RU2730889C2 - Method for fasting course for critically ill patients - Google Patents

Abstract

FIELD: medicine.SUBSTANCE: invention discloses a method for fasting course for severely ill patients. Described is a method for starvation, in which food and fluids are excluded, and before the start of the starvation course from 5 to 10 days, a vegetarian diet with dietary meals is adhered to, representing a vegetable diet or a vegetable diet in combination with porridges freshly prepared from whole grains of cereals. Fasting begins after emptying. Starvation course includes the main cycle having unseparated consecutive initial, main and final stages. Initial stage is 1–3 days apart food and fluid excluding water and urine. Main stage is performed for not less than 11 days with complete exclusion of food and fluid. Final stage is 1–3 days apart food and fluid excluding water and urine. Main stage of the main fasting cycle is followed by rinsing the oral cavity. Method comprises taking in patient's live E.coli and E.coli lactose-negative sticks strains and growing their cultures under artificial conditions, providing their storage during whole period of starvation, then, during the vegetarian diet after the final stage of starvation, grown cultures of typical and lactose-negative E.coli rods are taken. patient's strain. After the first emptying of the intestine, the patient is analyzed and the level of E.coli rods is checked for compliance with the norms, where normality is as follows: typical E.coli rods 10–10 CFU/g of faeces, E.coli lactose-negative <10 CFU/g of faeces, E.coli hemolytic—0. In case of deviation from norm if level of E.coli sticks is insufficient, repeated typical and/or lactose-negative E.coli rods are repeated. patient's strain, and if level of E.coli rods is excessive, the corresponding foodstuffs and/or lactose-negative E.coli rods are excluded in the next meal. If E.coli haemolytic rods are found, oral rehydration is prescribed, in which the patient should drink up to 3 liters of liquid a day.EFFECT: technical result is reduction of pain in patients, easier transfer of starvation rate.9 cl, 7 ex

Description

The invention relates to medicine and can be used for critically ill patients undergoing a course of fasting in order to reduce their pain.

A modern man, exposed to more than 4,000 chemicals, often leads an unnatural lifestyle, accompanied by elements of unhealthy diet. In combination with other influences, this often leads to disruption of self-regulation of the human body, changes in consciousness and the emergence of various serious diseases, including cancer. According to the International Union Against Cancer (1982), the induction phase of cancer lasts 15-20 years, the in situ phase - 5-10 years, the invasion phase - 1-5 years, the dissemination phase - 1-5 years. It has been proven that in the in situ phase, reversible changes in a malignant reborn mutant cell are possible with the help of immune mechanisms. It follows from this that each person has only 15-20 years for planned work in the framework of primary and secondary prevention of cancer.

Another threat today is infectious diseases such as hepatitis, tuberculosis, AIDS, as well as severe somatic diseases such as prostatitis, myocarditis, etc.

The search for opportunities to restore the impaired self-regulation of the human body has become more relevant than ever, since many of the existing effective methods for eliminating the symptoms of certain diseases do not contribute to the patient's health as a whole.

A known method for the treatment of oncological diseases, including the introduction into the patient's body of decoctions of herbal medicines and the patient's medical fasting (RU, patent for invention No. 2074731, A61K 35/78, published 03/10/1997 [1]).

The known method is carried out as follows: throughout the day, with a gradual increase in dosage, a tincture of the fruiting bodies of the red fly agaric, the tincture of the root of Dzhungarian aconite, the tincture of the herb hemlock spotted and then the decoction of collection 1 containing the herb of celandine, pink catharanthus and mistletoe, are introduced, then a decoction of the collection is introduced 2, containing yarrow herb, marigold flowers and dandelion root, as well as tincture of echination, powder of Pallas milkweed root and alcoholic tincture of garlic, then a decoction of collection 3 containing the root of thick-leaved bergenia is introduced, the herb St. John's wort and flowers of fireweed are introduced tincture of propolis with honey, periodically during the day, infusion of chaga is injected, and during the course of treatment, therapeutic fasting is periodically carried out in combination with breathing exercises, cold procedures, cleaning of the gastrointestinal tract. Fasting is carried out once every 1-2 weeks for two days.

The disadvantage of this method is the use in the treatment of toxic and allergenic substances, which limits the use of this method for a number of patients. The method is not universal, and, as a result of the use of toxic substances, it is quite dangerous.

A known method of rehabilitation of the human body, including fasting and dietary nutrition, including at the stages of entry and exit from it, known from the patent of the Russian Federation No. 2028160, C1 (RU, patent for invention No. 2028160, C1, IPC ⁶ A61M 21/00 , published 09.02.1995 [2]). In the known method, the essence of the method is explained in advance by the method of rational psychotherapy and the possibility of cure is suggested, then food and liquids are completely excluded within 7-11 days. At the same time, the daily biorhythm of sleep is changed to wakefulness in such a way that at night the patient is awake, exercises physical activity and takes cold water-air procedures. Sleep for the patient is organized in the morning and evening hours of the day, and during the day they create conditions for quiet wakefulness, limit spoken language and exclude sudden movements.

The known method allows you to cleanse the body of incomplete metabolic products, update the immunological status of the body, increase the body's resistance, exclude drug treatment.

However, the known method is rather difficult to tolerate by patients through a feeling of unbearable thirst, the occurrence of significant pain, especially in patients with cancer, which makes it unacceptable for a wide range of seriously ill patients and does not allow to achieve a renewal of the immune status of the human body. In addition, the known method is quite inconvenient due to the need to change the daily biorhythm of a person, which has a negative effect on the health of patients.

In general, the negative factor of this method is associated with the fact that to transfer a full course of abstinence from food and liquids for up to 11 days and change the cycle of biotrims to a night mode of wakefulness, when the patient also carries out physical activity and takes cold water-air procedures - physically impossible or very difficult, since the change of biotrims leads to a large loss of moisture in the body. Severe dehydration sets in, which carries a high risk of patient death. In this state, the patient is not able to lead an active lifestyle and perform any work, but can only lead a recumbent lifestyle.

The closest analogue is the method of rehabilitation of the human body (RU 2015106540, publ .: 20.09.2016), which includes a course of fasting and dietary nutrition at the stages of entry and exit from it, characterized in that a vegetarian diet is used as a dietary food, and the fasting course includes the main cycle, which has undivided sequential initial, main and final stages, and the initial stage is carried out for 1 day with the exclusion of food and liquid, except for water and urine, the main stage is carried out for at least 11 days with the complete exclusion of food and liquid, and the final stage is carried out for 1 day with the exclusion of food and liquid, except for water and urine, and at the main stage of the main fasting cycle, rinsing of the oral cavity is performed. The fasting course additionally includes at least one additional fasting cycle, which is carried out before the main fasting cycle or before another additional fasting cycle, while the additional fasting cycle is separated from the main cycle or from another additional fasting cycle by a vegetarian diet with a diet, and each an additional fasting cycle has undivided sequential initial, main and final stages, and the initial stage is spent 1 day with the exclusion of food and liquid, except for water and urine, the main stage is spent less than 11 days with the complete exclusion of food and liquid, and the final stage is carried out for 1 day with with the exception of food and liquid, except for water and urine, and at the main stage of each additional fasting cycle, rinse the mouth.

The decision (RU 2015106540, publ .: 09/20/2016) was taken as a prototype.

The beneficial effects of fasting are due to the known effects of fasting on the brain, whereby cognitive function is improved, neurotrophic factors are increased, resistance to stress is improved, and inflammatory processes are attenuated and reduced. Fasting is a challenge for the brain, and the brain accepts this challenge by adapting how it responds to stress, which helps further manage stress and reduces the likelihood of illness.

For example, fasting increases resistance to age-related diseases. In Parkinson's disease, intermittent abstinence from food preserves dopaminergic neurons and reduces disease progression. In Alzheimer's, fasting prevents the build-up of misfolded proteins. In Huntington's disease, fasting normalizes levels of brain-derived neurotrophic factor, which slows neuronal degeneration (Matson et al., 2008; Duan et al. 2003b). Following a fast once or twice a week will help protect the brain from degenerative diseases such as Parkinson's and Alzheimer's, according to a study by the National Institute on Aging in Baltimore, USA. Fasting combats neuronal pathology by increasing the level of proteins that prevent the accumulation of misfolded proteins, which is a hallmark of Alzheimer's and Parkinson's (Rubinsztein et al., 2011).

Fasting also increases energy production by protecting mitochondria from aging-related damage (Liu et al., 2006).

Research (Willette et al., 2012) has shown that fasting improves memory, decision making, and emotional control by preserving the volumes of brain structures involved in these processes, including the hippocampus, tonsils, and the prefrontal cortex.

In addition, fasting increases neurogenesis and stimulating trophic factors such as BDNF, insulin-like growth factor 1, and vascular endothelial growth factor cells (Lee et al., 2002; Cheng et al., 2003; Joseph D'Ercole et al., 2003; Joseph D'Ercole et al., 2008; et al. Trejo et al. 2008).

In studies (Harvey et al., 2011), fasting reduced inflammatory markers such as pro-inflammatory cytokines in the blood.

Fasting also increases blood flow and functional connections in important regions of the brain, including the hippocampus and the anterior cingulate cortex (Burdett et al., 2010), increases neural connections by increasing electrical and synaptic activity (Voss et al., 2010), and prevents neuronal death by induction of factors transcriptions, which are responsible for the expression of genes involved in the regulation of cell survival (Mattson, 2008).

Fasting slows down the cellular feature of aging, expressed by the accumulation of reactive oxygen species, which is manifested in the positive regulation of enzymes that suppress oxidative stress (Hyun et al., 2006), preserves DNA integrity by weakening the age-related decline in DNA repair, the APE1 enzyme (Kisby et al., 2010 ), stimulates autophagy in neurons, which improves the removal of damaged proteins and dead cell fragments (Alirezaei et al., 2010).

Thus, the valuable effect of fasting is evident in the cessation of inflammation and pain in critically ill people, such as cancer patients.

Experimentally, the applicant found that during the main course of fasting, consisting of three undivided stages: the initial stage for a period of 1-3 days with the exclusion of food and liquid except for water and urine, the main stage for a period of 11 or more days with the complete exclusion of food and liquid, and the final stage for a period of 1-3 days with the exclusion of food and liquids except water and urine, and rinsing the mouth during the main stage of fasting, - a decrease in the feeling of thirst is achieved, due to this, pain in patients is reduced.

In addition, as patients feel hungry and thirsty, the pain associated with various diseases is dulled. The pain becomes bearable and patients can perform some types of work while fasting.

In the case of oncological diseases, pain from the tumor is dulled due to the fact that the growth of the tumor stops due to a lack of glucose and fluid in the patient's blood, and the excitation of the nervous system associated with the tumor and causing pain is suppressed by nerve impulses coming from the digestive system. mainly from the stomach, experiencing hunger and thirst. Thus, the branching of pain sensations helps to dull the activity of each of them. Those. on the one hand, fasting helps to reduce pain from the disease, and on the other hand, the pain associated with the disease reduces the discomfort from hunger and thirst and makes them easier to endure.

As a result, the human immune status is updated for a wide range of patients. The method proposed in RU 2015106540 has a positive effect on the processes of blood circulation and respiration of human skin, and helps to reduce excess weight.

In this connection, the method disclosed in the prototype for the rehabilitation of the human body (RU 2015106540), including a course of fasting and dietary nutrition at the stages of entry and exit from it, essentially implements all the above-described positive reactions to the human body.

But at the same time, the prototype method also has unrealized measures that always accompany seriously ill people, such as cancer patients. We are talking about severe pain present in critically ill patients.

Naturally, in the process of fasting, the use of any means of anesthesia is excluded, since during fasting, painkillers can lead to poisoning and impaired liver function.

Consequently, the technical problem of the prototype method is that it does not effectively solve the problem of relieving pain. As a result, critically ill patients are sometimes unable to tolerate fasting due to unbearable pain.

The object of the invention is to eliminate the technical problem of the prototype.

The technical result is to reduce pain in patients, the ability to more easily transfer the course of fasting.

The specified technical result is achieved due to the fact that the claimed method of fasting for seriously ill patients, in which food and liquids are excluded for several days, and before the beginning of the fasting course for 5 to 10 days, they adhere to a vegetarian diet with a diet that is a vegetable diet or a vegetable diet combined with cereals freshly made from whole grains; fasting begins after emptying, the fasting course includes the main cycle, which has undivided sequential initial, main and final stages, moreover, the initial stage is carried out for 1-3 days with the exclusion of food and liquid, except for water and urine, the main stage is carried out for at least 11 days with a complete the exclusion of food and liquid, and the final stage is carried out for 1-3 days with the exclusion of food and liquid, except for water and urine, and, at the main stage of the main fasting cycle, rinsing of the mouth is carried out, characterized in that live strains of E. coli typical and lactose-negative E. coli and grow their cultures in artificial conditions, ensure their storage during the entire fasting period, then during the periods of the patient's feeding, the grown cultures of typical and lactose-negative E. Colli sticks are taken. the patient's strain; after the first bowel movement, the patient is tested and the level of E. coli bacilli is checked for compliance with the norms, where the norm is considered: typical E. coli sticks 10 ⁷ - 10 ⁸ CFU / g Feces, E. coli lactose negative <10 ⁵ CFU / g Feces , E. coli hemolytic - 0; and in case of a deviation from the norm in case of insufficient level of E. coli sticks, the corresponding typical and / or lactose-negative E. Colli sticks, the patient's strain, are repeated, and if the level of E. coli sticks is excessive, the corresponding typical and / or lactose-negative coli sticks; in case of detection of E.coli hemolytic sticks, oral rehydration is prescribed, in which the patient must drink at least 3 liters of fluid per day.

It is admitted that at the end of fasting, a vegetarian diet is used as a dietary food for 10 days, with a dietary food that is a vegetable diet or a vegetable diet in combination with cereals freshly made from whole grains of cereals, and for patients with signs of dystrophy, a vegetarian diet with dietary food is carried out until 14 days.

It is permissible that potassium-rich foods are taken.

It is acceptable that during meals between fasting courses, they take kaogsil for three weeks in an amount of 250 g.

It is admitted that the main stage of the main fasting cycle is spent 22 days.

It is admitted that the fasting course additionally includes at least one additional fasting cycle, which is separated from the main cycle or from another additional fasting cycle by a vegetarian diet with a diet, and each additional fasting cycle has undivided consecutive initial, main and final stages, and , the initial stage is carried out 1-3 days with the exclusion of food and liquid, except for water and urine, the main stage is carried out less than 11 days with the complete exclusion of food and liquid, and the final stage is carried out for 1-3 days with the exclusion of food and liquid, except for water and urine , and at the main stage of each additional fasting cycle rinsing the mouth is performed.

It is possible that rinsing the mouth during fasting is carried out with water or light drinks.

It is acceptable that the duration of a vegetarian diet with dietary food between two additional fasting cycles or between an additional fasting cycle and the main fasting cycle is from one to 10 days, while the duration of a vegetarian diet with dietary food between two additional fasting cycles is equal to the duration of the main fasting phase of the previous additional fasting cycle.

It is admitted that after a course of fasting against the background of dietary nutrition, white clay is taken.

Implementation of the invention

According to the Industry standard 91500.11.0004-2003 "Protocol for the management of patients. Intestinal dysbacteriosis", APPROVED by order of the Ministry of Health of Russia dated 09.06.2003, No. 231, the qualitative and quantitative composition of the main microflora of the large intestine in healthy people should contain E. coli typical 10 ⁷ - 10 ⁸ CFU / g Feces, E. coli lactose-negative <10 ⁵ CFU / g Feces, E. coli hemolytic - 0.

Deviations from the indicated values are a sign of dysbiosis:

- a decrease in typical Escherichia coli to 10 ⁵ -10 ⁶ CFU / g, or an increase in the content of typical Escherichia to 10 ⁹ -10 ¹⁰ ; CFU / g is defined as the first degree of microbiological disorders;

- an increase in the concentration of hemolytic Escherichia coli up to 10 ⁵ -10 ⁷ CFU / g is defined as the second degree of microbiological disorders.

E. coli E. coli are the main competitors of opportunistic microflora in terms of colonization of the intestine. E. coli E. coli take oxygen from the intestinal lumen, which is harmful to bifidobacteria and lactobacilli useful to humans. E. coli E. coli produce a number of vitamins necessary for humans: B1, B2, B3, B5, B6, biotin, B9, B12, K, fatty acids (acetic, formic, and a number of strains also lactic, succinic and others), participates in metabolism of cholesterol, bilirubin, choline, bile acids, affects the absorption of iron and calcium.

In normal conditions, healthy patients with only dysbiosis, with excessive growth of E. coli, are recommended to take bacteriophages (depending on the type of E. coli): bacteriophage coli liquid, bacteriophage coliprotein liquid, pyobacteriophage combined liquid, pyopolyphage in tablets, pyobacteriophage liquid polyvalent intereterate purified bacteriophage is liquid.

However, in states of starvation of seriously ill people, for example, in cancer patients, in order to reduce their pain, these traditional methods are not applicable for a number of reasons.

The state of starvation itself causes severe discomfort in the entire intestine, associated with strong gas formation during periods of nutrition due to dysbiosis developed during starvation, caused by the death of bacteria that regulate the number of E. coli without food in the intestinal tract.

This state of discomfort exacerbates the already strong pain sensations of critically ill patients.

The claimed invention makes it possible to reduce the level of pain during fasting courses and to endure them more easily.

The methodology of the claimed invention is based on the regulation of the number of E. coli in critically ill patients.

For this, live strains of typical E.coli and lactose-negative E.coli bacilli are taken from the patient's fecal feces or urine and their cultures are grown in artificial conditions.

Stool is collected in a preservative, which can be used as a phosphate-buffered or glycerin mixture. In the case of delivery of the material within 2 hours from the moment of collection, the native feces are collected in sterile vials. Urine after the toilet of the external genital organs is collected in a sterile container. Before sowing, urine is centrifuged and the sediment is seeded. In the case of a small amount of sediment, the native urine is inoculated into a double concentration enrichment medium in equal volumes.

If there is an insignificant amount of the pathogen in the samples and it is impossible to isolate it by the classical method, as well as to obtain a quick result, it is possible to determine E. coli directly from feces.

The detection of E. coli in the feces of patients is as reliable as the isolation of a microorganism. The main advantages of this method are the speed of determination (since isolation of pure cultures is not required) and the ability to determine their concentration at different stages of the disease.

The level of typical, lactose-negative and hemolytic E. coli is determined by bacteriological laboratories.

The grown strains of E.coli typical and E.coli lactose-negative sticks are stored during the entire fasting period, then during the patient's feeding periods, the grown cultures of typical and lactose-negative E.Colli sticks, the patient's strain, are taken.

After the first bowel movement, the patient is tested and the level of E. coli bacilli is checked for compliance with the norms, where the norm is considered: typical E. coli bacilli 10 ⁷ -10 ⁸ CFU / g Feces, E. coli lactose negative <10 ⁵ CFU / g Feces , E. coli hemolytic - 0; and in case of a deviation from the norm in case of insufficient level of E. coli bacilli, re-intake of the corresponding typical and / or lactose-negative E. Colli bacilli, the patient's strain, and in case of an excess of the level of E. coli sticks, the next meal excludes the corresponding typical and / or lactose-negative coli sticks; in case of detection of E. coli hemolytic sticks, oral rehydration is prescribed, in which the patient must drink at least 3 liters of fluid per day.

An important feature is the use of typical E.coli and lactose-negative E.coli strains when taking the patient himself, since the use of dosage forms of E.coli strains can lead to uncontrolled growth of typical and lactose-negative E.coli other strains, the growth of which is not able to control, especially with dysbiosis.

This is due to the fact that many pathogenicity factors are known: adhesion and colonization, invasions, exotoxins in pathogenic E. coli, hemolysins, Shiga toxin (STX), L toxin (heat-labile toxin), ST toxin (thermostable toxin), CNF (cytotoxic necrotic factor), CLTD-toxin, EAST toxin, endotoxins-lipopolysaccharides.

The pathogenicity factors of E. coli are controlled not only by the chromosomal genes of the host cell, but also by genes introduced by plasmids or mild converting phages. All this indicates the possibility of the emergence of pathogenic variants of E. coli as a result of the spread of plasmids and temperate phages among them. For a starving person, pathogenicity factors increase.

As a result, for patients undergoing a course of fasting there is a high risk of excessive excess of the norm for typical and lactose-negative E. coli, and so much that the identification of hemolytic bacilli E. coli was noted. As a result, the patient is forced to stop the fasting course and start taking the fluoroquinolone group.

It has been experimentally established that the use of typical E.coli and lactose-negative E.coli strains of the patient himself only in rare cases leads to an increase in the number of E.coli in excess of the norm, and that is insignificant. This insignificance is such that it was quite sufficient to exclude the intake of the corresponding typical and / or lactose-negative E.coli sticks in the next meal in order to equalize the number of E.coli to the norm. And when the norm was exceeded, the growth of E.coli hemolytic rods was so insignificant that it was not required to leave the fasting course. The appointment of oral rehydration turned out to be sufficient, in which the patient must drink at least 3 liters of fluid per day. This helped to restore the water-salt balance and compensate for the loss of fluid in the body. For oral rehydration, you can use any rehydration medication that comes in powder form for solution preparation.

The implementation of the method of rehabilitation of the human body begins with the transition of a person to a vegetarian diet with dietary nutrition, the basic principles of which are to exclude food of animal origin and obtain proteins, enzymes, vitamins, minerals and amino acids from plant or lacto-vegetarian food. Specifically, it is a vegetable diet or a vegetable diet combined with cereals freshly made from whole grains. This diet should be followed for 5-10 days. After physiological cleaning (emptying), a fasting course is started. For patients who have already used the fasting course and know how to carry it out, the fasting course contains, as a rule, only the main fasting cycle, including sequential stages that are not separated from each other: initial, main and final. First, for one day to three days, they abstain from food and water, but they use water, and, if desired, urine (initial stage), then for 11 days or more they abstain from any food and liquid (main stage), and then for one day to three days abstain from food and liquids, but use water, and, if desired, urine (final stage). At the main stage of the main fasting cycle, mouth rinsing is performed. Water is most suitable for rinsing the mouth, including cool water. Other edible liquids such as beverages can also be used. However, you should not use dark or brightly colored edible liquids or herbal tinctures, so as not to spoil the color of the tooth enamel. After rinsing the mouth, the water (liquid) must be carefully spit out. The fasting course is carried out against the background of self-coding and guided imagination to achieve healing. Additionally, during the main fasting phase of the main fasting cycle, cold procedures (dousing) can be applied.

In addition, throughout the entire course of fasting, breathing exercises, physical exercises and a number of physiological procedures recommended depending on the disease and the patient's condition can be carried out.

For patients who use a fasting course for the first time, the implementation of the method of rehabilitation of the human body also begins with a vegetarian diet with a dietary diet, in particular, a vegetable or vegetable diet in combination with cereals freshly made from whole grains of cereals. This diet should be followed for 10 days. After physiological clearing (emptying), a fasting course begins, which includes at least one additional fasting cycle, and the main fasting cycle is final.

Each additional fasting cycle is carried out as needed and differs from the main fasting cycle only in the duration of the main fasting stage, which in the additional cycle lasts less than 11 days.

So, patients who are using a fasting course for the first time use cascade fasting: from one to 10 additional cycles, each of which includes from one day of abstinence from food and liquids except water and, if desired and in the absence of contraindications, urine (initial stage), further, from one day to 8-11 days (minimum period) abstinence from any food and water (main stage), but at the same time rinsing of the oral cavity is used, and, then, from day to 1 day abstain from food and liquid except for water and, if desired and in the absence of contraindications, urine (final stage). Further, the patient adheres to a vegetarian diet with a diet for one to 10 days. The duration of the meal while following a vegetarian diet may correspond to the duration of the main phase of the previous additional fasting cycle. Then the next cascade begins: an additional fasting cycle, including abstinence from food and liquids except for water and urine for one day to 3 days (initial stage), then for one day to 10 days abstinence from any food and water ( main stage), but at the same time rinses of the oral cavity are used, and, then, for one day or more, they abstain from food and liquids except water and, if desired, urine (final stage), or carry out the main cycle, as described above.

For example, the first time a fasting course can be carried out by applying up to 10 additional cycles with a gradual increase in the main fasting stage of an additional fasting cycle from one to 10 days and, accordingly, from one to 10 days of nutrition, while observing a vegetarian diet with dietary nutrition between additional cycles, as well as between the complementary and main fasting cycle.

At the main fasting stage of each additional cycle and at the main fasting stage of the main cycle, it is allowed to use water for cold procedures (dousing) and for rinsing the mouth. After rinsing the mouth, the water must be carefully spit out. The fasting course is carried out against the background of self-coding and guided imagination to achieve healing.

Thus, the fasting course contains only one fasting cycle, characterized by complete abstinence from food and liquids for a period of 11 days or more (up to 22 days), which is the main and mandatory fasting cycle. But unlike the method according to the prototype, the method of using which it is practically impossible for patients to transfer, except in the supine state, in the claimed method is used before the main complete abstinence from food and liquid for a period of 11 days, the initial stage of fasting for a period of 1 day with the exclusion of food and liquid except water and urine. And at the main stage for a period of 11 or more, mouth rinses are used during the main fasting stage. In addition, they leave the main stage also gradually within 1 day with the exclusion of food and liquid except water and urine. This set of actions reduces the feeling of thirst in patients in comparison with the prototype technique. The result is an alleviation of their condition, due to which there is a decrease in pain in patients.

After a course of fasting, a vegetarian diet with a dietetic diet is used, which is carried out for 5 to 10 days, and for patients with signs of dystrophy - up to 14 days, and against the background of a vegetarian diet with a dietary diet, the patient may receive white clay and / or urine.

During the course of fasting, such unpleasant sensations as: hunger, dizziness, pain, convulsions, weakness, irritability, bad mood, nausea, vomiting, are also present, however, to a lesser extent and less often. In addition, these unpleasant sensations can be dealt with by self-coding, rinsing the mouth, performing breathing exercises, exercise, self-massage, massage and other physiological procedures, including Chinese medicine. In addition, clean air and cold douches help well. At any time of the year, you should walk in the fresh air and, if possible, with open areas of the body. It is also possible to improve the condition with the help of prolonged moderate jogging, breathing with a delay, using the Japanese "Reiki" method (receiving energy for healing), meditation, mental control of the imagination, self-coding.

In severe and advanced forms of the disease, the proposed method can be carried out periodically and regularly until self-healing, between which it is worth using homeopathy. After complete recovery, for the purpose of prevention, the method of rehabilitation of the body should be carried out once every 6 months.

The proposed method is not used for mental illness, hemophilia, cerebral palsy, renal failure and acute infectious kidney disease. The method is not applicable for pregnant women, except for those who know how to use natural energy. This method has not been used for liver cancer, which, however, does not indicate the impossibility or ineffectiveness of such use.

The proposed method was tested on a group of 7 patients who gave written consent to carry out the method of rehabilitation of their body. The implementation of the methodology according to the claimed method of rehabilitation of the human body was carried out on the basis of a sanatorium-resort health-improving complex located on the sea coast.

The examples below demonstrate the realization of the organism of the patient of the above group.

Example 1.

Patient N., 41 years old, diagnosis: cancer of the right breast IIA stage. pT2N0M0. The tumor is located in the central quadrant. She was treated for a year at the place of residence, where she was offered surgical intervention.

I have not used fasting before.

According to the results of primary analyzes in a biological laboratory, the level of typical E. coli bacilli 10 ⁸ CFU / g Feces, lactose-negative E. coli <4 × 10 ⁴ CFU / g Feces, hemolytic E. coli - 0.

Rods of the patient's typical and lactose-negative E.coli strains were taken for cultivation. During the cultivation of E. coli, the patient was kept in vials with saline and stored in a refrigerator.

The patient's first course of fasting and diet included:

- adherence to a vegetable diet in combination with cereals, freshly made from whole grains of cereals - 7 days;

- fasting course (after emptying):

- the main fasting cycle:

- initial stage - 1 day;

- the main stage - 11 days;

- the final stage - 1 day;

- vegetarian diet - 10 days;

I-st additional fasting cycle:

- initial stage - 1 day;

- the main stage - 3 days;

- the final stage - 1 day;

- vegetarian diet - 3 days;

2nd additional fasting cycle:

- initial stage - 1 day;

- the main stage - 6 days;

- the final stage - 1 day;

- vegetarian diet - 6 days;

3rd additional fasting cycle:

- initial stage - 1 day;

- the main stage - 9 days;

- the final stage - 1 day;

- vegetarian diet - 9 days.

At the main stage of fasting of each additional cycle and at the main stage of fasting of the main cycle, water was used to rinse the oral cavity, which patient N. carefully spat out each time, and also water was used for dousing. Rinsing of the mouth was carried out from 20 to 40 times a day, douches - 5-6 times a day.

At the initial and final stages of the main and additional cycles of fasting, patient N. drank water about 1.5 liters per day.

Throughout the fasting course, self-coding and guided imaginations were regularly conducted to achieve healing.

Throughout the course of rehabilitation, gymnastics was performed every morning, including breathing, using the yoga method, air and water procedures were taken daily, moderate massage was carried out, evening walks along the sea coast.

Patient N. tolerated the first course of body rehabilitation well, her general condition improved significantly. The feeling of thirst was moderate, the pain was tolerable.

Three months later, patient N. underwent the second course of rehabilitation according to the following scheme: adherence to a vegetarian diet - 7 days; taking typical E.coli, E.coli lactose-negative sticks after each meal. The level of typical and lactose-negative bacilli E. coli was normal, hemolytic was absent.

Fasting course (after emptying)

The main fasting cycle:

- initial stage -1 day;

- the main stage - 11 days;

- the final stage - 1 day;

- vegetable diet - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal

I-st additional fasting cycle:

- initial stage -1 day;

- the main stage - 5 days;

- the final stage - 1 day;

- vegetarian diet - 5 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

11th additional fasting cycle:

- initial stage - 1 day;

- the main stage - 8 days;

- the final stage - 1 day;

- vegetarian diet - 8 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

At the main stage of fasting of each additional cycle and at the main stage of fasting of the main cycle, water was used to rinse the oral cavity, which patient N. carefully spat out each time, and also water was used for dousing. Rinsing of the oral cavity was carried out 20 to 40 times a day, dousing 5-8 times a day.

At the initial and final stages of the main and additional cycles of fasting, patient N. drank water about 1.5 liters per day.

Throughout the fasting course, self-coding and guided imaginations were regularly conducted to achieve healing.

Throughout the course of rehabilitation, gymnastics was performed every morning, including breathing, using the yoga method, air and water procedures were taken daily, moderate massage was carried out, evening walks along the sea coast.

Patient N. endured the second course of body rehabilitation well, her general condition improved significantly. The feeling of thirst was moderate, the pain was tolerable.

After 4 months, patient N. underwent the third course of rehabilitation according to the scheme:

- fasting course (after emptying):

- the main fasting cycle:

- initial stage - 1 day;

- the main stage - 11 days;

- the final stage - 1 day;

- vegetable diet - 14 days, adherence to a vegetarian diet in combination with porridge from signs - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

At the main stage of fasting of the main cycle, water was used to rinse the oral cavity, which patient N. carefully spat out each time, and also water was used for dousing. Rinsing the mouth was carried out 30-35 times a day, douches - 1 time a day.

At the initial and final stages of the main fasting cycle, patient N. drank water about 1.5 liters per day.

Throughout the fasting course, self-coding and guided imaginations were regularly conducted to achieve healing.

Throughout the course of rehabilitation, gymnastics was performed every morning, including breathing, using the yoga method, air and water procedures were taken daily, moderate massage was carried out, evening walks along the sea coast.

Patient N. endured the third course of body rehabilitation well, the general condition of the body improved. According to the results of diagnostics, the condition improved.

It is recommended: to carry out a course of rehabilitation of the body according to the used method of rehabilitation of the human body 2 times a year.

According to the results of the fasting course, a decrease in pain was observed, and flatulence during a meal was not observed. The patient tolerated the fasting course well.

Example 2.

Patient O., diagnosis: cervical carcinoma, stage III.

She was treated for a year at the place of residence, where she was offered surgical intervention.

I have not used fasting before.

According to the results of primary analyzes in a biological laboratory, the level of typical E. coli bacilli 6 × 10 ⁷ CFU / g Feces, E. coli lactose-negative <6 × 10 ⁴ CFU / g Feces, E. coli hemolytic - 0.

Rods of the patient's typical and lactose-negative E.coli strains were taken for cultivation. During the cultivation of E. coli, the patient was kept in vials with saline and stored in a refrigerator.

The main course of the patient's fasting and diet included:

- adherence to a vegetable diet in combination with cereals, freshly made from whole grains of cereals - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal;

- fasting course (after emptying):

- the main fasting cycle:

- initial stage - 1 day;

- the main stage - 11 days;

- the final stage - 1 day;

- vegetarian diet - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

The level of typical and lactose-negative bacilli E. coli was normal, hemolytic was absent.

In the process of starvation, she could perform some types of work.

According to the results of the course, there was a stable decrease in pain caused by cancer. No pain relievers were required. Flatulence during the meal was not observed. The patient tolerated the fasting course well.

Example 3.

Patient P., 29 years old, diagnosis: overweight dyspepsia syndrome.

Before the course, she used traditional methods of fasting without results, used antacids, antimicrobial drugs, prokinetics. No results.

According to the results of primary analyzes in a biological laboratory, the level of typical E. coli bacilli is 2 × 10 ¹¹ CFU / g Feces, lactose-negative E. coli <3 × 10 ³ CFU / g Feces, hemolytic E. coli - 10 ³ .

Rods of the patient's typical and lactose-negative E.coli strains were taken for cultivation. During the cultivation of E. coli, the patient was kept in vials with saline and stored in a refrigerator.

The main prescribed course of fasting and the patient's diet included:

- adherence to a vegetable diet in combination with cereals, freshly made from whole grains of cereals - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal;

- fasting course (after emptying):

- the main fasting cycle:

- initial stage - 1 day;

- the main stage - 11 days;

- the final stage - 1 day;

- vegetarian diet - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

The level of typical and lactose-negative bacilli E. coli slightly deviated from the norm, the levels were regulated by interrupting the course of E. coli intake. Hemolytic at the level of 500 CFU / g Feces. Oral rehydration was prescribed, in which the patient must drink at least 3 liters of fluid per day. At the end of rehydration, hemolytic E. coli - 0.

In the process of starvation, she could perform some types of work.

According to the results of the course and at its main stage, there was a cessation of painful sensations caused by a violation of the normal activity of the stomach, difficult and painful digestion stopped. Flatulence during the meal was not observed. The patient tolerated the fasting course well.

Example 4.

Patient G., 56 years old, diagnosis: chronic alcoholism of the II degree, characteristic pain in the right hypochondrium.

Before treatment, she underwent a course of rehabilitation, including: relief of disorders caused by intoxication, elimination of the consequences of poisoning the body with ethyl alcohol, treatment of craving for alcohol, treatment of psychological disorders caused by alcohol abuse, rehabilitation. According to the results, after 3 months, a relapse occurred, pain and craving for alcohol resumed.

According to the results of primary analyzes in a biological laboratory, the level of typical E.coli bacilli 10 ⁷ CFU / g Feces, lactose-negative E. coli <2 × 10 ⁴ CFU / g Feces, hemolytic E. coli - 0.

Rods of the patient's typical and lactose-negative E.coli strains were taken for cultivation. During the cultivation of E. coli, the patient was kept in vials with saline and stored in a refrigerator.

The prescribed main course of fasting and the patient's diet included:

- adherence to a vegetable diet in combination with cereals, freshly made from whole grains of cereals - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal;

- fasting course (after emptying):

- the main fasting cycle:

- initial stage - 1 day;

- the main stage - 11 days;

-the final stage - 1 day;

- vegetarian diet - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

The level of typical and lactose-negative bacilli E. coli was normal, hemolytic was absent.

In the process of starvation, she could perform some types of work.

According to the results of the course, there was a cessation of pain in the right hypochondrium, lack of craving for alcohol. At the end of the course, the liver ultrasound data showed an improvement in the condition of this organ. Flatulence during the meal was not observed. The patient tolerated the fasting course well.

Example 5.

Patient D., 49 years old, diagnosis: kidney stone disease.

The treatment used symptomatic conservative medication during renal colic: a heating pad on the kidney area, warm baths and parenteral drug administration: 1 ml of 2% promedol, 1% morphine, 1-2% pantopon in combination with antispasmodics - 1 ml 0.1 % atropine and 1 mg 0.1% platifillin. Periodically applied lumbar blockade according to Vishnevsky.

Recurrences of renal colic are regular.

According to the results of primary analyzes in a biological laboratory, the level of typical E. coli bacilli is 8 × 10 ⁷ CFU / g Feces, lactose-negative E. coli <7 × 10 ⁴ CFU / g Feces, hemolytic E. coli - 0.

Rods of the patient's typical and lactose-negative E.coli strains were taken for cultivation. During the cultivation of E. coli, the patient was kept in vials with saline and stored in a refrigerator.

The main prescribed course of fasting and the patient's diet included:

- adherence to a vegetable diet in combination with cereals, freshly made from whole grains of cereals - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal;

- fasting course (after emptying):

- the main fasting cycle:

- initial stage - 1 day;

- the main stage - 11 days;

- the final stage - 1 day;

- vegetarian diet - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

The level of typical and lactose-negative bacilli E. coli was normal, hemolytic was absent.

In the process of starvation, he could perform some types of work.

According to the results of the course and at its main stage, there was a cessation of pain caused by renal colic, after the exit of all stones from the kidneys, relapses were not observed for six months. Flatulence during the meal was not observed. The patient tolerated the fasting course well.

Without waiting for repeated relapses, the patient underwent an additional course of fasting according to the method, after which there were no relapses of renal colic for six months.

Additional courses of fasting are recommended once every six months.

Example 6.

Patient K., 27 years old, diagnosis: secondary dystrophy against the background of gastritis.

Along with low body weight, he had lethargy and apathy, dryness, peeling of the skin.

Nausea and vomiting were accompanied by sharp pains in the stomach. Against the background of the disease, pyelonephritis developed. Had a symptom of dehydration in the form of thirst.

Before the course, treatment was carried out in a hospital, where it consisted in correcting nutrition (diet), taking enzyme preparations and multivitamins, taking antibacterial and antiviral drugs.

At the end of hospital treatment, a relapse occurred.

According to the results of primary analyzes in a biological laboratory, the level of typical E. coli bacilli is 3 × 10 ¹⁰ CFU / g Feces, lactose-negative E. coli <4 × 10 ¹¹ CFU / g Feces, hemolytic E. coli - 0.

Rods of the patient's typical and lactose-negative E.coli strains were taken for cultivation. During the cultivation of E. coli, the patient was kept in vials with saline and stored in a refrigerator.

The main course of fasting and diet prescribed for the patient included:

- adherence to a vegetable diet in combination with cereals, freshly made from whole grains of cereals - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal;

- fasting course (after emptying):

- the main fasting cycle:

- initial stage - 1 day;

- the main stage - 11 days;

- the final stage - 1 day;

- vegetarian diet - 14 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

The level of typical and lactose-negative bacilli E. coli slightly deviated from the norm, the levels were regulated by interrupting the course of E. coli intake. Hemolytic were absent.

At the stage of the main course of fasting, the feeling of thirst decreased, and after it stopped. In the process of starvation, he could perform some types of work.

At the end of the course of fasting and diet, after a week of the usual lifestyle with active nutrition, there was a cessation of pain caused by sharp pains in the stomach and renal colic.

Lethargy, apathy, peeling of the skin stopped.

Nausea and vomiting were no longer observed within six months.

Flatulence during the meal was not observed. The patient tolerated the fasting course well.

Without waiting for repeated relapses, the patient underwent an additional course of fasting according to the method, after which there were no relapses of renal colic for six months.

Additional courses of fasting are recommended once every six months.

Example 7.

Patient Y., 57 years old, diagnosis: stomach ulcer. Pain symptoms: cramps in the stomach after eating, heartburn up to vomiting, painful digestion in the duodenum with cuts.

Before the course, I used medical treatment: antisecretory (h2-histamine blockers, Na-K-ATPase blockers); gastroprotective agents; antacids; gastrointestinal hormones.

At the end of treatment, after 2 weeks, there was a relapse of the disease in an acute form.

I used Almagel A conservatively, which caused severe constipation.

According to the results of primary analyzes in the biological laboratory, the level of typical E. coli bacilli 6 × 10 ⁸ CFU / g Feces, E. coli lactose-negative <5 × 10 ⁵ CFU / g Feces, E. coli hemolytic - 0.

Rods of the patient's typical and lactose-negative E.coli strains were taken for cultivation. During the cultivation of E. coli, the patient was kept in vials with saline and stored in a refrigerator.

The main prescribed course of fasting and the patient's diet included:

- adherence to a vegetable diet in combination with cereals, freshly made from whole grains of cereals - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal;

- fasting course (after emptying):

- the main fasting cycle:

- initial stage - 1 day;

- the main stage - 11 days;

- the final stage - 1 day;

- vegetarian diet - 10 days; taking typical E.coli, E.coli lactose-negative sticks after each meal.

The level of typical and lactose-negative bacilli E. coli slightly deviated from the norm, the levels were regulated by interrupting the course of E. coli intake. Hemolytic were absent.

According to the results of the course and at its main stage, there was a cessation of pain caused by a stomach ulcer and heartburn, painful digestion in the duodenum stopped.

Relapses were not observed for six months. In the process of starvation, she could perform some types of work.

Flatulence during the meal was not observed. The patient tolerated the fasting course well.

Without waiting for repeated relapses, the patient underwent an additional course of fasting according to the method, after which there were no relapses for six months.

Regular additional courses of fasting are recommended once every six months.

Some of the above patients additionally underwent 3-8 rehabilitation courses according to the proposed method with a further recommendation to use this technique 2 times a year as a prophylaxis.

Thus, the claimed method allows a patient to more easily endure a course of fasting with a reduced feeling of thirst and a reduced feeling of pain in patients, and makes it possible to perform certain types of work during fasting.

Claims (9)

1. A method of conducting a fasting course for seriously ill patients, in which food and liquids are excluded, and before starting the fasting course for 5 to 10 days, they adhere to a vegetarian diet with a diet consisting of a vegetable diet or a vegetable diet in combination with cereals freshly prepared from whole grains cereals; fasting begins after emptying, the fasting course includes the main cycle, which has undivided sequential initial, main and final stages, moreover, the initial stage is carried out for 1-3 days with the exclusion of food and liquid, except for water and urine, the main stage is carried out for at least 11 days with a complete the exclusion of food and liquid, and the final stage is carried out for 1-3 days with the exclusion of food and liquid, except for water and urine, and, at the main stage of the main fasting cycle, rinsing of the mouth is carried out, characterized in that live strains of E. coli typical and lactose-negative E.coli and grow their cultures under artificial conditions, ensure their storage during the entire fasting period, then, when conducting a vegetarian diet, after the final stage of fasting, they receive the grown cultures of typical and lactose-negative E.coli bacilli. the patient's strain; after the first bowel movement, the patient is tested and the level of E. coli bacilli is checked for compliance with the norms, where the norm is considered: typical E. coli sticks 10 ⁷ -10 ⁸ CFU / g Feces, E. coli lactose-negative <10 ⁵ CFU / g Feces , E. coli hemolytic - 0; and in case of a deviation from the norm in case of insufficient level of E.coli bacilli, the corresponding typical and / or lactose-negative bacilli of E.coli strain of the patient are re-taken, and in case of an excess of the level of E.coli sticks, the corresponding typical and / or lactose-negative bacilli are excluded in the next meal E. coli; in case of detecting hemolytic bacilli E. coli, oral rehydration is prescribed, in which the patient should drink up to 3 liters of fluid per day. 2. The method according to claim 1, characterized in that at the end of fasting, a vegetarian diet is used as a dietary food for 10 days, with a dietary diet consisting of a vegetable diet or a vegetable diet in combination with cereals freshly made from whole grains of cereals, and for patients with signs of dystrophy, a vegetarian diet with dietary food is carried out for up to 14 days. 3. The method according to claim 1, characterized in that the intake of food products rich in potassium is carried out. 4. The method according to claim 1, characterized in that during meals between fasting courses, Kaogsil is taken for three weeks in an amount of 250 g. 5. The method according to claim 1, characterized in that the main stage of the main fasting cycle is carried out for 22 days. 6. The method of claim. 1, characterized in that the fasting course further includes at least one additional fasting cycle that is separated from the main cycle or from another additional fasting cycle by a vegetarian diet with diet food, and each additional fasting cycle has unseparated consecutive initial , the main and final stages, moreover, the initial stage is carried out 1-3 days with the exclusion of food and liquid, except for water and urine, the main stage is carried out less than 11 days with the complete exclusion of food and liquid, and the final stage is carried out 1-3 days with the exclusion of food and liquids other than water and urine, and at the main stage of each additional fasting cycle, rinsing the mouth is performed. 7. A method according to claim 1, characterized in that rinsing of the oral cavity during fasting is carried out with water or light drinks. 8. The method according to claim 6, characterized in that the duration of the vegetarian diet with dietary food between two additional fasting cycles or between the additional fasting cycle and the main fasting cycle is from one to 10 days, while the duration of the vegetarian diet with dietary food between two additional fasting cycles is equal to the duration of the main fasting stage of the previous additional fasting cycle. 9. The method according to any one of claims. 1-8, characterized in that after a course of fasting against the background of dietary nutrition, white clay is taken.