RU95117967A

RU95117967A - Effervescent TABLETS AND GRANULES AND METHOD FOR PREPARING THEM

Info

Publication number: RU95117967A
Application number: RU95117967/14A
Authority: RU
Inventors: Йожеф Береш; Ласло Лекс; Иштванне Барканьи
Original assignee: Береш Ресвеньтаршашаг
Priority date: 1993-03-10
Filing date: 1994-03-10
Publication date: 1998-01-10

Claims

1. An effervescent tablet or granule containing a shell substance, a basic effervescent component, an effervescent acid component, a sweetener, and macro and micronutrients and possibly vitamins as active substances, characterized in that it contains from 20 to 50 wt.% mannitol as a shell material, from 8 to 25 wt.% potassium bicarbonate as the main effervescent component, from 9 to 27 wt.% malic acid as the effervescent acid component, from 0.4 to 2.2 wt.% aspartame sweetener, as well as possibly flavoring, lubricants adhesives and other additives commonly used in the manufacture of effervescent tablets in the amounts necessary to bring the amount of components to 100%.

2. An effervescent tablet or granule according to claim 1, characterized in that it contains from 30 to 40 wt.% Mannitol from 14 to 18 wt.% Potassium hydrogen carbonate, from 15 to 21 wt.% Malic acid and from 0.6 to 1.5 wt.% Aspartame.

3. An effervescent tablet or granule according to claim 1, characterized in that it contains cations of magnesium, zinc, iron (II), copper (II), manganese (II), chromium (III) and molybdenum anions as macro- and microelements (V1) and selenium (1V).

4. An effervescent tablet or granule according to claim 1, characterized in that it contains iron ions in the form of iron sulfate heptahydrate, zinc ions in the form of zinc sulfate heptahydrate, copper ions in the form of copper sulfate pentahydrate, manganese ions in the form of sulfate monohydrate manganese, molybdenum ions in the form of ammonium heptamolybdenate tetrahydrate, selenium ions in the form of selenic acid, magnesium ions in the form of magnesium sulfate heptahydrate, and chromium ions in the form of chromium (III) chloride hexahydrate.

5. An effervescent tablet or granule according to claim 1, characterized in that it contains vitamins in the following amounts relative to the weight of the composition: 0.01 - 0.5 wt.% Vitamin B ₁ , 0.01 - 0.25 wt. % Vitamin B ₂ , 0.01-0.5 wt.% Vitamin B ₆ , 0.001 - 0.01 wt.% Vitamin B ₁₂ , 0.1 - 2 wt.% Nicotinamide, 0.01 - 0.5 wt. % Vitamin A, 0.0015 - 0.015 wt.% Vitamin D, 0.1 - 5 wt.% Vitamin C, 0.01 - O, 1 wt.% Folic Acid, 0.1 - 0.5 wt.% Pantothenic acid, 0.01 - 7 wt.% vitamin E and 0.001 - 0.01 wt.% vitamin N.

6. A method of obtaining effervescent tablets or granules, characterized in that it includes the operation of homogenization of 20 to 50 wt.% Mannitol, 8 to 25 wt.% Potassium hydrogen carbonate, 9 to 24 wt.% Malic acid 0.4 to 2.2 wt. % of aspartame, as well as macro- and microelements, vitamins and, possibly, flavoring, lubricating and other additives commonly used in the manufacture of effervescent tablets, subsequent granulation of the resulting homogenized mixture into granules ready for compression, and compression of tablets or granules of the desired size and durability.

7. The method according to p. 6, characterized in that 30 to 40 wt.% Mannitol, 14 to 18 wt.% Potassium hydrogen carbonate, 15 to 21 wt.% Malic acid and 0.6 to 1.5 wt.% Aspartame are homogenized with other pill components.