SE8503055D0 - PIPERONYLCARBOXAMIDO DERIVATIVES - Google Patents
PIPERONYLCARBOXAMIDO DERIVATIVESInfo
- Publication number
- SE8503055D0 SE8503055D0 SE8503055A SE8503055A SE8503055D0 SE 8503055 D0 SE8503055 D0 SE 8503055D0 SE 8503055 A SE8503055 A SE 8503055A SE 8503055 A SE8503055 A SE 8503055A SE 8503055 D0 SE8503055 D0 SE 8503055D0
- Authority
- SE
- Sweden
- Prior art keywords
- group
- hydrogen atom
- alkyl group
- methods
- compounds
- Prior art date
Links
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000005117 dialkylcarbamoyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000004950 trifluoroalkyl group Chemical group 0.000 abstract 1
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Novel neuropharmacologically active compounds of the formula <IMAGE> wherein R<1> is a hydrogen atom or a lower alkyl group, Z is oxygen or CHR<1>, R<2> is a hydrogen atom, a halogen atom, an alkyl group or a trifluoro alkyl group or an alkylthio group, A<1> is a hydrogen atom or OR<4>, wherein R<4> is a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group or a mono- or dialkyl-carbamoyl group. R<3> is a hydrogen atom, an alkyl group, a cykloalkyl group, an alkenyl or an alkynyl group, a phenyl group or a substituted phenyl group. n is an integer 1, 2 or a physiologically acceptable salt or optical isomer thereof, the corresponding free acid inter mediates, and methods for their preparation, pharmaceutical preparations containing the compounds and methods for their therapeutical use.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8503055A SE8503055D0 (en) | 1985-06-19 | 1985-06-19 | PIPERONYLCARBOXAMIDO DERIVATIVES |
| GB08614176A GB2176785A (en) | 1985-06-19 | 1986-06-11 | Annellated benzamide derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8503055A SE8503055D0 (en) | 1985-06-19 | 1985-06-19 | PIPERONYLCARBOXAMIDO DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE8503055D0 true SE8503055D0 (en) | 1985-06-19 |
Family
ID=20360639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8503055A SE8503055D0 (en) | 1985-06-19 | 1985-06-19 | PIPERONYLCARBOXAMIDO DERIVATIVES |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB2176785A (en) |
| SE (1) | SE8503055D0 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0278915B1 (en) * | 1987-02-13 | 1991-11-27 | Ciba-Geigy Ag | Diphenylethylene derivatives |
| US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
| US5186921A (en) * | 1989-04-17 | 1993-02-16 | Trustees Of The University Of Pennsylvania | Dopamine receptor ligands and image agents |
| US5122361A (en) * | 1989-04-17 | 1992-06-16 | Trustees Of The University Of Pennsylvania | Dopamine receptor ligands and imaging agents |
| GB9119692D0 (en) * | 1991-09-14 | 1991-10-30 | Smithkline Beecham Plc | Pharmaceuticals |
| WO1993005038A1 (en) * | 1991-09-12 | 1993-03-18 | Smithkline Beecham Plc | 5-ht4 receptor antagonists |
| MA22647A1 (en) * | 1991-09-14 | 1993-04-01 | Smithkline Beecham Plc | PROCESS FOR THE PREPARATION OF AN ESTER OR AMIDE OF A NEW PRODUCT. |
| FR2682953B1 (en) * | 1991-10-23 | 1995-04-21 | Inst Nat Sante Rech Med | NOVEL NAPHTHAMIDE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THE THERAPEUTIC FIELD. |
| AU667874B2 (en) * | 1992-02-06 | 1996-04-18 | Smithkline Beecham Plc | Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists |
| GB9219163D0 (en) * | 1992-09-10 | 1992-10-28 | Smithkline Beecham Plc | Pharmaceuticals |
| GR1002176B (en) * | 1992-10-19 | 1996-03-07 | Smithkline Beecham Plc | Pharmaceutical substances. |
| WO1994010174A1 (en) * | 1992-11-05 | 1994-05-11 | Smithkline Beecham Plc | Piperidine derivatives as 5-ht4 receptor antagonists |
| ES2065238B1 (en) * | 1992-11-20 | 1995-10-01 | Smithkline Beecham Plc | BENZENE DERIVATIVES CONDENSED WITH ANTAGONISTIC ACTIVITY OF THE 5-HT4 RECEPTOR, PROCEDURE FOR ITS PREPARATION, COMPOSITIONS CONTAINING THEM AND APPLICATIONS. |
| GB9312348D0 (en) * | 1993-06-16 | 1993-07-28 | Smithkline Beecham Plc | Pharmaceuticals |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2360305A1 (en) * | 1976-08-04 | 1978-03-03 | Ile De France | NEW 2,3-ALKYLENE BIS (OXY) BENZAMIDE SUBSTITUTES, THEIR DERIVATIVES AND THEIR PREPARATION METHODS |
| JPS59186969A (en) * | 1983-04-08 | 1984-10-23 | Yoshitomi Pharmaceut Ind Ltd | Benzofuran and benzopyran carboxamide derivatives |
| CA1297877C (en) * | 1983-12-22 | 1992-03-24 | Daniel Lednicer | Benzofurancarboxamides useful as antiemetic or antipsychotic agents |
-
1985
- 1985-06-19 SE SE8503055A patent/SE8503055D0/en unknown
-
1986
- 1986-06-11 GB GB08614176A patent/GB2176785A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| GB8614176D0 (en) | 1986-07-16 |
| GB2176785A (en) | 1987-01-07 |
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