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SE2550323A1 - Use of an environmentally friendly emulsifier for the manufacture of agar or agarose beads - Google Patents

Use of an environmentally friendly emulsifier for the manufacture of agar or agarose beads

Info

Publication number
SE2550323A1
SE2550323A1 SE2550323A SE2550323A SE2550323A1 SE 2550323 A1 SE2550323 A1 SE 2550323A1 SE 2550323 A SE2550323 A SE 2550323A SE 2550323 A SE2550323 A SE 2550323A SE 2550323 A1 SE2550323 A1 SE 2550323A1
Authority
SE
Sweden
Prior art keywords
emulsifier
environmentally friendly
agar
agarose beads
manufacture
Prior art date
Application number
SE2550323A
Inventor
Jakob Wåhlander
Karsten Fjärstedt
Xiao Huang
Original Assignee
Bio Works Tech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Works Tech Ab filed Critical Bio Works Tech Ab
Priority to SE2550323A priority Critical patent/SE2550323A1/en
Publication of SE2550323A1 publication Critical patent/SE2550323A1/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/24Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004Sorbent size or size distribution, e.g. particle size
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/285Porous sorbents based on polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291Gel sorbents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0036Galactans; Derivatives thereof
    • C08B37/0039Agar; Agarose, i.e. D-galactose, 3,6-anhydro-D-galactose, methylated, sulfated, e.g. from the red algae Gelidium and Gracilaria; Agaropectin; Derivatives thereof, e.g. Sepharose, i.e. crosslinked agarose
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/02Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/09Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in organic liquids
    • C08J3/091Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in organic liquids characterised by the chemical constitution of the organic liquid
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/12Powdering or granulating
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/12Agar or agar-agar, i.e. mixture of agarose and agaropectin; Derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/12Agar-agar; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

The present invention relates to the use of an environmentally friendly emulsifier in a method for manufacturing agar or agarose beads, suitable for use as chromatographic resin, wherein said emulsifier comprises sulfonate and/or sulfonic acid, but does not comprise phosphorus. The advantage of the use of said emulsifier is that it is typically biodegradable under aerobic conditions and it eliminates the risk of phosphorus leaking into the environment.
SE2550323A 2025-04-03 2025-04-03 Use of an environmentally friendly emulsifier for the manufacture of agar or agarose beads SE2550323A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SE2550323A SE2550323A1 (en) 2025-04-03 2025-04-03 Use of an environmentally friendly emulsifier for the manufacture of agar or agarose beads

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE2550323A SE2550323A1 (en) 2025-04-03 2025-04-03 Use of an environmentally friendly emulsifier for the manufacture of agar or agarose beads

Publications (1)

Publication Number Publication Date
SE2550323A1 true SE2550323A1 (en) 2025-10-02

Family

ID=97446666

Family Applications (1)

Application Number Title Priority Date Filing Date
SE2550323A SE2550323A1 (en) 2025-04-03 2025-04-03 Use of an environmentally friendly emulsifier for the manufacture of agar or agarose beads

Country Status (1)

Country Link
SE (1) SE2550323A1 (en)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070212540A1 (en) * 2005-09-19 2007-09-13 Millipore Corporation Asymmetric porous adsorptive bead
US20130225701A1 (en) * 2010-07-29 2013-08-29 Emd Millipore Corporation Grafting method to improve chromatography media performance
CN103341172A (en) * 2013-05-07 2013-10-09 中国科学院过程工程研究所 Dual-hole polysaccharide microspheres, preparation method and purpose thereof
EP2619253B1 (en) * 2010-09-24 2014-07-23 Unilever PLC Highly concentrated, spherical biopolymer gel particle suspensions prepared by hipe-gelation process
US20190002613A1 (en) * 2015-12-23 2019-01-03 Lubrizol Advanced Materials, Inc. Hydrophobically modified alkali-swellable emulsion polymers
CN116903915A (en) * 2023-05-31 2023-10-20 苏州百奥吉生物科技有限公司 A kind of large pore diameter and high rigidity agarose microsphere and its preparation method
CN118287055A (en) * 2024-03-21 2024-07-05 苏州为度生物技术有限公司 Chromatography medium and preparation method and application thereof
US20240317899A1 (en) * 2021-07-15 2024-09-26 Bio-Works Sweden Ab Method for the manufacture of agar or agarose beads using natural or vegetable oil
CN119034705A (en) * 2024-10-09 2024-11-29 集美大学 Macroporous multi-core agarose gel microsphere and preparation method thereof
KR102741170B1 (en) * 2023-10-13 2024-12-10 퓨리오젠 주식회사 Porous agar or agarose bead and producing method thereof

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070212540A1 (en) * 2005-09-19 2007-09-13 Millipore Corporation Asymmetric porous adsorptive bead
US20130225701A1 (en) * 2010-07-29 2013-08-29 Emd Millipore Corporation Grafting method to improve chromatography media performance
EP2619253B1 (en) * 2010-09-24 2014-07-23 Unilever PLC Highly concentrated, spherical biopolymer gel particle suspensions prepared by hipe-gelation process
CN103341172A (en) * 2013-05-07 2013-10-09 中国科学院过程工程研究所 Dual-hole polysaccharide microspheres, preparation method and purpose thereof
US20190002613A1 (en) * 2015-12-23 2019-01-03 Lubrizol Advanced Materials, Inc. Hydrophobically modified alkali-swellable emulsion polymers
US20240317899A1 (en) * 2021-07-15 2024-09-26 Bio-Works Sweden Ab Method for the manufacture of agar or agarose beads using natural or vegetable oil
CN116903915A (en) * 2023-05-31 2023-10-20 苏州百奥吉生物科技有限公司 A kind of large pore diameter and high rigidity agarose microsphere and its preparation method
KR102741170B1 (en) * 2023-10-13 2024-12-10 퓨리오젠 주식회사 Porous agar or agarose bead and producing method thereof
CN118287055A (en) * 2024-03-21 2024-07-05 苏州为度生物技术有限公司 Chromatography medium and preparation method and application thereof
CN119034705A (en) * 2024-10-09 2024-11-29 集美大学 Macroporous multi-core agarose gel microsphere and preparation method thereof

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