RU2332866C2 - Dietary supplement "perstevit" - Google Patents

Abstract

FIELD: food products.

SUBSTANCE: invention is related to dietary supplements. Dietary supplement contains extract of leaves and flowers of peach (Persika vulgaris mill) and extract of Stevia grass (Stevia rebaudiana Bertoni). At that in finished product components percent proportion is 80:20.

EFFECT: higher biological activity and wide range of prophylactic actions.

Description

The invention relates to therapeutic and prophylactic agents, is a biologically active food supplement, based on natural plant components, and is intended for use in the food and pharmaceutical industries, with herbal medicine, for the prevention and treatment of tumor diseases.

Known from RF patent No. 2074731, class A61K 35/78, 1997 a phytocomplex for the prevention and treatment of cancer patients, containing a decoction of the collection of medicinal plants, which is a decoction of three collections. At the same time, the first collection contains grass of large celandine, catharanthus pink, White mistletoe with a ratio of 2: 1: 1. The second collection contains yarrow grass, marigold flowers, the root of dandelion officinalis at a ratio of 1: 1: 1. The third collection contains the root of the frangipani, the grass of St. John's wort perforated, the flowers of the narrow-leaved fireweed at a ratio of 1: 1: 1. The first collection may additionally contain chamomile flowers for the pharmacy, the second collection - water pepper and wormwood in the ratio 1: 1, the third collection - the root of the peony evading, plantain large, rhizome of calamus marsh in the ratio 1: 1: 1. All three collections contain valuable medicinal plants that strengthen the immune system, but they are used in small quantities - not more than 1 tablespoon of fresh raw materials per day, which does not provide a sufficient increase in the protective properties of the body. The dosage and method of preparing decoctions only from freshly picked plants are indicated, although mainly it is necessary to apply the fees of both the winter and autumn-spring periods and use dried grass. Also, the use of broths for collecting fresh plants, which insist only 10-15 minutes, does not allow to preserve the necessary healing properties of herbs, their beneficial substances in sufficient quantities. All of the above reduces the effectiveness of this phytocomplex.

It is known from RF patent No. 2027441, class A61K, 35/78, 1995, an agent for the prevention and treatment of malignant neoplasms, consisting of two tinctures and decoction, which include angelica root, calamus root, ephedra grass, plantain grass, ethyl alcohol (tincture 1), the root of the stepworm, the root of the marsh cinquefoil, the grass of ephedra, ethanol (tincture 2). Decoction - chaga (birch mushroom), ledum, St. John's wort, immortelle sandy, calendula, elecampane root, blueberry leaves, knotweed, horsetail, plantain, chicory, rose hips, bee honey.

The disadvantage of this drug is the insufficiently high effectiveness as an antitumor agent.

Known from the patent of the Russian Federation No. 2132197, class A61K 35/78 dietary supplement "Oleksin", used as an agent with antitumor and immunomodulating effects.

As a raw material for the preparation of this food additive, peach leaves are used, and the additive itself is a liquid extract.

This tool is taken as the closest analogue. Its disadvantages include the manifestation of beneficial properties inherent in only one plant component, which reduces the biological activity of the additive and narrows the range of its therapeutic and prophylactic possibilities.

The technical problem to which this invention is directed is to create an effective product based on plant materials that has increased biological activity and a wide range of therapeutic and prophylactic actions, including immunomodulating, antitumor, antioxidant and adaptogenic ones.

This is also the technical result for which this invention is intended, to which should also be added the expansion of the arsenal of biologically active drugs used for the prevention and treatment, mainly of oncological diseases.

Achieving the above technical result is ensured by the fact that the proposed dietary supplement contains an extract of the leaves and flowers of common peach (Persika vulgaris mill) and the extract of Stevia herb (Stevia rebaudiana Bertoni), mixed in a percentage ratio of 80:20.

Studies have shown that the leaves and flowers of common peach contain organic acids, tannin, carotenoids and flavonoids, including naringenin C ₁₂ H ₁₂ O ₅ , persicoside C ₂₂ H ₂₄ 0 ₁₁ , which have the following properties.

Karatonoids increase the overall resistance of the body, promote tissue regeneration, intensify the healing process of wounds, stimulate the immune system.

Organic acids with flavonoids have antiseptic, bactericidal and anti-inflammatory effects, reduce body intoxication, soothe pain, and reduce inflammation.

Naringenin and persicoside have both a direct effect on tumor cells and indirect.

Tannin has a capillary and hemostatic effect.

Stevia herb is a natural natural low-calorie sugar substitute, has a wide range of therapeutic properties. It contains a complex of vitamins, minerals, essential oils, flavonoids, tannins and other nutrients that determine the therapeutic and prophylactic aspects of its use. This herb has an antimicrobial and antifungal effect, promotes the excretion of metabolic products, toxins, salts of heavy metals from the body, has a general tonic effect, restores human strength after physical and nervous exhaustion, which is the result of a long illness. It is an indispensable tool for patients with diabetes.

Combining the Stevia herb extract in the appropriate proportion with the Oleksin extract allows you to create a biologically active drug with a wider range of therapeutic and prophylactic effects, while Stevia acts as a synergist with respect to the leaves of ordinary peach.

The extract from the leaves and flowers of common peach is made as follows.

Dry plant material is crushed and laid in a container in a proportion of 1 part by weight of plant material per 10 parts by weight of distilled water and extracted at a temperature of 95 ° -100 ° for one hour from the moment of boiling.

The extract obtained is filtered through a dense cloth, poured into a container and poured with a second portion of distilled water in the ratio of 1/3 to the original volume and extracted for 1/2 hour from the moment of boiling, after which the extract is drained, filtered, combined with the first and subjected to 3- boiling for hours to remove ballast substances, removing the foam and evaporating the extract at the same time. After boiling, the resulting substrate is cooled and settled at a temperature of plus three to five degrees Celsius for 24 hours. The precipitate formed is drained and centrifuged, the fraction purified from the precipitate is combined with the obtained extract and placed in a vacuum-evaporation unit and evaporated to a volume of 380-400 ml. The indicated volume is obtained from the calculation of one kilogram of dry plant material. To the extract obtained by the above method, as a preservative, 20% ethyl alcohol can be added in a ratio of 1: 1 for preservation.

The process of obtaining the extract from Stevia herb includes the preparation of plant materials, the extraction stage itself, the filtration stage and concentration.

When preparing raw materials, it is weighed and sent to grinding, which is produced on crushers or grinders of the cutting type. The particle size of the crushed raw materials should not exceed 3-6 mm.

The crushed raw material is loaded into the extractor and poured into the module in a ratio of 1:10. As a module, purified water is used. The extraction process is carried out at a temperature of 120 ° C and a pressure of 1.8 atmospheres for 2 hours. After the specified time, the resulting extract is poured from the extractor into a clean container and cooled to a temperature of 20-25 ° C. After that, the extract is filtered using Belting.

Concentration of the product is carried out on a vacuum evaporator at a temperature of 80 ° C and a pressure of 0.8 atm.

To obtain the finished product “Chrestevit”, the extract of the leaves and flowers of common peach and the extract of Stevia herb, obtained by the above methods, are mixed in a proportion of 80% of the extract of leaves and flowers of common peach and 20% of the extract of Stevia grass.

Thus obtained liquid product "Permistvit" has a dark brown color with a pleasant odor, a bitter-sweet taste, it is soluble in water, forming a solution of amber color.

The obtained biologically active food supplement is used 2-3 times a day, 6-12 drops per tablespoon of water 1 hour before a meal. Duration of admission is from 30 days to several years, with short breaks.

The study of the effectiveness of the biologically active food supplement “Perstevit” was carried out on a group of patients of different age categories and with various types of diseases, including oncological diseases and diabetes mellitus. The duration of the observations was several months.

The results of the observations indicate high therapeutic and prophylactic properties of the created drug and a wide range of manifestations of these properties.

Most patients showed positive dynamics in the treatment of the disease, increasing the body's immunity, and improving blood counts.

The biologically active food supplement “Perstevit” has an effect on the body as a whole, further enhances its own protective functions, with the help of which the body fights, in particular, with malignant tumors. It is convenient to use, it is not addictive. Its use reduces the period of postoperative rehabilitation, facilitates and prolongs the life of patients in the advanced stage of the disease.

Due to the wide range of its effects on the human body, the dietary supplement “Permevit” can be successfully used to treat various diseases, in particular pulmonary tuberculosis, diseases of the gastrointestinal tract, liver, colds, including the treatment of diabetes mellitus.

Claims (1)

A biologically active food supplement containing the extract of the leaves and flowers of common peach (Persika vulgaris mill), characterized in that it additionally contains an extract of Stevia herb (Stevia rebaudiana Bertoni), while in the finished product the extract of peach leaves and flowers and the extract of Stevia herb are related to percentage as 80:20.