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RU98107654A - COMPOSITION FOR Oral Administration Against Dental Plaque Education - Google Patents

COMPOSITION FOR Oral Administration Against Dental Plaque Education

Info

Publication number
RU98107654A
RU98107654A RU98107654/14A RU98107654A RU98107654A RU 98107654 A RU98107654 A RU 98107654A RU 98107654/14 A RU98107654/14 A RU 98107654/14A RU 98107654 A RU98107654 A RU 98107654A RU 98107654 A RU98107654 A RU 98107654A
Authority
RU
Russia
Prior art keywords
composition
cycloalkyls
tert
oral administration
education
Prior art date
Application number
RU98107654/14A
Other languages
Russian (ru)
Other versions
RU2170079C2 (en
Inventor
Д.Стрингер Орум
К.Брамс Джон
Субраманиан Малати
Э.Келли Эрнст
Original Assignee
Колгейт-Палмолив Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Колгейт-Палмолив Компани filed Critical Колгейт-Палмолив Компани
Publication of RU98107654A publication Critical patent/RU98107654A/en
Application granted granted Critical
Publication of RU2170079C2 publication Critical patent/RU2170079C2/en

Links

Claims (3)

1. Композиция для перорального применения, включающая пригодный для перорального применения наполнитель и эффективное против образования зубного налета количество, по крайней мере, одного по существу нерастворимого в воде некатионного антибактериального агента (АА) формулы
Figure 00000001

где R2 является C3-6 циклоалкилом, необязательно частично или полностью замещенным C1-7 алкильными боковыми цепями или C3-6 циклоалкилами; R4 является (1) трет-бутилом или C3-8 н-алкилом, необязательно частично или полностью замещенным C3-6 циклоалкилами или C1-7 алкильными боковыми цепями, или (2) C3-6 циклоалкилами, необязательно частично или полностью замещенными C1-7 алкильными боковыми цепями или C3-6 циклоалкилами; и R3 является H или R2.1. The composition for oral administration, including suitable for oral use excipient and effective against the formation of plaque, the amount of at least one essentially water-insoluble non-cationic antibacterial agent (AA) of the formula
Figure 00000001

where R 2 is C 3-6 cycloalkyl optionally partially or fully substituted with C 1-7 alkyl side chains or C 3-6 cycloalkyls; R 4 is (1) tert-butyl or C 3-8 n-alkyl, optionally partially or fully substituted with C 3-6 cycloalkyls or C 1-7 alkyl side chains, or (2) C 3-6 cycloalkyls, optionally partially or fully substituted C 1-7 alkyl side chains or C 3-6 cycloalkyls; and R 3 is H or R 2 . 2. Композиция для перорального применения, включающая пригодный для перорального применения наполнитель и эффективное против образования зубного налета количество 2-трет-бутил-5-(4'-трет-бутилфенил)фенола. 2. An oral composition comprising an excipient suitable for oral use and an effective anti-plaque amount of 2-tert-butyl-5- (4'-tert-butylphenyl) phenol. 3. Композиция для перорального применения, включающая пригодный для перорального применения наполнитель и эффективное против образования зубного налета количество, по крайней мере, одного по существу нерастворимого в воде некатионного антибактериального агента (АА) формулы
Figure 00000002

где R10 выбирают из группы, включающей -C(CH3)3(трет-бутил), -C(CH3)2CH2CH3(1,1-диметилпропил), -C(CH3)2CH2CH2CH3(1,1-диметилбутил) и -C(CH3)2C(CH3)3(1,1,2,2-тетраметилпропил).3. An oral composition comprising an orally acceptable excipient and an anti-plaque amount of at least one substantially water-insoluble non-cationic antibacterial agent (AA) of the formula
Figure 00000002

where R 10 is selected from the group consisting of —C (CH 3 ) 3 (tert-butyl), —C (CH 3 ) 2 CH 2 CH 3 (1,1-dimethylpropyl), —C (CH 3 ) 2 CH 2 CH 2 CH 3 (1,1-dimethylbutyl) and -C (CH 3 ) 2 C (CH 3 ) 3 (1,1,2,2-tetramethylpropyl).
RU98107654/14A 1995-09-22 1996-09-18 Antibacterial composition for oral use and prevention of dental deposit formation and compound RU2170079C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US419695P 1995-09-22 1995-09-22
US60/004,196 1995-09-22

Publications (2)

Publication Number Publication Date
RU98107654A true RU98107654A (en) 2000-02-27
RU2170079C2 RU2170079C2 (en) 2001-07-10

Family

ID=21709632

Family Applications (1)

Application Number Title Priority Date Filing Date
RU98107654/14A RU2170079C2 (en) 1995-09-22 1996-09-18 Antibacterial composition for oral use and prevention of dental deposit formation and compound

Country Status (12)

Country Link
US (1) US5723500A (en)
EP (1) EP0852486A2 (en)
JP (1) JPH11511473A (en)
CN (1) CN1088579C (en)
AU (1) AU708974B2 (en)
BR (1) BR9610562A (en)
CA (1) CA2232838A1 (en)
CO (1) CO4770945A1 (en)
MX (1) MX9802188A (en)
RU (1) RU2170079C2 (en)
WO (1) WO1997010800A2 (en)
ZA (1) ZA967841B (en)

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