RU2309765C2 - Composition of components for preparing balsam possessing general tonic effect - Google Patents

Abstract

FIELD: medicine, chemical-pharmaceutical and food processing industry.

SUBSTANCE: invention relates to producing liquid medicinal agents and biologically active supplements from vegetable raw. Composition of components for preparing balsam possessing the general tonic effect represents a mixture of natural honey and two aqueous-alcoholic tinctures. The first tincture is prepared from common marjoram herb, Saint-John's-wort herb, peppermint herb, common motherwort herb and purple coneflower herb, common oak bark, pot-marigold flowers and small-leaved linden flowers, blood-red haw-thorn fruits and wild rose fruits using 50% and 40% ethyl alcohol. The second tincture is prepared from common anise fruits and fragrant dill seeds, medicinal valerian rhizomes with roots, creeping wheat-grass and pink rosewort using 70% and 40% ethyl alcohol, and the composition contains components taken in the definite ratio and represents a 40% tincture. Composition is used in aims for normalization and improvement of human body functional state, in prophylaxis of catarrhal, infectious, cardiovascular, urolithiasis and cholelithiasis diseases and in diseases of upper respiratory airways. Balsam promotes to improving the basic metabolic processes, regulates and normalizes activity of digestive tract, enhances elimination of heavy metals, toxic substances from body, reduces symptoms of allergic diseases, accelerates regeneration and adaptability of tissue in transplantation.

EFFECT: improved, enhanced and valuable properties of composition.

1 tbl, 3 ex

Description

The invention relates to the chemical-pharmaceutical and food industries, in particular to the production of medicines and biologically active food additives from plant materials or in the distillery industry, in particular to the composition of ingredients for tincture and balm.

One of the ways to solve the problem of good nutrition is the inclusion in the diet of biologically active additives, which are natural components of biologically active substances that can activate the protective functions of the body.

A well-known composition of herbal ingredients for tincture-balm “Dert-Derman” containing St. John's wort, radiola pink (golden root), oregano, oak bark, rose hips, linden flowers, anise fruits, cloves, cinnamon, vanillin and honey (1). Balm tincture has a detoxifying, adaptogenic, anti-inflammatory and regulatory effect.

The closest technical solution is the composition of the ingredients for Agidel balsam, containing the root, oregano, birch buds, sweet clover, angelica, St. John's wort, cornflower, marigold, oak bark, buckthorn bark, coriander, linden flowers, peppermint, mother and - stepmother, motherwort, wormwood, pine buds, tansy, sushnitsa, bluehead, prickly tartar, yarrow, alder cones, cinnamon, apples, strawberries, chokeberry, rosehip, honey, orange oil, vanillin, propolis, special color, lemon and acid (2). The balm has a choleretic, diuretic, restorative and anti-sclerotic effect.

The disadvantages of these compositions is the low content of biologically active substances and a narrow range of preventive and restorative properties.

The objective of the invention is to increase the biological activity and expand the spectrum of the general strengthening effect of the composition.

The problem is solved in that the composition containing oregano, St. John's wort, calendula, oak bark, linden flowers, peppermint, motherwort, rosehip, honey and water-alcohol liquid, additionally contains purple coneflower, anise, hawthorn and dill fruits, rhizomes and roots valerian, wheatgrass and radiola rosea in the following ratio of ingredients, kg / 1000 gave:

Oregano grass 10-100 Hypericum perforatum herb 20-200 Peppermint Herb 8-80 Grass motherwort 1-10 Echinacea purpurea herb 5-50 Common oak bark 20-200 Calendula flowers 5-50 Small-leaved linden flowers 10-100 Fruits of anise 1-10 Fruits of hawthorn blood red 15-150 Fruits of dill odorous 1-10 Cinnamon Rose Hips 15-150 Rhizomes with Valerian officinalis roots 2-20 Rhizomes with Wheatgrass Roots 5-50 Rhizomes with the roots of a pink radiola 5-50 Natural honey 100-1000 ethyl alcohol 40% rest

The general strengthening effect of the composition is provided by a group of plants with certain quantitative values of the incoming ingredients.

Comparative analysis with the prototype shows that the claimed composition differs from the known additional effect on the body, which makes it possible to maintain the protective functions of the body at physiological boundaries.

- Echinacea purpurea contains polysaccharides, flavonoids, phenol carboxylic acids, polyacetylenes, essential oils, lectins, derivatives of caffeic acid, ascorbic acid, alkyl amides, minerals and other substances. These substances have a different effect on the human body in inflammatory and infectious diseases, activate cellular immunity, have antibacterial and antiviral activity, inhibit the development of tumors, accelerate tissue survival during transplantation, reduce the manifestation of allergic diseases, and promote the rapid healing of burns, wounds and ulcers.

- The fruits of the hawthorn blood red contain flavonoids, saponins, essential oil, sugars, carotenoids, tannins, triterpinic acids. Biologically active substances of hawthorn have an antiarrhythmic effect in functional disorders of cardiac activity, restore blood electrolytes and components of the coagulation and anticoagulation systems, increase blood circulation in the venous vessels of the heart and brain, lower high blood pressure, lower cholesterol and stabilize blood sugar, have antitumor effect.

- Fennel odorous fruits contain flavonoids, essential oil, carotene, ascorbic and folic acids, vitamins B ₁ , B ₂ , P and PP, sugars, potassium, calcium, phosphorus, iron salts and some trace elements. Due to the content of these substances, dill reduces blood pressure, dilates the coronary vessels, relaxes the tone of smooth muscles, regulates intestinal motility, increases the secretion of gastric juice, has an active choleretic and diuretic effect, and increases appetite.

- The fruits of ordinary anise contain fatty oil, protein substances, furocoumarins and essential anise oil, which includes anethole, anisic aldehyde, anisic ketone, anisic acid, methyl havicol. Anise fruits are used as an aromatic, analgesic, anti-inflammatory, antispasmodic, secretolytic, diuretic and gastrointestinal stimulant, as well as to stimulate appetite and improve sleep.

- The main active ingredient in the roots and rhizomes of the pink radiola are cinnamoyl glycosides rosavin and rosavidin, the phenol alcohol tyrosol and its glycoside salidroside (radioloside). In addition, they contain tannins, anthraquinones, oxycumcerins, flavonoids, essential oils, phenolic acids, fats, waxes, sterols, organic acids, etc. Pharmacological and clinical studies of pink radiola have established its stimulating, antihypnotic, antioxidant and antihypoxic effects, as well as anti-tuberculosis and antitumor activity, the ability to significantly increase sexual potency and enhance the body's resistance to adverse environmental influences.

- Creeping wheatgrass roots and rhizomes contain the phenolic compound Aveline, fructan tricitin, essential oils, malic acid, levulose, fructose, mannitol, vitamin C, carotene and other substances. Due to the content of these substances, wheat grass is used as a diuretic, painkiller, anti-inflammatory, emollient, diaphoretic and expectorant.

- The roots and rhizomes of valerian officinalis contain valerian oil, alkaloids valerin and hatinin, valepatriotes (acetylated iridoids), phenolic compounds, organic and other acids, resin and tannins. These substances, acting comprehensively on the body, weaken cramps, reduce excitement, have an inhibitory effect on the systems of the medulla oblongata and midbrain, increase the functional mobility of cortical processes, improve coronary blood flow, increase secretion of the glandular apparatus of the gastrointestinal tract, bile secretion, and relax smooth muscle spasms, restore sexual potency.

The composition in the amount of 1000 l is prepared as follows: take oregano herbs 1-10 kg, St. John's wort 2-20 kg, mint 0.8-8 kg, motherwort 0.1-1 kg, echinacea 0.5-5 kg, oak bark 2 -20 kg, flowers of calendula 0.5-5 kg and linden 1-10 kg, fruits of hawthorn 1.5-15 kg and rose hips 1.5-15 kg, chopped and poured 360 l of water-alcohol liquid with a strength of 50 vol.% and insist 10 days with stirring 3 times a day. Then make the first discharge of infusion. The remaining ingredients are re-poured 360 l of water-alcohol liquid with a strength of 40 vol.% And insist 5 days with stirring 3 times a day.

Separately, an infusion of seeds, rhizomes and roots is prepared. Take the fruits of anise 0.1-1 kg and dill 0.1-1 kg, rhizomes with valerian roots 0.2-2 kg, wheat grass 0.5-5 kg and pink radiola 0.5-5 kg, chopped and poured 45 l of water-alcohol liquid with a strength of 70 vol.% and insist 12 days with stirring 3 times a day. Then make the first discharge of infusion. The remaining ingredients are re-filled with 45 l of water-alcohol liquid with a strength of 40 vol.% And insisted for 6 days with stirring 3 times a day.

Blending is performed by combining the first and second plums of herbs and fruits in one vessel, and then 50-100 kg of honey and the required amount of purified water are added to the first and second plums of the infusion of seeds, rhizomes and roots to obtain a fortress of 40 vol.%. The blend is stirred, kept for 5-7 days, then filtered and transferred to the bottling.

Example 1. For the preparation of 1000 l of semisweet tincture with a strength of 40 vol.%, Containing extractives 6.2 g / 100 cm ³ , sugar 4.2 g / 100 cm and an acid concentration of 0.05 g / cm ³ , use the following ingredients, kg:

Oregano grass one Hypericum perforatum herb 2 Peppermint Herb 0.8 Grass motherwort 0.1 Echinacea purpurea herb 0.5 Common oak bark 2 Calendula flowers 0.5 Small-leaved linden flowers one Fruits of anise 0.1 Fruits of hawthorn blood red 1,5 Fruits of dill odorous 0.1 Cinnamon Rose Hips fifteen Rhizomes with Valerian officinalis roots 0.2 Rhizomes with Wheatgrass Roots 0.5 Rhizomes with the roots of a pink radiola 0.5 Natural honey fifty Liquid alcohol rest

Example 2. For the preparation of 1000 l of balm with a strength of 40 vol.%, Containing extractive substances 11.5 g / 100 cm ³ , sugar 9.2 g / 100 cm ³ and an acid concentration of 0.08 g / cm ³ , use the following ingredients, kg:

Oregano grass 10 Hypericum perforatum herb twenty Peppermint Herb 8 Grass motherwort one Echinacea purpurea herb 5 Common oak bark twenty Calendula flowers 5 Small-leaved linden flowers 10 Fruits of anise one Fruits of hawthorn blood red fifteen Fruits of dill odorous one Cinnamon Rose Hips fifteen Rhizomes with Valerian officinalis roots 2 Rhizomes with Wheatgrass Roots 5 Rhizomes with the roots of a pink radiola 5 Natural honey one hundred Liquid alcohol rest

Example 3. To prepare 1000 l of biologically active food additives with a strength of 40 vol.%, Use the following ingredients, kg:

Oregano grass 5 Hypericum perforatum herb 10 Peppermint Herb four Grass motherwort 0.5 Echinacea purpurea herb 2,5 Common oak bark 10 Calendula flowers 2,5 Small-leaved linden flowers 5 Fruits of anise 0.5 Fruits of hawthorn blood red 7.5 Fruits of dill odorous 0.5 Cinnamon Rose Hips 7.5 Rhizomes with Valerian officinalis roots one Rhizomes with Wheatgrass Roots 2,5 Rhizomes with the roots of a pink radiola 2,5 Natural honey 75 ethyl alcohol 40% rest

In all three examples, a composition is obtained with the following organoleptic properties:

- color - brown with a red tint,

- taste - bitter-spicy,

- aroma - complex, rounded without highlighting the aroma of the individual ingredients.

The ingredients included in the composition are selected mainly for similar, complementary effects, but acting on different parts of the body's self-regulation, therefore their total biological activity significantly exceeds the sum of the effects of each of them individually, providing the composition with qualitatively new properties.

The composition is a good adaptogen - a means of stabilizing nervous processes, regulating the processes of excitation and inhibition, increasing physical and mental performance and resistance of the body to adverse external influences due to the presence of biologically active substances in it: hypericum, oregano, dill, anise, hawthorn, valerian, flowers of calendula and linden (containing flavonoids, terpenoids, amino acids, carotenoids, saponins, vitamins, etc.).

The composition increases the body's resistance to pathogens of infectious diseases and activates cellular immunity.

The composition has a multilateral effect on the body in inflammatory diseases. It is especially effective in the treatment of inflammatory diseases of the urinary tract, urinary organs and gastrointestinal tract, with peptic ulcer of the stomach and duodenum, colitis and enterocolitis.

The composition helps to improve metabolic processes that increase the excretion of uric acid salts from the body through urine due to the St. John’s Wort, mint, anise, dill, wheatgrass and linden flowers that are part of the biologically active substances. These ingredients have a positive effect on water-salt metabolism, preventing the formation of edema, and contribute to their elimination, enhancing the excretion of water and salts from the body.

Due to the presence of mint, dill and wheatgrass in the composition, the composition increases appetite.

A well-balanced composition of ingredients allows it to be used after serious illness during the period of convalescence.

The biologically active substances of the plants included in the composition participate in the formation of organoleptic properties, so the harmonious combination of herbs, flowers, fruits, roots and rhizomes with honey gives it a peculiar aroma and harmoniously folded taste.

On four groups formed from volunteers, tests were conducted on the general strengthening effect of the composition (example 1, example 2, example 3).

1 group of volunteers consisted of 10 people, male, age 25-40 years, involved in sports (soccer players) - composition of example No. 1,

2 group of volunteers consisted of 10 people (5 women, 5 men), age 25-40 years, employed in production, composition of example No. 2,

3 group of volunteers consisted of 10 people (5 women, 5 men), the age of 25-40 years, engaged in mental work composition of example No. 3,

The 4th group of volunteers consisted of 10 people (5 women, 5 men), the age of 25-40 years employed in production - control.

As a control in the 4th group, Agidel balm was used, kindly provided by V. Yusupov. Reception time - autumn, off-season, switch to winter time.

Volunteers took compositions No. 1, 2, 3 and Agidel balm during the autumn calendar month (November 2006) at a dose of 1 tablespoon (20 ml) 3 times a day with meals. Condition monitoring was carried out daily in the Diagnostic Center of CJSC EKOlab and was recorded in the workbook according to the selected criteria: general fatigue, working capacity, blood pressure, sleep. After the course of application, the obtained observation results were summarized and analyzed by specialists. Digitally, the results are shown in the table:

Selected option % of group members Group 1 Group 2 Group 3 Group 4 Reduced General Fatigue 75 78 75 65 Uptime 85 82 80 72 Pressure normalization 85 75 70 79 Sleep normalization 92 78 85 72 Increased vitality 85 92 85 65 Increased resistance to ARI and ODS 87 76 85 66

An experimental study of functional activity and evaluation of effectiveness showed that the compositions obtained have a general strengthening, adaptogenic, anti-inflammatory, antispasmodic and analgesic effect. They can be used to normalize and improve the functional state and protective functions of the human body.

These compositions help to improve the basic metabolic processes, regulate and restore the activity of the gastrointestinal tract, enhance the excretion of heavy metals, toxic substances, water and salts from the body, lower cholesterol and stabilize blood sugar, increase appetite.

The composition contains affordable, inexpensive plants, widely distributed in ecologically clean regions of Russia, which simplifies their collection and harvesting. The proposed composition can be used as an additive to tea, coffee, mineral water, soft drinks and vodka products in a small dose, chosen according to taste.

Sources of information used:

1. Auto RF № 2085580, class 6 s12G 3/06, А61К 35/78, 1995.

2. Auto USSR No. 863633, class c12G 3/06, 1979.

Claims (1)

The composition of the ingredients for the preparation of a balm with a restorative effect, characterized in that it is a mixture of natural honey and two water-alcohol tinctures of plant materials, the first of which is obtained from herbs of oregano, St. John's wort, peppermint, motherwort and Echinacea purpurea, bark of common oak, calendula and linden linden flowers, blood-red hawthorn berries and cinnamon rose hips with the use of 50 and 40% ethyl alcohol, and the second and h fruits of ordinary anise and odorous dill, rhizomes with the roots of Valerian officinalis, wheat grass creeping and Rhodiola rosea using 70 and 40% ethyl alcohol, while the composition contains ingredients in the following ratio of ingredients, kg / 1000 dal: marjoram grass 10-100 Hypericum perforatum herb 20-200 peppermint herb 8-80 grass motherwort 1-10 Echinacea purpurea herb 5-50 common oak bark 20-200 calendula flowers 5-50 small-leaved linden flowers 10-100 fruits of anise 1-10 the fruits of hawthorn blood red 15-150 fruits of dill odorous 1-10 rosehips of cinnamon 15-150 rhizomes with valerian roots 2-20 medicinal rhizomes with roots of wheat grass creeping 5-50 rhizomes with the roots of Rhodiola rosea 5-50 natural honey 100-1000 ethyl alcohol 40% rest