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RU95100864A - Method of riboflavin isolation from cultural fluid - Google Patents

Method of riboflavin isolation from cultural fluid

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Publication number
RU95100864A
RU95100864A RU95100864/13A RU95100864A RU95100864A RU 95100864 A RU95100864 A RU 95100864A RU 95100864/13 A RU95100864/13 A RU 95100864/13A RU 95100864 A RU95100864 A RU 95100864A RU 95100864 A RU95100864 A RU 95100864A
Authority
RU
Russia
Prior art keywords
riboflavin
isolation
solid phase
extract
crystals
Prior art date
Application number
RU95100864/13A
Other languages
Russian (ru)
Inventor
Э.М. Тер-Саркисян
Original Assignee
Э.М. Тер-Саркисян
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Э.М. Тер-Саркисян filed Critical Э.М. Тер-Саркисян
Priority to RU95100864/13A priority Critical patent/RU95100864A/en
Publication of RU95100864A publication Critical patent/RU95100864A/en

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Abstract

FIELD: biotechnology. SUBSTANCE: method involves the separation of solid phase from cultural fluid followed by extraction of solid phase containing biomass and riboflavin crystals with acid solution. Riboflavin crystals were precipitated from extract by its neutralization. EFFECT: enhanced purity of riboflavin at the first stage of primary precipitation.

Claims (1)

Изобретение относится к биотехнологии и касается выделения рибофлавина из культуральной жидкости. Цель изобретения - повышение степени чистоты рибофлавина, получаемого на этапе первичного осаждения. Сущность изобретения состоит в том, что после отделения от культуральной жидкости твердой фазы, содержащей биомассу продуцента и кристаллы рибофлавина, твердую фазу экстрагируют раствором кислоты и осаждают из экстракта кристаллы рибофлавина в процессе нейтрализации экстракта.The invention relates to biotechnology and for the isolation of riboflavin from the culture fluid. The purpose of the invention is to increase the purity of riboflavin obtained in the primary precipitation step. The essence of the invention is that after separation of the solid phase from the culture fluid containing the producer biomass and riboflavin crystals, the solid phase is extracted with an acid solution and riboflavin crystals are precipitated from the extract in the process of neutralizing the extract.
RU95100864/13A 1995-01-20 1995-01-20 Method of riboflavin isolation from cultural fluid RU95100864A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU95100864/13A RU95100864A (en) 1995-01-20 1995-01-20 Method of riboflavin isolation from cultural fluid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU95100864/13A RU95100864A (en) 1995-01-20 1995-01-20 Method of riboflavin isolation from cultural fluid

Publications (1)

Publication Number Publication Date
RU95100864A true RU95100864A (en) 1996-07-10

Family

ID=48450434

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95100864/13A RU95100864A (en) 1995-01-20 1995-01-20 Method of riboflavin isolation from cultural fluid

Country Status (1)

Country Link
RU (1) RU95100864A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004046347A1 (en) * 2002-11-15 2004-06-03 State Research Institute Of Genetics And Selection Of Industrial Microorganisms Method for producing riboflavin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004046347A1 (en) * 2002-11-15 2004-06-03 State Research Institute Of Genetics And Selection Of Industrial Microorganisms Method for producing riboflavin

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