SE0004781D0 - A screening assay for antagonists of human leukocyte receptors - Google Patents
A screening assay for antagonists of human leukocyte receptorsInfo
- Publication number
- SE0004781D0 SE0004781D0 SE0004781A SE0004781A SE0004781D0 SE 0004781 D0 SE0004781 D0 SE 0004781D0 SE 0004781 A SE0004781 A SE 0004781A SE 0004781 A SE0004781 A SE 0004781A SE 0004781 D0 SE0004781 D0 SE 0004781D0
- Authority
- SE
- Sweden
- Prior art keywords
- antagonists
- induced
- screening assay
- human leukocyte
- ligand
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title 1
- 210000000265 leukocyte Anatomy 0.000 title 1
- 238000007423 screening assay Methods 0.000 title 1
- 108091008034 costimulatory receptors Proteins 0.000 abstract 3
- 239000003446 ligand Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 210000005260 human cell Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000000903 blocking effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000004957 immunoregulator effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 230000001629 suppression Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/5052—Cells of the immune system involving B-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004781A SE0004781D0 (sv) | 2000-12-22 | 2000-12-22 | A screening assay for antagonists of human leukocyte receptors |
| PCT/SE2001/002841 WO2002052268A1 (en) | 2000-12-22 | 2001-12-20 | A screening assay for antagonists of human leukocyte receptors |
| CA002436777A CA2436777A1 (en) | 2000-12-22 | 2001-12-20 | A screening assay for antagonists of human leukocyte receptors |
| JP2002553116A JP2004516037A (ja) | 2000-12-22 | 2001-12-20 | ヒト白血球受容体アンタゴニストのスクリーニング・アッセイ |
| RU2003122348/15A RU2003122348A (ru) | 2000-12-22 | 2001-12-20 | Скрининг антагонистов рецепторов лейкоцитов человека |
| EP01272418A EP1344063A1 (en) | 2000-12-22 | 2001-12-20 | A screening assay for antagonists of human leukocyte receptors |
| CNA01821066XA CN1481504A (zh) | 2000-12-22 | 2001-12-20 | 用于人类白细胞受体拮抗剂的筛选试验方法 |
| US10/432,726 US20040106160A1 (en) | 2000-12-22 | 2001-12-20 | Screening assay for antagonists of human leukocyte receptors |
| NO20032458A NO20032458L (no) | 2000-12-22 | 2003-05-30 | Screeningsanalyse for antagonister av humane leukocytreseptorer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004781A SE0004781D0 (sv) | 2000-12-22 | 2000-12-22 | A screening assay for antagonists of human leukocyte receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0004781D0 true SE0004781D0 (sv) | 2000-12-22 |
Family
ID=20282361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0004781A SE0004781D0 (sv) | 2000-12-22 | 2000-12-22 | A screening assay for antagonists of human leukocyte receptors |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20040106160A1 (sv) |
| EP (1) | EP1344063A1 (sv) |
| JP (1) | JP2004516037A (sv) |
| CN (1) | CN1481504A (sv) |
| CA (1) | CA2436777A1 (sv) |
| NO (1) | NO20032458L (sv) |
| RU (1) | RU2003122348A (sv) |
| SE (1) | SE0004781D0 (sv) |
| WO (1) | WO2002052268A1 (sv) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113981031A (zh) * | 2021-11-01 | 2022-01-28 | 山西中医药大学 | 一种新型t细胞功能检测方法 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201104950D0 (en) * | 2011-03-24 | 2011-05-11 | Univ Birmingham | Immune assay |
| CN104977237B (zh) * | 2015-07-01 | 2018-02-23 | 北京理工大学 | 一种原位检测单个活细胞内细胞器中co2生成速率的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4535893A (en) * | 1992-06-15 | 1994-01-04 | Regents Of The University Of California, The | Screening assay for the identification of immunosuppressive drugs |
| WO1994014065A1 (en) * | 1992-12-14 | 1994-06-23 | Dana-Farber Cancer Institute, Inc. | Methods for identifying and using immunosuppressant compounds |
| DK1095277T3 (da) * | 1998-07-13 | 2003-04-22 | Cellomics Inc | System til cellebaseret screening |
| DE69920757T2 (de) * | 1998-12-28 | 2005-12-15 | 4 AZA Bioscience N.V. | Immunosuppressive wirkungen von pteridinderivaten |
| FR2788602B1 (fr) * | 1999-01-20 | 2002-06-07 | Inst Nat Sante Rech Med | Procede de criblage utile pour identifier des ligands potentiels pour un recepteur capable de s'internaliser |
| US6642249B2 (en) * | 2001-07-04 | 2003-11-04 | Active Biotech Ab | Immunomodulating compounds |
-
2000
- 2000-12-22 SE SE0004781A patent/SE0004781D0/sv unknown
-
2001
- 2001-12-20 EP EP01272418A patent/EP1344063A1/en not_active Withdrawn
- 2001-12-20 RU RU2003122348/15A patent/RU2003122348A/ru not_active Application Discontinuation
- 2001-12-20 WO PCT/SE2001/002841 patent/WO2002052268A1/en not_active Ceased
- 2001-12-20 JP JP2002553116A patent/JP2004516037A/ja not_active Withdrawn
- 2001-12-20 CN CNA01821066XA patent/CN1481504A/zh active Pending
- 2001-12-20 US US10/432,726 patent/US20040106160A1/en not_active Abandoned
- 2001-12-20 CA CA002436777A patent/CA2436777A1/en not_active Abandoned
-
2003
- 2003-05-30 NO NO20032458A patent/NO20032458L/no not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113981031A (zh) * | 2021-11-01 | 2022-01-28 | 山西中医药大学 | 一种新型t细胞功能检测方法 |
| CN113981031B (zh) * | 2021-11-01 | 2024-12-06 | 山西中医药大学 | 一种新型t细胞功能检测方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1344063A1 (en) | 2003-09-17 |
| NO20032458D0 (no) | 2003-05-30 |
| CA2436777A1 (en) | 2002-07-04 |
| RU2003122348A (ru) | 2005-01-27 |
| NO20032458L (no) | 2003-06-18 |
| CN1481504A (zh) | 2004-03-10 |
| US20040106160A1 (en) | 2004-06-03 |
| WO2002052268A1 (en) | 2002-07-04 |
| JP2004516037A (ja) | 2004-06-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0410933A (pt) | novos antagonistas do receptor p2x7 e seu uso | |
| BR0110079A (pt) | Combinação de compostos orgânicos | |
| NO960630L (no) | Heterocykler anvendelige som neurokinin antagonister | |
| BR9912975A (pt) | Composto e composições para liberação de agentes ativos, método para sua obtenção e seu uso | |
| AR002459A1 (es) | Antagonistas de vasopresina de benzacepina triciclicos, una composicion farmaceutica que los contiene, un metodo para tratar enfermedades y unprocedimiento para su preparacion. | |
| BR0007719A (pt) | Baff, agentes de bloqueio relacionados e uso dosmesmos no estìmulo e na inibição de células b e deimunoglobulinas em respostas imunológicas | |
| NO975598D0 (no) | Monoklonale ape-antistoffer som er spesifikke for primatiserte humane B7.1- og/eller B7.2-former, samt farmasöytiske sammensetninger | |
| BR9911621A (pt) | Bifenil sulfonamidas como antagonista duplos de receptor de angiotensina endotelina | |
| ES2091877T3 (es) | Uso de antagonistas de la angiotensina ii para la fabricacion de un medicamento para el tratamiento de la hiperuricemia. | |
| TR200001942T2 (tr) | Opioid agonist/antagonist kombinasyonlar | |
| WO2004058717A8 (en) | Isoquinolinone derivatives and their use as therapeutic agents | |
| DK1135153T3 (da) | Anvendelser af EPH-receptorantagonister og -agonister til behandling af vaskulære forstyrrelser | |
| HUP9603298A3 (en) | Heterocyclic compounds having tachykinin receptor antagonist activity, their preparation, and their use for the preparation of pharmaceutical compositions | |
| BRPI0415361A (pt) | antagonistas do receptor muscarìnico de acetilcolina | |
| CO5011096A1 (es) | Medicamentos que contienen antagonistas del receptor 5-ht3 para el tratamiento de la ibs | |
| FI960953A0 (sv) | Endotelinreceptorantagonister | |
| ATE226247T1 (de) | Menschliche neuronale nikotin-acetylcholin- rezeptor-verbindungen und methoden ihres einsatzes | |
| BR0007864A (pt) | Composto, e, uso de um composto | |
| BR9910144A (pt) | Antagonistas de receptores de quimiocinas e seu uso | |
| BR9909486A (pt) | Compostos calcilìticos | |
| NO20012194L (no) | CRF-reseptorantagonister og tilhörende fremgangsmåter | |
| MX9801890A (es) | Nuevos compuestos antagonistas selectivos del receptor nk3 humano, procedimiento para su obtencion y composiciones farmaceuticas que los contienen. | |
| EA200200207A1 (ru) | Применение антагонистов cgrp и ингибиторов высвобождения cgrp для устранения приливов в период менопаузы | |
| AR002157A1 (es) | Uso de una dosis inmunizante eficaz de esporozoitos o merozoitos de eimeria vivos, o una mezcla de los mismos | |
| DK1240326T3 (da) | Udlösende receptor der er involveret i naturlig cytotoxicitet medieret af humane naturlige dræberceller og antistoffer som identificerer denne receptor |