SE8402561D0 - PHARMACEUTICAL COMPOSITION - Google Patents
PHARMACEUTICAL COMPOSITIONInfo
- Publication number
- SE8402561D0 SE8402561D0 SE8402561A SE8402561A SE8402561D0 SE 8402561 D0 SE8402561 D0 SE 8402561D0 SE 8402561 A SE8402561 A SE 8402561A SE 8402561 A SE8402561 A SE 8402561A SE 8402561 D0 SE8402561 D0 SE 8402561D0
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- pharmaceutical composition
- ester
- pyrrolidone
- aliphatic
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 abstract 1
- ZMGMDXCADSRNCX-UHFFFAOYSA-N 5,6-dihydroxy-1,3-diazepan-2-one Chemical compound OC1CNC(=O)NCC1O ZMGMDXCADSRNCX-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000007945 N-acyl ureas Chemical class 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- -1 alkyl amide Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A pharmaceutical composition for administration to the skin comprises a pharmaceutical agent, e.g. benzodiazepine, and a percutaneous carrier liquid comprising: A) a 5-24C aliphatic or cycloaliphatic hydrocarbon which may be halo-substituted, an ester of an alcohol and a 7-18C aliphatic carboxylic acid, a C10-18 mono- or di-ether, and/or a C11-15 ketone; and B) a thiogylercol, lactic acid or ester, cyclic urea, alkyl or acyl urea, alkyl amide and/or pyrrolidone or N-alkyl pyrrolidone.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49673283A | 1983-05-20 | 1983-05-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8402561D0 true SE8402561D0 (en) | 1984-05-11 |
| SE8402561L SE8402561L (en) | 1984-11-21 |
Family
ID=23973888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8402561A SE8402561L (en) | 1983-05-20 | 1984-05-11 | PHARMACEUTICAL COMPOSITION |
Country Status (8)
| Country | Link |
|---|---|
| CA (1) | CA1225594A (en) |
| CH (1) | CH657531A5 (en) |
| DE (1) | DE3418565C2 (en) |
| DK (1) | DK239984A (en) |
| FR (1) | FR2547503B1 (en) |
| GB (1) | GB2141025B (en) |
| NL (1) | NL8401422A (en) |
| SE (1) | SE8402561L (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4637930A (en) * | 1984-02-08 | 1987-01-20 | Yamanouchi Pharmaceutical Co, Ltd. | Transdermal formulation of nicardipine hydrochloride |
| JPS61280426A (en) * | 1985-06-04 | 1986-12-11 | Ikeda Mohandou:Kk | Anti-inflammatory and analgesic application agent |
| US4826686A (en) * | 1985-12-14 | 1989-05-02 | Boehringer Ingelheim Kg | Therapeutic system |
| CH666621A5 (en) * | 1986-06-27 | 1988-08-15 | Ciba Geigy Ag | TOPICALLY APPLICABLE PHARMACEUTICAL COMPOSITIONS WITH SYSTEMIC EFFECT. |
| US4861764A (en) * | 1986-11-17 | 1989-08-29 | Macro Chem. Corp. | Percutaneous absorption enhancers, compositions containing same and method of use |
| GB8718886D0 (en) * | 1987-08-10 | 1987-09-16 | Ici America Inc | Composition |
| CA1334646C (en) * | 1988-04-08 | 1995-03-07 | James Vanolden Peck | Transdermal penetration enhancers |
| JPH03236317A (en) * | 1989-12-06 | 1991-10-22 | Sansei Seiyaku Kk | Dopamine derivative-containing percutaneous |
| US5246949A (en) * | 1989-12-06 | 1993-09-21 | Sansho Co., Ltd. | Preparation for endermism containing dopamine derivatives |
| WO1994021262A1 (en) * | 1993-03-17 | 1994-09-29 | Alza Corporation | Device for the transdermal administration of alprazolam |
| DE4432429A1 (en) * | 1994-09-12 | 1996-03-14 | Heinz Prahm | Pharmaceutical concentrates contg. lactic acid |
| US5693335A (en) * | 1995-06-07 | 1997-12-02 | Cygnus, Inc. | Skin permeation enhancer composition for use with sex steroids |
| DE19949202A1 (en) * | 1999-10-13 | 2001-05-03 | Lohmann Therapie Syst Lts | Transdermal therapeutic system for the delivery of acetylsalicylic acid and / or salicylic acid |
| US20070083186A1 (en) * | 2005-09-30 | 2007-04-12 | Darrick Carter | Transdermal drug delivery systems, devices, and methods employing novel pharmaceutical vehicles |
| JP2009522011A (en) | 2005-12-30 | 2009-06-11 | Tti・エルビュー株式会社 | Iontophoresis system, apparatus and method for delivering an active substance to a biological interface |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1158283A (en) * | 1965-10-21 | 1969-07-16 | Foster Milburn Company | Composition to be Applied to Skin and Process for Preparing Same. |
| FR2001768A1 (en) * | 1968-02-12 | 1969-10-03 | Gillette Co | N-Alkyl-2-pyrrolidone to improve cutaneous absorption - methyl, ethyl and n-butyl pyrrolidone(s), opt. with water and/or ethanol give improved skin penetration |
| SE325667B (en) * | 1968-03-06 | 1970-07-06 | Medisan Ab | |
| US3472931A (en) * | 1969-01-17 | 1969-10-14 | Foster Milburn Co | Percutaneous absorption with lower alkyl amides |
| GB1404583A (en) * | 1971-10-08 | 1975-09-03 | Vymatt Sa | Urea compositions and methods of preparation thereof |
| GB1504302A (en) * | 1974-08-23 | 1978-03-15 | Fisons Ltd | Sedative method and composition |
| US3957994A (en) * | 1974-12-19 | 1976-05-18 | Nelson Research & Development Company | Topical anti-inflammatory composition and method of use |
| US3932653A (en) * | 1974-12-19 | 1976-01-13 | Nelson Research & Development Co. | Composition and method for topical administration of griseofulvin |
| US4017641A (en) * | 1975-01-31 | 1977-04-12 | The Procter & Gamble Company | Skin moisturizing compositions containing 2-pyrrolidinone |
| GB1538903A (en) * | 1975-04-11 | 1979-01-24 | Nelson Res & Dev | Carrier for a topically applied physiologically active agent or cosmetic agent |
| US4316893A (en) * | 1975-06-19 | 1982-02-23 | Nelson Research & Development Co. | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
| US4038417A (en) * | 1975-06-19 | 1977-07-26 | Nelson Research & Development Company | Method for treatment of psoriasis |
| CA1165240A (en) * | 1980-07-09 | 1984-04-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
| FR2502951B1 (en) * | 1981-04-06 | 1985-12-06 | Sandoz Sa | TOPICAL PHARMACEUTICAL COMPOSITIONS IN THE FORM OF A MICRO-EMULSION |
-
1984
- 1984-04-25 CA CA000452790A patent/CA1225594A/en not_active Expired
- 1984-05-04 NL NL8401422A patent/NL8401422A/en not_active Application Discontinuation
- 1984-05-11 SE SE8402561A patent/SE8402561L/en not_active Application Discontinuation
- 1984-05-15 DK DK239984A patent/DK239984A/en not_active Application Discontinuation
- 1984-05-17 GB GB08412569A patent/GB2141025B/en not_active Expired
- 1984-05-18 DE DE19843418565 patent/DE3418565C2/en not_active Expired
- 1984-05-18 FR FR8407796A patent/FR2547503B1/en not_active Expired
- 1984-05-18 CH CH245984A patent/CH657531A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB8412569D0 (en) | 1984-06-20 |
| CH657531A5 (en) | 1986-09-15 |
| DK239984A (en) | 1984-11-21 |
| FR2547503A1 (en) | 1984-12-21 |
| GB2141025A (en) | 1984-12-12 |
| FR2547503B1 (en) | 1987-11-20 |
| GB2141025B (en) | 1986-09-17 |
| CA1225594A (en) | 1987-08-18 |
| NL8401422A (en) | 1984-12-17 |
| DE3418565A1 (en) | 1984-11-22 |
| DK239984D0 (en) | 1984-05-15 |
| DE3418565C2 (en) | 1992-05-27 |
| SE8402561L (en) | 1984-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8402561-8 Effective date: 19880917 |