RU2730706C2 - Reinforcing agents and method of achieving strength enhancement in an electronic vaping device - Google Patents

Abstract

FIELD: vaping.SUBSTANCE: disclosed is an initial evaporated composition for e-vaping device (60), comprising a vapor generation substance containing propylene glycol or glycerin, and an additive, containing at least one of carvacrol, thymol, monomenthyl succinate and N-(2-hydroxyethyl)-2,3-dimethyl-2-isopropylbutanamide. Disclosed also is e-vaping device (60) comprising cartomizer (70) comprising reservoir (14) holding the original evaporated composition, a mouthpiece and heater (19) configured to heat initial evaporated composition. E-vaping device (60) further comprises a power section connected to cartomizer (70) and comprising tightening sensor (16) configured to detect inhalations made on the mouthpiece, and a power supply configured to supply power to heater (19).EFFECT: strength enhancers and method of achieving strength enhancement in an electronic vaping device are disclosed.17 cl, 3 dwg

Description

The present invention relates generally to a vaporizable precursor formulation for e-vaping devices. More specifically, the present invention relates to strength enhancers in vaporizable formulations.

Electronic vaping devices (or e-vaping devices) are used to vaporize the original vaporizable composition, such as a liquid material, to form vapor for the purpose of inhaling this vapor in an adult vaper. E-vaping devices usually contain a heater that vaporizes the original vaporized composition to form steam. An e-vaping device may contain several e-vaping elements, including a power supply, an e-vaping cartridge or container containing a heater, and a reservoir holding the original vaporized composition.

A tobacco-based smoking article is known to generate steam that produces the desired organoleptic sensations in adult smokers, including a low to moderate pungent response in the throat and perceptible warmth or firmness in the chest of an adult smoker.

With regard to e-vaping devices, the astringency of the vapor, which usually refers to the sensation experienced by an adult vaper in the throat, and the strength of the vapor, which usually refers to the sensation experienced by an adult vaper in the chest, may vary depending on the content and concentration of the original vaporized composition. used to generate steam during vaping performed by an adult vaper. Typically, with the same amount of nicotine in the vaporized formulation, the e-vaping device is more astringent than the tobacco-based product, but its strength is less than that of the tobacco-based product. In addition, as the amount of nicotine in the gas phase of the vapor generated by the e-vaping device increases, the astringency of the e-vaping device increases.

According to a first aspect of the present invention, it relates to an e-vaping apparatus adapted to achieve a desired balance of strength and astringency, the strength increasing without increasing astringency.

According to a second aspect of the present invention, it relates to an e-vaping device that is adapted to provide a perceptual organoleptic sensation in an adult vaper that is similar to that experienced when smoking a tobacco based cigarette.

According to a third aspect of the present invention, it relates to an e-vaping device that is adapted to provide organoleptic sensations, including a level of astringency in the throat and perceived firmness or warmth in the chest, that are similar to the sensory sensations experienced when smoking a product on based on tobacco. When the required balance of strength and astringency is achieved, it is possible to increase the strength of the product for e-vaping without increasing its astringency.

According to a fourth aspect of the present invention, an e-vaping device precursor vaporizable composition comprises a mixture of a vapor generating agent and one or more strength enhancers or additives.

The original vaporizable composition may contain water and / or one or more acids.

The original vaporizable composition can be a liquid composition.

The original vaporizable composition may additionally contain nicotine.

These one or more strength enhancers or additives may contain at least one of the following: carvacrol, thymol, monomenthyl succinate, and N- (2-hydroxyethyl) -2,3-dimethyl-2-isopropyl butanamide.

In at least one embodiment, said one or more strength enhancers or additives may comprise at least one of the following: cinnamaldehyde, menthone, eugenol, zingerone or vanillyl acetone, and gingerol.

These one or more strength enhancers or additives may contain at least one of the following: red pepper, allyl isothiocyanate, piperine, isoevgenol, carvacrol, thymol, menthol, monomenthyl succinate and N- (2-hydroxyethyl) -2,3-dimethyl-2- isopropyl butanamide.

In at least one embodiment, the above and other compounds may be found in extracts such as horseradish oil, garlic extract, onion oil, black pepper, cayenne pepper, ginger oil, thyme oil, cinnamon bark oil , turmeric, fenugreek, cardamom, rosemary extract, grapefruit oil and paniculata andrographis extract. These one or more strength enhancers or additives may contain at least one of these extracts.

Said one or more strength enhancers or additives may contain one or more compounds that activate receptors in the respiratory system of an adult vaper, such as transistor receptor potential cation channel, subfamily A, member 1 (TRPA1), or transistor receptor potential cation channel, subfamily V, member 1 (TPRV1), or nicotinic cholinergic receptors in the adult vaper, so that the agonists become part of the vapor and are carried into the respiratory tract of the adult vaper during vaping.

In at least one embodiment, said one or more strength enhancers or additives may contain, inter alia, one or more of the above compounds in a content range of from about 0.0001 percent to about 1 percent, or in a concentration of up to about 2 percent. If necessary, the concentration of said one or more strength enhancers or additives can be greater than about 2 percent in case multiple strength enhancers are used in combination. For example, the total concentration of strength enhancers can be up to about 5 percent.

In at least one embodiment, astringency-reducing compounds, such as acids, may be included in the original vaporizable composition to provide the desired balance of increased strength and reduced astringency in an e-vaping device.

In at least one embodiment, said one or more strength enhancers or additives may be used in a vaporizable formulation that does not contain nicotine, and said one or more strength enhancers or additives provide a level of strength similar to the strength experienced by an adult vaper during vaping a nicotine-containing device for vaping or smoking a tobacco-based product. For example, such strength enhancers or additives can be included in inhalation devices for treating nicotine addiction.

In at least one embodiment, said one or more strength enhancers or additives increase the strength of the e-vaping device without increasing nicotine delivery and without increasing the astringency of the e-vaping device.

The original vaporizable composition may contain nicotine in an amount of from about 0.5 percent to about 2 percent by weight or more, or from about 0.5 percent to about 5 percent or more. In at least one embodiment, the vapor generated by the vapor generating agent comprises a gas phase and a dispersed phase, and the nicotine concentration in the vapor phase is no more than about 1 percent.

According to a fifth aspect of the present invention, the precursor vaporizable composition in the e-vaping device comprises a mixture of vapor generating agent, nicotine in an amount of from about 0.5 percent to about 2 percent by weight or more, or from about 0.5 percent to about 5 percent or more, and one or more strength enhancers or additives. In at least one embodiment, the vapor generated by the vapor generating agent comprises a gas phase and a dispersed phase, and the nicotine concentration in the vapor phase is no more than about 1 percent. The original vaporizable composition may contain water and / or one or more acids. The original vaporizable composition can be a liquid composition. These one or more strength enhancers or additives may comprise one or more optional or preferred strength enhancers or additives according to the fourth aspect of the present invention.

The initial vaporizable composition according to the fourth or fifth aspect of the present invention may contain one or more acids. The original vaporizable composition may contain one or more acids at a concentration of from about 0.1 percent to about 5 percent.

These one or more acids may have a boiling point of at least about 100 degrees Celsius, and they may be capable of evaporation when heated with a heater in an e-vaping device. The initial vaporizable composition may be capable of forming a vapor having a dispersed phase and a gas phase when heated with a heater in an e-vaping device, the dispersed phase containing protonated nicotine and the gas phase containing unprotonated nicotine. In embodiments, the majority of the nicotine in the vapor is protonated nicotine and a minority of the nicotine is unprotonated nicotine.

In at least one embodiment, the starting vaporizable composition is capable of generating vapor having a nicotine gas phase component when the e-vaping device is operating. The acid can be included in an amount sufficient to reduce the nicotine gas phase component by about 70 percent or more. In other embodiments, the addition of one or more acids allows the gas phase nicotine content to be reduced by an amount ranging from about 40 percent to about 70 percent by weight, or from about 40 percent to about 90 percent by weight.

In at least one embodiment, the acid can be selected such that the liquid-to-vapor transfer efficiency is about 50 percent or more. The acid may be present in an amount sufficient to reduce the content of the nicotine gas phase component.

In at least one embodiment, the acid comprises at least one of the following: pyruvic acid, formic acid, oxalic acid, glycolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid, sorbic acid, malic acid, tartaric acid, succinic acid, citric acid, benzoic acid, oleic acid, aconitic acid, butyric acid, cinnamic acid, capric acid, 3,7-dimethyl-6-octanoic acid, 1-glutamic acid, heptanoic acid, caproic acid , 3-caproic acid, trans-2-caproic acid, isobutyric acid, lauric acid, 2-methylbutanoic acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid, 3-phenylpropionic acid , hydrochloric acid, phosphoric acid and sulfuric acid.

In at least one embodiment, the acid comprises pyruvic acid, lactic acid, benzoic acid, and acetic acid.

The vapor generating agent may contain propylene glycol and glycerol or glycerin. The steam generating agent may contain substantially equal concentrations of propylene glycol and glycerol or glycerin.

The original vaporizable composition may contain water at a concentration of about 10 percent to about 20 percent.

According to a sixth aspect of the present invention, an e-vaping device comprises a first section and a second section. The first section contains a reservoir for the initial vaporizable composition containing the initial vaporizable composition, for example, such as a liquid material, a heater, a wick communicating with the reservoir for the initial vaporizable composition and also communicating with the heater, a mouthpiece and a connector located at the distal end of the first section The second section contains a power supply and a connector located at the proximal end of the second section and configured to buttly connect to the connector of the first section.

According to a seventh aspect of the present invention, an e-vaping device comprises a first section and a second section. The first section can be a cartomizer. The first section contains a reservoir for the initial vaporizable composition containing the initial vaporizable composition, a heater and a mouthpiece. The heater is configured to heat the original evaporated composition. The second section can be a feed section. The second section contains a power supply configured to supply power to the heater. The precursor composition may be the precursor composition according to the fourth or fifth aspect of the present invention, in accordance with any of the embodiments described herein.

The first section may contain a wick in communication with the reservoir for the original vaporizable composition, as well as in communication with the heater. The first section may include a connector located at the distal end of the first section.

The second section may comprise a puff sensor configured to detect puffs being applied to the mouthpiece portion. The second section may include a connector located at the proximal end of the second section and configured to be butt-coupled to the connector of the first section.

The foregoing and other features and advantages of the exemplary embodiments will become clearer from the detailed description of the exemplary embodiments given with reference to the accompanying drawings. The accompanying drawings are intended to illustrate exemplary embodiments and should not be construed as limiting the intended scope of the claims. Accompanying graphics should not be construed as drawn to scale unless explicitly indicated.

FIG. 1 is a side view of an electronic e-vaping device according to one exemplary embodiment;

in fig. 2 is a cross-sectional view of an e-vaping device according to an exemplary embodiment; and

in fig. 3 is a sectional view of yet another exemplary embodiment of an e-vaping device.

Some detailed examples of embodiments are disclosed herein. However, the specific structural and functional details disclosed herein are presented solely for the purpose of describing exemplary embodiments. However, the exemplary embodiments may be embodied in many alternative forms and should not be construed as limited only to the embodiments set forth herein.

Accordingly, although the exemplary embodiments may have various modifications and alternative forms, embodiments shown by way of example in the drawings will be described in detail herein. However, it should be understood that the exemplary embodiments are not intended to be limited to the specific forms disclosed, but rather the exemplary embodiments are intended to encompass all modifications, equivalents, and alternatives within the scope of the exemplary embodiments. Like numbers refer to like elements throughout the description of figures.

It should be understood that if an element or layer is designated as "located on", "connected to", "associated with" or "covering" another element or layer, it may be directly located on, connected to, associated with, or may cover another element or a layer, or intermediate elements or layers may be present. Conversely, if an element is designated as “directly located on,” “directly connected to,” or “directly connected to” another element or layer, then there are no intermediate elements or layers. Like numbers refer to like items throughout the description.

It should be understood that although the terms "first", "second", "third", etc. may be used herein to describe various elements, components, regions, layers or sections, these elements, components, regions, layers or sections should not be limited to these terms. These terms are used only to distinguish one element, component, region, layer or section from another element, component, region, layer, or section. Thus, the first element, component, region, layer or section discussed below may be referred to as the second element, component, region, layer or section without departing from the teachings of the exemplary embodiments.

The terms relative spatial location (eg, "below", "below", "lower", "above", "upper", etc.) may be used herein to simplify the description to disclose the relationship of one element or feature to another. element or feature depicted in the figures. It should be understood that the terms relative spatial arrangement are intended to encompass various orientations of the device during use or operation, in addition to the orientation depicted in the figures. For example, if the device is inverted in the figures, then features described as being “below” or “below” other features or features will appear to be located “above” other features or features. Therefore, the term "under" can encompass both above and below location. The device can be oriented in other ways (rotated 90 degrees or located with other orientations), and the definitions of relative spatial position used in this document will be interpreted accordingly.

The terminology used herein is intended only to describe various embodiments and is not intended to limit the exemplary embodiments. In the context of this document, the singular is intended to include the plural, unless the context clearly dictates otherwise. It should also be understood that the terms "includes", "including", "comprises" and "comprising", when used in the present description, indicate the presence of the specified features, integers, steps, operations, elements or components, but do not exclude the presence or addition of one or more other features, integers, steps, operations, elements, components or groups thereof.

Examples of embodiments are described herein with reference to cross-sectional illustrations that are schematic representations of idealized embodiments (or intermediate structures) of examples of embodiments. Thus, changes in the shapes of these illustrations should be expected as a result of changes, for example, in manufacturing techniques or tolerances. Therefore, the exemplary embodiments should not be construed as being limited to the shapes of the regions depicted herein, but should include deviations in shape that are due, for example, to the manufacturing process. Therefore, the areas depicted in the figures are inherently schematic, and their shapes are not intended to represent the actual shape of the device area, nor are they intended to limit the scope of the exemplary embodiments.

Unless otherwise defined, all terms (including technical and scientific terms) used in this document have the same meanings as commonly understood by those of ordinary skill in the art to which the exemplary embodiments refer. It should also be understood that terms, including those defined in commonly used dictionaries, should be interpreted as having a meaning consistent with their meaning in the context of the relevant field of technology, and should not be interpreted in an idealized or overly formal sense unless explicitly defined in this document.

When the terms "approximately" or "substantially" are used herein in combination with a numerical value, the corresponding numerical value is intended to include an error of ± 10 percent of the indicated numerical value. In addition, when referring to percentages throughout this specification, it is understood that these percentages are based on weight, i. E. represent weight percentages. The expression "not more than" includes numeric values from zero to the expressed upper limit and all values in between. When specifying a range, this range includes all values within its limits, such as increments of 0.1 percent.

In the context of this document, the term "vapor generating agent" describes any suitable known compound or mixture of compounds that, when used, promotes the generation of vapor and is substantially resistant to thermal degradation at the operating temperature of the e-vaping device. Suitable vaporizers consist of various compounds such as polyhydric alcohols, including propylene glycol and / or glycerol or glycerin. In at least one embodiment, the vaporizer is propylene glycol.

FIG. 1 shows a side view of an e-vaping device 60 according to one exemplary embodiment. As shown in FIG. 1, an e-vaping device 60 comprises a first section or cartomizer 70 and a second section 72 that are connected to each other by a threaded connector 74 or other connecting structure, such as one or more of the following: a snap fit, a snap fit, a retainer , clip, latch, etc. In one embodiment, the first section or cartomizer 70 may be a replaceable cartridge and the second section 72 may be a reusable section. Alternatively, the first section or cartomizer 70 and the second section 72 may be integrally formed in one piece.

FIG. 2 is a cross-sectional view of an exemplary embodiment of an electronic e-vaping device. As shown in FIG. 2, the first section or cartomizer 70 may include an insert 20 at the mouth end, a capillary steam generator comprising a capillary tube 18, a heater 19 for heating at least a portion of the capillary tube 18, and a reservoir 14.

The second section 72 may comprise a power supply 12, a control circuit 11 configured to control the power supply 12, and a puff sensor 16. The puff sensor is configured to detect the fact of a puff by an adult vaper on the electronic device 60 for e-vaping, as a result of which the operation of the power supply 12 is initiated by the control circuit 11 to activate the heater 19 in order to heat the vapor composition contained in the reservoir 14, and steam formation. The threaded portion 74 of the second section 72 may be connected to a battery charger, if not connected to the first section or cartomizer 70, to charge the battery or power source 12.

As shown in FIG. 3, in other exemplary embodiments, the valve 40 may be a two-way valve and the reservoir 14 may be pressurized. For example, the reservoir 14 may be pressurized by a pressure application mechanism 405 configured to apply constant pressure to the reservoir 14. This facilitates the emission of steam generated by heating the initial vaporizable composition contained in the reservoir 14.

In the exemplary embodiments, the capillary tube 18 is formed from or contains a conductive material and thus acts as its own heater 19 when current flows through the tube. Capillary tube 18 can be any electrically conductive material that is capable of resistive heating while maintaining the desired structural integrity at operating temperatures exposed to capillary tube 18 and that does not react with the volatilized composition. Suitable materials for forming capillary tube 18 are one or more of the following: stainless steel, copper, copper alloys, porous ceramic materials coated with film resistive material, nickel-chromium alloys, and combinations thereof. For example, capillary tube 18 is a stainless steel capillary tube 18 and acts as a heater 19 using electrical leads 26 attached thereto to pass DC or AC current along the length of the capillary tube 18. Thus, the stainless steel capillary tube 18 is heated. due to resistive heating. Alternatively, capillary tube 18 can be non-metallic, such as a glass tube. In such an embodiment, the heater 19 consists of or comprises a conductive material capable of resistance heating, such as, for example, stainless steel, nichrome or platinum wire, disposed along a glass tube. When heating a heater located along the glass tube, the initial vaporizable composition in capillary tube 18 is heated to a temperature sufficient for at least partial vaporization of the initial vaporizable composition in capillary tube 18.

In at least one embodiment, at least two electrical terminals 26 are connected to a metal capillary tube 18. In at least one embodiment, one electrical terminal 26 is connected to an upstream first portion 101 of the capillary tube 18 and a second electrical terminal 26 is connected to the downstream end section 102 of capillary tube 18.

During operation, when the adult vaper puffs on the electronic e-vaping device, the puff sensor 16 detects a pressure gradient caused by the adult vaping puff, and the control circuit 11 activates the heater 19 to heat the original vaporizable composition located in the reservoir 14. Once The capillary tube 18 is heated, the original vaporized composition contained within the heated portion of the capillary tube 18 vaporizes and exits the outlet 63, where the initial vaporizable composition expands, mixes with air and forms vapor in the mixing chamber 240.

The power supply 12 in the exemplary embodiments may comprise a battery disposed in the second section 72 of the e-vaping device 60. The power supply 12 is configured to supply voltage to the heater 19, and this heater 19 vaporizes the initial vaporizable composition contained in the reservoir 14.

In at least one embodiment, the electrical contacts or connection between heater 19 and electrical wires 26 are substantially conductive and heat-resistant, while heater 19 is substantially resistive such that heat generation occurs primarily along heater 19, and not on contacts.

The power supply or battery 12 may be rechargeable and include circuitry for charging the battery with an external charger. In this case, the specified circuit, when charged, supplies power for a certain number of puffs, after which the specified circuit must be reconnected to the external charger.

In at least one embodiment, the e-vaping device 60 may include a control circuit that may be located on a printed circuit board 11. The control circuit 11 may also include a heater activation light 27 that is configured to ignite when the heater 19 is activated. In at least one embodiment, the heater activation indicator light 27 comprises at least one LED and is positioned at the distal end 28 of the e-vaping device 60 so that the heater activation indicator light 27 illuminates the lid, which, during puffing, becomes a burning coal ... In addition, the heater activation indicator light 27 may be configured to be visible to an adult vaper. The indicator light 27 can also be designed so that the adult vaper can activate and / or deactivate the indicator light 27, if necessary, so that the indicator light 27 is not activated during vaping if necessary.

In at least one embodiment, e-vaping device 60 further comprises an insert 20 at the mouth end having at least two off-axis diverging outlets 21. In at least one embodiment, insert 20 at the mouth end comprises at least two diverging outlets 21 (for example, 3 to 8 outlets or more). In at least one embodiment, the outlet openings 21 of the mouthpiece insert 20 are located at the ends of the off-axis channels 23 and are angled outwardly relative to the longitudinal direction of the e-vaping device 60 (i.e., diverging). In the context of this document, the term “off-axis” means “angled to the longitudinal direction of the e-vaping device”. In addition, the mouthpiece insert (or flow guide) 20 may include outlets evenly spaced around the mouthpiece insert 20 at the mouthpiece end so as to substantially evenly distribute steam in the mouth of an adult vaper during use.

In at least one embodiment, the e-vaping device 60 is approximately the same size as a conventional cigarette. In some embodiments, e-vaping device 60 may be from about 80 millimeters to about 110 millimeters in length, for example, from about 80 millimeters to about 100 millimeters in length, and from about 7 millimeters to about 10 millimeters in diameter.

The outer cylindrical body 22 of the e-vaping device 60 may be formed from or contain any suitable material or combination of materials. In at least one embodiment, the outer cylindrical body 22 is formed at least in part from metal and is part of an electrical circuit connecting the control circuit 11, power supply 12, puff sensor 16, and heater 19.

FIG. 3 is a cross-sectional view of an e-vaping device according to one exemplary embodiment. As shown in FIG. 3, the e-vaping device 60 may also comprise a middle section (third section) 73 which may contain a reservoir 14 for the liquid precursor vaporizable composition and a heater 19. The middle section 73 may be configured to connect to a threaded connector 74 'on the upstream end of the first section or cartomizer 70 and with a threaded connector 74 at the downstream end of the second section 72. In this exemplary embodiment, the first section or cartomizer 70 encloses an insert 20 at the mouth end, while the second section 72 houses the power supply 12 and a control circuit 11 that is configured to control the power supply 12.

In at least one embodiment, the first section or cartomizer 70, the second section 72, and the third section 73 comprise a common outer cylindrical body 22 that extends longitudinally along the length of the e-vaping device 60. Additionally, in at least one embodiment, the middle section 73 is disposable and the first section or cartomizer 70 and / or second section 72 are reusable. Sections 70, 72, 73 may be secured with threaded connections or connectors 74 and 74 ', thereby allowing the middle section 73 to be replaced when the contents of the reservoir 14 are used up. In another embodiment, the first section or cartomizer 70 is replaceable so that eliminate the need to clean the capillary tube 18 and / or heater 19. In at least one embodiment, the first section or cartomizer 70, the second section 72 and the middle section 73 may be formed as a single piece without threaded connections to form a disposable electronic device for e- vaping.

In the exemplary embodiment shown in FIG. 3, reservoir 14 is a tubular elongated body formed from or containing an elastomeric material such that it is flexible and / or compressible when squeezed. In at least one embodiment, the elastomeric material can be one of the following: silicone, plastic, rubber, latex, and combinations thereof.

In at least one embodiment, reservoir 14 is in fluid communication with capillary tube 18 such that when compressed, reservoir 14 is capable of delivering a volume of precursor vaporizable composition, such as liquid material, to capillary tube 18. Concurrent with delivery of precursor vaporizable composition to capillary , the power supply 12 is activated by manually applying pressure to the reservoir 14, and the capillary tube 18 is heated to form a heated region where the original vaporizable composition evaporates. When discharged from the heated capillary tube 18, the vaporized material expands, mixes with air and forms steam.

As shown in FIG. 3, reservoir 14 comprises a valve 40 configured to retain the liquid initial vaporizable composition within reservoir 14 and open when reservoir 14 is squeezed and pressure is applied to reservoir 14. In at least one embodiment, valve 40 opens when a critical minimum pressure is reached. to prevent inadvertent release of the original vaporizable composition from reservoir 14 or activation of heater 19. In at least one embodiment, the pressure required to press the pressure switch 44 is high enough to prevent accidental heating. This design makes it possible to exclude the activation of the heater 19 in the absence of the original vaporized composition pumped through the capillary.

Upon release of pressure from reservoir 14, valve 40 closes and heated capillary tube 18 releases any original vaporizable composition remaining downstream of valve 40.

In at least one embodiment, strength enhancers or additives can comprise cinnamaldehyde, menthone, eugenol, zingerone or vanillyl acetone and gingerol. Strength enhancers may also contain red pepper, allyl isothiocyanate, piperine, isoeugenol, carvacrol, thymol, menthol, monomenthyl succinate, and N- (2-hydroxyethyl) -2,3-dimethyl-2-isopropyl butanamide. Strength enhancers include one or more compounds that activate receptors in the respiratory system of an adult vaper, such as the transistor receptor potential cation channel, subfamily A, member 1 (TRPA1), the transistor receptor potential cation channel, subfamily V, member 1 (TPRV1), or nicotinic cholinergic receptor agonists in adult vaper, so that receptors become part of the dispersed phase and are transferred to the respiratory tract of the adult vaper along with the dispersed phase during vaping.

In at least one embodiment, the above and other compounds may be found in extracts such as horseradish oil, garlic extract, onion oil, black pepper, cayenne pepper, ginger oil, thyme oil, cinnamon bark oil , turmeric, fenugreek, cardamom, rosemary extract, grapefruit oil and paniculata andrographis extract.

In at least one embodiment, the original vaporizable composition may contain one or more strength enhancers in the range of from about 0.0001 percent to about 1 percent, in a concentration up to about 2 percent, or in concentrations from more than about 2 percent to less than about 5 percent when the fortress enhancer is a combination of multiple fortress enhancers. These strength enhancers are capable of activating receptors in the respiratory system of an adult vaper.

In at least one embodiment, a precursor vaporizable composition for an e-vaping device, such as, for example, a liquid composition, comprises a mixture of one or more of the following: a vapor generating agent, one or more strength enhancers, nicotine, one or more acids, and water.

The original vaporizable composition contains water if necessary. Water can be present in an amount from about 5 percent by weight based on the weight of the original vaporizable composition to about 40 percent by weight based on the weight of the original vaporizable composition. For example, water can be present in an amount of about 20 percent by weight, based on the weight of the original vaporizable composition.

The following examples describe various combinations and corresponding concentrations of strength enhancers. The amount of nicotine in various formulations can range from about 0.5 percent to about 1.5 percent, or from about 0.5 percent to about 2 percent. The various fortress boosters are described above. The acid described below includes at least one of the following: pyruvic acid, formic acid, oxalic acid, glycolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid, sorbic acid, malic acid , tartaric acid, succinic acid, citric acid, benzoic acid, oleic acid, aconitic acid, butyric acid, cinnamic acid, capric acid, 3,7-dimethyl-6-octanoic acid, 1-glutamic acid, heptanoic acid, caproic acid, 3-caproic acid, trans-2-caproic acid, isobutyric acid, lauric acid, 2-methylbutanoic acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid, 3-phenylpropionic acid, hydrochloric acid, phosphoric acid and sulfuric acid. Examples of volatile formulations are described below.

EXAMPLE 1: The original vaporizable composition solution contains approximately several ppm. or about 0.001 percent to about 0.1 percent strength enhancer or additive, about 60 percent to about 80 percent steam generating agent (e.g., propylene glycol and glycerin in substantially equal concentrations), about 10 percent to about 20 percent water , from about 0.5 percent to about 2 percent nicotine by weight (NBW) and up to about 5 percent acid.

EXAMPLE 2: A precursor vaporization composition solution contains about 1 percent strength enhancer or additive, about 60 percent to about 80 percent vapor generating agent (e.g., propylene glycol and glycerin), about 15 percent to about 20 percent water, about 1 percent up to about 2 percent nicotine by weight (NBW); and up to about 3 percent acid.

EXAMPLE 3: The original vaporizable formulation contains about 1.5 percent strength enhancer or additive, about 60 percent to about 80 percent of a vapor generating agent (e.g., propylene glycol and glycerin), about 15 percent to about 20 percent water, about 0 , 5 percent to about 1.5 percent nicotine by weight (NBW) and up to about 1 percent acid.

EXAMPLE 4: A precursor vaporizable composition solution contains about 2 percent strength enhancer or additive, about 60 percent to about 80 percent steam generating agent (e.g., propylene glycol and glycerin), about 15 percent to about 20 percent water, about 0, 5 percent to about 2 percent nicotine by weight (NBW) and substantially 0 percent acid, or about 0.1 percent acid.

EXAMPLE 5: A precursor vaporizable composition solution contains about 2 percent to about 5 percent of a combination of a variety of strength enhancers or additives, about 60 percent to about 80 percent of a vapor generating agent (e.g., propylene glycol and glycerin), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent nicotine by weight (NBW), and substantially 0 percent acid, or about 0.1 percent acid.

EXAMPLE 6: A precursor vaporizable composition solution contains about 0.1 percent of one of the following: cinnamaldehyde, menthone, eugenol, zingerone or vanillyl acetone, and gingerol, about 60 percent to about 80 percent of a vapor generating agent (e.g., propylene glycol and glycerin), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent nicotine by weight (NBW), and up to about 5 percent acid.

EXAMPLE 7: A precursor vaporizable composition solution contains about 1 percent of one or more of the following: cinnamaldehyde, menthone, eugenol, zingerone or vanillyl acetone, and gingerol, about 60 percent to about 80 percent of a vapor generating agent (e.g., propylene glycol and glycerin), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent nicotine by weight (NBW), and up to about 3 percent acid.

EXAMPLE 8: A precursor vaporizable composition solution contains about 1.5 percent of one or more of the following: cinnamaldehyde, menthone, eugenol, zingerone, or vanillyl acetone, and gingerol, about 60 percent to about 80 percent of a vapor generating agent (e.g., propylene glycol and glycerin ), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent nicotine by weight (NBW), and about 1 percent acid. Alternatively, the original vaporizable composition contains approximately 1.5 percent of a combination of two or more of the following: cinnamaldehyde, menthone, eugenol, zingerone or vanillyl acetone, and gingerol.

EXAMPLE 9: A stock vaporizable composition solution contains about 2 percent of a combination of the following: cinnamaldehyde, menthone, eugenol, zingerone, or vanillyl acetone, and gingerol, about 60 percent to about 80 percent of a vapor generating agent (e.g., popylene glycol and glycerin), from about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent nicotine by weight (NBW), and substantially 0 percent acid.

EXAMPLE 10: A precursor composition solution contains more than about 2 percent of more than one of the following: cinnamaldehyde, menthone, eugenol, zingerone or vanillyl acetone, and gingerol, about 60 percent to about 80 percent of a vapor generating agent (e.g., propylene glycol and glycerin ), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent nicotine by weight (NBW), and essentially 0 percent acid. Alternatively, the original volatile composition contains more than about 2 percent of a combination of two or more of the following: cinnamaldehyde, menthone, eugenol, zingerone or vanillyl acetone, and gingerol.

EXAMPLE 11: A stock solution of a volatile composition contains from about 0.1 percent to about 2.5 percent of a combination of the following: horseradish oil, garlic extract, onion oil, black pepper, cayenne pepper, ginger oil, thyme oil, cinnamon bark oil , turmeric, fenugreek, cardamom, rosemary extract, grapefruit oil, and andrographis paniculata extract, about 60 percent to about 80 percent steam generating agent (e.g., propylene glycol and glycerin), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent nicotine by weight (NBW), and optionally up to about 5 percent acid.

EXAMPLE 12: A precursor vaporizable formulation solution for a nicotine addiction device contains about 0.1 percent to about 2 percent strength enhancer or additive, about 60 percent to about 80 percent of a vapor generating agent (e.g., propylene glycol and glycerin), from about 10 percent to about 20 percent water, about 0.5 percent to about 2 percent nicotine by weight (NBW), and about 0.1 percent to about 5 percent acid.

In at least one embodiment, the acid is activated by generating steam from the original vaporizable composition upon activation of the e-vaping device to reduce the perceived astringency in the throat, while the strength enhancer is activated by the steam to increase the perceived strength of the vapor.

According to at least one exemplary embodiment, the acid is transferable to the vaporized composition. The efficiency of acid transfer from liquid to vapor is the ratio of the mass fraction of acid in the evaporated composition to the mass fraction of acid in the original evaporated composition. In at least one embodiment, the transfer efficiency of acid from the original vaporizable composition, such as liquid, to vapor is about 50 percent or more, such as about 60 percent or more. For example, pyruvic acid, tartaric acid, acetic acid, and glycolic acid have a liquid-to-vapor transfer efficiency of about 50 percent or more. In at least one embodiment, the precursor vaporizable composition comprises an acid having a liquid-to-vapor transfer efficiency of about 50 percent or more. In yet another embodiment, the original vaporizable composition does not contain any acid having a liquid-to-vapor transfer efficiency of about 25 percent or less.

In at least one exemplary embodiment, the acid has a boiling point of at least about 100 degrees Celsius and may be included in the vaporizable composition in an amount sufficient to adjust the pH of the vaporizable composition to a range of from about 3 to about 8.

According to at least one exemplary embodiment, the starting vaporizable composition comprises one or more of the following: pyruvic acid, formic acid, oxalic acid, glycolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid, levulinic acid , sorbic acid, malic acid, tartaric acid, succinic acid, citric acid, benzoic acid, oleic acid, aconitic acid, butyric acid, cinnamic acid, capric acid, 3,7-dimethyl-6-octanoic acid, 1-glutamic acid, heptanoic acid, caproic acid, 3-caproic acid, trans-2-caproic acid, isobutyric acid, lauric acid, 2-methylbutanoic acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid , 3-phenylpropionic acid, hydrochloric acid, phosphoric acid, sulfuric acid that and their combinations. The acid can also be included in the form of a salt. The original vaporizable composition also contains a substance for generating steam, if necessary, water, nicotine and flavorings.

Thus, the examples of embodiments have been described above, and it is obvious that the same examples may vary in different ways. Such variations are not to be construed as a departure from the intended scope of the exemplary embodiments, and all such modifications as will be apparent to those skilled in the art are intended to be included within the scope of the following claims.

Claims (33)

1. The original vaporized composition for electronic device for e-vaping, containing a vapor generating agent containing propylene glycol and / or glycerin; nicotine; one or more acids at a concentration of 0.1 percent to 5 percent; an additive containing at least one of the following: carvacrol, thymol, monomenthyl succinate and N- (2-hydroxyethyl) -2,3-dimethyl-2-isopropyl butanamide. 2. The original vaporizable composition of claim 1, wherein the additive further comprises at least one of the following: piperine, allyl isocyanate, red pepper, isoevgenol, and menthol. 3. The initial volatile composition according to claim 1 or 2, in which the additive is an extract of at least one of the following: zingerone, garlic extract, onion oil, thyme oil, cinnamon bark oil, turmeric, fenugreek, cardamom, extract rosemary, grapefruit oil and andrographis paniculata extract. 4. The original volatile composition according to any of the preceding claims, wherein the additive further comprises an extract of at least one of the following: cinnamaldehyde, menthone, eugenol, horseradish oil, black pepper, cayenne pepper, and ginger oil. 5. The original vaporizable composition according to any of the preceding claims, wherein the concentration of the additive is in the range of 0.0001 percent to 1 percent. 6. The vaporizable composition according to any one of the preceding claims, wherein the concentration of the combination of the plurality of additives in the vaporized initial composition is greater than 2 percent. 7. The vaporizable feed composition of claim 6, wherein the concentration of the combination of the plurality of additives in the vaporized feed composition is from 2 percent to 5 percent. 8. The initial vaporizable composition of claim 1, wherein the concentration of nicotine in the gas phase of the vapor-generating substance is not more than 1 percent. 9. The original vaporizable composition according to claim 1 or 8, wherein the nicotine concentration is in the range of 0.5 percent to 2 percent by weight. 10. The initial vaporizable composition according to any one of the preceding claims, wherein the vapor generating agent contains substantially equal concentrations of propylene glycol and glycerin. 11. The original volatile composition according to any of the preceding claims, additionally containing water in a concentration of 10 percent to 20 percent. 12. The initial vaporizable composition according to claim 1, in which the acid contains at least one of the following: pyruvic acid, formic acid, oxalic acid, glycolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid , sorbic acid, malic acid, tartaric acid, succinic acid, citric acid, benzoic acid, oleic acid, aconitic acid, butyric acid, cinnamic acid, capric acid, 3,7-dimethyl-6-octanoic acid, 1-glutamic acid, heptanoic acid, caproic acid, 3-caproic acid, trans-2-caproic acid, isobutyric acid, lauric acid, 2-methylbutanoic acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid , 3-phenylpropionic acid, hydrochloric acid, phosphoric acid and sulfuric acid. 13. The original vaporizable composition of claim 1 or 12, wherein the acid has a liquid-to-vapor transfer efficiency of greater than 50 percent. 14. An e-vaping device containing a cartomizer containing a reservoir holding the original evaporated composition, a mouthpiece and a heater configured to heat the original evaporated composition; and a power section connected to the cartomizer and containing a puff sensor configured to detect puffs performed at the mouthpiece end, and a power source configured to supply power to the heater; and the original evaporated composition contains: a steam generating agent containing a combination of propylene glycol and glycerin; and nicotine; one or more acids at a concentration of 0.1 percent to 5 percent; an additive containing at least one of the following: carvacrol, thymol, monomenthyl succinate and N- (2-hydroxyethyl) -2,3-dimethyl-2-isopropyl butanamide. 15. An e-vaping device according to claim 14, wherein the additive is an extract of at least one of the following: zingerone, garlic extract, onion oil, thyme oil, cinnamon bark oil, turmeric, fenugreek, cardamom, extract rosemary, grapefruit oil and andrographis paniculata extract. 16. An e-vaping device according to claim 14 or 15, wherein at least one of the following is provided: the concentration of the additive is in the range from 0.0001 percent to 1 percent; and the concentration of the combination of the multiple additives in the starting vaporizable composition is greater than 2 percent. 17. Device for e-vaping according to any one of paragraphs. 14-16, in which at least one of the following is provided: the concentration of nicotine in the vapor phase of the vapor-generating substance is not more than 2 percent; the original evaporated composition additionally contains water in a concentration of 10 percent to 20 percent; and the initial vaporizable composition additionally contains an acid in a concentration of 0.1 percent to 5 percent, in which the efficiency of transfer from liquid to vapor is more than 50 percent.

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