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RU2298416C2 - Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi - Google Patents

Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi Download PDF

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Publication number
RU2298416C2
RU2298416C2 RU2004105031/15A RU2004105031A RU2298416C2 RU 2298416 C2 RU2298416 C2 RU 2298416C2 RU 2004105031/15 A RU2004105031/15 A RU 2004105031/15A RU 2004105031 A RU2004105031 A RU 2004105031A RU 2298416 C2 RU2298416 C2 RU 2298416C2
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RU
Russia
Prior art keywords
factor
factor vii
vii
polypeptide
related polypeptide
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RU2004105031/15A
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English (en)
Russian (ru)
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RU2004105031A (ru
Inventor
Расмус РЕЙКЕР (DK)
Расмус РЕЙКЕР
Original Assignee
Ново Нордиск Хелт Кэр Аг
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Application filed by Ново Нордиск Хелт Кэр Аг filed Critical Ново Нордиск Хелт Кэр Аг
Publication of RU2004105031A publication Critical patent/RU2004105031A/ru
Application granted granted Critical
Publication of RU2298416C2 publication Critical patent/RU2298416C2/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2004105031/15A 2001-07-20 2002-07-19 Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi RU2298416C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101127 2001-07-20
DKPA200101127 2001-07-20

Publications (2)

Publication Number Publication Date
RU2004105031A RU2004105031A (ru) 2005-04-20
RU2298416C2 true RU2298416C2 (ru) 2007-05-10

Family

ID=8160632

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004105031/15A RU2298416C2 (ru) 2001-07-20 2002-07-19 Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi

Country Status (16)

Country Link
EP (1) EP1411973A1 (fr)
JP (1) JP2004534855A (fr)
KR (1) KR20040015821A (fr)
CN (1) CN1304050C (fr)
AU (1) AU2002354846B2 (fr)
BR (1) BR0211256A (fr)
CA (1) CA2452677A1 (fr)
CZ (1) CZ200439A3 (fr)
HU (1) HUP0400976A3 (fr)
IL (1) IL159622A0 (fr)
MX (1) MXPA04000415A (fr)
NO (1) NO20040235L (fr)
PL (1) PL369077A1 (fr)
RU (1) RU2298416C2 (fr)
WO (1) WO2003007983A1 (fr)
ZA (1) ZA200400012B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9433664B2 (en) 2010-10-06 2016-09-06 Medimmune Limited Factor II and fibrinogen for treatment of haemostatic disorders
RU2800719C2 (ru) * 2017-02-10 2023-07-26 Шанхай Бенемае Фармасьютикалз Корпорэйшн Антитела к фактору xi
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001005353A2 (fr) 1999-07-14 2001-01-25 Novo Nordisk A/S UTILISATION DE FVIIa OU D'UN ANTAGONISTE DE FACTEUR TISSULAIRE TF POUR REGULER L'EXPRESSION GENIQUE, ET MIGRATION CELLULAIRE OU CHIMIOTAXIE
CN1863908B (zh) 2003-09-09 2010-08-04 诺和诺德医疗保健公司 凝固因子ⅶ多肽
RU2006115783A (ru) * 2003-11-20 2007-12-27 Ново Нордиск Хелс Кеа Аг (Ch) Терапевтическое применение фактора xi
JP2007520530A (ja) * 2004-02-05 2007-07-26 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 外傷の遅発型合併症の治療のための、VIIa因子又はVIIa因子等価物の使用
WO2006128497A1 (fr) * 2005-06-01 2006-12-07 Novo Nordisk A/S Formule pharmaceutique de facteur xi
BRPI0922344A2 (pt) 2008-12-19 2017-10-24 3B Pharmaceuticals Gmbh inibidores de tfpi e métodos de uso
WO2011115712A2 (fr) 2010-03-19 2011-09-22 Baxter International Inc Inhibiteurs de tfpi et procédés d'utilisation associés
CN104302306B (zh) 2012-03-21 2019-03-22 百深有限责任公司 Tfpi抑制剂及其使用方法
KR20160111520A (ko) * 2014-01-31 2016-09-26 다나-파버 캔서 인스티튜트 인크. 디히드로프테리디논 유도체 및 그의 용도
CA2986441A1 (fr) 2015-06-12 2016-12-15 Dana-Farber Cancer Institute, Inc. Therapie d'association utilisant des inhibiteurs de transcription et des inhibiteurs de kinases
US10913752B2 (en) 2015-11-25 2021-02-09 Dana-Farber Cancer Institute, Inc. Bivalent bromodomain inhibitors and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252217A (en) * 1991-05-07 1993-10-12 Association Pour L'essor De La Transfusion Sanguine Dans La Region Du Nord Blood coagulation factor XI concentrate having high specific activity, suitable for therapeutic use, and process for preparing same
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
RU2214833C2 (ru) * 1994-10-24 2003-10-27 Ново Нордиск Хелс Кеар Аг Модифицированный фактор vii

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116213A (ja) * 1982-12-24 1984-07-05 Unitika Ltd エアゾ−ル組成物
AU593042B2 (en) * 1985-11-26 1990-02-01 Novo Nordisk Health Care Ag Compositions and methods for the treatment of bleeding disorders
EP1319067A2 (fr) * 2000-09-13 2003-06-18 Novo Nordisk A/S Variants du facteur vii de coagulation humaine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
US5252217A (en) * 1991-05-07 1993-10-12 Association Pour L'essor De La Transfusion Sanguine Dans La Region Du Nord Blood coagulation factor XI concentrate having high specific activity, suitable for therapeutic use, and process for preparing same
RU2214833C2 (ru) * 1994-10-24 2003-10-27 Ново Нордиск Хелс Кеар Аг Модифицированный фактор vii

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TORBET J.The trombin activation pathway modulates the assembly, structure and lysis of human plasma clots in vitro/. Thromb.Haemost., 1995, May, v.73(5), p.785-792. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9433664B2 (en) 2010-10-06 2016-09-06 Medimmune Limited Factor II and fibrinogen for treatment of haemostatic disorders
RU2606155C2 (ru) * 2010-10-06 2017-01-10 Медиммьюн Лимитед Фактор ii и фибриноген для лечения гемостатических нарушений
RU2800719C2 (ru) * 2017-02-10 2023-07-26 Шанхай Бенемае Фармасьютикалз Корпорэйшн Антитела к фактору xi
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Also Published As

Publication number Publication date
PL369077A1 (en) 2005-04-18
RU2004105031A (ru) 2005-04-20
BR0211256A (pt) 2004-07-27
MXPA04000415A (es) 2004-11-22
KR20040015821A (ko) 2004-02-19
IL159622A0 (en) 2004-06-01
HUP0400976A3 (en) 2006-01-30
CN1556710A (zh) 2004-12-22
EP1411973A1 (fr) 2004-04-28
CN1304050C (zh) 2007-03-14
JP2004534855A (ja) 2004-11-18
HUP0400976A2 (hu) 2004-08-30
CZ200439A3 (cs) 2005-03-16
NO20040235L (no) 2004-03-17
CA2452677A1 (fr) 2003-01-30
WO2003007983A1 (fr) 2003-01-30
AU2002354846B2 (en) 2007-08-02
ZA200400012B (en) 2004-08-17

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20080720