RU2661755C1 - Injection device - Google Patents

Abstract

FIELD: medicine.SUBSTANCE: invention relates to medicine. Injection device with the adjusting member that is configured in order to adjust the amount of injected liquid, which is squeezed out of the injection device, and has the possibility of its rotation relative to the body of the injection device about the central longitudinal axis of the injection device in the first direction of its rotation and with the possibility, when squeezing the injected liquid from the injection device, of its rotation in the second direction of rotation opposite to the first direction of its rotation. Adjusting member is connected to the housing by means of the first threaded connection and has the possibility of its rotation in the distal direction when adjusting the squeezed amount of the injected liquid in addition to the rotation in the first direction of rotation and with the possibility of moving in the proximal direction when extruding the predetermined amount of the injected liquid in addition to the rotation in the second rotation direction, and with the locking device that detects at least one fixing position of the adjusting member. Locking device operates between the adjusting element and the body, the locking device being operative at least when adjusting the amount of the injected liquid, which is squeezed out from the injection device. Each fixing position corresponds to the unique rotation position of the adjusting element with respect to the body.EFFECT: invention provides for several locking positions that are located at different distances.14 cl, 30 dwg

Description

Technical field

The invention relates to an injection apparatus of the type indicated in the restrictive part of paragraph 1.

State of the art

From the patent document EP 1610848 B2, an injection apparatus is known which has a tube with a scale as an adjusting element. When adjusting the squeezed out quantity of injected liquid, the tube with the scale moves in the distal direction. When extruding the squeezed out quantity of injected liquid, the tube with the scale moves in the opposite direction. The tube with the scale is threadedly connected to the body, so that in addition to moving in the distal or proximal direction, the tube with the scale also rotates relative to the body. In addition, the injection apparatus has a locking device that acts between the threaded part and the housing. When adjusting the squeezed out quantity of injected fluid, the threaded part rotates relative to the housing. When extruding the squeezed out quantity of injected liquid, the threaded part is carried out in the housing in the axial direction, so that the fixing device does not work when the dose is extruded, and the clicks of the fixing device are not audible.

The injection apparatus known from patent document EP 1 610 848 B2 has a fixed step size for dispensing. If for therapy it is required, for example, to establish the amount of injected liquid of 0.20 ml and 0.25 ml, the known injection devices are designed in such a way that it is possible to adjust the dosage in increments of not more than 0.05 ml. This means, on the one hand, that the user has to overcome several fixation positions until he reaches the smallest of the doses prescribed for therapy. On the other hand, with the smallest constant step size for dosing equal to, for example, 0.05 ml, the amount of injected liquid ejected during the preliminary preparation process is relatively large. Therefore, significantly lower dosing steps would be desirable for the preliminary preparation process. However, this leads to a significantly larger number of fixation positions that the user must go through when setting the dose.

Disclosure of invention

The basis of the present invention is the task of creating such an injection apparatus of the usual form, which makes it possible to design with several locking positions located at different distances.

This problem is solved by the injection apparatus with the characteristics of paragraph 1.

This invention provides that each position of the fixation uniquely corresponds to a certain position of the adjusting element with respect to the housing. Because of this, the necessary fixation positions can be located at different distances from each other. For example, for the therapy described initially as an example, a contemplated injection apparatus is possible that provides exactly three fixation positions with volumes of 0.01 ml for the preliminary preparation process and 0.20 ml and 0.25 ml for the injected doses. As a result, the maintenance of the injection apparatus is greatly simplified.

In the injection apparatus according to patent document EP 1610848 B2, the radial position of the threaded part relative to the tube with the scale changes with each injection. When setting the dose, the tube with the scale and the threaded part rotate with respect to the body. When squeezing out the injected liquid, the tube with the scale rotates in the opposite direction, while the threaded part is held in the housing without the possibility of relative rotation and is movable in the axial direction. As a result of this, the rotation position of the threaded part in the housing at a given set dose is uncertain and may change with each injection process. This invention provides, in contrast, that each fixation position corresponds to a unique rotation position of the adjusting element with respect to the housing. Due to this, the locking positions can be located at different distances from each other.

For example, it is possible to skip those fixation positions that are not aligned with the prescribed amounts of injected fluid.

The design is simple if at least one fixing position is determined by at least one first locking element connected without the possibility of relative rotation with the housing, and at least one second locking element interacting with the first locking element and connected without the possibility of relative rotation with the adjustment an element. In this case, the locking elements are always connected without the possibility of relative rotation with the housing or with the adjusting element. Due to the fact that during the injection process the adjusting element together with the second locking element rotates in the opposite direction, in a simple way, an unambiguous rotation position of the adjusting element with respect to the housing, corresponding to each fixation position, is achieved. The locking device preferably comprises a locking part that is movable in the axial direction regardless of the adjusting element. In this case, the locking part is connected without the possibility of relative rotation with the housing. At least one first locking member is located on the fixing part. At least one first and at least one second locking element determines at least one locking position in a first axial position of the locking part and the adjusting element. In at least one second axial position of the fixing part and the adjusting element, the locking elements are disengaged, regardless of the rotation position of the adjusting element relative to the fixing part. In this case, the first axial position and the second axial position are the positions of the fixing part and the adjusting element with respect to each other in the axial direction. In this case, the position of the fixing part and the adjusting element relative to the housing may vary. Due to the fact that the locking elements in the second axial position of the fixing part and the adjusting element do not interact, the adjusting element may remain in the second axial position relative to the fixing part. The second axial position preferably occurs when the injected fluid is squeezed out of the injection apparatus. As a result, when squeezing out the injected liquid, clicks of the locking device are not heard. The force required to squeeze out the injected fluid can also be negligible even at those fixation positions that, when adjusting the squeezed out amount of the injected fluid, are clearly audible and palpable.

The injection apparatus preferably comprises a spring which compresses the locking part towards the first axial position. The spring is, in particular, a pressure or tension spring, which exerts a force on the locking part in the direction of the central longitudinal axis of the injection apparatus. If no force counteracts the spring, then the locking device is active. The locking elements are preferably directed along the axis and act in the axial direction. Before reaching the fixation position, at least one locking element is preferably deflected in the direction of the central longitudinal axis of the injection apparatus.

The locking device preferably allows in each locking position the rotation of the adjusting element with respect to the housing in the first direction of rotation and blocks such rotation in the second direction of rotation. As a result, a reverse rotation after an already set dose is not possible. However, it may also be provided with such a design of the locking device that allows the user to overcome the locking position by pressing in the second direction of rotation. In particular, in the injection apparatus there is a spring which acts between the adjustment element and the housing and which compresses the adjustment element in the second direction of rotation. If the adjustment element is not in the locked position, the spring returns the adjustment element to the nearest lower locked position. The spring is, in particular, a torsion spring. In this case, the locking device is preferably made so that with a torque applied by the spring, the locking device blocks the relative rotation of the adjustment element in the second direction of rotation. However, it is possible to provide a locking device capable of shifting from the locking position in the second direction of rotation to the nearest smaller locking position if the user applies more torque. Appropriate calculation of the locking device and the spring allows you to make it possible to return in the case of a mistakenly set too large a dose. The spring allows you to prevent the stop of the adjusting element in an intermediate position between the locking positions in order to prevent squeezing out an unexpected amount of injected fluid. The injection apparatus preferably comprises a first spring that compresses the locking part toward the first axial position, and a second spring that compresses the adjuster in the second direction of rotation. However, it is also possible that either only the first spring or only the second spring is provided.

The injection apparatus preferably comprises a sleeve that connects the adjustment element without the possibility of relative rotation with the control in the first position and allows rotation of the adjustment element relative to the control in the second position. When adjusting the squeezed out quantity of the injected fluid, the clutch is preferably in the first position, and when squeezing out the injected fluid from the injection apparatus, in the second position. As a result of this, such a control is possible in which the control element, when adjusting the squeezed out quantity of injected liquid, rotates together with the adjusting element, and when squeezing out the squeezed out quantity of injected liquid, it moves in the proximal direction. Since the adjusting element, which rotates in relation to the housing when extruding the injected liquid, is also able to rotate relative to the control element, the control element will not be forced to rotate when extruding the injected liquid. In the preferred case, when squeezing out a dose of the injected liquid, the adjustment element is carried out at least on a part of the trajectory of its movement without the possibility of relative rotation relative to the housing.

The movement of the coupling from the first to the second position is preferably done by moving the control in the proximal direction. The locking part is preferably connected to the control in the axial direction so that the movement of the control in the proximal direction causes the movement of the locking part in the proximal direction. As a result, the inactive position of the locking device is ensured when the clutch is in the second position, that is, when injection is possible. The design is simple if the locking part and the control are rigidly connected to each other in the axial direction and are rotatable relative to each other. The spring, which compresses the locking part in the axial direction, as a result of this also affects the control element. The spring preferably acts on the control in the distal direction, so that when injecting, the control should move in the proximal direction, overcoming the force of the spring.

A simple embodiment of the coupling is obtained if the coupling has first teeth at the adjusting element, which interact with the second teeth at the control. Since during operation the relative position of the control element and the adjusting element can change, since the control element rotates with respect to the housing when adjusting the squeezed out quantity of injected liquid, however, during the injection it is carried out without the possibility of rotation relative to the housing, the coupling must make a connection between the control and the regulatory element without the possibility of relative rotation for all theoretically possible positions of the angle of rotation of the control the adjusting element and relative to each other. This is achieved in a simple manner by means of a corresponding precisely executed gearing.

The adjusting element is preferably connected to the housing via a first threaded connection and is arranged to move in the distal direction when adjusting the extruded amount of the injected liquid, in addition to turning in the first direction of rotation, and to move in the proximal direction when extruding the set amount of injected liquid, in addition to turn in the second direction of rotation. In a preferred embodiment, the path that the adjusting element extends in the distal direction corresponds to the path that the metering piston of the injection apparatus must travel to extrude a predetermined amount of injected liquid. This is particularly advantageous when a spring acts between the adjusting element and the housing, which compresses the adjusting element in the second direction of rotation. In this case, the rotation of the adjusting element in the second direction of rotation, which causes extrusion of a predetermined amount of injected liquid, is preferably caused by a spring, so that extrusion of a predetermined amount of injected liquid occurs automatically after being released from the fixation position.

In a preferred case of use, the injected liquid is located in a substantially cylindrical glass container, which is closed on one side by a stopper and on the other side by a sealing disk. The sealing disc is pressed against the reservoir by means of a flare cap. Before the injection fluid can be squeezed out, the sealing disc must be punctured with an injection needle. To squeeze out the injected liquid, the stopper with the metering piston of the injection apparatus moves to the desired distance, as a result of which an appropriate amount of injected liquid is squeezed out through the injection needle. The control element is preferably connected without the possibility of relative rotation with the feed part, and the feed part through the second threaded connection is connected to the metering piston. The metering piston is held without relative rotation relative to the housing. As a result, when adjusting the squeezed out amount of the injected liquid, the feed part moves in the distal direction by means of a second threaded connection. Since when the extruded amount of the injected liquid is extruded, the feed part is connected without the possibility of relative rotation with the control element, when the injected fluid is extruded, the feed part does not rotate, but only moves in the proximal direction. As a result, the metering piston also moves in the proximal direction and moves the capsule of the carpula. The adjusting member preferably acts on the feed member in such a way that moving the adjusting member in the proximal direction causes the feed member to move in the proximal direction. In this case, in particular, it is possible to perform the first and second threaded connections in such a way that, when adjusting the extruded amount of the injected liquid, the adjustment element passes at least the same distance in the distal direction as the delivery part. Preferably, it is provided that the feed part and the adjusting element extend approximately the same distance in the distal direction.

Brief Description of the Drawings

An embodiment of the invention is explained below on the basis of the drawing. Showing:

FIG. 1 side view of the injection apparatus before adjusting the squeezed amount of the injected liquid,

FIG. 2, the injection apparatus of FIG. 1 after setting the squeezed out amount of the injected liquid,

FIG. 3 is a side view of the injection apparatus from figures 1 and 2 after squeezing out the injected liquid, the holder for the capsule being removed,

FIG. 4 is a section along line IV-IV in FIG. 3

FIG. 5 is a section along line IV-IV in FIG. 3 in the position of the injection apparatus according to FIG. one,

FIG. 6 is a section along line IV-IV in FIG. 3 in the position of the injection apparatus according to FIG. 2

FIG. 7 is a side view of the control apparatus of the injection apparatus,

FIG. 8 is a section along line VIII-VIII in FIG. 7,

FIG. 9 is a bottom view of the control in the direction of arrow IX in FIG. 7,

FIG. 10 side view of the feed part of the injection apparatus,

FIG. 11 is a section along line XI-XI in FIG. 10,

FIG. 12 is a side view of a metering piston of an injection apparatus,

FIG. 13 is a section along line XIII-XIII in FIG. 12,

FIG. 14 is a perspective view of a control element of an injection apparatus,

FIG. 15 is a side view of the adjusting member of FIG. fourteen,

FIG. 16 is a section along line XVI-XVI in FIG. fifteen,

FIG. 17 is a section along line XVII-XVII in FIG. fifteen,

FIG. 18 is a section along line XVIII-XVIII in FIG. fifteen,

FIG. 19 is a side view in the direction of arrow XIX in FIG. fifteen,

FIG. 20-23 is a side view of the adjusting member of FIG. fourteen,

FIG. 24 is a perspective view of a fixing part of an injection apparatus,

FIG. 25 is a side view of the fixing part of FIG. 22,

FIG. 26 is a section along line XXVI-XXVI in FIG. 25,

FIG. 27 is a plan view of the fixing part in the direction of arrow XXVII in FIG. 25,

FIG. 28 is a bottom view in the direction of arrow XXVIII in FIG. 25,

FIG. 29 is a side view of the upper part of the housing of the injection apparatus,

FIG. 30 is a section along the line XXX-XXX in FIG. 29.

The implementation of the invention

In figures 1 and 2 shows the injection apparatus 1, which serves to install and squeeze out the prescribed amount of injected liquid from the capsules held in the injection apparatus 1. The injection apparatus 1 has a housing 2, which includes an upper part 3 of the housing, and a holder 4 located in the upper part 3 of the housing. A holder is located in the holder 4, which preferably includes a transparent reservoir 78 with injected liquid and a plug located in the reservoir 78 79, preferably visible from the outside. The holder 4 in the embodiment has two opposite indicator windows 7 through which the user sees how much injected liquid is still contained in the reservoir 78. The metering piston 12 of the injection apparatus 1 is adjacent to the plug 79. The metering piston 12 has a piston rod 13 on which the piston disk 14 is held. The disk 14 of the metering piston 12 is adjacent to the plug 79 of the reservoir 78 and extrudes the injected fluid, moving the plug 79 in the proximal direction. In this case, the proximal direction means the direction of injection, that is, the direction to the nest for the injection needle or the direction in which the injected liquid is squeezed out of the reservoir 78. The distal direction means the opposite direction, that is, the direction of removal from the injection needle. The distal end of the injection apparatus is the end opposite to the injection needle held in the injection apparatus. The “proximal” side is the side of the injection apparatus that faces the injection site during injection, and the “distal” side is the side that faces in the opposite direction to the injection site.

As shown in FIG. 1 and FIG. 2, on the proximal side of the holder 4 there is an external thread 8, on which an injection needle 9 is mounted. Instead of the external thread 8, any other type of fastening device provided for fixing the injection needle 9 in the holder 4 is also possible. FIG. 2 injection needle 9 is removed so that external thread 8 is visible.

At the distal end of the injection apparatus 1 there is a control organ 6. On the control element 6, on its side facing the upper part 3 of the housing, there are several longitudinal ribs 11 extending parallel to the central longitudinal axis 10 of the injection apparatus 1, which is also shown in FIG. 1. In addition, the upper part 3 of the housing has a recess 5, through which a scale 77 is visible, showing the set amount of injected fluid. When shown in FIG. 1 position of the injection apparatus 1 dose not established. To adjust the dose, it is necessary to turn the control element 6 with respect to the housing 2 in the first direction of rotation 43, which in the embodiment corresponds to a clockwise direction. In this case, the control element 6 moves with respect to the housing 2 in the distal direction, that is, in the direction of the arrow 15.

In the position shown in FIG. 2, the dose is set, which in this embodiment is indicated by the number "4". In order to squeeze out the set dose, the control 6 must move relative to the housing 2 in the proximal direction, i.e. in the direction of arrow 45 in FIG. 2. In this case, the user presses the control element 6 in the proximal direction, overcoming the force of the spring 37, described in more detail below (Fig. 4). In FIG. 3 shows the injection apparatus 1 in a position in which the control 6 is moved in the proximal direction to the stop 73 formed between the control 6 and the upper part 3 of the housing. As also shown in FIG. 4, the control element 6 is held in this position without the possibility of rotation with respect to the housing 2 by means of longitudinal ribs 11, which are included in the longitudinal grooves 31 of the upper part 3 of the housing. In order to be able to re-set the squeezable amount of injected fluid, the control 6 must first move in the direction of the central longitudinal axis 10 in the distal direction, as shown by arrow 15, until the longitudinal ribs 11 come out of the longitudinal grooves 31 and the control 6 will be in the position shown in FIG. 1. The movement of the control element 6 in the distal direction is due to those shown in FIG. 4 springs 37. After the control member 6 is moved by the spring 37 in the distal direction, the squeezed out amount of the injected liquid can be reset by turning the control member 6 in the first rotation direction 43.

As shown in figures 3 and 4, the upper part 3 of the housing has a thread 16 at its proximal end, onto which the holder 4 can be screwed on. At the proximal end of the upper part 3 of the housing there is a guide 17 of the piston rod, on the outer side surface of which there is knurled corrugation 18 The guide 17 of the piston rod is connected without the possibility of relative rotation with the piston rod 13. For this, the piston rod 13 has on the longitudinal side at least one cut 19, which interacts in a known manner with sponds to the cut guide 17 of the piston rod. The guide 17 of the piston rod is pressed by a spring not shown to the position shown in figures 3 and 4. If the reservoir 78 is inserted into the holder 4 and the holder 4 is screwed onto the thread 16, then the guide 17 of the piston rod is moved by the tank 78 in the distal direction. As shown in FIG. 4, the piston rod guide 17 has at least one ramp 20, which in the distal position of the piston rod guide 17 interacts with at least one ramp 21 of the upper housing part 3 and as a result connects the piston rod guide 17 without the possibility of relative rotation with the upper part 3 cases. As a result, when the holder 4 is mounted, the piston rod 13 is connected without the possibility of relative rotation with the upper part 3 of the housing. As also shown in FIG. 4, the piston rod guide 17 has a locking edge 22 that interacts with a fixing edge 23 of the upper housing portion 3 and as a result holds the piston rod guide 17, overcoming the force of the spring not shown, in the proximal direction at the upper housing portion 3. The piston rod guide 17 serves to enable the piston rod 13 to be screwed into the upper part 3 of the housing after changing the capsule. In this case, the user has the opportunity to take the guide 17 of the piston rod for knurled corrugation 18 and rotate it relative to the housing 2. With injection devices that do not provide for changing the capsule, the piston rod 13 can be held directly in the upper part 3 of the housing, without the possibility of relative rotation . As shown in FIG. 4, the proximal position of the piston rod guide 17 of the ramp 20 and 21 is disengaged, so that the piston rod guide 17 can rotate relative to the upper part 3 of the housing.

As shown in FIG. 4, the injection apparatus 1 has a feed part 24, which in the embodiment is substantially cylindrical and includes a piston rod 13. The piston rod 13 is connected to the feed part 24 by a threaded connection 27. The rotation of the feed part 24 due to the fixation of the piston rod 13 in the upper parts 3 of the housing without the possibility of relative rotation causes the movement of the feed part 24 in the distal direction. The supply part 24 is connected without the possibility of relative rotation with the control element 6 by means of a longitudinal guide 32. In addition, the injection apparatus 1 has an adjustment element 25. The adjustment element 25 in the embodiment is also made essentially cylindrical and is located on the outer side surface of the delivery part 24. Adjustment the element 25 with its proximal end side 74 abuts against the edge 75 of the feed part 24. The adjusting element 25 is connected by means of a threaded connection 26 with the upper h Stew 3 of the housing. The rotation of the adjusting element 25 in the first direction of rotation 43 (Fig. 1), due to the threaded connection 26, causes the displacement of the adjusting element 25 in the distal direction, and the rotation in the opposite direction of rotation 44 (Fig. 6) causes the displacement of the adjusting element 25 in the proximal direction.

The adjusting element 25 has a jumper 42, which protrudes radially outward from the cylindrical portion of the adjusting element 25 and on which the spring 28 is held. The spring 28 is designed as a torsion spring and its other end is fixed to the upper part 3 of the housing. The spring 28 pushes the adjusting element 25 relative to the upper part 3 of the housing in the direction opposite to the first direction 43 of rotation (Fig. 1).

Between the control element 6 and the adjusting element 25, a clutch 33 acts, which in FIG. 4 is in position 47, in which the clutch 33 is open. In position 47, the clutch 33 allows rotation of the adjusting element 25 relative to the body 6 of the control. The clutch 33 includes teeth 34 on the control 6, which at position 46 of the clutch 33 (Fig. 5) can interact with the teeth 35 on the adjusting element 25 and as a result connect the control 6 and the adjusting element 25 to each other without the possibility of relative turning. As shown in FIG. 4, the teeth 34 have a height b measured parallel to the central longitudinal axis 10. In the position shown in figures 3 and 4, the control member 6 is adjacent to the abutment 73 of the upper part 3 of the housing.

As also shown in FIG. 4, the control element 6 is rigidly axially connected to the fixing part 29. The fixing part 29 is made in the form of a sleeve and is connected to the upper part 3 of the housing by means of a longitudinal guide 36 without the possibility of relative rotation. The locking part 29 is pressed in the distal direction by a spring 37, which in the embodiment is designed as a pressure spring. The fixing part 29 has a recess 80 in which the spring 37 is located. The spring 37 rests on the ledge 81 of the fixing part 29. The recess 80 defines a hollow cylindrical receiver for the spring 37, made between the fixing part 29 and the adjusting element 25. For axially rigid connection of the body 6 of the control with the locking part 29 serves as the locking edge 39 of the control 6, which is included in the recess 38 of the locking part 29. However, it may also be provided that the control 6 acts on the locking the locking part 29 only when moving in the proximal direction, and the movement of the locking part 29 in the distal direction, following the control member 6, occurs due to the spring 37.

The locking part 29 has an end face 50 that faces the edge 40 of the adjusting element 25. The end side 50 is the distal end side of the fixing part 29. On the end side 50, there is a first locking element 30 of the locking part 29. The first locking element 30 in the position shown in FIG. 4 has a distance a to the edge 40, measured in the direction of the central longitudinal axis 10. The locking element 30 is here disengaged from interaction not shown in FIG. 4 by a fixing element in an adjustment part 25 located on the side of the edge 40 that faces the end side 50. The adjustment element 25 and the fixing part 29 in FIG. 4 are in a second axial position 49, in which, regardless of the rotation position of the adjusting element 25 and the fixing part 29, locking between the adjusting element 25 and the fixing part 29 is impossible.

After extruding the injected fluid, the spring 37 moves the control member 6 from the one shown in FIG. 4 in the direction of arrow 15, that is, in the distal direction, until the control 6 reaches the position shown in FIG. 5. The control member 6 has a step 41, which in FIG. 4 is adjacent to the abutment 73, and in FIG. 5 is at a distance c from the abutment 73. The distance c corresponds to that shown in FIG. 4 to the distance a between the locking element 30 and the edge 40. In FIG. 5 shows a locking device 72 formed between the adjusting element 25 and the fixing part 29, in its first axial position 48, in which the first locking element 30 can interact with the locking element located on the adjusting element 25, and determine the fixing position of the injection apparatus 1. The fixing the component 29 in its first axial position 48 abuts with its locking element 30 to the edge 40. As also shown in FIG. 5, the longitudinal ribs 11 in the control 6 are shorter than the distance c, so that in the position of the injection apparatus 1 shown in FIG. 5, the longitudinal ribs 11 come out of the region of the longitudinal grooves 31. When the control 6 is moved in the proximal direction, the teeth 34 of the control 6 are engaged with the teeth 35 of the adjusting element 25. In the embodiment shown in FIG. 5, the first position 46 of the coupling 33 of the control 6 and the adjusting element 25 are connected to each other without the possibility of relative rotation.

To adjust the injection dose, the control 6 must rotate in a first direction 43 of rotation around the central longitudinal axis 10. Due to the connection between the control 6 and the feed part 24 without the possibility of relative rotation, the feed part 24 is also rotated. Due to the second threaded connection 27, the feed part 24 is additionally moved in the distal direction. The adjusting element 25 is also connected to the control body 6 without the possibility of relative rotation by means of the coupling 33 and when it is rotated, it also additionally moves in the distal direction based on the threaded connection 26. In this case, the paths that the supply part 24 and the adjusting element 25 can have are approximately the same length. Preferably, the path that the adjusting member 25 passes is slightly larger than the path of the feed member 24 in order to avoid the metering piston 12 moving in the proximal direction when setting the dose. The locking part 29 is moved in the distal direction by the spring 37 and follows the movement of the adjusting element 25. As a result, the control 6 which is rigidly connected to the fixing part 29 also moves in the distal direction.

In FIG. 6 shows the injection apparatus 1 after adjusting the squeezed out amount of the injected liquid. The step 41 is located from the stop 73 at a distance e, which is significantly greater than the distance c. The feed member 24 has a proximal end face 76 that has shifted in the distal direction compared to the position shown in FIG. 5, at a distance d. The distance e corresponds to the sum of the distance d and the distance c shown in FIG. 5. Through the recess 5 of part 3 of the housing, a jumper 42 of the adjusting element 25 is visible, on the outer side surface of which there is a scale 77 (Fig. 14).

To squeeze out the set amount of injected fluid, the user moves the control element 6 in the proximal direction, overcoming the force of the spring 37, as shown by arrow 45. As a result, the control element 6 moves relative to the adjusting element 25. The sleeve 33 moves to the one shown in FIG. 4, the second position 47. The locking element 30 also moves in the proximal direction relative to the adjustment element 25, so that the first locking element 30 goes out of interaction with the locking element located on the edge 40. By moving the control 6 in the proximal direction, the locking device 72 is moved to the second axial position 49, which is shown in FIG. 4. In the embodiment, the locking device 72 is first disengaged and then the coupling 33 is disconnected. As soon as the coupling 33 and the locking device 72 are disconnected, the adjusting element 25 is rotated by the spring 28 in the second rotation direction 44 (FIG. 6), which is opposite to the first direction of rotation 43. By means of a threaded connection 26, the adjusting element 25 in addition to the rotation is moved in accordance with the arrow 45 in the proximal direction. The end face 74 of the adjusting element 25 acts on the edge 75 of the feed part 24 and moves the feed part 24 in the proximal direction by a distance d. Since the feed part 24 is connected without the possibility of relative rotation with the body 6 of the control, the feed part 24 cannot be rotated. Therefore, the metering piston 12, connected without the possibility of relative rotation with the upper part 3 of the housing, moves in the proximal direction and squeezes the injected liquid from the reservoir.

In figures 7-26 shows in detail the details of the injection apparatus 1. In figures 7-9 shows the control unit 6. In FIG. 7 shows longitudinal ribs 11 on a control member 6. In an embodiment, there are provided four longitudinal ribs 11 located therein, uniformly distributed on the side surface.

As shown in figures 8 and 9, the control 6 is made approximately cylindrical and has a sleeve 55, at the proximal end of which there is a retaining edge 39 protruding inwardly. At its distal end, the sleeve 55 is closed. A sleeve 54 of approximately cylindrical shape is placed inside the sleeve 55, which is completely within the sleeve 55 and has teeth 34 on the proximal side. In the embodiment, the teeth 34 are made on the outside of the pipe 54. The teeth 34 have an outer diameter f. As also shown in figures 8 and 9, jumpers 51 are provided on the inner side surface of the nozzle 54, which cooperate with the groove 52 shown in figures 10 and 11 in the outer side surface of the supply part 24 and connect the control 6 to each other without relative rotation each position of the control element 6 relative to the feed part 24. As shown in figures 6 and 9, the pipe 54 defines a socket 53, which includes the feed part 24.

As shown in FIG. 11, in the region of the edge 75, the supply part 24 has an internal thread 56. The piston rod 13 has the one shown in FIG. 12, an external thread 61, which is screwed into the internal thread 56 of the feed member 24. A shoulder 57 is located at the edge 75, against which the stop 58 of the piston rod 13 abuts, if a dose is set that is greater than the residual amount in the carpule. The stop 58 is located at the distal end of the piston rod 13 and has a larger outer diameter than the external thread 61 of the piston rod 13. In order to be able to mount the piston rod 13 on the supply part 24, the piston disk 14 is made separately from the piston rod 13 and mounted on it. As shown in FIG. 13, on the piston rod 13 there are two cuts 19 located on opposite longitudinal sides of the piston rod 13 for connecting to the guide 17 of the piston rod 13 without the possibility of relative rotation. However, another preferred form of connection is also possible without the possibility of relative rotation.

Figures 14-19 show in detail the design of the adjusting element 25. The adjusting element 25 is also made approximately in the form of a sleeve and has an outwardly facing edge 40, on the proximal side of which a second locking element 60 is located. The second locking element 60 interacts with the locking elements in the locking part 29 and forms with them a locking device 72. In FIG. 15 is a schematic side view of a locking member 60. The locking element 60 is in FIG. 15 beyond the drawing plane. The locking element 60 is made in the form of an inclined platform, and when the adjusting element 25 is rotated in the second rotation direction 44, the front surface of the fixing element 60, which is approximately parallel to the central longitudinal axis 10, is located in front, and the flat inclined surface is located so that it is in front when the adjustment element 25 in the first direction 43 of rotation. An external thread 59 is provided in the proximal region of the feed member 25, which is part of the first threaded joint 26.

As shown in figures 16 and 19, the teeth 35 of the clutch 33 are located on the distal side of the adjusting element 25 and face inward. A portion 63 in the form of a sleeve of an adjusting element 25 is adjacent to the proximal side of the teeth 35, the inner diameter of which g is larger than that shown in FIG. 8 is the outer diameter f of the teeth 34. When the teeth 34 are in the hub-shaped portion 63, the teeth 34 and 35 do not interact with each other, and the control 6 is able to rotate relative to the feed part 25.

As shown in FIG. 17, the second locking element 60 extends over the entire width of the edge 40, measured radially from the central longitudinal axis 10. In the embodiment, a single second locking element 60 is provided. However, another preferred number of second locking elements 60 is also possible, for example, if only a small amount is required the angle of rotation of the control 6 and preferably a distinct perception of the fixation positions by ear and by touch. As shown in FIG. 18, the jumper 42 has an opening 62. A spring 28 is suspended in the opening 62.

In figures 20-23 shows in detail the scale 77 of the adjusting element 25, applied to the jumper 42. The individual values of the scale 77 are at different distances from each other in the direction of the circle. The magnitude of the lateral displacement between the values, that is, their shift in the direction of the central longitudinal axis 10 (Fig. 15), is also different. The distances between the values in the circumferential direction correspond to the distances between the locking elements in the fixing part 29 measured from the center of the scale 77 and are aligned with these values. The different amount of lateral shift is due to the path that the adjusting element 25 passes in the axial direction from one locking position to the next locking position.

Figures 24-28 show in detail the locking part 29. The locking part 29 is made approximately in the form of a sleeve, and on its end face 50 there are first locking elements 30, 64, 65, 66, 67 and 68. The locking element 64 corresponds to the zero position, and the first locking element 65, located at a small distance from the locking element 64 in the circumferential direction, corresponds to the position for preliminary preparation. The locking elements 66, 67, 68 and 30, which are located at different distances from each other, correspond to different set quantities of injected fluid. All the first locking elements 30 and 64-68 are made in the form of inclined surfaces, and when the adjusting element 25 is rotated in the rotation direction 43, the surface in front is slightly beveled, and the surface at the back is abruptly broken. If the adjusting element 25 is moved relative to the fixing part 29 in the first direction of rotation 43, then the surface with a smooth inclination of the second locking element 60 slides along the beveled passing surface of one of the fixing elements 30 and 64-68. As a result of this, a force is exerted on the locking part 29 in the proximal direction, which leads to a deflection of the locking part 29 with overcoming the force of the spring 37. As a result, the achievement of the locking position is audible to the user and feels to the touch.

As shown in figures 24-26, on the locking part 29 immediately next to its end side 50 there is a recess 38, which includes the locking edge 39 of the control 6. As shown in FIG. 26, on the side opposite the end side 50, the fixing part 29 has a recess 80 in which the inner diameter of the fixing part 29 is increased. The recess 80 passes into the area with a smaller inner diameter with a ledge 81. The recess 80 together with the adjusting element 25 limits the receiving space for the spring 37. The spring 37 rests on the ledge 81. As shown in figures 24, 25, 26 and 28, four recesses 69 are evenly distributed on the lateral surface of the fixing part 29. The recesses 69 extend parallel to the central longitudinal axis 10 of the injection apparatus 1 and are used to connect the fixing part 29 to the upper part 3 of the housing without the possibility of a relative turning. FIG. 27 also shows the uneven arrangement of the first locking elements on the end side 50. The first locking elements 30 and 64-68 can be located on the end side 50 in almost any way. In a preferred embodiment, the control 6 rotates to achieve a maximum dose of less than a full revolution. As a result of this, when setting the dose, each fixing element is passed at most once, so that any design of fixing elements and, accordingly, any choice of settable amounts of injected liquid are possible.

In figures 29 and 30 shows the upper part 3 of the housing. As shown in FIG. 29, on the inner side of the upper part of the housing there are three longitudinal ribs 70, which are included in the recesses 69 of the fixing part 29 and as a result hold the fixing part 29 in the housing 2 without the possibility of relative rotation. Part 3 of the housing has in the proximal region an internal thread 71, which interacts with the external thread 59 of the adjusting element 25 (FIG. 14) and forms a first threaded connection 26 with it. As also shown in FIG. 26, the upper housing part 3 at its distal end has a plurality of longitudinal grooves 31, so that it is possible to press the control element 6 into the housing part 3 in different rotation positions.

Due to the fact that when adjusting the squeezed out quantity of the injected liquid, the adjusting element 25 rotates with respect to the housing 2, and when extruding the dose it rotates the same amount back, the adjusting element 25 and the fixing part 29 are held without relative rotation in the housing 2, in each position the fixations are in relation to each other in a uniquely defined rotation position. Since in the case of the adjusting element, which, when setting the dose of the injection, at most one whole revolution passes, the rotation position of the adjusting element also always corresponds to the injection dose, it is possible to provide a separate fixation position for each dose. Intermediate locking positions are not required.

Claims (14)

1. Injection apparatus with an adjusting element (25), which is configured to, when adjusting the amount of injected liquid squeezed out of the injection apparatus (1), rotate with respect to the body (2) of the injection apparatus (1) around a central longitudinal axis (10) the injection apparatus (1) in the first direction (43) of rotation and with the possibility, when extruding the injected liquid from the injection apparatus (1), of rotation in the second direction (44) of rotation opposite to the first direction (43) of rotation, while adjusting the second element (25) is connected to the housing (2) by means of a first threaded connection (26) and is arranged to move in the distal direction when adjusting the extruded amount of the injected liquid in addition to turning in the first direction (43) of rotation and to move in the proximal direction when extruding a predetermined amount of injected fluid in addition to turning in a second rotation direction (44), and with a locking device (72) that determines at least one fixed position the control element (25), wherein the fixing device (72) acts between the adjustment element (25) and the housing (2), and the fixing device (72) acts at least when adjusting the amount of injected liquid squeezed out of the injection apparatus (1), characterized in that each fixation position corresponds to an unambiguous rotation position of the adjusting element (25) with respect to the housing (2). 2. The injection apparatus according to claim 1, characterized in that at least one fixing position is defined by at least one first locking element (30, 64, 65, 66, 67, 68), connected without the possibility of relative rotation with the housing (2 ), and at least one second locking element (60), interacting with the first locking element (30, 64, 65, 66, 67, 68) and connected without the possibility of relative rotation with the adjusting element (25). 3. An injection apparatus according to claim 2, characterized in that the fixing device (72) includes a fixing part (29), which is arranged to move in the axial direction regardless of the adjustment element (25) and is connected without the possibility of relative rotation with the housing (2) and in which at least one first fixing element (30, 64, 65, 66, 67, 68) is located, wherein at least one first fixing element (30, 64, 65, 66, 67, 68) and at least one second locking element (60) in a first axial position of the locking part whether (29) and the adjusting element (25) determine at least one fixing position, and in at least one second axial position (49) of the fixing part (29) and the adjusting element (25) are disengaged regardless of the rotation position of the adjusting element ( 25) relative to the fixing part (29). 4. The injection apparatus according to claim 3, characterized in that the injection apparatus (1) comprises a spring (37), which compresses the fixing part (29) towards the first axial position (48). 5. Injection apparatus according to one of paragraphs. 2-4, characterized in that at least one locking element (30, 64, 65, 66, 67, 68), before reaching the fixation position, deviates in the direction of the central longitudinal axis (10) of the injection apparatus (1). 6. An injection apparatus according to claim 1, characterized in that in each locking position, the locking device (72) allows the adjustment element (25) to rotate relative to the housing (2) in the first rotation direction (43) and blocks the rotation in the second direction (44) rotation. 7. The injection apparatus according to claim 1, characterized in that the injection apparatus (1) comprises a spring (28) that acts between the adjusting element (25) and the housing (2) and which compresses the adjusting element (25) in the second direction (44 ) rotation. 8. The injection apparatus according to claim 1, characterized in that the injection apparatus (1) comprises a sleeve (33), which in the first position (46) connects the adjustment element (25) to the control body (6) without the possibility of relative rotation, and in the second position (47) allows rotation of the adjusting element (25) relative to the control body (6). 9. An injection apparatus according to claim 8, characterized in that the movement of the sleeve (33) from the first position (46) to the second position (47) occurs by moving the control body (6) in the proximal direction. 10. Injection apparatus according to claim 8 or 9, characterized in that the fixing part (29) is connected with the control body (6) in the axial direction so that the movement of the control body (6) in the proximal direction causes the movement of the fixing part (29) in the proximal direction. 11. Injection apparatus according to claim 8 or 9, characterized in that the fixing part (29) and the control member (6) are rigidly connected to each other in the axial direction and are rotatable with respect to each other. 12. An injection apparatus according to claim 8 or 9, characterized in that the clutch (33) has in the adjusting element (25) the first teeth (35) made with the possibility of interaction with the second teeth (34) in the control body (6). 13. An injection apparatus according to claim 8 or 9, characterized in that the control element (6) is connected without the possibility of relative rotation with the feeding part (24), and the feeding part (24) is connected to the metering piston by means of a second threaded connection (27) ( 12), which is held without the possibility of rotation relative to the housing (2). 14. An injection apparatus according to claim 13, characterized in that the adjusting element (25) acts on the feed part (24) in such a way that moving the adjusting element (25) in the proximal direction causes the feed part (24) to move in the proximal direction.

Images