SE330955B - - Google Patents

Info

Publication number: SE330955B
Authority: SE; Sweden
Prior art keywords: weight; therapeutically active; acid; solid; amphiphilic agent
Prior art date: 1964-05-22

Application number

SE06470/65A

Other languages

English (en)

Inventor

H Klaeui

W Rehm

W Schlegel

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1964-05-22

Filing date

1965-05-18

Publication date

1970-12-07

1965-05-18 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1970-12-07 Publication of SE330955B publication Critical patent/SE330955B/xx

Links

XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 4
239000002202 Polyethylene glycol Substances 0.000 abstract 3
239000003795 chemical substances by application Substances 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
239000002245 particle Substances 0.000 abstract 3
229920001223 polyethylene glycol Polymers 0.000 abstract 3
238000002360 preparation method Methods 0.000 abstract 3
239000007787 solid Substances 0.000 abstract 3
LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
239000013543 active substance Substances 0.000 abstract 2
HJJPJSXJAXAIPN-UHFFFAOYSA-N arecoline Chemical compound COC(=O)C1=CCCN(C)C1 HJJPJSXJAXAIPN-UHFFFAOYSA-N 0.000 abstract 2
RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 abstract 2
QBPFLULOKWLNNW-UHFFFAOYSA-N chrysazin Chemical compound O=C1C2=CC=CC(O)=C2C(=O)C2=C1C=CC=C2O QBPFLULOKWLNNW-UHFFFAOYSA-N 0.000 abstract 2
235000014113 dietary fatty acids Nutrition 0.000 abstract 2
229930195729 fatty acid Natural products 0.000 abstract 2
239000000194 fatty acid Substances 0.000 abstract 2
150000004665 fatty acids Chemical class 0.000 abstract 2
VKYKSIONXSXAKP-UHFFFAOYSA-N hexamethylenetetramine Chemical compound C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 abstract 2
229910052742 iron Inorganic materials 0.000 abstract 2
239000000843 powder Substances 0.000 abstract 2
WSPOMRSOLSGNFJ-AUWJEWJLSA-N (Z)-chlorprothixene Chemical compound C1=C(Cl)C=C2C(=C/CCN(C)C)\C3=CC=CC=C3SC2=C1 WSPOMRSOLSGNFJ-AUWJEWJLSA-N 0.000 abstract 1
LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 abstract 1
OTEKOJQFKOIXMU-UHFFFAOYSA-N 1,4-bis(trichloromethyl)benzene Chemical compound ClC(Cl)(Cl)C1=CC=C(C(Cl)(Cl)Cl)C=C1 OTEKOJQFKOIXMU-UHFFFAOYSA-N 0.000 abstract 1
241001116389 Aloe Species 0.000 abstract 1
RLFWWDJHLFCNIJ-UHFFFAOYSA-N Aminoantipyrine Natural products CN1C(C)=C(N)C(=O)N1C1=CC=CC=C1 RLFWWDJHLFCNIJ-UHFFFAOYSA-N 0.000 abstract 1
RMMXTBMQSGEXHJ-UHFFFAOYSA-N Aminophenazone Chemical compound O=C1C(N(C)C)=C(C)N(C)N1C1=CC=CC=C1 RMMXTBMQSGEXHJ-UHFFFAOYSA-N 0.000 abstract 1
235000001258 Cinchona calisaya Nutrition 0.000 abstract 1
LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 abstract 1
240000003450 Mallotus philippensis Species 0.000 abstract 1
229930193140 Neomycin Natural products 0.000 abstract 1
NHUHCSRWZMLRLA-UHFFFAOYSA-N Sulfisoxazole Chemical compound CC1=NOC(NS(=O)(=O)C=2C=CC(N)=CC=2)=C1C NHUHCSRWZMLRLA-UHFFFAOYSA-N 0.000 abstract 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
235000011399 aloe vera Nutrition 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
150000007854 aminals Chemical class 0.000 abstract 1
229960000212 aminophenazone Drugs 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
229910052785 arsenic Inorganic materials 0.000 abstract 1
RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 abstract 1
229940125717 barbiturate Drugs 0.000 abstract 1
HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
229960001948 caffeine Drugs 0.000 abstract 1
VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 abstract 1
239000000969 carrier Substances 0.000 abstract 1
RNFNDJAIBTYOQL-UHFFFAOYSA-N chloral hydrate Chemical compound OC(O)C(Cl)(Cl)Cl RNFNDJAIBTYOQL-UHFFFAOYSA-N 0.000 abstract 1
229960002327 chloral hydrate Drugs 0.000 abstract 1
229960005091 chloramphenicol Drugs 0.000 abstract 1
WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 abstract 1
229960004782 chlordiazepoxide Drugs 0.000 abstract 1
ANTSCNMPPGJYLG-UHFFFAOYSA-N chlordiazepoxide Chemical compound O=N=1CC(NC)=NC2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 ANTSCNMPPGJYLG-UHFFFAOYSA-N 0.000 abstract 1
ZPEIMTDSQAKGNT-UHFFFAOYSA-N chlorpromazine Chemical compound C1=C(Cl)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 0.000 abstract 1
229960001076 chlorpromazine Drugs 0.000 abstract 1
229960001552 chlorprothixene Drugs 0.000 abstract 1
LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 abstract 1
229910017052 cobalt Inorganic materials 0.000 abstract 1
239000010941 cobalt Substances 0.000 abstract 1
GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 1
229940117173 croton oil Drugs 0.000 abstract 1
229960001577 dantron Drugs 0.000 abstract 1
AAOVKJBEBIDNHE-UHFFFAOYSA-N diazepam Chemical compound N=1CC(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 AAOVKJBEBIDNHE-UHFFFAOYSA-N 0.000 abstract 1
229960003529 diazepam Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
150000002191 fatty alcohols Chemical class 0.000 abstract 1
239000000945 filler Substances 0.000 abstract 1
235000010299 hexamethylene tetramine Nutrition 0.000 abstract 1
239000004312 hexamethylene tetramine Substances 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
239000009355 kamala Substances 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
238000002844 melting Methods 0.000 abstract 1
230000008018 melting Effects 0.000 abstract 1
150000002731 mercury compounds Chemical class 0.000 abstract 1
229960004011 methenamine Drugs 0.000 abstract 1
235000013336 milk Nutrition 0.000 abstract 1
239000008267 milk Substances 0.000 abstract 1
210000004080 milk Anatomy 0.000 abstract 1
238000002156 mixing Methods 0.000 abstract 1
229960004927 neomycin Drugs 0.000 abstract 1
229940127240 opiate Drugs 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
239000000419 plant extract Substances 0.000 abstract 1
229920000151 polyglycol Polymers 0.000 abstract 1
239000010695 polyglycol Substances 0.000 abstract 1
229960000948 quinine Drugs 0.000 abstract 1
YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 abstract 1
229960001860 salicylate Drugs 0.000 abstract 1
239000000344 soap Substances 0.000 abstract 1
238000001694 spray drying Methods 0.000 abstract 1
ZZORFUFYDOWNEF-UHFFFAOYSA-N sulfadimethoxine Chemical compound COC1=NC(OC)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ZZORFUFYDOWNEF-UHFFFAOYSA-N 0.000 abstract 1
FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 abstract 1
229940124530 sulfonamide Drugs 0.000 abstract 1
239000011782 vitamin Substances 0.000 abstract 1
229940088594 vitamin Drugs 0.000 abstract 1
229930003231 vitamin Natural products 0.000 abstract 1
235000013343 vitamin Nutrition 0.000 abstract 1
150000003722 vitamin derivatives Chemical class 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
239000000080 wetting agent Substances 0.000 abstract 1
239000011701 zinc Substances 0.000 abstract 1
229910052725 zinc Inorganic materials 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SE06470/65A 1964-05-22 1965-05-18 SE330955B (xx)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH673264		1964-05-22

Publications (1)

Publication Number	Publication Date
SE330955B true SE330955B (xx)	1970-12-07

Family

ID=4314171

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE06470/65A SE330955B (xx)	1964-05-22	1965-05-18

Country Status (10)

Country	Link
US (1)	US3466362A (xx)
BE (1)	BE664197A (xx)
BR (1)	BR6569726D0 (xx)
DE (1)	DE1467938C3 (xx)
DK (1)	DK119079B (xx)
FR (1)	FR1455118A (xx)
GB (1)	GB1055854A (xx)
IL (1)	IL23502A (xx)
NL (1)	NL6505953A (xx)
SE (1)	SE330955B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7314765A (xx) *	1972-10-31	1974-05-02
ATE5852T1 (de) *	1978-11-20	1984-02-15	American Home Products Corporation	Therapeutische zusammensetzungen mit gesteigerter bioverfuegbarkeit und verfahren zu deren herstellung.
US4344934A (en) *	1978-11-20	1982-08-17	American Home Products Corporation	Therapeutic compositions with enhanced bioavailability
FR2552992A1 (fr) *	1983-10-11	1985-04-12	Havot Alain	Composition equilibree pour stopper la chute des cheveux et la calvitie precoce
EP0443381B2 (en) *	1990-02-14	1997-10-22	Takeda Chemical Industries, Ltd.	Effervescent composition, its production and use
US6488961B1 (en)	1996-09-20	2002-12-03	Ethypharm, Inc.	Effervescent granules and methods for their preparation
US6649186B1 (en)	1996-09-20	2003-11-18	Ethypharm	Effervescent granules and methods for their preparation
US6169118B1 (en) *	1998-11-12	2001-01-02	Block Drug Company, Inc.	Flavor blend for masking unpleasant taste of zinc compounds
US7348027B2 (en) *	2005-04-08	2008-03-25	Bayer Healthcare Llc	Taste masked veterinary formulation
US8852638B2 (en)	2005-09-30	2014-10-07	Durect Corporation	Sustained release small molecule drug formulation
CA2687979C (en)	2007-05-25	2017-07-04	Tolmar Therapeutics, Inc.	Sustained delivery formulations of risperidone compounds
GB2481017B (en)	2010-06-08	2015-01-07	Rb Pharmaceuticals Ltd	Microparticle buprenorphine suspension
US9272044B2 (en)	2010-06-08	2016-03-01	Indivior Uk Limited	Injectable flowable composition buprenorphine
GB201404139D0 (en)	2014-03-10	2014-04-23	Rb Pharmaceuticals Ltd	Sustained release buprenorphine solution formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB906422A (en) *	1958-05-02	1962-09-19	Wellcome Found	Improvements in and relating to prolonged acting pharmaceutical preparations
US3096248A (en) *	1959-04-06	1963-07-02	Rexall Drug & Chemical Company	Method of making an encapsulated tablet
US3108046A (en) *	1960-11-25	1963-10-22	Smith Kline French Lab	Method of preparing high dosage sustained release tablet and product of this method
US3139383A (en) *	1961-06-26	1964-06-30	Norton Co	Encapsulated time release pellets and method for encapsulating the same
US3170836A (en) *	1962-05-24	1965-02-23	Glaxo Lab Ltd	Injectable compositions comprising a copper-containing chelate complex compound dispersed in a stabilized oil-in-water emulsion and method of using the same
US3244595A (en) *	1965-05-07	1966-04-05	Mattox And Moore Inc	Composition for administering vitamins a, d, and e

1965
- 1965-04-12 DE DE1467938A patent/DE1467938C3/de not_active Expired
- 1965-05-10 IL IL23502A patent/IL23502A/xx unknown
- 1965-05-11 NL NL6505953A patent/NL6505953A/xx unknown
- 1965-05-13 US US455582A patent/US3466362A/en not_active Expired - Lifetime
- 1965-05-18 SE SE06470/65A patent/SE330955B/xx unknown
- 1965-05-18 FR FR17361A patent/FR1455118A/fr not_active Expired
- 1965-05-19 BR BR169726/65A patent/BR6569726D0/pt unknown
- 1965-05-19 GB GB21228/65A patent/GB1055854A/en not_active Expired
- 1965-05-20 BE BE664197A patent/BE664197A/xx unknown
- 1965-05-21 DK DK258865AA patent/DK119079B/da unknown

Also Published As

Publication number	Publication date
DE1467938C3 (de)	1973-12-20
IL23502A (en)	1969-01-29
FR1455118A (fr)	1966-10-14
US3466362A (en)	1969-09-09
BE664197A (xx)	1965-11-22
DK119079B (da)	1970-11-09
DE1467938A1 (de)	1969-03-13
BR6569726D0 (pt)	1973-08-16
GB1055854A (en)	1967-01-18
DE1467938B2 (de)	1973-05-24
NL6505953A (xx)	1965-11-23

Publication	Publication Date	Title
SE330955B (xx)	1970-12-07
US2875130A (en)	1959-02-24	Method of preparing sustained release particles and the product of the method
US3929985A (en)	1975-12-30	Anhydrous candicidin foam compositions
US2854378A (en)	1958-09-30	Tetracycline suppository
GB2029441A (en)	1980-03-19	Powder aerosol composition
CA1114744A (en)	1981-12-22	Pharmaceutical compositions containing urea
US4312889A (en)	1982-01-26	Liquid carrier concentrate for pre-loaded cup
JPS62501908A (ja)	1987-07-30	薬理的組成物及びそれを含有する薬理的製剤
US3154470A (en)	1964-10-27	Stable depilatory compositions
JPH0249719A (ja)	1990-02-20	易水分散・可溶性能を有する油溶性ビタミン粉末
US3037911A (en)	1962-06-05	Chewable, palatable, vitamin b preparations
JPS6030650B2 (ja)	1985-07-17	座薬基剤組成物
US3259545A (en)	1966-07-05	Stable aluminum hydroxide gel or aluminum hydroxide-sodium zirconium lactate antiperspirant stick
CA1139221A (en)	1983-01-11	Antacid compositions
DE2354476A1 (de)	1974-05-16	Desodorans
JPS61151133A (ja)	1986-07-09	遅延放出性被覆組成物及びこれにより被覆した被覆製剤
JPS61122213A (ja)	1986-06-10	ｄｌ―６―フェニル―２，３，５，６―テトラヒドロイミダゾ〔２，１―ｂ〕チアゾールのレジネートを含むペースト状駆虫組成物
US3689678A (en)	1972-09-05	Solid bath oil composition containing a clathrate
US3398225A (en)	1968-08-20	Coated 2, 2-dichlorovinyl phosphate and polyvinyl chloride resin anthelmintic compositions
JPS5612306A (en)	1981-02-06	Novel base for external preparation
US2506636A (en)	1950-05-09	Insecticidal dusts containing 2, 2-bis (4-methoxyphenyl)-1, 1, 1-trichloroethane andprocess for making same
US3923971A (en)	1975-12-02	Antiperspirant and deodorant composition containing lamellar substances
JPS5668619A (en)	1981-06-09	Nifedipine-containing solid composition
US3639605A (en)	1972-02-01	Wax-coated and micronized acetoxymethyl benzylpenicillinate
JP2954654B2 (ja)	1999-09-27	合成樹脂用着色剤の分散剤