RU2553347C1 - Hair care product - Google Patents

Abstract

FIELD: cosmetology.

SUBSTANCE: hair care product is made in the form of gel, shampoo, lotion. All embodiments comprise aqueous vegetable extracts, phosphonate complex containing potassium-sodium salts of oxyethylidenebisphosphonic acid or their mixture with trisodium salt hexahydrate of phosphonformic acid and a cosmetically acceptable base.

EFFECT: hair care product is recommended for use in medicinal and cosmetic purposes for all ages for prevention and treatment of dystrophic changes in hairy part of the head.

5 cl

Description

The present invention relates to the field of cosmetology and directly relates to means used for hair care.

As you know, the development of various compositions for hair care in the form of gels, shampoos, lotions, creams is one of the urgent tasks of modern cosmetology aimed at solving the problem of strengthening and hair growth.

Hair care products (shampoos, creams, lotions), as you know, usually contain a base and various effective additives. The composition of the basis of any hair product depends on the form (shampoo, cream, lotion) of this product. The composition of the base usually includes in whole or in part such components as a carrier, surfactants, fats, fragrance, preservatives, dye. Alkanols, for example ethanol, polyols, such as polyethylene glycols, glycerin, propanediol, water, are more often used as carriers, and vegetable oils, such as castor, soy, olive, grape, avocado, sea buckthorn, tea tree, etc. are used as fats. (RU 2189806, A61K 7/06, 2002). Such surface-active substances (surfactants) are used such substances as emulsion wax, monoglycerides, lecithin, glycerol oleate, etc. (RU 2131722, A61K 7/06, 1999; RU 2189806, A61K 7/06, 2002).

Cosmetically acceptable preservatives, perfumes and dyes are also usually introduced into the hair formulations.

Most often, well-known hair cosmetics are distinguished from each other by the presence of various additives in them, giving them additional cosmetic and therapeutic properties or enhancing these properties.

A distinctive feature of many well-known hair cosmetics is the presence in them of biologically active compounds of plant and animal origin, which determine the additional cosmetic and therapeutic properties of these products. As you know, biologically active compounds of plant origin are contained in various vegetable oils, for example, soybean, olive, which, as such, are introduced into the hair compositions, or these oils are introduced in the form of plant extracts containing them (RU 2189806, A61K 8/97, 2002) . Water and water-alcohol extracts of various plants are usually used for these purposes. For example, it is known to use water-alcohol extracts of plants such as calamus root and nettle (RU 21202756, А61К 8 / 97.1998), burdock, horse chestnut, nettle, St. John's wort, celandine, mountaineer, thyme, horsetail, mother-and- stepmother, peppermint (RU 2189806, А61К 8/97, 2002). Extracts of fir, chamomile, eucalyptus, wormwood, thyme (RU 2145842, А61К 8/97, 2000) are used as oil extracts.

Of particular interest in the analysis of the studied object is information on the use of the plant extract Rubia tinctorum L. (madder dye). It has long been known to use the extracts of the root of this plant not only as a dye in the textile industry, but also in medicine as a galenic preparation, for example, as part of the Cystenol preparation. A relatively new area is the use of Rubia tinctorum L. (madder dyeing) in the form of an alcohol extract to enhance and restore hair growth, proposed in Japanese patent 1994 (JP H06345623, A61K 8/00, 8/33, 1994). This tool, as stated in the patent description, in addition to extract madder dye may contain purpurins. The solids content of madder dyeing in this tool is 0.01-1 wt. % However, such a known product (in the form of an alcohol extract) has a purely medical purpose and cannot be used for cosmetic purposes, since it causes a strong coloring effect on the hair and scalp, and also causes irritation and dryness of the skin. Cosmetic compositions for hair (in any form) containing Rubia tinctorum L. (madder dyeing) have not yet been identified.

Widely applicable in compositions for hair and biologically active compounds of animal origin, such as protein hydrolysates, preferably keropeptide, casein, collagen, amino acids (RU 2133117, A61K 7/075, 1999; RU 2189806, A61K 8/97, 2002), as well as phospholipids and glycolipids (Kocharovsky BV and other biologically active emulsions in transfusiology. M., 1981).

To stimulate hair growth, chemical compounds are introduced into known agents of a similar purpose. This group of additives includes, for example, organic phosphonates, in particular hydroxyethylidene bisphosphonic acid (and its salts), which, for example, in an amount of 0.1-0.5% by weight, are introduced into a known hair care product made in the form cream-balm and lotion (RU 2189806, АКК 8/97, 2002).

To expand the well-known assortment of hair compositions that have both medicinal and cosmetic properties, there are three options for hair care products made in the form of a gel (option 1), in the form of shampoo (option 2) and in the form of lotion (option 3) . All of these proposed products include aqueous plant extracts, a phosphonate complex containing a potassium sodium salt of hydroxyethylidene bisphosphonic acid or a mixture thereof with trisodium salt of phosphonoformic acid, and a cosmetically acceptable base.

The proposed hair care product, made in the form of a gel, contains aqueous extracts of madder roots, burdock roots, nettle leaves, flax seeds and a phosphonate complex, including the potassium sodium salt of hydroxyethylidene bisphosphonic acid and the trisodium salt of phosphonoformic acid hexahydrate, and contains a cosmetically acceptable base including glycerin, propylene glycol, ethanol, D-panthenol, hydrogenated castor oil, carbomer, triethanolamine, water, preservative and fragrance, at the following weight ratio the content of the mixture components (% wt.): 0.01-1.50 potassium-sodium salt of hydroxyethylidene bisphosphonic acid, 0.001-0.002 - trisodium salt of phosphonic formic acid hexahydrate, 1.0-4.0 - glycerol, 1.0-4.0 - propylene glycol, 0.5-4.0 - ethanol, 0.10-0.15 - D-panthenol, 0.05-0.35 - hydrogenated castor oil, 0.2-0.6 - carbomer, 0.5 -2.0 - triethanolamine, 0.15-0.30 - preservative, 0.05-0.50 - perfume and the rest (up to 100% of the mass.) - water and plant extracts taken in the following weight quantities (% of the mass . in terms of dry residue) in relation to 100% of the mass. final product (gel): 0.30-0.40 - roots of madder dye, 0.30-0.40 - burdock roots, 0.05-0.10 - nettle leaves, 0.05-0.10 - hop haplotype , 0.2-0.5 - flax seeds.

The proposed hair care product, made in the form of a shampoo, contains aqueous extracts of madder roots, burdock roots, nettle leaves, flax seeds and hop fruit, a biologically active compound of animal origin, a phosphonate complex containing potassium-sodium salt of hydroxyethylidene bisphosphonic acid, and a cosmetically acceptable base, including D-panthenol, surfactant, hydrogenated castor oil, carbomer, Trilon B, sodium chloride, citric acid, perfume, preservative and water, at the following weight the ratio of the components of the mixture (% wt.): 0.1-0.5 - phosphonate complex, 11.0-16.0 - biologically active compound of animal origin, 0.10-0.15 - D-panthenol, 13.5 -18.5 - surfactant, 0.05-0.35 - hydrogenated castor oil, 0.1-0.5 - carbomer, 0.1-0.5 - perfume, 0.01-0.05 - Trilon B, 0.1-0.7 - sodium chloride, 0.05-0.1 - citric acid, 0.02-0.08 - preservative, and the rest (up to 100% wt.) - water and aqueous plant extracts taken in the following weight quantities (% of the mass. in terms of dry residue) in relation to 100% of the mass. final product (shampoo): 0.05-0.15 - roots of madder dye, 0.05-0.1 - burdock roots, 0.05-0.1 - nettle leaves, 0.05-0.1 - hop haplotype .

The hair care product, made in the form of a shampoo, contains biologically active compounds of animal origin, selected from the group: collagen, betaine, cocamidopropyl betaine.

The hair care product, made in the form of a shampoo, contains, as a surfactant, substances selected from the group: laureth sulfate, lecithin.

The hair care product in the form of a lotion contains aqueous extracts of madder roots, burdock roots, nettle leaves, rosemary leaves and chamomile flowers, a phosphonate complex containing potassium sodium salt of hydroxyethylidene bisphosphonic acid and phosphonoformic acid trisodium salt hexahydrate, and cosmetically a base containing D-panthenol, hydrogenated castor oil, ethanol, perfume, preservative and water, in the following weight ratio of the components of the mixture (% wt.): phosphonate plex containing 0.01-1.5 - potassium sodium salt of hydroxyethylidene bisphosphonic acid and 0.001-0.002 - trisodium salt of phosphonic formic acid hexahydrate, 0.1-0.15 - D-panthenol, 0.01-0.30 - hydrogenated castor oil, 1.0-5.0 - ethanol, 0.05-0.5 - perfume, 0.05-0.5 - preservative, the rest (up to 100% wt.) - water and aqueous plant extracts taken in the following weight amounts (% wt. in terms of dry residue) in relation to 100% of the mass. final product (lotion): 0.1-0.5 - roots of madder dye, 0.3-0.35 - burdock roots, 0.1-0.15 - nettle leaves, 0.1-0.15 - rosemary leaves , 0.1-0.15 - chamomile flowers.

An essential feature of the proposed composition in all variants of its execution is the presence in the composition of the composition: water extracts of a plant group, where extracts of madder roots, burdock roots and nettle leaves are always present, as well as water extracts of other plants; phosphonate complex, which includes the potassium sodium salt of hydroxyethylene bisphosphonic acid or a mixture thereof with the trisodium salt of phosphonoformic acid; a cosmetically acceptable base containing components specific to each form.

In contrast to the proposed compositions, well-known analogues - cosmetic products for hair, contain other compositions of plant extracts that differ in both qualitative and quantitative composition. In particular, they do not contain madder madder (Rubia tinctorum L.). As additional medical studies have shown, the presence in the proposed tool of madder extract in combination with extracts of other specific plants significantly affects the cosmetic and therapeutic functions of the composition, which was proved by testing the effectiveness of the proposed tools.

As biologically active compounds of plant origin in combination with madder, water extracts of burdock roots and nettle leaves are always introduced into the proposed compositions. Additionally, depending on the chosen form of the proposed product, water extracts of flax seeds and hop haplops are introduced, which also contribute to hair growth and strengthening.

The proposed compositions use freshly prepared water extracts of plants (roots of madder dye, burdock roots, nettle leaves, flax seeds, hop fruit), each of which is prepared separately from pre-ground plant material. The methodology for the preparation and analysis of aqueous extracts complies with established recommendations (Ministry of Health of the Russian Federation, State Pharmacopoeia, XI, issue 2, M., 1990). The solids content in various types of extracts obtained is in the range of 1.6-2.3% of the mass.

A necessary component of the composition is also a phosphonate complex, which is a complex compound - potassium-sodium salt of hydroxyethylidene bisphosphonic acid or its composition with hexahydrate of trisodium salt of phosphonoformic acid, which also stimulates hair growth, but also has a calcium-regulating, membrane-stabilizing and antiseptic effect .

To give the hair strength and elasticity, the composition made in the form of shampoo also contains biologically active compounds of animal origin, namely collagen-fibrillar protein (protein), betaine (trimethylglycine) and its derivative cocamidopropyl betaine, which have a restorative effect on the hair and positively affecting the scalp. These compounds are available, for example, under the trademarks Natural Extract AR, Betaine, Empigen BS / FA, Cocamidopropyl Betaine, Nutrilan 1 Pulver, Hydrolyzed Collagen. As a surfactant, shampoo uses laureth sulfate, lecithin.

As mentioned above, the composition of the basis of the proposed product depends on the form of the product (gel, lotion, shampoo, cream-balm). The composition of the cosmetic base of the proposed funds, made in the form of a gel, are introduced gelling agents (carbomer), emulsifiers (PEG-40 - hydrogenated castor oil, triethanolamine). For example, hydrogenated castor oil of the brand Empigen BS / FA is used, which is a well-known emulsifier.

The basis of the proposed funds in all its forms are introduced alcohols that perform certain functions. For example, glycerol and propylene glycol present in the gel have moisturizing properties, ethanol introduced into the lotion is known to have antiseptic properties, and D-panthenol, introduced into all forms of the proposed product, has regenerative, metabolic and anti-inflammatory properties.

A substance made in the form of shampoo, to remove the negative effects of ions that cause water hardness and prevent foaming, introduces a substance such as Trilon B (disodium salt of ethylenediaminetetraacetic acid). The basis used for the manufacture of shampoo is introduced acrylic polymer-carbomer (carbopol), which is a known gelling agent. As surface-active substances (surfactants), which are also a necessary component of cosmetic hair shampoos, such shampoo uses substances such as lecithin, laureth sulfate. Lecithin, which is a multicomponent mixture of native lipids, in addition to being a powerful emulsifier that allows you to control the stability and dispersion of emulsions, also has high physiological activity and affects the metabolism of skin cells.

Citric acid is also added to the shampoo, which gives the hair a shine that improves the structure of the hair.

The composition of the base, in all forms of its implementation, introduces cosmetically acceptable preservatives, for example methylparaben, 5-chloro-2-methyl-4-isothiazole (Kathon CG), as well as in small quantities of fragrance, for example fragrance "Chamomile super", "Japanese tea".

For the manufacture of cosmetics, the following components are mixed (in compositions 1-6) in a specific weight ratio, expressed in% of the mass.

Below the invention is illustrated by the following examples.

Lotion

Composition 1 (% wt.): Kathon CG (methylchloroisothiazolinone) - 0.15, perfume - 0.17, 20% solution of K-Na salt of hydroxyethylidene bisphosphonic acid (in terms of anhydrous salt) - 0.01, trisodium salt of phosphonoformic acids - 0.002, hydrogenated castor oil - 0.30, Nipagin (methyl paraben) - 0.05 g, ethanol (denatured alcohol, 96%) - 5, D-panthenol - 0.10, perfume ("Super Chamomile" and " Japanese tea "- 0.50), the rest (up to 100% wt.) - purified drinking water and aquatic plant extracts taken in the following weight (% wt. In terms of dry residue) amounts in relation to 100% mass final product (lotion): 0.50 - roots of madder dye, 0.35 - burdock roots, 0.15 - nettle leaves, 0.15 - chamomile flowers, 0.10 - rosemary leaves.

Lotion

Composition 2 (% wt.): 20% solution of K-Na salt of hydroxyethylidene bisphosphonic acid (in terms of anhydrous salt) - 1.50, trisodium salt of phosphonoformic acid - 0.001, Nipagin (methyl paraben) - 0.50, ethanol (denatured , 96%) - 1.0, hydrogenated castor oil - 0.01, D-panthenol - 0.15, perfume ("Super Chamomile" and "Japanese Tea") - 0.05, the rest (up to 100% of the mass .) - purified drinking water and water plant extracts taken in the following weight (% wt. in terms of dry residue) amounts in relation to 100% of the mass. final product (lotion): madder roots - 0.10, burdock roots - 0.30, nettle leaves - 0.10, chamomile flowers - 0.10, rosemary leaves - 0.15.

Gel

Composition 3. (% wt.): Glycerol - 1.0, propylene glycol - 1.0, ethanol rectified from food raw materials - 0.50, triethanolamine - 0.50, Carbopol Ultrez 10 (carbomer) - 0.20, Nipagin M (methylparaben) - 0.10, D-panthenol - 0.10, Eumulgin HRE-40 (PEG-40 hydrogenated castor oil) - 0.05, Kathon CG (methylchloroisothiazolinone) - 0.30, perfume - 0.05 g , 20% solution of potassium-sodium salt of hydroxyethylidene bisphosphonic acid (in terms of anhydrous salt) - 0.01, trisodium salt of phosphonic formic acid hexahydrate - 0.001, the rest (up to 100% by weight) - purified drinking water and aqueous plant extracts, taken in the following weight (% wt. in terms of dry residue) quantities in relation to 100% of the mass. final product (gel): madder roots — 0.30, burdock roots — 0.30, nettle leaves — 0.05, flax seeds — 0.20, hop haplotype — 0.05.

Gel

Composition 4 (% wt.): Glycerol - 4.0, propylene glycol - 4.0, ethanol, rectified from food raw materials - 4.0, triethanolamine - 2.0, Carbopol Ultrez 10 (carbomer) - 0.60, Nipagin M (methylparaben) - 0.15, D-panthenol - 0.15, Eumulgin HRE - 40 (PEG-40 hydrogenated castor oil) - 0.35, preservative-Kathon CG (methylchloroisothiazolinone) - 0.15, perfume - 0.50 , 20% solution of potassium-sodium salt of hydroxyethylidene bisphosphonic acid (in terms of anhydrous salt) - 1.50, trisodium salt of phosphonic formic acid - 0.002, the rest (up to 100%) - purified drinking water and aqueous plant extracts taken in the wake uyuschie weight (% wt. in terms of dry residue) quantities in relation to 100% of the mass. final product (gel): madder roots — 0.40, burdock roots — 0.40, nettle leaves — 0.10, flax seeds — 0.50, hop haplotype — 0.10.

Shampoo

Composition 5 (% wt.): Zetesol 270 / N (laureth sulfate) - 18, lecithin - 0.5, Empigen BS / FA (cocamidopropyl betaine) - 15, Natural extract AR (natural betaine) - 0.97, 20% solution of K-Na salt of hydroxyethylidene bisphosphonic acid (in terms of anhydrous salt) - 0.50, sodium chloride - 0.70, Carbopol Ultrez 10 (carbomer) - 0.50, perfume - 0.50, D-panthenol - 0.10 , Eumulgin HRE-40 (PEG-40 hydrogenated castor oil) - 0.35, citric acid - 0.05, Nutrlan 1 Pulver (hydrolyzed collagen) - 0.03, Kathon CG (methylchloroisothiazolinone) - 0.02, Trilon B ( disodium EDTA) - 0.01, perfume - 0.10, the rest (up to 100%) - purified drinking water and water Extractive extracts taken in the following weight (% wt. in terms of dry residue) amounts with respect to 100% of the mass. final product (shampoo): roots of madder dye - 0.15, nettle leaves - 0.05, burdock roots - 0.05, hop haplotype - 0.05.

Shampoo

Composition 6 (% wt.): Zetesol 270 / N (laureth sulfate) - 13.5, Empigen BS / FA (cocamidopropyl betaine) - 10, Natural extract AR (natural betaine) - 1.0, 20% K-Na solution salts of hydroxyethylidene bisphosphonic acid (in terms of anhydrous salt) - 0.10, sodium chloride - 0.10, Carbopol Ultrez 10 (carbomer) - 0.10, D-panthenol - 0.15, Eumulgin HRE-40 (PEG-40 hydrogenated castor oil) - 0.05, citric acid - 0.10, Kathon CG (methylchloroisothiazolinone) - 0.08, Trilon B (disodium EDTA) - 0.05, perfume - 0.50, the rest (up to 100%) - purified drinking water and aquatic plant extracts taken in the following weight (% wt. in ne eschete dry residue) amounts relative to 100% by weight. final product (shampoo): madder roots - 0.05, nettle leaves - 0.10, burdock roots - 0.10, hop haplotype - 0.10.

The effectiveness of the proposed hair products, performed in all forms (gel, shampoo, lotion), is confirmed by studies conducted in the Laboratory of General Pathology, Federal State Budgetary Scientific Research Institute of Pediatrics and Pediatric Surgery of the Russian Ministry of Health. The study of efficacy in relation to strengthening and restoring the hair structure involved 15 adult patients aged 45-70 years (5 men and 10 women), as well as 5 girls 14-16 years old. The use of cosmetic products in different forms was carried out for 2-3 months for 10 days with intervals of 10 days. Microscopic studies of the hair structure showed that after treatment, the patients established complete elimination of the formation of nodules on the hair shaft, there were signs of an improvement in the microscopic picture of the bulbs, a moderate increase in the number of hair by 10-12% was detected compared with the initial data, spontaneous and forced ( combing) hair loss. Based on the results of testing the effectiveness of the new hair product, it is recommended that it be used for all ages for the prevention and treatment of dystrophic changes in the scalp.

Claims (5)

1. A gel-based hair care product containing a phosphonate complex comprising potassium-sodium salt of hydroxyethylidene bisphosphonic acid and trisodium salt of phosphonic formic acid hexahydrate, as well as aqueous extracts of madder roots, burdock roots, nettle leaves, flax seeds and fruit seeds x and containing a cosmetically acceptable base, including glycerin, propylene glycol, ethanol, D-panthenol, hydrogenated castor oil, carbomer, triethanolamine, water, a preservative and perfume, as follows the weight ratio of the components of the mixture (% wt.):
Hydroxyethylidene Bisphosphonic Acid Potassium Salt 0.01-1.50 Phosphonoformic acid trisodium salt hexahydrate 0.001-0.002 Glycerol 1.0-4.0 Propylene glycol 1.0-4.0 Ethanol 0.50-4.0 D-panthenol 0.10-0.15 PEG-40 hydrogenated castor oil 0.05-0.35 Carbomer 0.20-0.60 Triethanolamine 0.5-2.0 Preservative 0.15-0.30 Perfume 0.05-0.50
and the rest (up to 100% mass.) - water and aqueous plant extracts taken in the following weight quantities (% mass. in terms of dry residue) in relation to 100% of the mass. final product (gel):
Madder Roots 0.30-0.40 Burdock roots 0.30-0.40 Nettle leaf 0.05-0.10 Hop Seedlings 0.05-0.10 Flax seed 0.20-0.50 2. A hair care product in the form of a shampoo containing a biologically active compound of animal origin, a phosphonate complex comprising a potassium-sodium salt of hydroxyethylidene bisphosphonic acid, and containing aqueous extracts of madder roots, burdock roots, nettle leaves and hop haplotypes, and also containing a cosmetically acceptable base, including panthenol, surfactants, hydrogenated castor oil, carbopol, Trilon B, sodium chloride, citric acid, water, from darling and preservative, in the following weight ratio of the components of the mixture (% wt.):
Biologically active compound of animal origin 11.0-16.0 Hydroxyethylidene Bisphosphonic Acid Potassium Salt 0.10-0.50 D-panthenol 0.10-0.15 Surfactant 13.5-18.5 Hydrogenated Castor Oil 0.05-0.35 Sodium chloride 0.10-0.70 Carbomer 0.10-0.50 Lemon acid 0.05-0.10 Trilon-B 0.01-0.05 Preservative 0.02-0.08 Perfume 0.10-0.50
and the rest (up to 100% mass.) - water and aqueous plant extracts taken in the following weight quantities (% mass. in terms of dry residue) in relation to 100% of the mass. final product (shampoo):
Madder Roots 0.05-0.15 Burdock roots 0.05-0.10 Nettle leaf 0.05-0.10 Hop Seedlings 0.05-0.10 3. The tool according to claim 2, containing as a biologically active compound of animal origin products selected from the group: collagen, betaine, cocamidopropyl betaine. 4. The tool according to p. 2, containing as a surfactant compounds selected from the group: laureth sulfate, lecithin. 5. A hair care product in the form of a lotion containing a phosphonate complex, including potassium-sodium salt of hydroxyethylidene bisphosphonic acid and trisodium salt of phosphonoformic acid hexahydrate, as well as aqueous extracts of madder roots, burdock roots, nettle leaves, rosemary leaves and color chamomile and containing a cosmetically acceptable base, including ethanol, D-panthenol, hydrogenated castor oil, water, preservative and perfume, in the following weight ratio comrade mixture (wt.%):
Hydroxyethylidene Bisphosphonic Acid Potassium Salt 0.01-1.50 Phosphonoformic acid trisodium salt hexahydrate 0.001-0.002 D-panthenol 0.10-0.15 Ethanol 1.0-5.0 Hydrogenated Castor Oil 0.01-0.30 Preservative 0.05-0.50 Perfume 0.05-0.50
and the rest (up to 100% mass.) - water and aqueous plant extracts taken in the following weight quantities (% mass. in terms of dry residue) in relation to 100% of the mass. final product (lotion):
Madder Roots 0.1-0.50 Burdock roots 0.3-0.35 Nettle leaf 0.1-0.15 Rosemary leaf 0.1-0.15 Chamomile flowers 0.1-0.15