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SE0203746D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE0203746D0
SE0203746D0 SE0203746A SE0203746A SE0203746D0 SE 0203746 D0 SE0203746 D0 SE 0203746D0 SE 0203746 A SE0203746 A SE 0203746A SE 0203746 A SE0203746 A SE 0203746A SE 0203746 D0 SE0203746 D0 SE 0203746D0
Authority
SE
Sweden
Prior art keywords
new compounds
compounds
tetrahydronaphtalenes
acromegaly
igf
Prior art date
Application number
SE0203746A
Other languages
Swedish (sv)
Inventor
Magnus Axelsson
Olle Larsson
Original Assignee
Karolinska Innovations Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karolinska Innovations Ab filed Critical Karolinska Innovations Ab
Priority to SE0203746A priority Critical patent/SE0203746D0/en
Publication of SE0203746D0 publication Critical patent/SE0203746D0/en
Priority to AU2003288857A priority patent/AU2003288857A1/en
Priority to PCT/SE2003/002010 priority patent/WO2004054996A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention refers to new compounds belonging to the group of substituted 1-phenyl-tetrahydronaphtalenes and the use thereof as inhibitors of the insulin-like growth factor-1 receptor. Said compounds can be used for treatment of IGF-1R dependent diseases, such as cancer, psoriasis, arteriosclerosis and acromegaly.
SE0203746A 2002-12-18 2002-12-18 New compounds SE0203746D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE0203746A SE0203746D0 (en) 2002-12-18 2002-12-18 New compounds
AU2003288857A AU2003288857A1 (en) 2002-12-18 2003-12-18 New substituted 1-phenyl-tetrahydronaphtalene derivatives and their use as inhibitors of igf-1 receptor
PCT/SE2003/002010 WO2004054996A1 (en) 2002-12-18 2003-12-18 New substituted 1-phenyl-tetrahydronaphtalene derivatives and their use as inhibitors of igf-1 receptor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0203746A SE0203746D0 (en) 2002-12-18 2002-12-18 New compounds

Publications (1)

Publication Number Publication Date
SE0203746D0 true SE0203746D0 (en) 2002-12-18

Family

ID=20289899

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0203746A SE0203746D0 (en) 2002-12-18 2002-12-18 New compounds

Country Status (3)

Country Link
AU (1) AU2003288857A1 (en)
SE (1) SE0203746D0 (en)
WO (1) WO2004054996A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625859B1 (en) 2000-02-16 2009-12-01 Oregon Health & Science University HER-2 binding antagonists
EP1940796A1 (en) * 2005-09-09 2008-07-09 Analytecon S.A. Isoquinolines derivatives as igf-1r inhibitors
US8044067B2 (en) * 2005-09-09 2011-10-25 Analytecon S.A. Isoquinolines as IGF-1R inhibitors
WO2009100349A1 (en) 2008-02-09 2009-08-13 The Trustees Of Columbia University In The City Of New York Analogues of (-)-picropodophyllin, synthesis and uses thereof
WO2011083391A2 (en) 2010-01-05 2011-07-14 Pfizer Inc. Biomarkers for anti-igf-ir cancer therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3584370D1 (en) * 1984-12-28 1991-11-14 Conpharm Ab USE OF PODOPHYLLOTOXIN AND ITS DERIVATIVES.
SE0102168D0 (en) * 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds

Also Published As

Publication number Publication date
AU2003288857A1 (en) 2004-07-09
WO2004054996A1 (en) 2004-07-01

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