SE0302923L - Boswellinkompositioner med förhöjd halt av 3-beta-acetyl-11-keto-beta-boswellinsyra ("AKBA"), industriell tillverkning och användningar därav - Google Patents

Boswellinkompositioner med förhöjd halt av 3-beta-acetyl-11-keto-beta-boswellinsyra ("AKBA"), industriell tillverkning och användningar därav

Info

Publication number: SE0302923L
Authority: SE; Sweden
Prior art keywords: beta; boswellic acid; keto; acetyl; boswellin
Prior art date: 2002-03-13

Application number

SE0302923A

Other languages

English (en)

Other versions

SE0302923D0 (sv

Inventor

Allen L Seligson

Ronald C Terry

Daniel Alexander

Milos Sovak

Original Assignee

Biophysica Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-13

Filing date

2003-11-06

Publication date

2003-12-22

2003-11-06 Application filed by Biophysica Inc filed Critical Biophysica Inc

2003-11-06 Publication of SE0302923D0 publication Critical patent/SE0302923D0/sv

2003-12-22 Publication of SE0302923L publication Critical patent/SE0302923L/sv

Links

HMMGKOVEOFBCAU-GOBAHYPASA-N (3s,4r,4ar,6ar,6bs,8ar,11r,12s,12ar,14ar,14bs)-3-acetyloxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid Chemical compound C1C[C@H](OC(C)=O)[C@](C)(C(O)=O)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@H](C)[C@H](C)[C@H]5C4=CC(=O)[C@@H]3[C@]21C HMMGKOVEOFBCAU-GOBAHYPASA-N 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
HMMGKOVEOFBCAU-BCDBGHSCSA-N 3-Acetyl-11-keto-beta-boswellic acid Chemical compound C1C[C@@H](OC(C)=O)[C@](C)(C(O)=O)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@H](C)[C@H](C)[C@H]5C4=CC(=O)[C@@H]3[C@]21C HMMGKOVEOFBCAU-BCDBGHSCSA-N 0.000 title 1
HMMGKOVEOFBCAU-UHFFFAOYSA-N AKBA Natural products C1CC(OC(C)=O)C(C)(C(O)=O)C2CCC3(C)C4(C)CCC5(C)CCC(C)C(C)C5C4=CC(=O)C3C21C HMMGKOVEOFBCAU-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
230000004071 biological effect Effects 0.000 abstract 2
YIMHGPSYDOGBPI-YZCVQEKWSA-N 11-keto-β-boswellic acid Chemical compound C1C[C@@H](O)[C@](C)(C(O)=O)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@H](C)[C@H](C)[C@H]5C4=CC(=O)[C@@H]3[C@]21C YIMHGPSYDOGBPI-YZCVQEKWSA-N 0.000 abstract 1
NBGQZFQREPIKMG-UHFFFAOYSA-N 3beta-hydroxy-beta-boswellic acid Natural products C1CC(O)C(C)(C(O)=O)C2CCC3(C)C4(C)CCC5(C)CCC(C)C(C)C5C4=CCC3C21C NBGQZFQREPIKMG-UHFFFAOYSA-N 0.000 abstract 1
NBGQZFQREPIKMG-PONOSELZSA-N Boswellic acid Chemical compound C1C[C@@H](O)[C@](C)(C(O)=O)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C NBGQZFQREPIKMG-PONOSELZSA-N 0.000 abstract 1
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
YIMHGPSYDOGBPI-UHFFFAOYSA-N beta-KBA Natural products C1CC(O)C(C)(C(O)=O)C2CCC3(C)C4(C)CCC5(C)CCC(C)C(C)C5C4=CC(=O)C3C21C YIMHGPSYDOGBPI-UHFFFAOYSA-N 0.000 abstract 1
239000000284 extract Substances 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
235000017807 phytochemicals Nutrition 0.000 abstract 1
239000000419 plant extract Substances 0.000 abstract 1
229930000223 plant secondary metabolite Natural products 0.000 abstract 1
230000002062 proliferating effect Effects 0.000 abstract 1
239000000741 silica gel Substances 0.000 abstract 1
229910002027 silica gel Inorganic materials 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Natural Medicines & Medicinal Plants (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Alternative & Traditional Medicine (AREA)
Biotechnology (AREA)
Botany (AREA)
Medical Informatics (AREA)
Microbiology (AREA)
Mycology (AREA)
Emergency Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)

SE0302923A 2002-03-13 2003-11-06 Boswellinkompositioner med förhöjd halt av 3-beta-acetyl-11-keto-beta-boswellinsyra ("AKBA"), industriell tillverkning och användningar därav SE0302923L (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US36429902P	2002-03-13	2002-03-13
PCT/US2003/007733 WO2003077860A2 (en)	2002-03-13	2003-03-12	BOSWELLIN COMPOSITIONS ENHANCED WITH 3-β-ACETYL-11-KETO-β-BOSWELLIC ACID (“AKBA”), INDUSTRIAL MANUFACTURE AND THEIR USES

Publications (2)

Publication Number	Publication Date
SE0302923D0 SE0302923D0 (sv)	2003-11-06
SE0302923L true SE0302923L (sv)	2003-12-22

Family

ID=28041898

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE0302923A SE0302923L (sv)	2002-03-13	2003-11-06	Boswellinkompositioner med förhöjd halt av 3-beta-acetyl-11-keto-beta-boswellinsyra ("AKBA"), industriell tillverkning och användningar därav

Country Status (4)

Country	Link
US (1)	US20030199581A1 (sv)
AU (1)	AU2003220240A1 (sv)
SE (1)	SE0302923L (sv)
WO (1)	WO2003077860A2 (sv)

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EP2242511A4 (en)	2008-01-23	2012-10-24	Boehringer Ingelheim Vetmed	IMMUNOGENIC COMPOSITIONS OF MYCOPLASMA HYOPNEUMONIAE PCV2, AND METHODS FOR PRODUCING SUCH COMPOSITIONS
EA025110B1 (ru) *	2008-09-15	2016-11-30	Лайла Нутрасьютикалс	Синергичные противовоспалительные композиции, содержащие экстракты boswellia serrata
AU2008240335C1 (en) *	2008-10-31	2014-10-16	Software AG-Stiftung	Method for preparing an aqueous solution containing triterpenic acid, aqueous solution containing triterpenic acid, and use thereof
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ITPD20120343A1 (it) *	2012-11-13	2014-05-14	Matteo Bevilacqua	Composto in particolare per la cura della depressione e dell'ansia
CN103897010B (zh) *	2012-12-25	2017-07-11	苏州博创园生物医药科技有限公司	一种用于治疗银屑病的组合物及制备方法
CN105658660A (zh)	2013-10-02	2016-06-08	勃林格殷格翰动物保健公司	Pcv2 orf2蛋白变体和由其组成的病毒样颗粒
CN104672293B (zh)	2013-11-30	2017-01-18	苏州博创园生物医药科技有限公司	一种五环三萜结构修饰化合物及其制备方法和应用
WO2015166462A1 (en) *	2014-04-30	2015-11-05	Al-Harrisi Ahmed	Method of purifying 3-o-acetyl-11-keto-beta-boswellic acid (akba)
JP7079551B2 (ja)	2016-10-04	2022-06-02	ニュートラマックスラボラトリーズ，インコーポレイテッド	ヒドロキシチロソールおよびボスウェリン酸を有する組成物
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2003
- 2003-03-12 AU AU2003220240A patent/AU2003220240A1/en not_active Abandoned
- 2003-03-12 WO PCT/US2003/007733 patent/WO2003077860A2/en not_active Ceased
- 2003-03-12 US US10/387,024 patent/US20030199581A1/en not_active Abandoned
- 2003-11-06 SE SE0302923A patent/SE0302923L/sv not_active Application Discontinuation

Also Published As

Publication number	Publication date
SE0302923D0 (sv)	2003-11-06
AU2003220240A1 (en)	2003-09-29
AU2003220240A8 (en)	2003-09-29
WO2003077860A3 (en)	2004-04-08
US20030199581A1 (en)	2003-10-23
WO2003077860A2 (en)	2003-09-25

Publication	Publication Date	Title
SE0302923L (sv)	2003-12-22	Boswellinkompositioner med förhöjd halt av 3-beta-acetyl-11-keto-beta-boswellinsyra ("AKBA"), industriell tillverkning och användningar därav
ATE315388T1 (de)	2006-02-15	Therapeutische kombinationen von fettsäuren
TR200901979T2 (tr)	2009-05-21	Antikolinerjik etkili bileşik ve ?-mimetikler bazında yeni ilaç bileşimleri.
ATE356113T1 (de)	2007-03-15	Probucolbernsteinsäureester zur hemmung der expression von vcam-1
DE60313597D1 (de)	2007-06-14	Topische pharmazeutische zusammensetzungen mit proanthocyanidinen, glycyrrhetinic säure und telmesteine zur behandlung von dermatitis
ATE236627T1 (de)	2003-04-15	Pharmazeutische zubereitung enhaltend eicosapentaensäure und/oder stearidonsäure
EA200400482A1 (ru)	2004-12-30	Кератиноциты, пригодные для применения в качестве биологически активной субстанции при лечении ран
DE60027376D1 (de)	2006-05-24	Zusammensetzungen, enthaltend Pinolensäure sowie deren Verwendung zur Gesundheitserhaltung
BR9913589A (pt)	2001-06-05	Composição, e, processo cosmético para reduzir ardência ou irritação induzidas pela aplicação tópica de uma composição
DE69932248D1 (de)	2006-08-17	Entzündungshemmende ascorbinsäurederivate
CN103463953A (zh)	2013-12-25	一种甲醛去除剂
DE602004017871D1 (de)	2009-01-02	Zubereitungen zur behandlung von arthritischen erscheinungen
SE9701161D0 (sv)	1997-03-27	New use I
FI862609A0 (fi)	1986-06-18	Akne motverkande produkt.
CN103463967A (zh)	2013-12-25	一种空气净化机专用甲醛清除剂
TR200002078T2 (tr)	2000-11-21	Sentetik polisakkaridler, hazırlanmaları için proses ve bunları içeren farmasötik kompozisyonlar.
EE200200337A (et)	2003-10-15	Uued ühendid ning nende kasutamine
CN103478177A (zh)	2014-01-01	一种空气消毒杀菌剂
CN103493850A (zh)	2014-01-08	一种空气净化机专用空气抗菌剂
DE69927260D1 (de)	2005-10-20	Topische pharmazeutische zusammensetzung zur behandlung von haut- oder zirkulatorischen krankheiten auf inflammatorischer, immun-, proliferativer oder degenerativer basis
ATE370742T1 (de)	2007-09-15	Petasinfreie polare petasitesextraktfraktionen und deren verwendung zur schmerzbehandlung
DK0967988T3 (da)	2002-07-29	Salve til behandling af forbrændinger og andre hudsygdomme
DE50005714D1 (de)	2004-04-22	Pharmazeutische zusammensetzung, umfassend eukalyptus- und orangenöl
BR0107763A (pt)	2002-11-12	âteres de dicarboxilato de cálcio, métodos para a sua fabricação, e tratamento de doenças vasculares e diabetes com os mesmos
FR2835429B1 (fr)	2006-02-10	Utilisation d'acide ascorbique pour renforcer la cohesion de la jonction dermo-epidermique

Legal Events

Date	Code	Title	Description
2005-11-08	NAV	Patent application has lapsed