RU2234241C2 - Method and device for processing pulse wave signals, method for measuring pulse wave and method for processing parameter-measuring signals reflecting condition of organism organs and/or systems - Google Patents

Abstract

FIELD: medicine; medical engineering.

SUBSTANCE: method involves producing electric signal corresponding to pulse wave under measurement by means of transducer set on body surface on a vein, adjusting amplitude-frequency characteristic of the produced electric signal to build electric signal of prescribed shape as a line in a group of sequential sinusoid half-waves of measured pulse wave period. The first and the second sinusoid half-waves amplitudes are greater than the following sinusoid half-waves amplitudes of pulse wave under measurement. Comparison analysis of amplitude-frequency characteristics of electric signal of prescribed shape is carried out to set diagnosis. When adjusting amplitude-frequency characteristic of the produced electric signal, electric signal of prescribed shape is built. The signal is composed of two half-periods of pulse wave under measurement equal in duration. A group of five sequential sinusoid half-waves is included into the first half-period of pulse wave under measurement of which the first, the third and the fifth sinusoid half-wave are positive half-waves and the second, the fourth and the sixth ones are negative half-waves. Power of prescribed shape electric signal and/or powers of signal components are determined from amplitude-frequency characteristics and comparison analysis is carried out for setting diagnosis by comparing powers of signal components of pulse wave under measurement to component powers of standard shape pulse wave signal corresponding to normal organism organs and/or systems condition and/or by comparing powers of signal components of pulse wave under measurement to each other. Methods for measuring pulse wave and parameters describing organism organs and/or systems condition involve applying deviation matrix and device usable for implementing the methods.

EFFECT: high accuracy and reliability of measurements and diagnosis.

27 cl, 9 dwg

Description

The invention relates to medicine, namely to the measurement of a pulse wave for diagnostic purposes. The invention also relates to the field of reflexology.

A device for recording a pulse containing converters is known, each of which includes a housing, a light source, a photodetector, a rod with a flag and a working tip. The transducers bring to the patient’s hand, metered pressing of the working tip to the artery in the desired areas. When the rod moves under the action of a pulse wave of an artery, the flag changes the luminous flux from the light source to the photodetector, the photodetector converts the luminous flux into an electric signal, which is transmitted to the measuring device and recorder [SU 736955, 1980]. A device for determining the pulse, containing converters, each of which contains a voltage follower, two stationary electrodes and a movable electrode located between the stationary electrodes, and also contains a pilot and a rod [RU 2077259 C1, 1997]. The transducers with the help of straps are fixed on the arm above the radial artery near the wrist, and the pelots are metered against the artery. When the pilot with the rod moves under the action of a pulse wave, the movable electrode moves between the stationary ones, and the electric capacitances formed by these electrodes change due to a change in the distance between them. Pulse-modulated alternating voltage is applied to the voltage follower input, which ensures undistorted transmission of the electrical signal to the stationary measuring module. You can select the range of displacements to obtain any triangular linearity of the conversion of displacements into an electrical signal. Next, the electrical signal from the converters is fed to the input of the measuring module, where the signal is detected, amplified and digitized, after which the received information is processed in a computer for the purpose of making a diagnosis. The device allows for the integral express diagnostics of the human body using the methods described in Tibetan medical texts. The presence in the known devices of mechanically moving rubbing parts, which also have inertia, does not allow to achieve high accuracy of pulse wave measurement, and, as a result, the accuracy and reliability of the diagnosis are reduced.

A known method for the differential diagnosis of lung diseases by recording and recording a sphygmographic signal from the patient's radial artery using a photoelectric sensor [RU 2100009 C1, 1997]. Characteristic points of single oscillations are distinguished in the signal, the amplitude and time parameters of these pulse wave points are determined, dynamic series are formed that reflect the dependence of the found parameters on the period number, a spectral analysis of the formed series is carried out, criterion P is calculated, the value of which is used to diagnose. A known method of measuring blood pressure in a blood vessel, which consists in the fact that the pressure sensor is pressed against the skin of the patient above the blood vessel, the change in the gap between the membrane and the end of the fiber-optic transducer probe is measured, the change in value is converted into a change in reflected light flux proportional to the change pressure in a blood vessel, convert the magnitude of the change in the reflected light flux into a pulse wave, according to which the program diagnoses cardiac vascular system and stress state of the body [RU 2176387 C1, 2001]. A known apparatus and method for a non-traumatic diagnosis of cardiovascular and related disorders [WO 99/57674 A1, 1999]. The system processes the correspondence between the dynamics of the arterial pulse wave circuit, fluctuations in blood pressure, and related illness. The system includes an input module with a pressure sensor, a signal receiver, and a processing module. The input module uses a pressure sensor. The signal receiver amplifies, digitizes and normalizes the arterial signal of pulse fluctuations in blood pressure. In the processing module, the signal is analyzed by amplitude-frequency characteristics. Known methods and devices have a narrow diagnostic focus.

A known method for diagnosing the state of a biological object, including converting a biological pulse sequence into an electrical pulse sequence, followed by measuring the pulse parameters, which evaluate the state of the biological object [RU 2118121 C1, 1998]. The method is based on the analysis of the average propagation velocity of the pulse wave in various parts of the large and small circles of blood circulation. A device for implementing the method comprises optoelectronic converters, electric pulse train, a frequency generator, NAND key logic, a discriminator-generator of the phase relation of the fronts of the two compared pulses, a control command generator, a frequency counter, a memory register, an indicator. The reliability of the diagnostic results obtained using this method is not high enough, because the average velocity of the pulse wave does not reliably reflect the state of many organs and the whole organism.

A device for active diagnostics is known, which contains a complex unit of a peripheral pulse sensor, including an optocoupler unit with a matching stage, and a complex hardware-software unit, including blocks for recording a pulse wave, analyzing the quality of a pulse wave, controlling operating modes, and the memory of classification signs of pulse wave classes, memory normative data, definition of private and generalized indicators and visual information output, as well as a control panel, which also contains a comprehensive art sensor unit pressure and integrated block actuators [RU 9577 U1, 1999]. Similar diagnostic devices are also known for making a pulse wave diagnosis [WO 99/09884 A1, 1999; WO 99/26529 A1, 1999]. Known devices do not allow for an accurate diagnosis, because empirical normative data are used for analysis.

As a prototype of the selected well-known pulsodiagnostic device and a method of measuring a pulse wave using it [US 5381797 C1, 1995]. The pulse diagnostic device includes: an amplitude-frequency pulse wave sensor adapted to be installed on the inside of the wrist at points Cun, Guan and Chi on a vein to generate a pulse wave signal; means for adjusting the amplitude-frequency characteristics of the pulse wave sensor to obtain a pulse wave signal of a prescribed shape containing a group of characteristic half-waves; a processing module of a pulse wave signal connected to a pulse wave sensor for processing a group of characteristic half-waves, the processing module including an amplifier, an analog-to-digital converter, a pulse waveform analyzer and a recorder. The means for adjusting the amplitude-frequency characteristic is intended to generate a pulse wave signal containing the first to fifth characteristic sinusoidal half-waves following one after the other, the first half-wave being positive, the second negative, with an amplitude almost equal to the amplitude of the first half-wave, the third and fourth half-waves positive with approximately equal amplitudes, which are less than the amplitude of the first half-wave, and the fifth half-wave is positive with an amplitude of not more than than the amplitude of the third and fourth half-waves, and the duration of the fifth half-wave is approximately equal to the total duration of the first four half-waves. In particular, the device includes a microphone used as a pulse wave sensor, and an air chamber open from the input side, which is placed in front of the microphone and which is used as a means of correcting the amplitude-frequency characteristic. The pulse waveform waveform analyzer includes a parameter calculator that calculates the maximum amplitudes and durations of the first and second half waves, calculates the maximum amplitudes of the third and fourth half waves, determines the first relation between the maximum amplitudes of the fourth and third half waves, and determines the second ratio between the durations of the entire group of half waves and the fifth wave . A method for measuring a pulse wave using the described device, which includes an electric pulse wave sensor and a recorder, involves the following operations: manually pressing the pulse wave sensor to the wrist at points Cun, Guan and Chi, reflecting the state of internal organs and systems; adjustment of the pressing force to position the pulse wave sensor in the position related to the measurement of surface and / or deep heart rate, and this adjustment is performed to maximize the magnitude of the pulse amplitude of the wave signal, perceived visually in the recorder; correction of the amplitude characteristic of the pulse wave signal from the pulse wave sensor. To diagnose the state of organs and systems of the body, the amplitudes and durations of at least one characteristic half-wave are compared with the amplitude and duration of at least one other half-wave. The idea of the structure of the pulse wave in the known method was obtained from experience and is not accurate enough. The system of interpretation of parameters is more empirical in nature, which makes it difficult to establish a connection with pulse parameters and assessments of the human condition that have developed in classical eastern medicine.

Known methods for diagnosing the state of the body, based on measuring the parameters of reflex points (BAP), reflecting the balance of the internal energy of the body, based on the canons of classical eastern medicine.

A known method for determining the functional state of the body is that they measure the electrical conductivity of the skin in the area of the projection of the Yin and Yang components of the white chakras on the hands, the values of which are recorded separately [RU 2137458 Cl, 1999]. A table is composed of two parts, seven columns each. Build a "physiological corridor", connect the left and right values, getting diagrams. By the location of the values of the Yin components within, above or below the physiological boundaries, the norm, excess or deficiency of the six basic energies and, accordingly, the norm, hyper- or hypofunction of organs and systems associated with them are determined. The mutual arrangement of "physiological corridors" assesses the general psycho-vegetative state. By the presence of an excess or lack of basic energies of Yan-components, the prevailing psycho-emotional states are revealed and, comparing them with the most pronounced hypo- or hyperfunctional states of the organs, psychosomatic complexes are established. Then, the Bel Chakra is diagnosed with the most pronounced excess or deficiency of the main energy, measuring the electrical conductivity of the branch energies. The values are entered into a table of six columns. Identify the impaired function of the body in excess or lack of industry energy. The norm is considered the values of the parameters of the “physiological corridor”, determined empirically, therefore, the diagnosis is relative and, therefore, unreliable.

As a second prototype, a device and method for reflexological measurements were selected, which standardizes and classifies a new measuring module [WO 01/12062 A1, 2001]. Reflexological measurements are carried out using a measuring sensor, the electrical signals from which are transformed into a matrix of the FTDB format (Ferraro-Tkachenko database) through the transduction system, which reflects all potential values of the measured parameters, and the organs are viewed using a computer, equipped with appropriate software. In the conversion, electrical signals are structured into a combination and configured in sequences and / or comparative sequences for diagnosis. As measured parameters of the BAT, BAT conductivity is used, which reflects the state of the internal energies of the channels in accordance with the concepts of classical oriental medicine, and the possibility of reflexological measurements of electrical signals of various shapes, durations and types is also provided. Configured sequences are represented as two branches of a sinusoidal graph - positive and negative. For diagnosis, a sinusoidal graph can be divided into several phases, and a comparative analysis can be carried out in phases. The used matrix graph does not adequately reflect the balance of the internal energies of the body, which does not allow a reliable diagnosis.

Technical tasks to be solved by the group of inventions: improving the accuracy of the pulse wave measurement and the reliability of the measurement results; improving the accuracy of diagnosing the state of the body by measured pulse wave or by measured parameters in reflex BAT.

According to the first variant of the method for diagnosing the state of organs and / or body systems by the amplitude-frequency characteristic of a pulse wave, an electrical signal corresponding to the measured pulse wave is generated using a sensor that is mounted on the surface of the body above a vein or artery, and the amplitude-frequency characteristic of the generated electric is adjusted signal to receive an electrical signal of the prescribed form in the form of a line from a group of consecutive sinusoidal half-waves of the period of the measured pool a wave, and the amplitudes of the first and second sinusoidal half-waves are greater than the amplitudes of subsequent sinusoidal half-waves of the period of the measured pulse wave, and a comparative analysis of the amplitude-frequency characteristics of the electrical signal of the prescribed form for diagnosis is performed. What is new is that when adjusting the amplitude-frequency characteristics of the generated electrical signal, an prescribed signal is obtained consisting of two equal half-periods of the measured pulse wave, and in the first half-period of the measured pulse wave include a group of five consecutive sinusoidal half-waves, of which the first, the third and fifth sinusoidal half-waves are positive half-waves, and the second and fourth sinusoidal half-waves are negative n bastards. According to the obtained amplitude-frequency characteristics of the electric signal of the prescribed form, its energy is determined corresponding to the energy of the period of the measured pulse wave, because the generated electrical signal itself corresponds to the measured pulse wave and / or energy of the components of the electrical signal of the prescribed form into which it can be decomposed, for example, as will be shown below. After that, a comparative analysis is performed to make a diagnosis by comparing the energies of the components of the signal of the measured pulse wave with the energies of the components of the reference waveform of the pulse wave corresponding to the normal state of organs and / or systems of the body, and / or by comparing the energies of the components of the signal of the measured pulse wave with each other. The determination of the indicated energies of the electrical signal of the prescribed form for a period from t ₁ to t ₂ , which includes the half-waves of the signal of the prescribed form indicated by the applicant, is not particularly difficult with relatively simple, for example, software tools, since for the field of measurement of electrical quantities, the energy received in the receiver over a period of time from t ₁ to t ₂ is expressed by the integral:

where u is voltage, i is current (see G.I. Atabekov. Theoretical Foundations of Electrical Engineering. Part 1. - M .: Energy, 1970, p.22), and, based on the definition of the integral, it can be calculated as the area, limited by the line from the group of consecutive sinusoidal half-waves of the period and the time axis of the abscissa.

It is better when in the second half-period of the measured pulse wave include a group of consecutive sinusoidal half-waves, the amplitude of each of which is less than the amplitude of any of the first five sinusoidal half-waves of the first half-period of the measured pulse wave.

The sensor can be mounted on the inside of the wrist at the points of Cun, or Guan, or Chi.

An electrical signal corresponding to the measured pulse wave can be generated using an acoustic sensor that is mounted and pressed over a vein or artery, and the strength and direction of compression are adjusted until a stable electrical signal is obtained.

As a reference pulse wave, it is better to use a pulse wave in the form of a signal in the form of a group of successive reference half-waves that vary according to the sine law, and it is better when a pulse wave is used as a reference pulse wave, the signal energy for a period of which is equal to the signal energy of the prescribed shape of the measured pulse wave over a period. A group of sequential reference half-waves, changing according to the sine law, can be represented as a line corresponding to its signal, so that the amplitudes of the first and second reference half-waves of the first half-period of the reference pulse wave, equal to the half-period of the measured pulse wave, are equal to each other and more than the amplitudes of the third, fourth and the fifth reference half-waves equal to each other, the first, third and fifth reference half-waves being positive half-waves, and the second and fourth reference half-waves being negative half-waves, and in the second half-period of the reference pulse wave include a group of consecutive decaying reference half-waves, the amplitude of each of which is less than the amplitude of any of the first five reference half-waves of the first half-period of the reference pulse wave. The indicated line corresponding to the signal of the reference pulse wave is decomposed into even and odd components in the form of two lines, each of which consists of a group of consecutive half-waves, and the sum of the ordinates of the lines of even and odd components with the same abscissa is equal to the ordinate of the signal line of the reference pulse wave with the same the abscissa, moreover, in the first half-period, the lines of even and odd components coincide, and their ordinates are less than the corresponding ordinates of the signal line of the reference pulse wave and coincide in sign, in the second half-period, the line of the odd component is obtained by plotting the line opposite in the ordinate and the symmetric line of the odd component of the first half-period relative to the point on the abscissa axis corresponding to the middle of the period, the line of the odd component passing through this point and the line of the even component of the second half-period a line symmetrical to the line of the even component of the first half-period relative to the axis parallel to the ordinate axis and passing through the midpoint of the period on the axis abscissa.

The signal line of the prescribed shape of the measured pulse wave can also be decomposed into even and odd components in the form of two lines, each of which consists of a group of consecutive half-waves, and the sum of the ordinates of the lines of even and odd components with the same abscissa is equal to the ordinate of the signal line of the prescribed shape with the same abscissa moreover, in the first half-period of the measured pulse wave include groups of five consecutive derivatives of half-waves, and the amplitudes of the first and second derivatives of half-waves are greater than the amplitudes of the subsequent half-wave derivatives of the first half-wave of the pulse wave, the first, third, and fifth derivatives of the half-waves are positive half-waves, and the second and fourth derivatives of the half-waves are negative half-waves, in the second half-cycle, the line of the even component is obtained by constructing a line symmetrical to the line of the even component of the first half-period relative to the axis, parallel to the ordinate axis and passing through the midpoint of the period on the abscissa, and the line of the odd component of the second half period get n Then we draw a line symmetrical to the line of the odd component of the first half-period with respect to a point on the abscissa axis corresponding to the middle of the period, and the line of the odd component passes through this point.

The period of the measured pulse wave can be divided into several phases, after which the energies of the components of the signal of the measured pulse wave are determined as the energies of each phase and compared with the corresponding energies of the components of the signal corresponding to the reference pulse wave in the corresponding phases, and it is better when the period of the measured pulse wave is divided into six phases, five of which are in the first half-cycle, and the sixth is in the second half-cycle.

A method for measuring a pulse wave is proposed, according to which an electric signal corresponding to the measured pulse wave is generated using an acoustic sensor, which is pressed against the body surface above a vein or artery, the sensor is pressed against a stable electrical signal, and this adjustment is carried out until the set value is reached at least one of the amplitude-frequency characteristics of the electric signal, adjust the amplitude-frequency characteristic of the electric s Nala until a prescribed electric signal form, amplitude-frequency characteristics of which are treated and displaying processing results on a recorder. What is new is that the adjustment is carried out both in strength and in the place of pressing until a stable electrical signal is obtained, moreover, an electrical signal is considered stable, corresponding to a series of two or more pulse waves, one after the other and each of which has a prescribed shape, and the amplitude and / or frequency characteristics of the electric signal of the adjacent pulse waves of the series correspond to each other within a predetermined tolerance of differences.

To obtain a stable electrical signal, you can pre-set the number of pulse waves of the series following one after another, each of which has a prescribed shape.

It is better when the electrical signal of the prescribed shape corresponding to the pulse wave consists of two equal half-periods of the measured pulse wave, and the first half-period of the measured pulse wave includes a group of five consecutive sinusoidal half-waves, of which the first, third and fifth sinusoidal half-waves are positive half-waves , and the second and fourth sinusoidal half-waves are negative half-waves, and the amplitudes of the first and second sinusoidal half-waves are greater than litudy subsequent sinusoidal half-waves of the pulse wave period measured.

The pressing force can be adjusted according to the testimony of the dynamometer sensor, mechanically connected to the acoustic sensor.

The acoustic sensor can be pressed to the inside of the wrist at the points of Cun, or Guan, or Chi.

Adjustment can be done manually.

A device for processing pulse wave signals is proposed, which can be used to implement the inventive methods, including an amplitude-frequency acoustic pulse wave sensor adapted to be mounted on the body surface above a vein or artery to generate an electrical signal corresponding to the measured pulse wave, an acoustic correction tool a signal sensor for receiving an electrical signal of a prescribed form, a processing module for processing electric signal of the prescribed form and a recorder that records the processed electrical signal of the prescribed form. What is new is that the pulsodiagnostic device comprises an acoustic sensor positioning device according to the force and / or pressure point to obtain a stable electrical signal of the prescribed shape, the positioning device is electrically connected to the processing module, and the recorder is configured to display the processing module information about the achievement of a stable electric signal prescribed forms.

It is better to use a microphone as an acoustic sensor, and use a camera filled with air, which is placed in front of the microphone and open in the direction of the body surface above a vein or artery, as a means of correction.

The positioning device may contain in one housing an acoustic sensor and a dynamometric pressure sensor, electrically connected to the processing module.

The correction means and the processing module can be made with the possibility of obtaining an electric signal of the prescribed form, consisting of two equal half-periods of the measured pulse wave, and the first half-period of the measured pulse wave includes a group of five consecutive sinusoidal half-waves, of which the first, third and fifth sinusoidal half-waves are positive half-waves, and the second and fourth sinusoidal half-waves are negative half-waves, and the amplitudes ervoy and second sinusoidal half-waves is greater than the amplitude of the subsequent half-wave sinusoidal pulse wave period measured.

The processing module can be configured to transmit an electrical signal to the recorder to achieve a stable electrical signal of the prescribed form, which allows the measurement of a pulse wave with a given degree of confidence.

The recorder may be configured to visually display information on achieving a stable electrical signal of a prescribed shape.

A method for processing measurement signals of parameters reflecting the state of organs and / or systems of the body is proposed, according to which, using a measuring sensor or sensors installed on the surface of the body at a specific point or points, signals are measured whose parameters or which reflect components of the internal energy of the body’s channels, the electrical signals generated by the sensor or sensors are presented in the form of a matrix containing comparative sequences of elements used for Application diagnosis by a comparative analysis with a reference sinusoidal sequence elements broken into phases corresponding to the normal state of organs and / or body systems. New is that the generated electrical signals are in the form of at least one matrix, which contains six rows and columns of elements M _ij , the values of which are defined as the deviation between the value of the actual energy of the element or the value of the parameter reflecting the actual energy of the element and the value of the reference energy of the corresponding element or the corresponding value of the parameter reflecting the reference energy of the element, where i is the channel of internal energy, j is the type of internal energy, and the reference syn the soidal sequence of elements is represented as two integer successive half-waves by the sine function, each of which is divided into six equal phases, each of which reflects the reference energy of a certain element or a parameter that reflects the reference energy of a certain element, for the diagnosis, the values and / or balance of deviations are analyzed, which for each channel and / or type of internal energy is defined as the sum of the modules of the values of the rows and / or columns of the matrix, and for all internal energy the total balance is off neny defined as the sum of the balances of deviations for each channel or type of internal energy.

According to the method, in particular, it is possible to measure signals corresponding to a pulse wave, and when converting an electrical signal corresponding to a measured pulse wave, the actual energy of the elements of a particular channel and / or type of internal energy is extracted from such a signal. It is also possible to use the method by measuring the electrical conductivity of the skin at reflex points. The method can also be used when measuring other parameters at reflex points, for example, such as: sensitivity threshold; local temperature; electrical potential; electric capacity; assimilation of carbon dioxide. The values of the elements M _{ij are} best determined as a percentage of the total internal energy of all channels.

The invention is illustrated in graphic materials. Figure 1 presents a block diagram of a “Computer Pulse Analytical System”; figure 2 - its appearance; figure 3 is a sensor unit of this system. Figure 4 presents the shape of an ideal balanced pulse wave corresponding to the normal state of the human body; figure 5 - reference distribution and sequence of individual types of energy of such a pulse wave, called the SIN order.

Figure 5 used the following notation of the elements in accordance with the names used in Chinese medicine: D - element Tree; About - element Fire; 3 - element Earth; M - element Metal; In - element Water; O '- element Fire Minister; the lower indices correspond to: i - the Yin component of Qi energy (even qualities reflecting the potential state); y is the Yan component of Qi energy (odd qualities reflecting the realization state).

6 and 7 are examples of real pulse waves (darker curves) decomposed into even and odd components (lighter curves); on Fig and 9 - State Matrices with complete imbalances and highlighted maximum deviations from the norm, respectively, for the body of a particular patient, compiled by the pulse wave shown in Fig.7.

The invention is illustrated by the example of “Computer pulse analytical system” (hereinafter - PAS).

PAS is designed to obtain an objective assessment of a person’s energy state by the parameters of the pulse waves received by the sensor in the BAT; BAT is usually used on the hands of a person: Tsun, Guan and Chi. The PAS is built on the basis of the description of the basic laws of Eastern philosophy used in eastern medicine: Yin-Yang, W-Sin, Liu Qi (6 Qi), etc. The system implements the fundamental approaches and ideas reflected in these teachings (the law of conservation of energy, the principle smallest action, etc.), and also took into account more than 10 years of research and practical diagnostic experience accumulated by the applicants when using the previous PAS model [prototype US 5381797 C1, 1995].

The PAS in its general form contains (see Figs. 1-3) electrically connected sensor unit 1, processing module 2 and recorder 3. Sensor unit 1 includes a hollow body 4 with a cover 5, which can be displaced relative to each other in the axial direction, stepwise open chamber 6, microphone 7, strain gauge 8, connecting wires 9 and 10. Processing module 2 includes an amplifier 11, analog-to-digital converter 12, waveform analyzer 13. Processing module 2 and its components are made on the basis of a personal computer Tera Pentium, equipped with special software, the principle of operation of which is explained below. The function of the registrar 3 performs the monitor of a personal computer.

PAS works as follows.

Previously, the diagnostician, using the interface (not shown) displayed by the recorder 3, sets the stability indicators of the electrical pulse wave signal: the number of consecutive waves of the series is from 2 to 200; the permissible deviation from each other of the amplitude-frequency characteristics of the adjacent waves of the series is from 0 to 99%. These indicators are recorded in the memory (not shown) of the processing module 2.

To measure the pulse wave, the sensor unit 1 is leaned against the surface of the patient’s body above the vein at the Guan point with the open hole of the chamber 6 (see Fig. 2), while the sensor unit 1 is held by the cover 5. The pressing force from the cover 5 is transmitted to the housing 4 through the load cell 8, the electric signal from which is fed through the wire 10 to the analyzer 13, and when the electric signal reaches a value corresponding to a pressing force of up to 10 N in combination with the stability of the pulse wave electric signal established by the diagnostician, the analy ator 13 reflects on the interface 3 registrar green signal, indicating the reliability of the measurement of the pulse wave.

The pulse wave measurement is as follows.

The acoustic signal of the patient’s pulse wave is converted into an electrical signal by the microphone 7, while the chamber 6 (filled with atmospheric air) corrects the signal, acting as an acoustic transducer. The weak electric signal generated by the microphone 7 is amplified up to 1000 times by the amplifier 11, converted into a digital form by the converter 12 and fed to the analyzer 13 for processing, while both the shape of the measured pulse wave and the results of its processing are reflected on the interface of the recorder 3.

Processing digitized amplified electrical signal of the pulse wave of the patient is carried out by the analyzer 13 as follows.

The memory of the processing module 2 stores information on the reference distribution of the components of the QI energy, called the SIN order (see Fig. 5), corresponding to the reference pulse wave shape (see Fig. 4), determined by the results of many years of research, corresponding to the normal state of the human body . The measured electrical signal of the pulse wave of the prescribed form (darker curves in FIGS. 6 and 7) is decomposed into even and odd components (lighter curves in FIGS. 6 and 7) corresponding to the Yin and Yang components, respectively, of the Qi energy of the measured pulse wave. Based on the data of the even and odd components, the real energy distribution is determined by six elements (real SIN order), and the energies of the five elements are extracted from the five phases of the first half-cycle of the components of the pulse wave, and the energy of the sixth element - from the second half-period. Such a distribution is compared with the distribution according to the reference SIN-order and is entered in the Matrices of the State of Yin and Yang dimension 6x6. The received Status Matrices in the form of tables are reflected on the interface of the registrar 3 and are used for diagnosis (see the example below). Software that allows you to perform these operations is not included in the scope of legal protection in the framework of this application.

The following is an example of clinical data in terms of oriental medicine obtained by examining a patient using PAS.

Patient born in 1950.

Clinical diagnosis in terms of oriental medicine: there is a lesion of the meridians of the liver, gall bladder and large intestine (redundancy).

Complaints: frequent headache, dizziness, and sleep disturbance, sometimes insomnia, there are pains on the inner surface of the lower leg, a feeling of fullness in the stomach, increased irritability, a feeling of lack of strength and weakness, drowsiness during the day, and sweating at night.

PAS examination: the results of the examination are shown in the form of the Matrix of Yin State and the State Matrix of Yang (see Fig. 8 and 9).

The state matrices show disturbances in the energy of all the meridians of the body, while the maximum changes in the energy of meridians are as follows: the liver meridian has a wind excess of 0.8% with a total imbalance of this meridian of 2.22%; the gallbladder meridian has an excess of Wind of 1.48%, the lack of Cold in the gallbladder of 0.8% and the lack of Fire of 0.51% with a total imbalance of this meridian of 3.43%; the large intestine meridian has an excess of Dryness of 1.17% with a total imbalance of this meridian of 2.49%.

Condition matrices provide a more accurate and expanded diagnosis, which also serves as recommendations for treatment.

Thus, the data on the diagnosis of the state of the body obtained using PAS confirm the diagnosis obtained by the methods of oriental medicine, and are also more accurate and informative.

Claims (27)

1. The method of processing pulse wave signals, according to which generate an electrical signal corresponding to the measured pulse wave, using a sensor that is installed on the surface of the body above a vein or artery, adjust the amplitude-frequency characteristic of the generated electrical signal to obtain an electrical signal of the prescribed form in the form of lines from the group of consecutive sinusoidal half-waves of the period of the measured pulse wave, and the amplitudes of the first and second sinusoidal half-waves are greater than the amplitudes of the subsequent sinusoidal half-waves of the period of the measured pulse wave, and carry out a comparative analysis of the amplitude-frequency characteristics of the electrical signal of the prescribed form for diagnosis, characterized in that when adjusting the amplitude-frequency characteristics of the generated electric signal, an electrical signal of the prescribed form is obtained, consisting of two equal in duration half periods of the measured pulse wave, and in the first half period of the measured pulse wave include g UPPU from five consecutive sinusoidal half-waves, of which the first, third and fifth sinusoidal half-waves are positive half-waves, and the second and fourth sinusoidal half-waves are negative half-waves, according to the obtained amplitude-frequency characteristics of the electrical signal of the prescribed form, determine its energy and / or energy of the components of the electrical signal prescribed form and carry out a comparative analysis to make a diagnosis by comparing the energies of the components of the signal by measuring my pulse wave with the reference energies constitute the shape of the pulse wave signal corresponding to the normal state of organs and / or body systems, and / or by comparing measured energy components of the pulse wave signal with each other. 2. The method according to claim 1, characterized in that in the second half-period of the measured pulse wave include a group of consecutive sinusoidal half-waves, the amplitude of each of which is less than the amplitude of any of the first five sinusoidal half-waves of the first half-period of the measured pulse wave. 3. The method according to claim 1, characterized in that the sensor is installed on the inner part of the wrist at points Cun, or Guan, or Chi. 4. The method according to claim 1, characterized in that the electrical signal corresponding to the measured pulse wave is generated using an acoustic sensor, which is installed and pressed over a vein or artery, and adjust the strength and direction of compression to obtain a stable electrical signal. 5. The method according to claim 1, characterized in that the pulse wave is used as a reference pulse wave in the form of a signal in the form of a group of consecutive reference half-waves that vary according to the sine law. 6. The method according to claim 5, characterized in that a pulse wave is used as the reference pulse wave, the signal energy for the period of which is equal to the signal energy of the prescribed shape of the measured pulse wave for the period. 7. The method according to claim 5, characterized in that the group of consecutive reference half-waves is represented as a line of the signal corresponding to it so that the amplitudes of the first and second reference half-waves of the first half-period of the reference pulse wave equal to the half-period of the measured pulse wave are equal to each other and more amplitudes third, fourth and fifth reference half-waves equal to each other, the first, third and fifth reference half-waves being positive half-waves, and the second and fourth reference half-waves being negative luvolnami, and the second half cycle of the reference pulse wave include a group of successive half-waves of damped reference amplitude each of which is smaller than the amplitude of any of the first five half waves of the first half cycle of the reference pulse wave reference. 8. The method according to claim 7, characterized in that the line corresponding to the signal of the reference pulse wave is decomposed into even and odd components in the form of two lines, each of which consists of a group of consecutive half waves, the sum of the ordinates of the lines of even and odd components with the same the abscissa is equal to the ordinate of the signal line of the reference pulse wave with the same abscissa, moreover, in the first half-period, the lines of even and odd components coincide, and their ordinates are less than the corresponding ordinates of the signal line of the reference pulse wave and coincide with them in sign, and in the second half-period, the line of the odd component is obtained by plotting the line opposite in the ordinate and the symmetric line of the odd component of the first half-period relative to the point on the abscissa axis corresponding to the middle of the period, and the line of the odd component passes through this point, and the line the even component of the second half-cycle is obtained by plotting a line symmetrical to the even component of the first half-cycle with respect to the axis parallel to the ordinate and passing through the point in the middle of the period on the x-axis. 9. The method according to claim 1, characterized in that the signal line of the prescribed shape of the measured pulse wave is decomposed into even and odd components in the form of two lines, each of which consists of a group of consecutive half waves, the sum of the ordinates of the lines of even and odd components with the same abscissa equal to the ordinate of the signal line of the prescribed form with the same abscissa, and in the first half-period of the measured pulse wave include groups of five consecutive derivatives of half waves, the amplitudes of the first and second derivatives of the half the waves are larger than the amplitudes of the subsequent half-wave derivatives of the first half-wave of the pulse wave, the first, third and fifth derivatives of half-waves are positive half-waves, and the second and fourth derivatives of half-waves are negative half-waves, in the second half-period the line of the even component is obtained by constructing a line symmetrical with the line of the even component of the first half period with respect to the axis parallel to the ordinate axis and passing through the midpoint of the period on the abscissa axis, and the line of the odd component of the second A half-period is obtained by plotting a line symmetrical to the line of the odd component of the first half-period with respect to a point on the abscissa axis corresponding to the middle of the period, and the line of the odd component passes through this point. 10. The method according to claim 1, characterized in that the period of the measured pulse wave is divided into several phases, the energies of the components of the signal of the measured pulse wave are determined as the energies of each phase, and they are compared with the corresponding energies of the components of the signal corresponding to the reference pulse wave in the corresponding phases. 11. The method according to claim 10, characterized in that the period of the measured pulse wave is divided into six phases, five of which are in the first half-cycle, and the sixth is in the second half-period. 12. A method for measuring a pulse wave, according to which an electrical signal corresponding to the measured pulse wave is generated using an acoustic sensor, which is pressed against the body surface above a vein or artery, regulate the pressure force of the sensor to obtain a stable electrical signal, and such adjustment is carried out until the established the values of at least one of the amplitude-frequency characteristics of the electric signal adjust the amplitude-frequency characteristic of the electric signal to half exercises of an electric signal of a prescribed form, the amplitude-frequency characteristics of which are processed and displayed on the recorder, characterized in that the adjustment is carried out both in strength and in the place of pressing until a stable electric signal is obtained, and the electric signal corresponding to a series of two is considered stable or more pulse waves following one after another and each of which has a prescribed shape, and the amplitude and / or frequency characteristics of the electric signal are adjacent their pulse wave series correspond to each other within a predetermined relative tolerance of differences. 13. The method according to p. 12, characterized in that in order to obtain a stable electric signal, the number of pulse waves of the series following one after another, each of which has a prescribed shape, is pre-set. 14. The method according to p. 12, characterized in that the electrical signal of the prescribed shape, corresponding to the pulse wave, consists of two equal in duration half-periods of the measured pulse wave, and the first half period of the measured pulse wave includes a group of five consecutive sinusoidal half-waves, of which the first , the third and fifth sinusoidal half-waves are positive half-waves, and the second and fourth sinusoidal half-waves are negative half-waves, and the amplitudes of the first and second sinusoidal x half-waves are greater than the amplitudes of the subsequent sinusoidal half-waves of the period of the measured pulse wave. 15. The method according to p. 12, characterized in that the pressing force is adjusted according to the testimony of the dynamometric sensor, mechanically connected to the acoustic sensor. 16. The method according to p. 12, characterized in that the acoustic sensor is pressed against the inside of the wrist at points Cun, or Guan, or Chi. 17. The method according to p. 12, characterized in that the adjustment is carried out manually. 18. A device for processing pulse wave signals, including an amplitude-frequency acoustic pulse wave sensor, adapted to be installed on the body surface above a vein or artery to generate an electrical signal corresponding to the measured pulse wave, means for adjusting the signal generated by the acoustic sensor to obtain an electrical signal of the prescribed form a processing module for processing an electrical signal of a prescribed form and a registrar registering the processed ele a tertiary signal of a prescribed shape, characterized in that it contains a positioning device for the acoustic sensor by force and / or pressure point to obtain a stable electrical signal of a prescribed shape, the positioning device is electrically connected to the processing module, and the recorder is configured to display information of the processing module about achieving a stable electrical signal of the prescribed form. 19. The device according to p. 18, characterized in that a microphone is used as an acoustic sensor, and a camera filled with air is used as a means of correction, which is placed in front of the microphone and open in the direction of the body surface above a vein or artery. 20. The device according to p. 18, characterized in that the positioning device contains in one housing an acoustic sensor and a load cell force sensor, electrically connected to the processing module. 21. The device according to p. 18, characterized in that the correction tool and the processing module are configured to receive an electrical signal of the prescribed form, consisting of two equal in duration half-periods of the measured pulse wave, and in the first half-period of the measured pulse wave includes a group of five consecutive sinusoidal half-waves, of which the first, third and fifth sinusoidal half-waves are positive half-waves, and the second and fourth sinusoidal half-waves are negative half-waves, and the amplitudes of the first and second sinusoidal half-waves are greater than the amplitudes of the subsequent sinusoidal half-waves of the period of the measured pulse wave. 22. The device according to p. 18, characterized in that the processing module is configured to transmit to the recorder an electrical signal to achieve a stable electrical signal of the prescribed form, allowing the measurement of a pulse wave with a given degree of confidence. 23. The device according to p. 18, characterized in that the recorder is configured to visually display information about achieving a stable electrical signal of the prescribed form. 24. A method of processing signals for measuring parameters reflecting the state of organs and / or systems of the body, according to which, using a measuring sensor or sensors installed on the surface of the body at a specific point or points, signals are measured whose parameters or which reflect components of the internal energy of the body’s channels the electrical signals generated by the sensor or sensors are presented in the form of a matrix containing comparative sequences of elements used for diagnosis and by comparative analysis with a reference sinusoidal sequence elements broken into phases corresponding to the normal state of organs and / or systems of the body, characterized in that the generated electrical signals are in the form of at least one matrix consisting of six rows and columns of elements M _ij, the values of which are defined as the deviation between the value of the actual energy of the element or the value of the parameter reflecting the actual energy of the element and the value of the reference energy, respectively of the element or the corresponding value of the parameter reflecting the reference energy of the element, where i is the channel of internal energy, j is the type of internal energy, and the reference sinusoidal sequence of elements is represented as two integer successive half-waves by the sine function, each of which is divided into six equal phases, each of which reflects the reference energy of a particular element or a parameter that reflects the reference energy of a certain element, the values and / or deviation balance are analyzed for diagnosis which, for each channel and / or type of internal energy, is defined as the sum of the modules of the values of the rows and / or columns of the matrix, and for all internal energy, the total balance of deviations is defined as the sum of all balance deviations for each channel or type of internal energy. 25. The method according to p. 24, characterized in that they measure the signals corresponding to the pulse wave, and when converting the electrical signal corresponding to the measured pulse wave, the actual energy of the elements of a certain channel and / or type of internal energy is extracted from such a signal. 26. The method according to paragraph 24, wherein the measurement of the electrical conductivity of the skin at the reflex points. 27. The method according to paragraph 24, wherein the values of the elements M _{ij are} determined as a percentage of the total internal energy of all channels.

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