[go: up one dir, main page]

SE8207476L - NEW HETEROCYCLIC ETHIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF - Google Patents

NEW HETEROCYCLIC ETHIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF

Info

Publication number
SE8207476L
SE8207476L SE8207476A SE8207476A SE8207476L SE 8207476 L SE8207476 L SE 8207476L SE 8207476 A SE8207476 A SE 8207476A SE 8207476 A SE8207476 A SE 8207476A SE 8207476 L SE8207476 L SE 8207476L
Authority
SE
Sweden
Prior art keywords
general formula
image
new
defined above
procedures
Prior art date
Application number
SE8207476A
Other languages
Swedish (sv)
Other versions
SE8207476D0 (en
SE453084B (en
Inventor
K Lempert
G Doleschall
J Fetter
G Hornyak
J Nyitrai
G Simig
K Zauer
T Gizur
K Harsanyi
G Fekete
L Szporny
G Hajos
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE8207476D0 publication Critical patent/SE8207476D0/en
Publication of SE8207476L publication Critical patent/SE8207476L/en
Publication of SE453084B publication Critical patent/SE453084B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

New compounds of the general formula (I), <IMAGE> wherein Y<1> and Y<2> form together a removable carbonyl protecting group and X is a selectively removable esterifying group, are prepared in the way that a compound of the general formula (IV), <IMAGE> wherein Y<1> and Y<2> are as defined above, is nitrated and then reduced, the resulting new compound of the general formula (III), wherein <IMAGE> Y<1> and Y<2> are as defined above and A stands for nitro group and then for amino group, is converted into a new ester of the general formula (II), wherein Y<1>, Y<2> and X are as defined above, in a manner known per se, <IMAGE> and the aminophenyl protecting group of the resulting compound is split off. The new compounds of the general formula (I) can be applied primarily as intermediates in the synthesis of thienamycin or thienamycin analogues.
SE8207476A 1981-12-30 1982-12-29 AZETIDINON ETHYAC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF SE453084B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU814013A HU184496B (en) 1981-12-30 1981-12-30 Process for producing new azetidinon-acetic acid derivatives

Publications (3)

Publication Number Publication Date
SE8207476D0 SE8207476D0 (en) 1982-12-29
SE8207476L true SE8207476L (en) 1983-07-01
SE453084B SE453084B (en) 1988-01-11

Family

ID=10966510

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8207476A SE453084B (en) 1981-12-30 1982-12-29 AZETIDINON ETHYAC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF

Country Status (19)

Country Link
JP (1) JPS58118564A (en)
AT (1) AT378770B (en)
AU (1) AU555597B2 (en)
BE (1) BE895487A (en)
CA (1) CA1189866A (en)
CH (1) CH656123A5 (en)
DE (1) DE3248673A1 (en)
ES (1) ES8405762A1 (en)
FI (1) FI824519L (en)
FR (1) FR2518996B1 (en)
GB (1) GB2114125B (en)
GR (1) GR77071B (en)
HU (1) HU184496B (en)
IT (1) IT1210969B (en)
LU (1) LU84565A1 (en)
NL (1) NL8205068A (en)
PL (1) PL137594B1 (en)
SE (1) SE453084B (en)
ZA (1) ZA829594B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT71553B (en) * 1979-07-23 1981-12-14 Merck & Co Inc Process for the preparation of thienamycin and intermediates
JPS57167964A (en) * 1981-04-09 1982-10-16 Toyama Chem Co Ltd Preparation of (4r)-3-substituted-4-(substituted or unsubstituted carboxymethyl)-2-azetidinone derivative
JPS57176982A (en) * 1981-04-24 1982-10-30 Shionogi & Co Ltd Dioxolanylazetidinone compound, its preparation and use

Also Published As

Publication number Publication date
AU9196982A (en) 1983-07-07
FR2518996B1 (en) 1986-02-28
PL239886A1 (en) 1984-01-02
FI824519A7 (en) 1983-07-01
GB2114125A (en) 1983-08-17
PL137594B1 (en) 1986-06-30
NL8205068A (en) 1983-07-18
LU84565A1 (en) 1984-10-22
BE895487A (en) 1983-06-28
CA1189866A (en) 1985-07-02
FR2518996A1 (en) 1983-07-01
FI824519L (en) 1983-07-01
DE3248673A1 (en) 1983-07-07
AT378770B (en) 1985-09-25
CH656123A5 (en) 1986-06-13
SE8207476D0 (en) 1982-12-29
ES518721A0 (en) 1984-06-16
JPS58118564A (en) 1983-07-14
ZA829594B (en) 1983-10-26
SE453084B (en) 1988-01-11
FI824519A0 (en) 1982-12-30
GB2114125B (en) 1985-09-25
IT1210969B (en) 1989-09-29
GR77071B (en) 1984-09-05
ES8405762A1 (en) 1984-06-16
IT8225061A0 (en) 1982-12-30
HU184496B (en) 1984-08-28
ATA453282A (en) 1985-02-15
AU555597B2 (en) 1986-10-02

Similar Documents

Publication Publication Date Title
BG38639A3 (en) Method for preparing ester derivatives of 6- beta- hydroxymethylpenicillanic acid
FI853717L (en) 3-AMINO-2-BENZOYL-ACRYLIC SYRADER OCH FOERFARANDE FOER DERAS FRAMSTAELLNING.
ATE18197T1 (en) 1&#39;-AETHOXYCARBONYLOXYAETHYLESTER OF VALPONIC ACID, ITS PREPARATION AND FORMULATIONS CONTAINING THEM.
ES8106482A1 (en) Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them.
DE2965574D1 (en) Adamantylalkyloxy-carbonyl derivatives, their preparation and their use for the production of peptides
IE39741B1 (en) Phenyl-benzoig acid deritavies
ATE9225T1 (en) DERIVATIVES OF 5-HYDROXY-TETRAHYDRO-2-FURANONE.
GB1515060A (en) 3-hydroxymethylene-6,7-dimethoxy-2-methyl-4-oxo-1,2,3,4-tetrahydro-1-quinoline carboxylic acid esters
SE8207476L (en) NEW HETEROCYCLIC ETHIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF
GB1498535A (en) Heterocyclic compounds
ES8300701A1 (en) Heterocyclic compounds,method for preparing such compounds and pharmaceutical compositions containing them
SE8207475L (en) NEW HETEROCYCLIC ETHIC ACID DERIVATIVES AND A PROCEDURE FOR PREPARING THEREOF
SE8207477L (en) PROCEDURE FOR PREPARING HETEROCYCLIC ETHIC ACID DERIVATIVES
JPS55380A (en) Preparation of dibenzoxepin derivative
JPS5283436A (en) Preparation of intermediates for synthesis of prostaglandin
BR8103727A (en) PROCESSES FOR THE PRODUCTION OF A DIMETHACRYLIC ACID ESTER ITS APPLICATION AND SEALING OR ADHESIVE COMPOSITIONS BASED ON THE SAME
JPS55151555A (en) Proline derivatives and their production
JPS5520711A (en) New 1,3,4-thiadiazol-5-ylthiol esters and their preparation
GB1262333A (en) New hydantoins their preparation and compositions containing them
JPS5231059A (en) Preparation of oxybenzoylbenzoic acids
JPS54128584A (en) Novel 3,4-dihydrocarbostyril derivative
JPS55164671A (en) Azetidine derivative and its preparation
GB1422223A (en) Isothiocyanates
JPS52133973A (en) Preparation of optically active lactam derivatives
SE8403349L (en) HETERYCYCLIC ETHIC ACID ESTERS

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8207476-6

Effective date: 19881108

Format of ref document f/p: F