RU93048332A - Состав на основе гексадецилфосфохолина, способ его получения, лекарственное средство - Google Patents
Состав на основе гексадецилфосфохолина, способ его получения, лекарственное средствоInfo
- Publication number
- RU93048332A RU93048332A RU93048332/14A RU93048332A RU93048332A RU 93048332 A RU93048332 A RU 93048332A RU 93048332/14 A RU93048332/14 A RU 93048332/14A RU 93048332 A RU93048332 A RU 93048332A RU 93048332 A RU93048332 A RU 93048332A
- Authority
- RU
- Russia
- Prior art keywords
- hexadecylphosphocholine
- production
- composition based
- medicinal product
- medicinal
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title 1
- PQLXHQMOHUQAKB-UHFFFAOYSA-N miltefosine Chemical compound CCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C PQLXHQMOHUQAKB-UHFFFAOYSA-N 0.000 title 1
- 229960003775 miltefosine Drugs 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- GPLRAVKSCUXZTP-UHFFFAOYSA-N diglycerol Chemical class OCC(O)COCC(O)CO GPLRAVKSCUXZTP-UHFFFAOYSA-N 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000000087 stabilizing effect Effects 0.000 claims 1
Claims (1)
- Растворы алкилфосфохолинов в глицериналкиловых эфирах можно получить стабильными при хранении путем стабилизации величины рН в пределах 4 - 6 и без консервантов и антиоксидантов.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4235911A DE4235911A1 (de) | 1992-10-23 | 1992-10-23 | Stabilisierte Hexadecylphosphocholinlösungen in Glycerinalkylethern |
| DEP4235911.2 | 1992-10-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93048332A true RU93048332A (ru) | 1996-11-10 |
| RU2114624C1 RU2114624C1 (ru) | 1998-07-10 |
Family
ID=6471239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU93048332A RU2114624C1 (ru) | 1992-10-23 | 1993-10-22 | Состав на основе гексадецилфосфохолина, способ его получения и лекарственное средство |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5446033A (ru) |
| EP (1) | EP0593897B1 (ru) |
| JP (1) | JPH06227987A (ru) |
| CN (1) | CN1052878C (ru) |
| AT (1) | ATE136784T1 (ru) |
| CA (1) | CA2109053C (ru) |
| DE (2) | DE4235911A1 (ru) |
| DK (1) | DK0593897T3 (ru) |
| EG (1) | EG20234A (ru) |
| ES (1) | ES2086168T3 (ru) |
| GR (1) | GR3020045T3 (ru) |
| RU (1) | RU2114624C1 (ru) |
| SG (1) | SG48779A1 (ru) |
| UA (1) | UA27099C2 (ru) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6828415B2 (en) | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
| FR2729050A1 (fr) * | 1995-02-23 | 1996-07-12 | Oreal | Compositions resistant a la degradation microbienne |
| US6278004B1 (en) | 1996-11-06 | 2001-08-21 | Aventis Pharma Deutschland Gmbh | Stabilized phospholipidic composition |
| DE10028638A1 (de) | 2000-06-09 | 2001-12-20 | Schuelke & Mayr Gmbh | Lagerstabile Zusammensetzungen von Glycerinmonoalkylethern |
| US7041302B2 (en) | 2001-01-09 | 2006-05-09 | Biother Corporation | Therapeutic modulation of the tumor inflammatory response |
| DE10313272A1 (de) * | 2003-03-24 | 2004-10-21 | Baxter Healthcare S.A. | Verwendung von Miltefosine zur Behandlung von aktinischer oder multiplen aktinischer Keratosen |
| CA2767460A1 (en) * | 2009-07-09 | 2011-01-13 | Expergen Drug Development Gmbh | Liquid pharmaceutical form of alkylphosphocholine and method of preparing same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5008294A (en) * | 1985-02-11 | 1991-04-16 | Chemex Pharmaceuticals, Inc. | Methods of treating tumors with compositions of catecholic butanes |
| DE3343530A1 (de) * | 1983-12-01 | 1985-06-13 | Max Planck Gesellschaft | Arzneimittel mit verbesserter penetration der gewebsmembran |
| IE59778B1 (en) * | 1985-12-04 | 1994-04-06 | Max Planck Gesellschaft | Medicament with anti-tumour action containing hexadecylphosphocholine |
| EP0419998A3 (en) * | 1989-09-27 | 1991-10-23 | Asta Pharma Aktiengesellschaft | Use of alkylphosphonic acid derivatives for the treatment of psoriasis |
-
1992
- 1992-10-23 DE DE4235911A patent/DE4235911A1/de not_active Withdrawn
-
1993
- 1993-09-13 DE DE59302251T patent/DE59302251D1/de not_active Expired - Lifetime
- 1993-09-13 DK DK93114672.4T patent/DK0593897T3/da active
- 1993-09-13 EP EP93114672A patent/EP0593897B1/de not_active Expired - Lifetime
- 1993-09-13 SG SG1996001594A patent/SG48779A1/en unknown
- 1993-09-13 AT AT93114672T patent/ATE136784T1/de active
- 1993-09-13 ES ES93114672T patent/ES2086168T3/es not_active Expired - Lifetime
- 1993-10-19 EG EG66893A patent/EG20234A/xx active
- 1993-10-19 US US08/137,964 patent/US5446033A/en not_active Expired - Lifetime
- 1993-10-20 CN CN93119330A patent/CN1052878C/zh not_active Expired - Lifetime
- 1993-10-21 JP JP5263455A patent/JPH06227987A/ja active Pending
- 1993-10-21 UA UA93002241A patent/UA27099C2/ru unknown
- 1993-10-22 RU RU93048332A patent/RU2114624C1/ru active
- 1993-10-22 CA CA002109053A patent/CA2109053C/en not_active Expired - Fee Related
-
1996
- 1996-05-27 GR GR960401408T patent/GR3020045T3/el unknown
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