SE446595B - SELF-INFECTIVE CARPET WITH AN ALKYL PHOSPHATE INFORLIVATE IN THE BACKPROOF - Google Patents

Description

10 15 20 25 30 35 40 446 595 pe the high temperatures in the molding of plastic materials without lose their effectiveness, and which remain active for a long period of time space.

A further object of the invention is to provide keep a disinfectant that is relatively inexpensive and that does not require any special processes or procedures at the handling.

A further object of the invention is to provide a disinfectant that can be incorporated in a low percentage in highly variable plastic materials without adversely affecting work plastic material linen-dwelling properties. Yet another object of the invention is to provide a disinfectant that is effective against both gram-positive as gram-negative bacteria over a wide range of concentrations.

It is also an object of the invention to provide keep a self-disinfecting plastic material that can be molded, taken, blown, extruded or calendered. A purpose according to the invention also constitutes to provide a plastic base for carpets that make the upper surface of the carpet self-disinfecting.

It has been found that certain alkyl phosphate derivatives can disperse made into a liquid or molten plastic material and give specific fungicidal and bactericidal properties of the plastic material, and that disinfectant properties remain durable thereafter that the plastic material has been cast, calendered, shaped or otherwise method-processed by methods in plastic molding. Alkyl phosphate the derivatives can be blended into liquid polymers, such as dispersions. polyvinyl chloride (PVC), then carried out and modifying the produced polyvinyl film or coating. exhibits the unique bactericidal properties and is effective against both gram-positive and gram-negative organisms, including grasping then Pseudomonas aeruginosa. Other examples of plastic in which the alkyl phosphate derivatives of the invention can be found use consists of polyethylene, cellulose acetate butyrated, polyol veneers, polypropylenes, polystyrene, various phenolic resins and polystyrene renbutadiene. Use may also occur in epoxy materials, acrylic materials, polyvinyl acetate and other resins and polymer emulsions The amount of alkyl phosphate incorporated into the plastic mixture may vary depending on the specific use and the specific specific organism intended to be inhibited. Test results show however, that the alkyl phosphate derivative is usually sufficiently effective 15 20 3% 446 595 and when less than one% by weight of the weight of the plastic material is used turned. Additional amounts from one hundredth of a percent (0.01%) to 10 percent (10 l) how tried and how yielded effective results under special conditions.

The alkyphosphate derivatives of the present invention can be is made by the general formula wherein R represents alkyl having up to 18 carbon atoms, R1 represents alkyl or hydroxy-substituted alkyl having up to 18 carbon atoms, R 2 has the same meaning as R 1, R 3 represents alkyl of up to 18 carbon atoms, and R 4 has the same meaning as R 5. Examples of meanings for the R groups are shown in the following scheme: _3- R1 Rz _ Rs R4 -CxHZX + 1 -CH3 -CH3 -ø-CXH2x + 1 «ø-CXH2X + 1 -CXHZX-OH CXHZX-OH vari x = l-18 vari x = 1-18 vari x = 1-18 vari x = 1-18 vari x = 1-18 The most preferred alkyl phosphate derivatives have been found to be the following: wherein the preferred amount is 0.10-1% by weight, calculated on the weight of the plastic material to which it is added.

The present invention has been found to effectively inhibit the growth of both gram-positive and gram-negative organisms, and has been shown to be effective against Sarcina lutea, Staphylococcus coccus aureus, Staphylococcus ulbus, Pseudomonas aeruginosa, Escherichia coli, Klebsíella, Candida albicans, Salmonella choleraesuis, Enterobacter aerogenes, Escherichia communior, 10 15 20 ZS 30 35 40 446 595 4 Streptococcus pyogenes, Bacillus megaterium, Aspergillus niger and other.

When mixing the selected additive in a plastic material, select an appropriate amount of the disinfectant .or the additive. If, for example, 1,000 kg of polyethylene tablets resin is to be inhibited, 1 kg of the additive can be selected and added a tumbling mixer containing -polyethylene tablet- terna. During the tumbling mixing process, it forms drawn embodiment of the additive shown above an oily coating laying on the plastic tablets and adheres as a result at the tablets. After mixing for about 15 minutes, add the batch homogeneously combined with the plastic tablets of polyethylene, and the coated tablets as such can be stored or transported and no separation occurs between the additive and the tablet terna; This also constitutes a definite advantage over the previously known ones systems, where two or more additives are used to inhibit carry both gram-positive and gram-negative microorganisms, which mixing difficulties and precipitation have been shown to pose a serious inconvenience of prior art methodsLiquid polymers or polymer blends can also be used with the present invention, although the plastic tablets or beads constitute the preferred form of plastic material for use in the invention ningen.

After the polyethylene tablets as described above sufficiently mixed with the selected additive, can the tablets are then loaded into a hopper in a conventional one melt extruder, where the tablets are then melted and the disintegrated the affecting additive is homogeneously distributed throughout the melt mass by the action of the extruder. The mass obtained from plastic materials can be formed into various designs, films or objects in a conventional, käñt way. Produced in this way foils or articles contain an even dispersion of additives the agent and has a smooth and even texture.

During the heating in the melt extruder as described above, temperatures can reach ZSO ° C, although the preferred range is it is from 150-ZSOOC, but even at the higher temperatures can no loss in the effect of the disinfectant is detected.

It is often desirable to use conventional spinning nozzles. pieces together with melt extruders for the manufacture of thermoplastic fibers. The present invention is adapted for 10 15 20 25 5,446,595 use with such fiber making, and the threads and yarns which can be prepared and contains the inhibitory additive prevents the growth of both gram-positive and gram-negative organisms more on those yarns, threads and fabrics made there.

An example of the practice of the present invention is is written in the following: One tenth to 1.5 parts of the preferred embodiment (preferred alkyl phosphate derivative) of the foregoing the disinfectant is added to 10 parts of polyethylene tablets. Tab- the letters are coated with the oily additive by tumbling of the mixture for 20 minutes. The tablets thus treated were then melted in a test tube by immersing the tube in one oil bath at 200 ° C for 20 minutes. The test tube is then picked up from the oil bath and allowed to cool to room temperature, whereby it melts the mass solidifies. The cooled mass is then taken out of the test tube and sawn into slices with a thickness of about 10 mm. No down- refraction or other unusual property of the polyethylene sheets can demonstrated. The slices are placed in suitably grafted petri dishes, containing nutrient agar. The agar inoculated in this way with different organisms, an incubation period of 24 hours is given at 37 ° C with the discs present to inhibit the growth of the bacteria and fungi around the discs, whereby an inhibitory zone is formed. The following results are obtained: Table A Organism Inhibition Zone 1 mm Staph-aureus 10 Pseudomonas Aeruginosa 4 E. Coli - 6 Klebsiella 8 Candida albicans 10 Salmonella chloreasius 7 Aspergillus niger 10 Trichophyton mentagrophytes 15 It has been found to be particularly effective in producing one self-disinfecting carpet by adding the disinfectant additives to carpet substrates in its manufacture. In some 10 15 20 25 30 35 446 595 carpets used a polyvinyl chloride emulsion in the substrate, while other carpet manufacturers wish to coat the manufactured carpet with a resin material, such as styrene-butadiene or another additional composition. In either case, the disinfectant alkyl the phosphate derivative is incorporated into the substrate during its preparation and as such provide a disinfectant for carpet and the upper surface of the mat due to capillary action or attraction of the yarn at the mat surface. This capillary action or attraction significantly reduces the gram-positive or gram-negative active bacteria, including Pseudomonas aeruginosa, which comes into contact with the upper or lower surface of the carpet. If consequential a nylon mat is woven and by spraying or other means is provided with a styrene support containing alkyl phosphate the additive, the yarns or threads of nylon come in the upper of the carpet surface by capillary action to bring the additive contained in mixed in the styrene-butadiene to migrate towards the upper parts of the surface of the carpet and thereby form a carpet with disinfectant can against a wide variety of common bacteria and fungi. As indicated above, various resins were used to produce carpet mats and includes polyvinyl chloride resins, pure butadiene, polyolefins and others. To determine the inhibitory effect of the preferred the alkyl phosphate derivative of the present invention: c H on c H 'Z 4 e R 12 zs - N --_ o - P - oc n I 2 5 c H on OCZHS 2 4 In a sample of carpet on suitable test organisms, a suitable ASTM method (designation: G22-67T), which included the following essential steps: 1) A test piece was selected with the dimensions S x 5 cm, with 100 nylon mats. yarn, melt into a polyvinyl chloride backing.

Z) Test organisms were inoculated at known levels (number of cells per ml) in nutrient media, suitable for their growth. Every mat- samples were applied between layers of such inoculated agar media in petri dishes, one for each organism. A total of SO-55 ml was used agar per petri dish. 3] Samples were incubated at 35-37 ° C for 12 days. Inhibitory 10 7,446,595 the degree of organism growth was determined by the absence of terietal growth. 4) Observations of visible and physical effects on the sample the paragraph was made.

Results: a) Microbial inhibition Use organism Content in grafted $ killed by total nutrient salts, number of organisms cells / ml in the inoculum culture (mean from , two tests) ' Staphylococcus aureus 18.5 x 103 100% Escherichía coli 10.2 x 103 99 $ Bacilius megaterium 13.6 X 103 99 s Pseudomonas aeruginosa 16.3 x 103 99 $ A. niger no growth gb) Physical changes in the carpet pieces No microbial degradation of the mat pieces could be observed. veras. No discoloration was present during washing and drying the specimens at the end of the 12 day incubation period.

Various other uses and midifications appear for the person skilled in the art, and the examples shown here are not intended to limit the present invention.

Claims (3)

446 595 5 gatentkrav A self-disinfecting mat, comprising a pile and a backing coating of plastic material, characterized in that a homogeneously distributed addition of an alkyl phosphate of the formula wherein R represents alkyl having up to 18 carbon atoms, R1 and R2 denote is incorporated in the backing. hydroxy-substituted alkyl having up to 18 carbon atoms, and R 3 and R 4 represent alkyl having up to 18 carbon atoms, the alkyl phosphate being present in a content between 0.01 and 10% by weight of the backing coating. 2. A self-disinfecting mat according to claim 1, characterized in that the backing coating comprises a polyvinyl chloride emulsion or a styrene-butadiene resin. 3. A method of producing a self-disinfecting mat, comprising a surface pile and a backing, characterized in that a) in the backing is homogeneously incorporated from 0.01 to 10% by weight, based on the weight of the backing, of an alkyl phosphate of formula 112 : <4 | H, / R -_- N \ _- o - ï: o H o \ .I n, 113 _ 'J wherein R represents alkyl having up to 18 carbon atoms, R 1 and R 2 represent hydroxy to 18 carbon atoms, and R 3 and R 4 represent alkyl of up to 18 carbon atoms, b) a portion of the added alkyl phosphate is caused by capillary action to migrate from the backing to the upper part of the surface pile to inhibit the growth of microorganisms therein, and, 446 595 c) a portion of the added alkyl phosphate is retained in the backing to inhibit the growth of microorganisms thereon.