[go: up one dir, main page]

RU93005057A - PHARMACEUTICAL COMPOUNDS, THYENOBENZODIAZEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION, PHARMOCOMPOSITION AND THEIR USE - Google Patents

PHARMACEUTICAL COMPOUNDS, THYENOBENZODIAZEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION, PHARMOCOMPOSITION AND THEIR USE

Info

Publication number
RU93005057A
RU93005057A RU93005057/04A RU93005057A RU93005057A RU 93005057 A RU93005057 A RU 93005057A RU 93005057/04 A RU93005057/04 A RU 93005057/04A RU 93005057 A RU93005057 A RU 93005057A RU 93005057 A RU93005057 A RU 93005057A
Authority
RU
Russia
Prior art keywords
thyenobenzodiazepine
pharmocomposition
pharmaceutical compounds
derivatives
production
Prior art date
Application number
RU93005057/04A
Other languages
Russian (ru)
Other versions
RU2125574C1 (en
Inventor
Фейрхерст Джон
Майкл Хоттен Терренс
Эдвард Таппер Дэвид
Original Assignee
Лилли Индастриз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929211379A external-priority patent/GB9211379D0/en
Priority claimed from GB939309025A external-priority patent/GB9309025D0/en
Application filed by Лилли Индастриз Лимитед filed Critical Лилли Индастриз Лимитед
Publication of RU93005057A publication Critical patent/RU93005057A/en
Application granted granted Critical
Publication of RU2125574C1 publication Critical patent/RU2125574C1/en

Links

Claims (1)

Предложены фармацевтические соединения формулы
Figure 00000001

в которой R1 обозначает водород или галоген, R2 обозначает C1 - 1 0алкил, C2 - 1 0алкенил, C2 - 1 0 алкинил, C3 - 6 циклоалкил,
необязательно замещенный от 1 до 3 C1 - 4алкильными группами, C3 - 6 циклоалкил C1 - 4алкил, в котором циклоалкильная группа необязательно замещена от 1 до 3 C1 - 4 алкильными группами, или необязательно замещенный фенил C1 - 4 алкил, или их соли.The proposed pharmaceutical compounds of the formula
Figure 00000001

in which R 1 denotes hydrogen or halogen, R 2 denotes C 1 - 1 0 alkyl, C 2 - 1 0 alkenyl, C 2 - 1 0 alkynyl, C 3 - 6 cycloalkyl,
optionally substituted with 1 to 3 C 1 - 4 alkyl groups, C 3 - 6 cycloalkyl, C 1 - 4 alkyl in which the cycloalkyl group is optionally substituted with 1 to 3 C 1 - 4 alkyl groups, or optionally substituted phenyl C 1 - 4 alkyl , or their salts.
RU93005057A 1992-05-29 1993-05-28 Thienobenzodiazepines or pharmaceutically acceptable salts thereof, process for preparing thereof, and pharmaceutical composition RU2125574C1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB929211379A GB9211379D0 (en) 1992-05-29 1992-05-29 Pharmaceutical compounds
GB9211379.4 1992-05-29
GB9309025.6 1993-04-30
GB939309025A GB9309025D0 (en) 1993-04-30 1993-04-30 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
RU93005057A true RU93005057A (en) 1996-02-27
RU2125574C1 RU2125574C1 (en) 1999-01-27

Family

ID=26300951

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93005057A RU2125574C1 (en) 1992-05-29 1993-05-28 Thienobenzodiazepines or pharmaceutically acceptable salts thereof, process for preparing thereof, and pharmaceutical composition

Country Status (21)

Country Link
EP (1) EP0582368B1 (en)
JP (1) JP3219541B2 (en)
CN (1) CN1043994C (en)
AT (1) ATE198891T1 (en)
AU (1) AU668159B2 (en)
CA (1) CA2097016A1 (en)
CZ (1) CZ282783B6 (en)
DE (1) DE69329887T2 (en)
DK (1) DK0582368T3 (en)
ES (1) ES2153373T3 (en)
FI (1) FI101538B1 (en)
GR (1) GR3035587T3 (en)
HU (1) HU218278B (en)
IL (1) IL105827A (en)
MX (1) MX9303124A (en)
MY (1) MY109943A (en)
NO (1) NO305125B1 (en)
NZ (1) NZ247703A (en)
PT (1) PT582368E (en)
RU (1) RU2125574C1 (en)
TW (1) TW268005B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457101A (en) * 1994-06-03 1995-10-10 Eli Lilly And Company Thieno[1,5]benzoidiazepine use
US5574028A (en) * 1994-10-31 1996-11-12 Eli Lilly And Company Method for treating anxiety
CR5278A (en) * 1995-03-24 1996-07-04 Lilly Co Eli ORAL FORMULATION OF 2-METHYL-THENO-BENZODIACEPINE
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
US5891461A (en) * 1995-09-14 1999-04-06 Cygnus, Inc. Transdermal administration of olanzapine
BR9708246A (en) * 1996-03-25 1999-07-27 Lilly Co Eli Method for treating pain
UA44838C2 (en) * 1996-03-25 2002-03-15 Елі Ліллі Енд Компані METHOD OF TREATMENT OF MIGRAINE
CZ296263B6 (en) * 1996-03-25 2006-02-15 Eli Lilly And Company Pharmaceutical composition for treating pain and use thereof
ZA978515B (en) * 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
AU720366B2 (en) * 1996-09-23 2000-06-01 Eli Lilly And Company Olanzapine dihydrate D
TR199900651T2 (en) * 1996-09-24 1999-07-21 Eli Lilly And Company Kaplanm�� par�ac�k form�lasyonu.
RU2185383C1 (en) * 2001-05-22 2002-07-20 Институт молекулярной генетики РАН 2-methyl-4-(4-methyl-1-piperazinyl)-10h-thieno-[2,3-b][1,5]benzodiazepine high-labeled with tritium
JP6270845B2 (en) 2012-08-21 2018-01-31 ヤンセン ファーマシューティカ エヌ．ベー． Antibodies against aripiprazole and uses thereof
PL2888257T3 (en) 2012-08-21 2018-02-28 Janssen Pharmaceutica Nv Haptens of quetiapine for use in immunoassays
PT2888284T (en) 2012-08-21 2022-11-18 Janssen Pharmaceutica Nv Antibodies to risperidone haptens and use thereof
PT3321254T (en) 2012-08-21 2020-10-20 Janssen Pharmaceutica Nv Haptens of aripiprazole and their use in immunoassays
PL2888258T3 (en) 2012-08-21 2019-10-31 Janssen Pharmaceutica Nv Haptens of paliperidone
PL2888592T3 (en) 2012-08-21 2018-03-30 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
CA2882489A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc. Antibodies to paliperidone haptens and use thereof
CN110054694B (en) 2012-08-21 2024-02-20 詹森药业有限公司 Antibodies to aripiprazole hapten and uses thereof
PL2888263T3 (en) 2012-08-21 2018-10-31 Janssen Pharmaceutica Nv Haptens of risperidone and paliperidone
WO2014031662A2 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to olanzapine and use thereof
CA2882595C (en) 2012-08-21 2019-06-04 Ortho-Clinical Diagnostics, Inc. Antibodies to olanzapine haptens and use thereof
ES2701062T3 (en) * 2012-08-21 2019-02-20 Janssen Pharmaceutica Nv Olanzapine Haptens
PT2888593T (en) 2012-08-21 2018-12-12 Janssen Pharmaceutica Nv Antibodies to risperidone and use thereof
CN104736564B (en) 2012-08-21 2019-02-05 詹森药业有限公司 Antibodies to quetiapine hapten and uses thereof
EP2888277A4 (en) 2012-08-21 2016-05-18 Ortho Clinical Diagnostics Inc Antibodies to paliperidone and use thereof
JP6994461B2 (en) 2015-12-17 2022-02-04 ヤンセン ファーマシューティカ エヌ．ベー． Antibodies to quetiapine and their use
WO2017106501A1 (en) 2015-12-17 2017-06-22 Janssen Pharmaceutica Nv Antibodies to risperidone and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH569730A5 (en) * 1972-04-04 1975-11-28 Wander Ag Dr A
US3962248A (en) * 1972-04-04 1976-06-08 Sandoz, Inc. Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
SU629879A3 (en) * 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Method of obtaining thieno(1,5)-benzodiazepines or salts thereof
US4061752A (en) * 1975-08-06 1977-12-06 Sandoz Ltd. 6-Piperazino-11-methylene-dibenzazepines[b,e]
FI762646A7 (en) * 1975-09-24 1977-03-25 Sandoz Ag
CH624682A5 (en) * 1976-11-10 1981-08-14 Sandoz Ag
US4761411A (en) * 1983-05-18 1988-08-02 Hoechst-Roussel Pharmaceuticals Inc. Dihydrobenzopyrrolobenzodiazepines useful for treating pyschoses
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds

Similar Documents

Publication Publication Date Title
RU93005057A (en) PHARMACEUTICAL COMPOUNDS, THYENOBENZODIAZEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION, PHARMOCOMPOSITION AND THEIR USE
RU92004593A (en) HETEROCYCLYLMETHYL-CHROMAN DERIVATIVES IN THE FORM OF A MIXTURE OF ISOMERS OR SEPARATE ISOMERS OR THEIR SALTS, METHOD FOR PRODUCING THEM AND MEDICINE
RU93055137A (en) HETEROCYCLO-CYCLIC DERIVATIVES OF AMINES, METHOD OF OBTAINING, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT
RU93004417A (en) NEW ARYL CYCLOALKYL DERIVATIVES, METHODS FOR THEIR PRODUCTION AND USE
NL300396I1 (en) Novel derivatives with naphthalene structures, process for their preparation and the pharmaceutical preparations containing them
RU93004577A (en) Derivatives of imidazole with a side chain of biphenylsulfonylurea
RU95115522A (en) CONNECTION SUITABLE FOR THE TREATMENT OF CNS DISEASES, PHARMACEUTICAL COMPOSITION
DE3670081D1 (en) IMIDAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL COMPILATIONS.
KR890011596A (en) Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for treating insomnia
DE3686979D1 (en) CEPHEM CONNECTIONS AND METHOD FOR THEIR PRODUCTION.
DE69330601D1 (en) SEROTON INERGIC ERGOLIN DERIVATIVES
ES529069A0 (en) PROCEDURE FOR PREPARING NEW DERIVATIVES OF INERT SALTS OF AMINOPYRIDINE HYDROXIDE AND ITS CORRESPONDING SALTS
DE3778642D1 (en) THERAPEUTIC FOR TREATMENT OF STOMACH.
ES536218A0 (en) PROCEDURE FOR OBTAINING HYDROXIETILAZOLYLOXIME DERIVATIVES
DE3861271D1 (en) BASICLY SUBSTITUTED BENZOFURANCARBONIC ACID AMIDES, PROCESS FOR THEIR PRODUCTION AND THERAPEUTIC AGENTS CONTAINING THE SAME.
RU92016209A (en) Benzofuranylimidazole derivatives, method for their production and therapeutic compositions containing derivatives
RU93033697A (en) DERIVATIVES 2-AMINO-N - [[[4- (AMINOCARBONIL) PYRIMIDIN-2-IL] AMINO] ALKYL] PYRIMIDIN-4-CARBOXAMIDE, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION
PT78155A (en) N- (3-TRIFLUOROMETHYLPHENYL) -N'-PROPARGYLPIPERAZINE ITS PREPARATION AND ITS USE
SE8006142L (en) 1,2,4-triazole-3-thiols
SE8402361L (en) NEW ACYLAMINOPHENOLD DERIVATIVES
HUT42280A (en) Fungicidal compositions and process for preparing piperazinyl-methyl-1,2,4-triazolyl-methyl-carbinol derivatives applicable as active substance
KR900012884A (en) (+) 1-[(3,4,5-trimethoxy) -benzyloxymethyl] -1-phenyl-N, N-dimethyl-n-propylamine, preparation method thereof and therapeutic use
RU93043526A (en) INDENOINDAL COMPOUNDS, METHOD OF THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION, ANTI-OXIDATIVE COMPOSITION, METHOD OF STABILIZATION
ATE82289T1 (en) 1-HYDROXYALKYLXANTHINS, PROCESS FOR THEIR PRODUCTION AND MEDICATIONS CONTAINING THEM.
FI911616A0 (en) SUBSTITUTES 3-TIA-ELLER 3-OXA-ALKYL-FLAVONER, FOER FARAND FOR DERASE FRAMSTAELLNING, DERAS ANVAENDNING, PAO DESSA FOERENINGAR BASERADE FOR CEILINGS SAMT MELLANPRODUKTER.