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SE0003810D0 - Novel compounds their use and preparations - Google Patents

Novel compounds their use and preparations

Info

Publication number
SE0003810D0
SE0003810D0 SE0003810A SE0003810A SE0003810D0 SE 0003810 D0 SE0003810 D0 SE 0003810D0 SE 0003810 A SE0003810 A SE 0003810A SE 0003810 A SE0003810 A SE 0003810A SE 0003810 D0 SE0003810 D0 SE 0003810D0
Authority
SE
Sweden
Prior art keywords
preparations
novel compounds
compounds
receptor
disorders
Prior art date
Application number
SE0003810A
Other languages
Swedish (sv)
Inventor
Gary Johansson
Bjoern M Nilsson
Patrizia Caldirola
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Priority to SE0003810A priority Critical patent/SE0003810D0/en
Publication of SE0003810D0 publication Critical patent/SE0003810D0/en
Priority to IL15468501A priority patent/IL154685A0/en
Priority to NZ524675A priority patent/NZ524675A/en
Priority to ZA200301693A priority patent/ZA200301693B/en
Priority to BR0114552-5A priority patent/BR0114552A/en
Priority to AU2001296193A priority patent/AU2001296193B2/en
Priority to EP01977043A priority patent/EP1326830A1/en
Priority to CNB018174078A priority patent/CN100378074C/en
Priority to AU9619301A priority patent/AU9619301A/en
Priority to JP2002536047A priority patent/JP4343527B2/en
Priority to CNA2008100742241A priority patent/CN101298433A/en
Priority to PCT/SE2001/002319 priority patent/WO2002032863A1/en
Priority to EA200300492A priority patent/EA006132B1/en
Priority to KR1020037005482A priority patent/KR100823908B1/en
Priority to HK06104346.7A priority patent/HK1084109B/en
Priority to YU30403A priority patent/YU30403A/en
Priority to MXPA03003397A priority patent/MXPA03003397A/en
Priority to PL36188701A priority patent/PL361887A1/en
Priority to CA002422717A priority patent/CA2422717A1/en
Priority to US10/037,110 priority patent/US7087750B2/en
Priority to NO20031589A priority patent/NO325259B1/en
Priority to US11/057,033 priority patent/US7524839B2/en
Priority to JP2009042453A priority patent/JP2009185031A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention provides 2, 3-, 4- or 5-substituted-N1-(benzensulfonyl)indoles compounds of the general formula (I) in which Ar, R2, R3, R4 and R5 are as defined in the specification. The said compounds have affinity for the 5-HT6 receptor and are useful for the treatment and prophylaxis of disorders relating to the said receptor, such as obesity and CNS disorders.
SE0003810A 2000-10-20 2000-10-20 Novel compounds their use and preparations SE0003810D0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
SE0003810A SE0003810D0 (en) 2000-10-20 2000-10-20 Novel compounds their use and preparations
CA002422717A CA2422717A1 (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
CNA2008100742241A CN101298433A (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
EA200300492A EA006132B1 (en) 2000-10-20 2001-10-19 2-, 3-, 4- or 5-substituted n-(1-(aryl-, heteroaryl- or arylalkyl)sulfonyl) indoles and their use in therapy
ZA200301693A ZA200301693B (en) 2000-10-20 2001-10-19 2-,3-4- or 5-substituted-N1-(benzensulfonyl)indoles and their use in therapy.
BR0114552-5A BR0114552A (en) 2000-10-20 2001-10-19 N1- (benzenesulfonyl) indoles 2-, 3-, 4-, 5- substituted and their use in therapy
AU2001296193A AU2001296193B2 (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-N1-(benzensulfonyl)indoles and their use in therapy
EP01977043A EP1326830A1 (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
CNB018174078A CN100378074C (en) 2000-10-20 2001-10-19 2-, 3-, 4-or 5-substituted N1- (phenylsulfonyl) indoles and their therapeutic use
AU9619301A AU9619301A (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
JP2002536047A JP4343527B2 (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-N1- (benzenesulfonyl) indoles and their use in therapy
IL15468501A IL154685A0 (en) 2000-10-20 2001-10-19 2-,3-,4-, or 5-substituted-n1-(benzensulfonyl) indoles and their use in therapy
PCT/SE2001/002319 WO2002032863A1 (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
NZ524675A NZ524675A (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-N1-(benzensulfonyl) indoles and their use in therapy
KR1020037005482A KR100823908B1 (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-N1- (benzenesulfonyl) indole and its therapeutic use
HK06104346.7A HK1084109B (en) 2000-10-20 2001-10-19 2-,3-,4-,or 5-substituted-n1-(benzensulfonyl) indoles and their use in therapy
YU30403A YU30403A (en) 2000-10-20 2001-10-19 2-,3-,4- or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
MXPA03003397A MXPA03003397A (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy.
PL36188701A PL361887A1 (en) 2000-10-20 2001-10-19 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
US10/037,110 US7087750B2 (en) 2000-10-20 2001-10-22 Compounds, their use and preparation
NO20031589A NO325259B1 (en) 2000-10-20 2003-04-08 Substituted N1- (benzenesulfonyl) indoles, such compounds for use in therapy, the use of such compounds and pharmaceutical preparations containing said compounds.
US11/057,033 US7524839B2 (en) 2000-10-20 2005-02-11 Compounds, their use and preparation
JP2009042453A JP2009185031A (en) 2000-10-20 2009-02-25 2-, 3-, 4- or 5-substituted-n1-(benzenesulfonyl)indole and therapeutic use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0003810A SE0003810D0 (en) 2000-10-20 2000-10-20 Novel compounds their use and preparations

Publications (1)

Publication Number Publication Date
SE0003810D0 true SE0003810D0 (en) 2000-10-20

Family

ID=20281502

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0003810A SE0003810D0 (en) 2000-10-20 2000-10-20 Novel compounds their use and preparations

Country Status (5)

Country Link
JP (2) JP4343527B2 (en)
CN (2) CN101298433A (en)
SE (1) SE0003810D0 (en)
YU (1) YU30403A (en)
ZA (1) ZA200301693B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1984351A1 (en) * 2006-02-17 2008-10-29 Memory Pharmaceuticals Corporation Compounds having 5-ht6 receptor affinity
KR101581289B1 (en) 2007-05-31 2015-12-31 세프라코 아이엔시. Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
UA100192C2 (en) * 2008-11-11 2012-11-26 УАЙТ ЭлЭлСи 1-(arylsulfonyl)-4-(piperazin-1-yl)-1h-benzimidazoles as 5-hydroxytryptamine-6 ligands
CN105367472B (en) * 2014-08-12 2020-04-21 广东东阳光药业有限公司 Indoline derivatives and their application in medicine
CN105367473B (en) * 2014-08-12 2020-02-11 广东东阳光药业有限公司 Indoline derivative and application thereof in medicine
CN111362858B (en) * 2020-03-16 2021-05-11 东莞市东阳光新药研发有限公司 Salts of aromatic heterocyclic derivatives and their uses
CN111233737B (en) * 2020-03-16 2021-05-11 东莞市东阳光新药研发有限公司 Salts of aromatic heterocyclic derivatives and their uses
CN111362859B (en) * 2020-03-16 2021-05-11 东莞市东阳光新药研发有限公司 Salts of aromatic heterocyclic derivatives and their uses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6100291A (en) * 1998-03-16 2000-08-08 Allelix Biopharmaceuticals Inc. Pyrrolidine-indole compounds having 5-HT6 affinity
US6133287A (en) * 1998-03-24 2000-10-17 Allelix Biopharmaceuticals Inc. Piperidine-indole compounds having 5-HT6 affinity
US6251893B1 (en) * 1998-06-15 2001-06-26 Nps Allelix Corp. Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity
JP2002518331A (en) * 1998-06-19 2002-06-25 イーライ・リリー・アンド・カンパニー Inhibition of serotonin reuptake

Also Published As

Publication number Publication date
CN1714077A (en) 2005-12-28
CN100378074C (en) 2008-04-02
JP2004524276A (en) 2004-08-12
ZA200301693B (en) 2004-03-01
JP4343527B2 (en) 2009-10-14
CN101298433A (en) 2008-11-05
JP2009185031A (en) 2009-08-20
YU30403A (en) 2006-03-03

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