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SE8802997D0 - AMINE DERIVATIVES AND ITS SALTS, PROCEDURES FOR PREPARING THEREOF AND AGENTS CONTAINING THEMSELVES - Google Patents

AMINE DERIVATIVES AND ITS SALTS, PROCEDURES FOR PREPARING THEREOF AND AGENTS CONTAINING THEMSELVES

Info

Publication number
SE8802997D0
SE8802997D0 SE8802997A SE8802997A SE8802997D0 SE 8802997 D0 SE8802997 D0 SE 8802997D0 SE 8802997 A SE8802997 A SE 8802997A SE 8802997 A SE8802997 A SE 8802997A SE 8802997 D0 SE8802997 D0 SE 8802997D0
Authority
SE
Sweden
Prior art keywords
salts
procedures
preparing
amine derivatives
agents containing
Prior art date
Application number
SE8802997A
Other languages
Swedish (sv)
Other versions
SE8802997L (en
SE466347B (en
Inventor
S Hirai
H Hirano
H Arai
H Shibata
Y Kusayanagi
K Hashiba
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP63205047A external-priority patent/JPH01131172A/en
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of SE8802997D0 publication Critical patent/SE8802997D0/en
Publication of SE8802997L publication Critical patent/SE8802997L/en
Publication of SE466347B publication Critical patent/SE466347B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

N'-Methylsulphonyl-N"-furyl methylthio-ethyl-guanidine cpds. of formula (I) and their salts are prepared. R is 4-hydroxyphenyl, 4- carbamoylphenyl or 3-methanesulphonylaminophenyl. (I) are histamine H2 receptor antagonists, useful as antiulcer agents with better activity and stability and lower toxicity than known cpds. of JP 88458/84 and 97958/85. In mice all the cpds. had intravenous LD50 at least 0.1 g/kg. and the normal dose is 1 microg-10 mg/kg/ day in 1-4 portions.
SE8802997A 1987-08-28 1988-08-26 AMINARY DERIVATIVES AND ITS SALT, PROCEDURES FOR PREPARING THEREOF AND Means against their containing SE466347B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21429287 1987-08-28
JP63205047A JPH01131172A (en) 1987-08-28 1988-08-18 Amine derivatives and their salts, their production methods, and antiulcer agents containing them

Publications (3)

Publication Number Publication Date
SE8802997D0 true SE8802997D0 (en) 1988-08-26
SE8802997L SE8802997L (en) 1989-03-01
SE466347B SE466347B (en) 1992-02-03

Family

ID=26514815

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8802997A SE466347B (en) 1987-08-28 1988-08-26 AMINARY DERIVATIVES AND ITS SALT, PROCEDURES FOR PREPARING THEREOF AND Means against their containing

Country Status (13)

Country Link
AU (1) AU595134B2 (en)
BE (1) BE1003231A4 (en)
CA (1) CA1305714C (en)
CH (1) CH675244A5 (en)
DE (1) DE3828869A1 (en)
DK (1) DK476788A (en)
ES (1) ES2014041A6 (en)
FI (1) FI89480C (en)
FR (1) FR2619816B1 (en)
GB (1) GB2209163B (en)
IT (1) IT1235015B (en)
NL (1) NL192820C (en)
SE (1) SE466347B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0730064B2 (en) * 1989-08-17 1995-04-05 協和醗酵工業株式会社 Furan derivative
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
US4233302A (en) * 1977-12-23 1980-11-11 Glaxo Group Limited Amine derivatives and pharmaceutical compositions containing them
DE3108753A1 (en) * 1981-03-07 1982-09-16 Degussa Ag, 6000 Frankfurt Substituted alkylphenylsulphonylguanidines with a heterocyclic radical
CA1254212A (en) * 1982-11-12 1989-05-16 Shiro Hirai Amine derivatives, salts thereof, process for preparing the same and an anti-ulcer agent containing the same

Also Published As

Publication number Publication date
SE8802997L (en) 1989-03-01
IT8848303A0 (en) 1988-08-26
AU595134B2 (en) 1990-03-22
DE3828869A1 (en) 1989-03-09
SE466347B (en) 1992-02-03
GB2209163A (en) 1989-05-04
IT1235015B (en) 1992-06-16
DE3828869C2 (en) 1990-07-19
ES2014041A6 (en) 1990-06-16
FI883967A0 (en) 1988-08-26
GB2209163B (en) 1991-04-24
FI883967L (en) 1989-03-01
NL8802089A (en) 1989-03-16
DK476788A (en) 1989-03-01
GB8819886D0 (en) 1988-09-21
AU2156688A (en) 1989-03-02
NL192820C (en) 1998-03-04
FR2619816B1 (en) 1994-09-02
FI89480B (en) 1993-06-30
DK476788D0 (en) 1988-08-26
BE1003231A4 (en) 1992-02-04
FI89480C (en) 1993-10-11
CA1305714C (en) 1992-07-28
CH675244A5 (en) 1990-09-14
NL192820B (en) 1997-11-03
FR2619816A1 (en) 1989-03-03

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