
| US08/102,393 US5310913A (en) | 1989-06-09 | 1993-08-05 | Derivatives of quinoline-3-carboxanilide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8902076A SE8902076D0 (sv) | 1989-06-09 | 1989-06-09 | Derivatives of quinoline-3-carboxanilide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE8902076D0 true SE8902076D0 (sv) | 1989-06-09 |
Family
ID=20376220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8902076A SE8902076D0 (sv) | 1989-06-09 | 1989-06-09 | Derivatives of quinoline-3-carboxanilide |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0429627B1 (sv) |
| JP (1) | JPH04500373A (sv) |
| AT (1) | ATE127791T1 (sv) |
| AU (1) | AU648026B2 (sv) |
| CA (1) | CA2033211A1 (sv) |
| DE (1) | DE69022368T2 (sv) |
| DK (1) | DK0429627T3 (sv) |
| ES (1) | ES2077071T3 (sv) |
| NZ (1) | NZ233860A (sv) |
| SE (1) | SE8902076D0 (sv) |
| WO (1) | WO1990015052A1 (sv) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310913A (en) * | 1989-06-09 | 1994-05-10 | Kabi Pharmacia Aktiebolag | Derivatives of quinoline-3-carboxanilide |
| US5268378A (en) * | 1990-05-31 | 1993-12-07 | Merck Sharp & Dohme, Limited | Dioxo-tetrahydroquinoline derivatives |
| GB9108547D0 (en) * | 1991-04-22 | 1991-06-05 | Fujisawa Pharmaceutical Co | Quinoline derivatives |
| DE4138820A1 (de) * | 1991-11-26 | 1993-05-27 | Basf Ag | Chinolin-3-carbonsaeureamide, deren herstellung und verwendung |
| GB9311562D0 (en) * | 1993-06-04 | 1993-07-21 | Fujisawa Pharmaceutical Co | Heterocyclic derivatives |
| GB9404378D0 (en) * | 1994-03-07 | 1994-04-20 | Fujisawa Pharmaceutical Co | Quinoline derivatives |
| SE9400809D0 (sv) * | 1994-03-10 | 1994-03-10 | Pharmacia Ab | New use of quinoline-3-carboxamide compounds |
| SE9400810D0 (sv) * | 1994-03-10 | 1994-03-10 | Pharmacia Ab | New use of Quinoline-3-carboxamide compounds |
| KR20000022040A (ko) * | 1996-06-20 | 2000-04-25 | 보오드 오브 리젠츠, 더 유니버시티 오브 텍사스 시스템 | 약학적 활성 제제를 제공하기 위한 화합물, 방법 및 그의 용도 |
| JP2000256323A (ja) | 1999-01-08 | 2000-09-19 | Japan Tobacco Inc | 2−オキソキノリン化合物及びその医薬用途 |
| RU2162326C1 (ru) * | 1999-11-12 | 2001-01-27 | Научно-исследовательский институт психического здоровья Томского научного центра СО РАМН | Средство, стимулирующее фагоцитоз |
| US8314124B2 (en) | 2004-02-06 | 2012-11-20 | Active Biotech Ab | Crystalline salts of quinoline compounds and methods for preparing them |
| SE0400235D0 (sv) | 2004-02-06 | 2004-02-06 | Active Biotech Ab | New composition containing quinoline compounds |
| KR101440982B1 (ko) | 2005-10-19 | 2014-09-17 | 테바 파마슈티컬 인더스트리즈 리미티드 | 라퀴니모드 나트륨의 결정 및 이의 제조방법 |
| US7989473B2 (en) | 2006-06-12 | 2011-08-02 | Teva Pharmaceutical Industries, Ltd. | Stable laquinimod preparations |
| US8178127B2 (en) | 2007-12-20 | 2012-05-15 | Teva Pharmaceuticals Industries, Ltd. | Stable laquinimod preparations |
| JP2012502038A (ja) | 2008-09-03 | 2012-01-26 | テバ ファーマシューティカル インダストリーズ リミティド | 免疫機能の2−オキソ−1,2−ジヒドロ−キノリンモジュレーター |
| JP6215238B2 (ja) * | 2012-02-16 | 2017-10-18 | テバ ファーマシューティカル インダストリーズ リミティド | N−エチル−n−フェニル−1,2−ジヒドロ−4,5−ジ−ヒドロキシ−1−メチル−2−オキソ−3−キノリンカルボキサミド、その製剤、および使用 |
| TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
| HK1215210A1 (zh) | 2012-11-07 | 2016-08-19 | Teva Pharmaceutical Industries Ltd. | 拉喹莫德胺盐 |
| US9233927B2 (en) | 2013-03-14 | 2016-01-12 | Teva Pharmaceutical Industries, Ltd. | Crystals of laquinimod sodium and improved process for the manufacture thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE52670B1 (en) * | 1981-03-03 | 1988-01-20 | Leo Ab | Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation |
| DE3420116A1 (de) * | 1984-05-30 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | Immunstimulierende mittel |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
-
1989
- 1989-06-09 SE SE8902076A patent/SE8902076D0/sv unknown
-
1990
- 1990-05-30 NZ NZ233860A patent/NZ233860A/en unknown
- 1990-05-31 EP EP90909805A patent/EP0429627B1/en not_active Expired - Lifetime
- 1990-05-31 AT AT90909805T patent/ATE127791T1/de not_active IP Right Cessation
- 1990-05-31 DE DE69022368T patent/DE69022368T2/de not_active Expired - Fee Related
- 1990-05-31 CA CA002033211A patent/CA2033211A1/en not_active Abandoned
- 1990-05-31 AU AU59234/90A patent/AU648026B2/en not_active Ceased
- 1990-05-31 WO PCT/SE1990/000375 patent/WO1990015052A1/en not_active Ceased
- 1990-05-31 JP JP2509778A patent/JPH04500373A/ja active Pending
- 1990-05-31 ES ES90909805T patent/ES2077071T3/es not_active Expired - Lifetime
- 1990-05-31 DK DK90909805.5T patent/DK0429627T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| JPH04500373A (ja) | 1992-01-23 |
| ES2077071T3 (es) | 1995-11-16 |
| CA2033211A1 (en) | 1990-12-10 |
| EP0429627B1 (en) | 1995-09-13 |
| AU5923490A (en) | 1991-01-07 |
| AU648026B2 (en) | 1994-04-14 |
| WO1990015052A1 (en) | 1990-12-13 |
| EP0429627A1 (en) | 1991-06-05 |
| NZ233860A (en) | 1991-04-26 |
| DE69022368D1 (de) | 1995-10-19 |
| DE69022368T2 (de) | 1996-05-02 |
| DK0429627T3 (da) | 1995-11-20 |
| ATE127791T1 (de) | 1995-09-15 |
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