RU93052408A - ACYLAMINO-ALKYLIDENE-HYDROXY-BIS-PHOSPHONE ACIDS, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION - Google Patents
ACYLAMINO-ALKYLIDENE-HYDROXY-BIS-PHOSPHONE ACIDS, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONInfo
- Publication number
- RU93052408A RU93052408A RU93052408/04A RU93052408A RU93052408A RU 93052408 A RU93052408 A RU 93052408A RU 93052408/04 A RU93052408/04 A RU 93052408/04A RU 93052408 A RU93052408 A RU 93052408A RU 93052408 A RU93052408 A RU 93052408A
- Authority
- RU
- Russia
- Prior art keywords
- acylamino
- alkylidene
- bis
- hydroxy
- production
- Prior art date
Links
- 239000002253 acid Substances 0.000 title claims 2
- 150000007513 acids Chemical class 0.000 title claims 2
- 238000000034 method Methods 0.000 title claims 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000011861 anti-inflammatory therapy Methods 0.000 claims 1
Claims (1)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITM191A000254 | 1991-02-01 | ||
| ITMI910254A IT1244698B (en) | 1991-02-01 | 1991-02-01 | ARYL-OR ARYLALKYL-ACYL AMINO-ALCHYL-HYDROXYPHOSPHONIC ACIDS, PROCEDURE FOR THEIR PREPARATION AND USE IN OSTEO-ARTICULAR THERAPY AND CONNECTIVE TISSUES IN GENERAL |
| PCT/EP1992/000102 WO1992013864A1 (en) | 1991-02-01 | 1992-01-20 | Acylamino-alkyliden-hydroxy-bisphosphonic acids useful in the therapy of osteoarticular diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93052408A true RU93052408A (en) | 1996-07-20 |
| RU2079505C1 RU2079505C1 (en) | 1997-05-20 |
Family
ID=11358376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU9293052408A RU2079505C1 (en) | 1991-02-01 | 1992-01-20 | N-acylamino-1-hydroxyalkylidene-1,1-bis-phosphonic acids and method of their synthesis |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5466682A (en) |
| EP (1) | EP0569411B1 (en) |
| JP (1) | JP3046624B2 (en) |
| KR (1) | KR100190911B1 (en) |
| AT (1) | ATE120464T1 (en) |
| AU (1) | AU653780B2 (en) |
| CA (1) | CA2101548C (en) |
| CZ (1) | CZ288731B6 (en) |
| DE (1) | DE69201863T2 (en) |
| DK (1) | DK0569411T3 (en) |
| ES (1) | ES2069990T3 (en) |
| FI (1) | FI105403B (en) |
| HK (1) | HK1006311A1 (en) |
| HU (2) | HU215918B (en) |
| IT (1) | IT1244698B (en) |
| MX (1) | MX9200452A (en) |
| PT (1) | PT100075B (en) |
| RU (1) | RU2079505C1 (en) |
| SK (1) | SK280053B6 (en) |
| WO (1) | WO1992013864A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5719303A (en) * | 1993-03-08 | 1998-02-17 | Eisai Co., Ltd. | Phosphonic acid derivatives |
| WO1998039342A1 (en) | 1997-03-07 | 1998-09-11 | Metabasis Therapeutics, Inc. | Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase |
| AU6452098A (en) | 1997-03-07 | 1998-09-22 | Metabasis Therapeutics, Inc. | Novel purine inhibitors of fructose-1,6-bisphosphatase |
| GB9710521D0 (en) * | 1997-05-22 | 1997-07-16 | Boots Co Plc | Process |
| HUP0300227A2 (en) * | 2003-01-28 | 2004-09-28 | Richter Gedeon Vegyészeti Gyár Rt. | Process for preparing 2-substituted-1-hidroxyetylidene-1,1-bisphosphonic acids and their salts with high purity |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2530139C3 (en) * | 1975-04-30 | 1979-06-21 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | N-acyl-1-aminoalkane-1,1-diphosphonic acids, their preparation and use |
| DE2651904C2 (en) * | 1976-11-13 | 1983-01-05 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | Process for the preparation of N-acyl-N-alkylaminomethanediphosphonic acids |
| DE3203308A1 (en) * | 1982-01-27 | 1983-07-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | DIPHOSPHONIC ACID DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
| EP0084822B1 (en) * | 1982-01-27 | 1986-01-08 | Schering Aktiengesellschaft | Diphosphonic acid derivatives and pharmaceutical preparations containing them |
| FR2531088B1 (en) * | 1982-07-29 | 1987-08-28 | Sanofi Sa | ANTI-INFLAMMATORY PRODUCTS DERIVED FROM METHYLENEDIPHOSPHONIC ACID AND THEIR PREPARATION METHOD |
| DE3512536A1 (en) * | 1985-04-06 | 1986-10-16 | Boehringer Mannheim Gmbh, 6800 Mannheim | NEW DIPHOSPHONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
| EP0243173B1 (en) * | 1986-04-24 | 1991-06-26 | Fujisawa Pharmaceutical Co., Ltd. | New diphosphonic acid compounds, processes for the preparation thereof and pharmaceutical composition comprising the same |
| DE3623397A1 (en) * | 1986-07-11 | 1988-01-14 | Boehringer Mannheim Gmbh | NEW DIPHOSPHONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
| JPH0778024B2 (en) * | 1988-10-14 | 1995-08-23 | 藤沢薬品工業株式会社 | Pharmaceutical preparation containing a conjugate of a pharmaceutical compound and a diphosphonic acid derivative |
| PH26923A (en) * | 1989-03-08 | 1992-12-03 | Ciba Geigy | N-substituted amino alkanediphosphonic acids |
| US5159108A (en) * | 1990-09-18 | 1992-10-27 | Merck & Co., Inc. | Process for preparing an antihypercalcemic agent |
-
1991
- 1991-02-01 IT ITMI910254A patent/IT1244698B/en active IP Right Grant
-
1992
- 1992-01-20 JP JP4503474A patent/JP3046624B2/en not_active Expired - Fee Related
- 1992-01-20 CA CA002101548A patent/CA2101548C/en not_active Expired - Fee Related
- 1992-01-20 RU RU9293052408A patent/RU2079505C1/en active
- 1992-01-20 DK DK92903398.3T patent/DK0569411T3/en active
- 1992-01-20 US US08/094,160 patent/US5466682A/en not_active Expired - Lifetime
- 1992-01-20 KR KR1019930702242A patent/KR100190911B1/en not_active Expired - Fee Related
- 1992-01-20 WO PCT/EP1992/000102 patent/WO1992013864A1/en not_active Ceased
- 1992-01-20 AU AU11709/92A patent/AU653780B2/en not_active Ceased
- 1992-01-20 HU HU9302188A patent/HU215918B/en not_active IP Right Cessation
- 1992-01-20 EP EP92903398A patent/EP0569411B1/en not_active Expired - Lifetime
- 1992-01-20 DE DE69201863T patent/DE69201863T2/en not_active Expired - Fee Related
- 1992-01-20 ES ES92903398T patent/ES2069990T3/en not_active Expired - Lifetime
- 1992-01-20 SK SK799-93A patent/SK280053B6/en unknown
- 1992-01-20 AT AT92903398T patent/ATE120464T1/en not_active IP Right Cessation
- 1992-01-20 CZ CZ19931533A patent/CZ288731B6/en not_active IP Right Cessation
- 1992-01-30 PT PT100075A patent/PT100075B/en not_active IP Right Cessation
- 1992-01-31 MX MX9200452A patent/MX9200452A/en unknown
-
1993
- 1993-07-16 FI FI933231A patent/FI105403B/en active
-
1995
- 1995-06-02 HU HU95P/P00154P patent/HU211203A9/en unknown
-
1998
- 1998-06-16 HK HK98105383A patent/HK1006311A1/en not_active IP Right Cessation
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