SE7606808L - Forfarande for framstellning av antracykliner och optiskt aktiva antracyklinoner - Google Patents

Forfarande for framstellning av antracykliner och optiskt aktiva antracyklinoner

Info

Publication number: SE7606808L
Authority: SE; Sweden
Prior art keywords: anthracyclines; diastereomer; alpha; procedure; manufacture
Prior art date: 1976-06-14

Application number

SE7606808A

Other languages

English (en)

Other versions

SE421318B (sv

Inventor

F Arcamone

L Bernardi

B Patelli

S Penco

Original Assignee

Farmaceutici Italia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-14

Filing date

1976-06-15

Publication date

1977-12-16

1976-06-15 Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia

1977-12-16 Publication of SE7606808L publication Critical patent/SE7606808L/sv

1981-12-14 Publication of SE421318B publication Critical patent/SE421318B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SE7606808A 1976-06-14 1976-06-15 Forfarande for framstellning av antracyklinglykosidor SE421318B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7617955A FR2355028A1 (fr)	1976-06-14	1976-06-14	Procede pour la preparation de glycosides derives d'anthracyclines optiquement actives

Publications (2)

Publication Number	Publication Date
SE7606808L true SE7606808L (sv)	1977-12-16
SE421318B SE421318B (sv)	1981-12-14

Family

ID=9174331

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SE7606808A SE421318B (sv)	1976-06-14	1976-06-15	Forfarande for framstellning av antracyklinglykosidor
SE8100471A SE447988B (sv)	1976-06-14	1981-01-26	Forfarande for uppdelning av racemiska aglykoner

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SE8100471A SE447988B (sv)	1976-06-14	1981-01-26	Forfarande for uppdelning av racemiska aglykoner

Country Status (11)

Country	Link
US (1)	US4107423A (sv)
JP (1)	JPS532463A (sv)
AT (2)	AT344899B (sv)
BE (1)	BE842930A (sv)
CA (1)	CA1046510A (sv)
CH (1)	CH622529A5 (sv)
DE (1)	DE2626783C2 (sv)
FR (1)	FR2355028A1 (sv)
GB (1)	GB1509875A (sv)
NL (2)	NL175300C (sv)
SE (2)	SE421318B (sv)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1567456A (en) *	1976-11-16	1980-05-14	Farmaceutici Italia	Daunomycin derivatives
IL55431A (en) *	1978-08-24	1982-07-30	Yeda Res & Dev	Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
NL8001417A (nl) *	1979-03-17	1980-09-19	Erba Farmitalia	Antitumorglycosiden.
GB2056443B (en) *	1979-08-20	1984-01-18	Hoffmann La Roche	Cyclic compounds
JPS56135021A (en) *	1980-03-25	1981-10-22	Nippon Kokan Kk <Nkk>	Lining for internal surface of welded part of steel pipe
CA1174669A (en) *	1980-07-18	1984-09-18	Michael J. Broadhurst	Anthracycline glycosides
GB8317037D0 (en) *	1983-06-23	1983-07-27	Erba Farmitalia	6-deoxyanthracyclines
US4540695A (en) *	1981-08-12	1985-09-10	Sumitomo Chemical Co., Ltd.	Aminonaphthacene derivatives and their use
NL8300150A (nl) *	1982-01-26	1983-08-16	Erba Farmitalia	Daunorubicine en doxorubicine-analoga, hun bereiding en toepassing.
FI75834C (sv) *	1982-05-24	1988-08-08	Erba Farmitalia	Förfarande för framställning av antracyklinglykosidföreningar
JPS59212499A (ja) *	1983-05-13	1984-12-01	アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド	抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
US4831019A (en) *	1983-10-31	1989-05-16	Adria Laboratories, Inc.	Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines
US4496485A (en) *	1983-11-25	1985-01-29	G. D. Searle & Co.	Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
NZ224252A (en)	1987-04-21	1991-09-25	Erba Carlo Spa	An anthracycline glycoside and its preparation
GB8803301D0 (en) *	1988-02-12	1988-03-09	Erba Carlo Spa	Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB9418260D0 (en) *	1994-09-09	1994-10-26	Erba Carlo Spa	Anthracycline derivatives
DE10155016A1 (de) *	2001-11-07	2003-05-15	Knoell Hans Forschung Ev	Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung
US8173621B2 (en)	2008-06-11	2012-05-08	Gilead Pharmasset Llc	Nucleoside cyclicphosphates
PA8855601A1 (es)	2008-12-23	2010-07-27		Forformidatos de nucleósidos
US8716263B2 (en)	2008-12-23	2014-05-06	Gilead Pharmasset Llc	Synthesis of purine nucleosides
US8551973B2 (en) *	2008-12-23	2013-10-08	Gilead Pharmasset Llc	Nucleoside analogs
WO2011123668A2 (en)	2010-03-31	2011-10-06	Pharmasset, Inc.	Stereoselective synthesis of phosphorus containing actives
US8846882B2 (en) *	2011-04-29	2014-09-30	Synbias Pharma Ag	Method of producing 4-demethoxydaunorubicin
CN104151376B (zh) *	2014-06-23	2017-02-08	天津药物研究院新药评价有限公司	一种抗肿瘤药物及其合成方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3427300A (en) *	1965-11-12	1969-02-11	Merck & Co Inc	Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
YU33730B (en) *	1967-04-18	1978-02-28	Farmaceutici Italia	Process for preparing a novel antibiotic substance and salts thereof
US3803124A (en) *	1968-04-12	1974-04-09	Farmaceutici It Soc	Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3629231A (en) *	1968-05-23	1971-12-21	Biorex Laboratories Ltd	Derivatives of glycyrrhetinic acid
FI51808C (sv) *	1968-07-15	1977-04-12	Rhone Poulenc Sa	Förfarande för framställning av nya antitumorala naftacenderivat.
GB1467383A (en) *	1974-06-12	1977-03-16	Farmaceutici Italia	Daunomycin analogues
US4039663A (en) *	1975-03-19	1977-08-02	Societa' Farmaceutici Italia S.P.A.	Daunomycins, process for their uses and intermediates

1976
- 1976-06-12 GB GB24439/76A patent/GB1509875A/en not_active Expired
- 1976-06-14 FR FR7617955A patent/FR2355028A1/fr active Granted
- 1976-06-14 BE BE167900A patent/BE842930A/xx not_active IP Right Cessation
- 1976-06-15 DE DE2626783A patent/DE2626783C2/de not_active Expired
- 1976-06-15 SE SE7606808A patent/SE421318B/sv active Protection Beyond IP Right Term
- 1976-06-16 CH CH769276A patent/CH622529A5/de not_active IP Right Cessation
- 1976-06-21 AT AT450676A patent/AT344899B/de active Protection Beyond IP Right Term
- 1976-06-21 AT AT636377A patent/AT345461B/de not_active IP Right Cessation
- 1976-06-24 NL NLAANVRAGE7606897,A patent/NL175300C/xx not_active IP Right Cessation
- 1976-06-25 JP JP7454176A patent/JPS532463A/ja active Granted
- 1976-06-29 CA CA255,970A patent/CA1046510A/en not_active Expired
- 1976-08-14 US US05/695,434 patent/US4107423A/en not_active Expired - Lifetime
1981
- 1981-01-26 SE SE8100471A patent/SE447988B/sv unknown
1993
- 1993-06-24 NL NL930090C patent/NL930090I2/nl unknown

Also Published As

Publication number	Publication date
NL930090I2 (nl)	1994-03-16
NL7606897A (nl)	1977-12-28
DE2626783C2 (de)	1985-08-14
CH622529A5 (en)	1981-04-15
NL930090I1 (nl)	1993-10-01
JPS532463A (en)	1978-01-11
FR2355028A1 (fr)	1978-01-13
US4107423A (en)	1978-08-15
BE842930A (fr)	1976-10-01
FR2355028B3 (sv)	1979-03-02
JPS6123200B2 (sv)	1986-06-04
ATA450676A (de)	1977-12-15
AT344899B (de)	1978-08-10
SE8100471L (sv)	1981-01-26
CA1046510A (en)	1979-01-16
SE421318B (sv)	1981-12-14
ATA636377A (de)	1978-01-15
DE2626783A1 (de)	1977-12-29
NL175300C (nl)	1984-10-16
AT345461B (de)	1978-09-25
NL175300B (nl)	1984-05-16
GB1509875A (en)	1978-05-04
SE447988B (sv)	1987-01-12

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BE854947A (fr)	1977-11-24	Nouveaux derives de l'acide 6'-amino-spiro(cycloalkane-1,2-penam)-3'-carboxylique

Legal Events

Date	Code	Title	Description
1994-06-27	SPCF	Application for supplementary protection certificate filed	Free format text: 7606808
1995-01-31	NAL	Patent in force	Ref document number: 7606808-9
1996-02-19	SPCG	Supplementary protection certificate granted	Free format text: 9490108, 910620, EXPIRES: 20010615