SE518528C2 - Ett förfarande för framställning av ett öppet poröst polymermaterial samt ett öppet poröst polymermaterial - Google Patents
Ett förfarande för framställning av ett öppet poröst polymermaterial samt ett öppet poröst polymermaterialInfo
- Publication number
- SE518528C2 SE518528C2 SE0004856A SE0004856A SE518528C2 SE 518528 C2 SE518528 C2 SE 518528C2 SE 0004856 A SE0004856 A SE 0004856A SE 0004856 A SE0004856 A SE 0004856A SE 518528 C2 SE518528 C2 SE 518528C2
- Authority
- SE
- Sweden
- Prior art keywords
- polymeric material
- porous polymeric
- porogen
- polymer
- open
- Prior art date
Links
- 239000000463 material Substances 0.000 title claims abstract description 57
- 238000000034 method Methods 0.000 title claims abstract description 40
- 229920000642 polymer Polymers 0.000 claims abstract description 61
- 239000003361 porogen Substances 0.000 claims abstract description 44
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 42
- 239000013078 crystal Substances 0.000 claims abstract description 27
- 239000000203 mixture Substances 0.000 claims abstract description 25
- 239000002904 solvent Substances 0.000 claims abstract description 13
- 239000011148 porous material Substances 0.000 claims description 12
- 210000000988 bone and bone Anatomy 0.000 claims description 9
- 239000002244 precipitate Substances 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 7
- 229920003226 polyurethane urea Polymers 0.000 claims description 7
- 229920002396 Polyurea Polymers 0.000 claims description 6
- 210000001612 chondrocyte Anatomy 0.000 claims description 6
- 229920002635 polyurethane Polymers 0.000 claims description 6
- 239000004814 polyurethane Substances 0.000 claims description 6
- OSNSWKAZFASRNG-WNFIKIDCSA-N (2s,3r,4s,5s,6r)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol;hydrate Chemical compound O.OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O OSNSWKAZFASRNG-WNFIKIDCSA-N 0.000 claims description 4
- 125000004185 ester group Chemical group 0.000 claims description 4
- 229960001031 glucose Drugs 0.000 claims description 4
- 239000007943 implant Substances 0.000 claims description 4
- 230000001376 precipitating effect Effects 0.000 claims description 4
- -1 shaped bodies Substances 0.000 claims description 4
- 238000007493 shaping process Methods 0.000 claims description 4
- HBDJFVFTHLOSDW-DNDLZOGFSA-N (2r,3r,4r,5r)-2,3,5,6-tetrahydroxy-4-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanal;hydrate Chemical compound O.O=C[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HBDJFVFTHLOSDW-DNDLZOGFSA-N 0.000 claims description 3
- 230000000735 allogeneic effect Effects 0.000 claims description 3
- 210000004204 blood vessel Anatomy 0.000 claims description 3
- 238000011049 filling Methods 0.000 claims description 3
- 239000010408 film Substances 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 3
- 239000003102 growth factor Substances 0.000 claims description 3
- 229960003017 maltose monohydrate Drugs 0.000 claims description 3
- 239000011159 matrix material Substances 0.000 claims description 3
- 150000004682 monohydrates Chemical class 0.000 claims description 3
- 210000000963 osteoblast Anatomy 0.000 claims description 3
- 210000004409 osteocyte Anatomy 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 230000008929 regeneration Effects 0.000 claims description 3
- 238000011069 regeneration method Methods 0.000 claims description 3
- 210000000130 stem cell Anatomy 0.000 claims description 3
- 210000002435 tendon Anatomy 0.000 claims description 3
- 239000000969 carrier Substances 0.000 claims description 2
- 210000004027 cell Anatomy 0.000 claims description 2
- 150000004683 dihydrates Chemical class 0.000 claims description 2
- 230000002255 enzymatic effect Effects 0.000 claims description 2
- 230000007062 hydrolysis Effects 0.000 claims description 2
- 238000006460 hydrolysis reaction Methods 0.000 claims description 2
- 239000010409 thin film Substances 0.000 claims description 2
- 210000002950 fibroblast Anatomy 0.000 claims 2
- 210000005036 nerve Anatomy 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 230000001413 cellular effect Effects 0.000 claims 1
- 239000002861 polymer material Substances 0.000 abstract description 6
- 238000001556 precipitation Methods 0.000 abstract description 3
- 239000000243 solution Substances 0.000 description 20
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 9
- 238000005266 casting Methods 0.000 description 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-L Phosphate ion(2-) Chemical compound OP([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-L 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 238000003490 calendering Methods 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000000748 compression moulding Methods 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 239000008241 heterogeneous mixture Substances 0.000 description 2
- 238000001746 injection moulding Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 229910009112 xH2O Inorganic materials 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/26—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
- C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
- C08G18/4269—Lactones
- C08G18/4277—Caprolactone and/or substituted caprolactone
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2110/00—Foam properties
- C08G2110/0041—Foam properties having specified density
- C08G2110/0058—≥50 and <150kg/m3
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2201/00—Foams characterised by the foaming process
- C08J2201/04—Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
- C08J2201/042—Elimination of an organic solid phase
- C08J2201/0422—Elimination of an organic solid phase containing oxygen atoms, e.g. saccharose
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2201/00—Foams characterised by the foaming process
- C08J2201/04—Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
- C08J2201/054—Precipitating the polymer by adding a non-solvent or a different solvent
- C08J2201/0542—Precipitating the polymer by adding a non-solvent or a different solvent from an organic solvent-based polymer composition
- C08J2201/0544—Precipitating the polymer by adding a non-solvent or a different solvent from an organic solvent-based polymer composition the non-solvent being aqueous
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2205/00—Foams characterised by their properties
- C08J2205/04—Foams characterised by their properties characterised by the foam pores
- C08J2205/05—Open cells, i.e. more than 50% of the pores are open
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2375/00—Characterised by the use of polyureas or polyurethanes; Derivatives of such polymers
- C08J2375/02—Polyureas
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Materials For Medical Uses (AREA)
- Biological Depolymerization Polymers (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004856A SE518528C2 (sv) | 2000-12-27 | 2000-12-27 | Ett förfarande för framställning av ett öppet poröst polymermaterial samt ett öppet poröst polymermaterial |
| US10/451,989 US7425288B2 (en) | 2000-12-27 | 2001-12-21 | Method for preparing an open porous polymer material and an open porous polymer material |
| PCT/SE2001/002893 WO2002051920A1 (fr) | 2000-12-27 | 2001-12-21 | Procede de preparation d'un materiau polymerique a pores ouverts et materiau polymerique a pores ouverts |
| EP01272439A EP1353982A1 (fr) | 2000-12-27 | 2001-12-21 | Procede de preparation d'un materiau polymerique a pores ouverts et materiau polymerique a pores ouverts |
| AU2002216594A AU2002216594B2 (en) | 2000-12-27 | 2001-12-21 | A method for preparing an open porous polymer material and an open porous polymer material |
| CNB01822363XA CN1322040C (zh) | 2000-12-27 | 2001-12-21 | 制备开放多孔聚合物材料的方法和开放多孔聚合物材料 |
| JP2002553405A JP2004522823A (ja) | 2000-12-27 | 2001-12-21 | 連続気泡重合体材料の製造方法及び連続気泡重合体材料 |
| ARP010106032A AR032051A1 (es) | 2000-12-27 | 2001-12-26 | Procedimiento de preparacion de un material polimerico de poros abiertos, material preparado por dicho procedimiento, mezcla que comprende un hidroxido de azucar y una solucion de polimero, material disenado que comprende dicho material polimerico de poros abiertos y su uso |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004856A SE518528C2 (sv) | 2000-12-27 | 2000-12-27 | Ett förfarande för framställning av ett öppet poröst polymermaterial samt ett öppet poröst polymermaterial |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE0004856D0 SE0004856D0 (sv) | 2000-12-27 |
| SE0004856L SE0004856L (sv) | 2002-06-28 |
| SE518528C2 true SE518528C2 (sv) | 2002-10-22 |
Family
ID=20282435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0004856A SE518528C2 (sv) | 2000-12-27 | 2000-12-27 | Ett förfarande för framställning av ett öppet poröst polymermaterial samt ett öppet poröst polymermaterial |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7425288B2 (fr) |
| EP (1) | EP1353982A1 (fr) |
| JP (1) | JP2004522823A (fr) |
| CN (1) | CN1322040C (fr) |
| AR (1) | AR032051A1 (fr) |
| AU (1) | AU2002216594B2 (fr) |
| SE (1) | SE518528C2 (fr) |
| WO (1) | WO2002051920A1 (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2258396B1 (es) * | 2005-02-01 | 2007-12-16 | Laura Santos Esteve | Nueva estructura de soporte polimerica 3d para la regeneracion de tejidos y su tecnica de preparacion. |
| CA2597092A1 (fr) * | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Formulations des gel aqueux contenant des modificateurs de reponse immunitaire |
| WO2007046746A1 (fr) * | 2005-10-21 | 2007-04-26 | Artimplant Ab | Implant osteo-cartilagineux biodegradable |
| US20080114277A1 (en) | 2006-11-09 | 2008-05-15 | Archel Ambrosio | Porous bioresorbable dressing conformable to a wound and methods of making same |
| US9296846B2 (en) | 2008-12-18 | 2016-03-29 | The Trustees Of The University Of Pennsylvania | Porous polymer coating for tooth whitening |
| WO2010114633A1 (fr) | 2009-04-03 | 2010-10-07 | Biomerix Corporation | Éléments de matrice élastomère réticulée au moins partiellement résorbables et leurs procédés de production |
| DK3441616T3 (da) * | 2009-09-22 | 2023-05-30 | Ecp Entw Mbh | Komprimerbar rotor til en fluidpumpe |
| US9138308B2 (en) | 2010-02-03 | 2015-09-22 | Apollo Endosurgery, Inc. | Mucosal tissue adhesion via textured surface |
| US9205577B2 (en) * | 2010-02-05 | 2015-12-08 | Allergan, Inc. | Porogen compositions, methods of making and uses |
| ES2623475T3 (es) | 2010-05-11 | 2017-07-11 | Allergan, Inc. | Composiciones de porógenos, métodos para hacerlas y usos |
| WO2012097381A1 (fr) | 2011-01-14 | 2012-07-19 | Biomerix Corporation | Éléments matriciels élastomères réticulés au moins partiellement résorbables et leurs procédés de fabrication |
| US9458357B2 (en) | 2011-03-02 | 2016-10-04 | Massachusetts Institute Of Technology | ph-sensitive sacrificial materials for the microfabrication of structures |
| WO2013074099A1 (fr) | 2011-11-16 | 2013-05-23 | Empire Technology Development Llc | Échafaudage cellulaire biodégradable poreux tridimensionnel |
| WO2014022657A1 (fr) | 2012-08-02 | 2014-02-06 | Allergan, Inc. | Adhésion au tissu muqueux via une surface texturée |
| US10569479B2 (en) | 2012-08-21 | 2020-02-25 | Vertera, Inc. | Systems and methods for making porous films, fibers, spheres, and other articles |
| EP2900289A1 (fr) | 2012-09-28 | 2015-08-05 | Allergan, Inc. | Compositions porogènes, procédés de fabrication et utilisations |
| US9498922B2 (en) | 2014-06-26 | 2016-11-22 | Vertera, Inc. | Apparatus and process for producing porous devices |
| US9504550B2 (en) | 2014-06-26 | 2016-11-29 | Vertera, Inc. | Porous devices and processes for producing same |
| USD815281S1 (en) | 2015-06-23 | 2018-04-10 | Vertera, Inc. | Cervical interbody fusion device |
| KR102106363B1 (ko) * | 2019-01-28 | 2020-05-06 | 한국과학기술원 | 다공성 구조물의 제조 방법 |
| JP2021003007A (ja) * | 2019-06-25 | 2021-01-14 | 株式会社日立製作所 | 多孔質体、多孔質体の製造方法、多孔質体の移植方法及び細胞担体 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1122804A (en) * | 1964-08-13 | 1968-08-07 | Porous Plastics Ltd | Improvements relating to the production of microporous polymeric plastics materials |
| DE1694181C3 (de) * | 1967-08-09 | 1975-02-06 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung mikroporöser Folien auf Polyurethanbasis |
| US3714307A (en) * | 1971-02-24 | 1973-01-30 | Kanegafuchi Spinning Co Ltd | Aqueous coagulation of salt containing polyurethane to form porous sheet |
| US4870059A (en) * | 1985-11-27 | 1989-09-26 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Dehydration of hydrous matter with anhydrous maltose |
| US5006569A (en) * | 1989-08-16 | 1991-04-09 | Pmc, Inc. | Density reduction in flexible polyurethane foams |
| CN1120560A (zh) * | 1994-10-11 | 1996-04-17 | 杨子华 | 多孔有机材料的制做方法 |
| WO1998037131A1 (fr) | 1997-02-21 | 1998-08-27 | Dsm N.V. | Article en mousse thermoelastique |
| DE19812195C2 (de) | 1998-03-19 | 2000-03-30 | Uwe Storch | Verfahren zur Herstellung eines gewebebildenden Implantats und seine Verwendung |
-
2000
- 2000-12-27 SE SE0004856A patent/SE518528C2/sv not_active IP Right Cessation
-
2001
- 2001-12-21 WO PCT/SE2001/002893 patent/WO2002051920A1/fr not_active Ceased
- 2001-12-21 JP JP2002553405A patent/JP2004522823A/ja active Pending
- 2001-12-21 US US10/451,989 patent/US7425288B2/en not_active Expired - Lifetime
- 2001-12-21 EP EP01272439A patent/EP1353982A1/fr not_active Withdrawn
- 2001-12-21 AU AU2002216594A patent/AU2002216594B2/en not_active Ceased
- 2001-12-21 CN CNB01822363XA patent/CN1322040C/zh not_active Expired - Fee Related
- 2001-12-26 AR ARP010106032A patent/AR032051A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002051920A1 (fr) | 2002-07-04 |
| EP1353982A1 (fr) | 2003-10-22 |
| AR032051A1 (es) | 2003-10-22 |
| CN1322040C (zh) | 2007-06-20 |
| CN1487966A (zh) | 2004-04-07 |
| US20040077739A1 (en) | 2004-04-22 |
| JP2004522823A (ja) | 2004-07-29 |
| SE0004856D0 (sv) | 2000-12-27 |
| US7425288B2 (en) | 2008-09-16 |
| SE0004856L (sv) | 2002-06-28 |
| AU2002216594B2 (en) | 2006-06-08 |
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