RU2270028C2 - Method for revaccination against epidemic parotitis in children in far north - Google Patents

Abstract

FIELD: medicine, pediatrics.

SUBSTANCE: children who are not 6 yr old since April to July should be revaccinated with alive parotitis vaccine next year only, during the same period - since April to July. The innovation provides development of tense immunity in 6-yr-old children.

EFFECT: higher efficiency of revaccination.

12 ex

Description

The invention relates to medicine, more specifically to pediatrics. It can be used to revaccinate mumps in the Far North.

A known method of mass revaccination of mumps by introducing a lively mumps vaccine (ZHPV) at the age of 6 years [New calendar of vaccinations. - Order of the Ministry of Health of the Russian Federation No. 229 dated 06/20/2001].

The known method does not take into account the peculiarities of adaptation of the child’s immune system to the ongoing changes in climatic indicators in the Far North - “polar night” and “polar day”, short seasons of northern spring, summer and autumn and long cold winters. This reduces the effectiveness of vaccinations and, accordingly, increases the likelihood of mumps. Revaccination according to the known method throughout the year in the Far North provides significant material and labor costs for the work of medical teams and helicopter transport.

The objective of the invention is to increase the efficiency of revaccination of mumps and reduce material and labor costs.

The problem is solved due to the fact that in the method of revaccination of children living in the Far North, which consists in the introduction of a lively mumps vaccine after reaching the age of 6, according to the invention, a group of children to be revaccinated is formed and the vaccine is administered from April to July.

The period from April to July is the most favorable for the formation of a stable post-vaccination immunity, which contributes to the effectiveness of revaccination.

The method is as follows. Children living in the Far North and reaching 6 years of age are united in a booster group, invited to special rooms. Each of them is given a live mumps vaccine only from April to July. Children who are under 6 years old from March to July are vaccinated against mumps the following year, and only from April to July.

Example 1. Konovalova M., 6 years old. Included in the group of people to be vaccinated against mumps. Revaccinated with HPV in January. One year after revaccination, anti-mumps antibodies were detected at a titer of <1:10 (seronegative).

Example 2. Lomakin P., 6 years 11 months. Revaccinated with HPV in February. One year after revaccination, anti-mumps antibodies were detected at a titer <1:10 (seronegative).

Example 3. Tareeva I., 6 years 6 months. Revaccinated with HPV in March. One year after revaccination, anti-mumps antibodies were detected at a titer of <1:10 (seronegative).

Example 4. Ivanova S., 6 years 6 months. Revaccinated with HPV in April. One year after revaccination, anti-mumps antibodies were detected at a titer of 1: 160.

Example 5. Menshikova O., 6 years 6 months. Revaccinated with HPV in May. One year after revaccination, antipartite antibodies were detected at a titer of 1: 640.

Example 6. Tarasova N., 6 years 6 months. Revaccinated with HPV in June. One year after revaccination, anti-mumps antibodies were detected at a titer of 1: 320.

Example 7. Kochkina L., 6 years 6 months. Revaccinated with HPV in July. One year after revaccination, anti-mumps antibodies were detected at a titer of 1: 160.

Example 8. Tikhonov O., 6 years 10 months. Revaccinated with HPV in August. One year after revaccination, anti-mumps antibodies were detected at a titer of <1:10 (seronegative).

Example 9. Korkin I., 6 years 11 months. Revaccinated with HPV in September. One year after revaccination, anti-mumps antibodies were detected at a titer of <1:10 (seronegative).

Example 10. Razumov P., 6 years 10 months. Revaccinated with HPV in October. One year after revaccination, anti-mumps antibodies were detected at a titer of <1:10 (seronegative).

Example 11. Konstantinov A., 6 years 9 months. Revaccinated with HPV in November. One year after revaccination, anti-mumps antibodies were detected at a titer of <1:10 (seronegative).

Example 12. Rudneva V., 6 years 6 months. Revaccinated with HPV in December. One year after revaccination, anti-mumps antibodies were detected at a titer of <1:10 (seronegative).

Using the proposed method has the following advantages.

The effectiveness of revaccination of children living in the Far North is increasing. In addition, the vaccination period is reduced by 3 times, which leads to a reduction in material and labor costs.

In total, in the conditions of the Far North, 621 people were vaccinated with HPV according to the proposed method. An immunological examination conducted a year later showed that the highest rates of anti-mumps immunity were found in children revaccinated with a lively mumps vaccine from April to July.

Claims (1)

The way to revaccinate children against mumps in the Far North, which consists in the introduction of a lively mumps vaccine, characterized in that children who are under the age of 6 from April to July are revaccinated only next year in the same period - from April to July.