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SE0003841D0 - A method and apparatus for penetration of lipid bilayer membranes - Google Patents

A method and apparatus for penetration of lipid bilayer membranes

Info

Publication number
SE0003841D0
SE0003841D0 SE0003841A SE0003841A SE0003841D0 SE 0003841 D0 SE0003841 D0 SE 0003841D0 SE 0003841 A SE0003841 A SE 0003841A SE 0003841 A SE0003841 A SE 0003841A SE 0003841 D0 SE0003841 D0 SE 0003841D0
Authority
SE
Sweden
Prior art keywords
container
needle
shaped object
lipid bilayer
penetration
Prior art date
Application number
SE0003841A
Other languages
English (en)
Swedish (sv)
Inventor
Daniel Chiu
Owe Orwar
Mattias Karlsson
Original Assignee
Daniel Chiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daniel Chiu filed Critical Daniel Chiu
Priority to SE0003841A priority Critical patent/SE0003841D0/xx
Publication of SE0003841D0 publication Critical patent/SE0003841D0/xx
Priority to AT01977029T priority patent/ATE435279T1/de
Priority to DE60139138T priority patent/DE60139138D1/de
Priority to JP2002536436A priority patent/JP4755388B2/ja
Priority to EP01977029A priority patent/EP1334184B1/fr
Priority to EEP200300158A priority patent/EE200300158A/xx
Priority to NZ525325A priority patent/NZ525325A/en
Priority to CA002426142A priority patent/CA2426142A1/fr
Priority to PL36091701A priority patent/PL360917A1/xx
Priority to CZ20031119A priority patent/CZ20031119A3/cs
Priority to US10/399,584 priority patent/US7393680B2/en
Priority to YU29303A priority patent/YU29303A/sh
Priority to KR10-2003-7005462A priority patent/KR20030055288A/ko
Priority to PCT/SE2001/002301 priority patent/WO2002033066A1/fr
Priority to SK438-2003A priority patent/SK4382003A3/sk
Priority to IL15523001A priority patent/IL155230A0/xx
Priority to RU2003114429/13A priority patent/RU2003114429A/ru
Priority to AU2001296179A priority patent/AU2001296179A1/en
Priority to ZA200302770A priority patent/ZA200302770B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/89Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SE0003841A 2000-10-20 2000-10-20 A method and apparatus for penetration of lipid bilayer membranes SE0003841D0 (sv)

Priority Applications (19)

Application Number Priority Date Filing Date Title
SE0003841A SE0003841D0 (sv) 2000-10-20 2000-10-20 A method and apparatus for penetration of lipid bilayer membranes
AU2001296179A AU2001296179A1 (en) 2000-10-20 2001-10-19 A combined electroporation and microinjection method for the penetration of lipid bilayer membranes
PL36091701A PL360917A1 (en) 2000-10-20 2001-10-19 A combined electroporation and microinjection method for the penetration of lipid bilayer membranes
US10/399,584 US7393680B2 (en) 2000-10-20 2001-10-19 Combined electroporation and microinjection method for the penetration of lipid bilayer membranes
JP2002536436A JP4755388B2 (ja) 2000-10-20 2001-10-19 電気穿孔法及び微量注入法を組み合わせた脂質二重膜の貫通方法
EP01977029A EP1334184B1 (fr) 2000-10-20 2001-10-19 Procede d'electroporation et de microinjection combinees pour la penetration de membranes bicouches lipidiques
EEP200300158A EE200300158A (et) 2000-10-20 2001-10-19 Meetod kahekihiliste lipiidmembraanide penetreerimiseks ning mikrosüstimise meetod, mahuti ning selle kasutamine
NZ525325A NZ525325A (en) 2000-10-20 2001-10-19 A combined electroporation and microinjection method for the penetration of lipid bilayer membranes
CA002426142A CA2426142A1 (fr) 2000-10-20 2001-10-19 Procede d'electroporation et de microinjection combinees pour la penetration de membranes bicouches lipidiques
AT01977029T ATE435279T1 (de) 2000-10-20 2001-10-19 Kombiniertes elektroporations- und mikroinjektionsverfahren zur durchdringung von membranen mit lipid-doppelschichten
CZ20031119A CZ20031119A3 (en) 2000-10-20 2001-10-19 A combined electroporation and microinjection method for the penetration of lipid bilayer membranes
DE60139138T DE60139138D1 (de) 2000-10-20 2001-10-19 Kombiniertes elektroporations- und mikroinjektionsverfahren zur durchdringung von membranen mit lipid-doppelschichten
YU29303A YU29303A (sh) 2000-10-20 2001-10-19 Kombinovani postupci elektroporacije i mikroinjektiranja za penetriranje dvoslojnih lipidnih membrana
KR10-2003-7005462A KR20030055288A (ko) 2000-10-20 2001-10-19 지질 이중층 막을 관통시키기 위한 일렉트로포레이션 및미세주입 병용법
PCT/SE2001/002301 WO2002033066A1 (fr) 2000-10-20 2001-10-19 Procede d'electroporation et de microinjection combinees pour la penetration de membranes bicouches lipidiques
SK438-2003A SK4382003A3 (en) 2000-10-20 2001-10-19 Combined electroporation and microinjection method for penetration of lipid bilayer membranes
IL15523001A IL155230A0 (en) 2000-10-20 2001-10-19 A combined electroporation and microinjection method for the penetration of lipid bilayer membranes
RU2003114429/13A RU2003114429A (ru) 2000-10-20 2001-10-19 Объединенный способ электропорообразования и микроинъекции для проникновения через липидные двухслойные мембраны
ZA200302770A ZA200302770B (en) 2000-10-20 2003-04-09 A combined electroporation and microinjection method for the penetration of lipid bilayer membranes.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0003841A SE0003841D0 (sv) 2000-10-20 2000-10-20 A method and apparatus for penetration of lipid bilayer membranes

Publications (1)

Publication Number Publication Date
SE0003841D0 true SE0003841D0 (sv) 2000-10-20

Family

ID=20281529

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0003841A SE0003841D0 (sv) 2000-10-20 2000-10-20 A method and apparatus for penetration of lipid bilayer membranes

Country Status (19)

Country Link
US (1) US7393680B2 (fr)
EP (1) EP1334184B1 (fr)
JP (1) JP4755388B2 (fr)
KR (1) KR20030055288A (fr)
AT (1) ATE435279T1 (fr)
AU (1) AU2001296179A1 (fr)
CA (1) CA2426142A1 (fr)
CZ (1) CZ20031119A3 (fr)
DE (1) DE60139138D1 (fr)
EE (1) EE200300158A (fr)
IL (1) IL155230A0 (fr)
NZ (1) NZ525325A (fr)
PL (1) PL360917A1 (fr)
RU (1) RU2003114429A (fr)
SE (1) SE0003841D0 (fr)
SK (1) SK4382003A3 (fr)
WO (1) WO2002033066A1 (fr)
YU (1) YU29303A (fr)
ZA (1) ZA200302770B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7456012B2 (en) * 1997-11-06 2008-11-25 Cellectricon Ab Method and apparatus for spatially confined electroporation
EP1448770A1 (fr) 2001-11-27 2004-08-25 Cellectricon AB Procede servant a combiner l'administration sequentielle d'un agent et l'electroporation de structures cellulaires et mise en application
EP1476536B1 (fr) * 2002-02-12 2011-07-20 Cellectricon Ab Systemes et procedes de changement rapide de l'environnement liquide autour de capteurs
US7071163B2 (en) * 2002-08-05 2006-07-04 Mirus Bio Corporation Compounds for targeting hepatocytes in vivo
WO2004036202A1 (fr) 2002-10-16 2004-04-29 Cellectricon Ab Electrodes nanometriques et pointes nanometriques pour l'enregistrement de courants transmembranaires dans plusieurs cellules
US6897069B1 (en) 2004-06-08 2005-05-24 Ambion, Inc. System and method for electroporating a sample
USRE50241E1 (en) * 2004-06-12 2024-12-24 Life Technologies Holdings PTE Ltd. Electroporation apparatus having an elongated hollow member
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
KR101084528B1 (ko) 2008-04-15 2011-11-18 인비트로겐 싱가포르 피티이. 엘티디. 전기천공 장치용 파이펫 팁
DK2681550T3 (en) * 2011-03-01 2016-09-12 Sophion Bioscience As Hand-held device for electrophysiological analysis
EP2681304B1 (fr) * 2011-03-03 2020-05-27 The Regents of The University of California Procédé de formation de motifs de cellules sur un substrat
RU2552298C2 (ru) * 2013-09-27 2015-06-10 Общество с ограниченной ответственностью "Медицинские нанотехнологии" Способ контролируемого введения веществ в микрообъекты
KR101599496B1 (ko) * 2014-04-25 2016-03-07 고려대학교 산학협력단 유전물질의 단일세포 내 정량적 전달방법
KR102428464B1 (ko) * 2014-12-28 2022-08-03 주식회사 펨토바이오메드 세포에 물질을 주입하여 세포를 변환시키는 방법
US11850595B2 (en) 2016-07-20 2023-12-26 The Royal Institution for the Advancement of ... Nanofluidic flow cell and method of loading same
US20180021781A1 (en) * 2016-07-20 2018-01-25 The Royal Institution For The Advancement Of Learning/Mcgill University Nanofluidic flow cell and method of loading same

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784737A (en) * 1986-04-18 1988-11-15 The United States Department Of Energy Electromicroinjection of particles into living cells
US5993434A (en) * 1993-04-01 1999-11-30 Genetronics, Inc. Method of treatment using electroporation mediated delivery of drugs and genes
JPH07133907A (ja) 1993-11-10 1995-05-23 Tokyo Gas Co Ltd 窒素酸化物低発生交番燃焼バ−ナ
JPH08322548A (ja) * 1995-05-31 1996-12-10 Nikon Corp 細胞操作方法および細胞操作装置
US5859327A (en) * 1995-08-22 1999-01-12 Genetronics, Inc. Electroporation-mediated molecular transfer in intact plants
US5874268A (en) * 1996-09-23 1999-02-23 Duke University Method of introducing exogenous compounds into cells by electroporation and apparatus for same
US6352535B1 (en) * 1997-09-25 2002-03-05 Nanoptics, Inc. Method and a device for electro microsurgery in a physiological liquid environment
US6241701B1 (en) * 1997-08-01 2001-06-05 Genetronics, Inc. Apparatus for electroporation mediated delivery of drugs and genes
SE9704076D0 (sv) 1997-11-06 1997-11-06 Holdingbolaget Vid Goeteborgs Method for permeabilisation of cell structures and use thereof
WO2000034434A1 (fr) 1998-12-07 2000-06-15 Acacia Biosciences, Inc. Reseaux d'electrodes multicanaux
US6713291B2 (en) * 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
US6079230A (en) * 1999-02-02 2000-06-27 Kong; Jian-Qiang Apparatus for preparing quartz micropipettes
US6300108B1 (en) 1999-07-21 2001-10-09 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes
AU2495801A (en) * 1999-12-22 2001-07-09 Innovation And Development Corporation Method and apparatus for targeting localised electroporation
US6846306B1 (en) 2000-10-10 2005-01-25 Cold Spring Harbor Laboratory Single cell electroporation
US7101703B2 (en) * 2001-03-09 2006-09-05 Cornell Research Foundation, Inc. Electrofusion microelectrode
US7127284B2 (en) 2001-06-11 2006-10-24 Mercator Medsystems, Inc. Electroporation microneedle and methods for its use
US6749792B2 (en) * 2001-07-09 2004-06-15 Lifescan, Inc. Micro-needles and methods of manufacture and use thereof

Also Published As

Publication number Publication date
IL155230A0 (en) 2003-11-23
KR20030055288A (ko) 2003-07-02
US20040029101A1 (en) 2004-02-12
WO2002033066A1 (fr) 2002-04-25
JP2004511258A (ja) 2004-04-15
EE200300158A (et) 2003-06-16
DE60139138D1 (de) 2009-08-13
SK4382003A3 (en) 2004-03-02
EP1334184B1 (fr) 2009-07-01
PL360917A1 (en) 2004-09-20
ZA200302770B (en) 2004-04-13
US7393680B2 (en) 2008-07-01
AU2001296179A1 (en) 2002-04-29
CZ20031119A3 (en) 2004-03-17
ATE435279T1 (de) 2009-07-15
CA2426142A1 (fr) 2002-04-25
JP4755388B2 (ja) 2011-08-24
YU29303A (sh) 2006-05-25
RU2003114429A (ru) 2004-12-10
NZ525325A (en) 2004-07-30
EP1334184A1 (fr) 2003-08-13

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