RU2355383C2 - Косметическое средство на основе коллагеназы микробного происхождения - Google Patents
Косметическое средство на основе коллагеназы микробного происхождения Download PDFInfo
- Publication number
- RU2355383C2 RU2355383C2 RU2007123728/15A RU2007123728A RU2355383C2 RU 2355383 C2 RU2355383 C2 RU 2355383C2 RU 2007123728/15 A RU2007123728/15 A RU 2007123728/15A RU 2007123728 A RU2007123728 A RU 2007123728A RU 2355383 C2 RU2355383 C2 RU 2355383C2
- Authority
- RU
- Russia
- Prior art keywords
- cosmetic
- skin
- enzyme preparation
- triethanolamine
- distilled
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- 108010013295 Microbial collagenase Proteins 0.000 title claims description 4
- 102000004190 Enzymes Human genes 0.000 claims abstract description 18
- 108090000790 Enzymes Proteins 0.000 claims abstract description 18
- 229940088598 enzyme Drugs 0.000 claims abstract description 18
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims abstract description 8
- DCXXMTOCNZCJGO-UHFFFAOYSA-N Glycerol trioctadecanoate Natural products CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 claims abstract description 8
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 8
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 claims abstract description 8
- 235000011187 glycerol Nutrition 0.000 claims abstract description 7
- 230000037303 wrinkles Effects 0.000 claims abstract description 6
- 238000009499 grossing Methods 0.000 claims abstract description 4
- 230000000845 anti-microbial effect Effects 0.000 claims abstract 2
- 230000004936 stimulating effect Effects 0.000 claims abstract 2
- 239000000126 substance Substances 0.000 claims abstract 2
- 239000002537 cosmetic Substances 0.000 claims description 23
- 239000002253 acid Substances 0.000 claims description 10
- 239000002304 perfume Substances 0.000 claims description 8
- 239000004006 olive oil Substances 0.000 claims description 7
- 235000008390 olive oil Nutrition 0.000 claims description 7
- 239000004166 Lanolin Substances 0.000 claims description 6
- 235000019841 confectionery fat Nutrition 0.000 claims description 6
- 229940039717 lanolin Drugs 0.000 claims description 6
- 235000019388 lanolin Nutrition 0.000 claims description 6
- QOSMNYMQXIVWKY-UHFFFAOYSA-N Propyl levulinate Chemical compound CCCOC(=O)CCC(C)=O QOSMNYMQXIVWKY-UHFFFAOYSA-N 0.000 claims description 5
- 150000004702 methyl esters Chemical class 0.000 claims description 5
- 239000000490 cosmetic additive Substances 0.000 claims description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 2
- 230000003020 moisturizing effect Effects 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 239000000203 mixture Substances 0.000 abstract description 15
- 108060005980 Collagenase Proteins 0.000 abstract description 6
- 102000029816 Collagenase Human genes 0.000 abstract description 6
- 229960002424 collagenase Drugs 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 102000035092 Neutral proteases Human genes 0.000 abstract description 4
- 108091005507 Neutral proteases Proteins 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract description 4
- 230000000813 microbial effect Effects 0.000 abstract description 2
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 239000000686 essence Substances 0.000 abstract 1
- 239000003925 fat Substances 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 22
- 239000006071 cream Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 4
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 3
- 108090000145 Bacillolysin Proteins 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000000284 extract Substances 0.000 description 3
- 230000003480 fibrinolytic effect Effects 0.000 description 3
- 230000003282 necrolytic effect Effects 0.000 description 3
- 210000000434 stratum corneum Anatomy 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 206010013786 Dry skin Diseases 0.000 description 2
- 240000000950 Hippophae rhamnoides Species 0.000 description 2
- 235000003145 Hippophae rhamnoides Nutrition 0.000 description 2
- 102000016387 Pancreatic elastase Human genes 0.000 description 2
- 108010067372 Pancreatic elastase Proteins 0.000 description 2
- 102000035195 Peptidases Human genes 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- 241000241413 Propolis Species 0.000 description 2
- 239000004365 Protease Substances 0.000 description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 2
- FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 description 2
- -1 carboxypepsidase Proteins 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 239000003974 emollient agent Substances 0.000 description 2
- 239000010645 fir oil Substances 0.000 description 2
- 229940069949 propolis Drugs 0.000 description 2
- 230000003716 rejuvenation Effects 0.000 description 2
- 230000001235 sensitizing effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000001256 tonic effect Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 235000019155 vitamin A Nutrition 0.000 description 2
- 239000011719 vitamin A Substances 0.000 description 2
- 229940045997 vitamin a Drugs 0.000 description 2
- 208000003643 Callosities Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 102000002704 Leucyl aminopeptidase Human genes 0.000 description 1
- 108010004098 Leucyl aminopeptidase Proteins 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 241000187389 Streptomyces lavendulae Species 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000009535 clinical urine test Methods 0.000 description 1
- 230000003366 colagenolytic effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000008278 cosmetic cream Substances 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- POLCUAVZOMRGSN-UHFFFAOYSA-N dipropyl ether Chemical class CCCOCCC POLCUAVZOMRGSN-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000003527 fibrinolytic agent Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 150000004508 retinoic acid derivatives Chemical class 0.000 description 1
- 235000020944 retinol Nutrition 0.000 description 1
- 229960003471 retinol Drugs 0.000 description 1
- 239000011607 retinol Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 230000037393 skin firmness Effects 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000002537 thrombolytic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 241001446247 uncultured actinomycete Species 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 229930007845 β-thujaplicin Natural products 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2007123728/15A RU2355383C2 (ru) | 2007-06-26 | 2007-06-26 | Косметическое средство на основе коллагеназы микробного происхождения |
| PCT/RU2007/000522 WO2009002208A1 (fr) | 2007-06-26 | 2007-09-27 | Produit cosmétique microbiotique à base de collagénase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2007123728/15A RU2355383C2 (ru) | 2007-06-26 | 2007-06-26 | Косметическое средство на основе коллагеназы микробного происхождения |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2355383C2 true RU2355383C2 (ru) | 2009-05-20 |
Family
ID=40185853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007123728/15A RU2355383C2 (ru) | 2007-06-26 | 2007-06-26 | Косметическое средство на основе коллагеназы микробного происхождения |
Country Status (2)
| Country | Link |
|---|---|
| RU (1) | RU2355383C2 (fr) |
| WO (1) | WO2009002208A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114533584B (zh) * | 2022-04-21 | 2023-12-19 | 加来(济南)生活科技有限公司 | 一种胶原蛋白酶抗皱面霜 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2045262C1 (ru) * | 1992-09-02 | 1995-10-10 | Светлана Петровна Шумиченко | Средство для укладки волос |
| RU2089177C1 (ru) * | 1994-02-03 | 1997-09-10 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Средство для ухода за кожей |
| RU2096032C1 (ru) * | 1994-09-27 | 1997-11-20 | Акционерное общество закрытого типа "Химико-биологическое объединение при РАН" | Косметическое средство |
| RU2110987C1 (ru) * | 1994-10-06 | 1998-05-20 | Производственно-коммерческая фирма "Линда" | Косметический крем |
| RU2141310C1 (ru) * | 1997-11-28 | 1999-11-20 | Открытое акционерное общество "СПб-Технология" | Активное начало косметического средства и косметическое средство (варианты) |
| WO2000078332A2 (fr) * | 1999-06-18 | 2000-12-28 | Jon Bragi Bjarnason | Proteinases de serine de poisson et leur utilisation pharmaceutique et cosmetique |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2045261C1 (ru) * | 1991-05-07 | 1995-10-10 | 1-я Московская медицинская академия им.И.М.Сеченова | Косметическое средство для регенерации увядающей кожи |
-
2007
- 2007-06-26 RU RU2007123728/15A patent/RU2355383C2/ru not_active IP Right Cessation
- 2007-09-27 WO PCT/RU2007/000522 patent/WO2009002208A1/fr not_active Ceased
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2045262C1 (ru) * | 1992-09-02 | 1995-10-10 | Светлана Петровна Шумиченко | Средство для укладки волос |
| RU2089177C1 (ru) * | 1994-02-03 | 1997-09-10 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Средство для ухода за кожей |
| RU2096032C1 (ru) * | 1994-09-27 | 1997-11-20 | Акционерное общество закрытого типа "Химико-биологическое объединение при РАН" | Косметическое средство |
| RU2110987C1 (ru) * | 1994-10-06 | 1998-05-20 | Производственно-коммерческая фирма "Линда" | Косметический крем |
| RU2141310C1 (ru) * | 1997-11-28 | 1999-11-20 | Открытое акционерное общество "СПб-Технология" | Активное начало косметического средства и косметическое средство (варианты) |
| WO2000078332A2 (fr) * | 1999-06-18 | 2000-12-28 | Jon Bragi Bjarnason | Proteinases de serine de poisson et leur utilisation pharmaceutique et cosmetique |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009002208A1 (fr) | 2008-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20110627 |