RU216918U1 - AEROSOL DISPENSER FOR GROUP INHALATION - Google Patents

Abstract

The utility model relates to aerosol technology and can be used in medical practice for group inhalation (aerosol) vaccination in a complicated epidemiological situation and aerosol therapy for group inhalations. The aerosol nebulizer for group inhalation contains an ejection-type nebulization device with a container for the nebulized liquid, placed on a stand. The spray device is made in the form of a spray head containing diametrically located fine nozzles with nozzles directed at an angle to the horizontal plane. With a productivity of at least 60 ml/min of the sprayed liquid, the average median size of the sprayed particles is not more than 5 microns, while compressed air is supplied to the spray device at a flow rate of at least 60 l/min at an operating pressure of at least 2 atm (0.203 MPa). The aerosol dispenser ensures the creation of a homogeneous aerosol cloud with a given aerosol concentration in rooms for group inhalation up to 150 m ³ in a short time (no more than 1/5 of the inhalation session time). 1 tab., 4 ill.

Description

The utility model relates to aerosol technology and can be used in medical practice for group inhalation (aerosol) vaccination in a complicated epidemiological situation, when it is necessary to vaccinate large contingents of people in the shortest possible time, and aerosol therapy for group inhalation. An aerosol dispenser is proposed, which makes it possible to create a homogeneous aerosol cloud in a room with a given concentration of the sprayed medical preparation.

There are various aerosol generators designed for group inhalation. For the treatment and prevention of respiratory diseases by saturating the room air with electric aerosols of aqueous solutions of medicinal substances, there is a generator of electric aerosols group GEG-2 (Russia). The generator ensures the creation of a "working" concentration of aerosol in the room for group inhalation up to 30 m ³ .

The ultrasonic halogenerator (chamber inhaler) Albedo IN8 (Russia) is equipped with a generator and a high-performance fan to create a salt aerosol cloud in a room up to 50 m ³ in volume. Complete with a long corrugated hose that allows you to install the generator in a clean room outside the inhalation chamber. Dispenser capacity - 500 ml. The duration of continuous operation from one refueling is about 1.5 hours. It can be used in halochambers, phyto- and aromatherapy rooms, sea (salt fog) chambers, in microclimate maintenance systems, in cases where it is necessary to fill a closed volume with an aerosol.

For specific passive prevention of viral infections in broilers, a VAG-2 vortex aerosol generator is used [1]. The generator with the help of an additional fan ensures uniform distribution of aerosol in a room up to 50 m ³ .

The general disadvantages of these devices include the need for additional technical means to ensure uniform distribution of aerosol in the volume of the room (fans, etc.) and the possibility of creating a “working” concentration of aerosol in rooms up to 50 m ³ only, however, immunization with the plague vaccine by inhalation are carried out in stationary or temporary type premises with a volume of up to 150 m ³ (height from 2.8 to 4 m) [2], therefore, these generators cannot provide the necessary concentration of vaccine aerosol.

For the practical implementation of the method of group aerosol vaccination and aerosol therapy, a pneumatic sprayer is used to create a cloud of aerosol of liquid preparations that expands radially in the horizontal direction [3]. On a vertical stand, with the help of holders with rods, there are installed: at the bottom - a straight-jet ejection-type atomizer, the gas-liquid nozzle of which is directed vertically, at the top - a radial-slot type pneumatic device, the radial slot of which is oriented horizontally, while the radial-slot type device is located exactly above the atomizer; compressed air at a pressure of 0.9-1.4 atm (0.10-0.15 MPa) is simultaneously fed through the line to a straight-jet ejection type sprayer and a radial-slot type pneumatic device. By varying the vertical distance between a straight-jet ejection type sprayer and a radial-slot type pneumatic device, it seems possible to create an aerosol cloud of the required configuration at a given height, including in the aspiration zone. "Guidelines for the vaccination of especially dangerous infections" [2] recommends the described device for aerosol immunization. It is the closest device to the claimed utility model.

The disadvantages of the described device are:

- low productivity of the nebulizer (4-5 ml / min) at an operating pressure of compressed air of 0.9-1.4 atm (0.10-0.15 MPa), which greatly increases the time to reach the "working" concentration of the sprayed medicinal aerosol means in the room for inhalation;

- to ensure the uniform distribution of the aerosol concentration in the volume of the room, it is necessary to have an additional technical means - a pneumatic device of a radial-slot type.

The objective of the claimed utility model is to ensure the creation of a homogeneous aerosol cloud with a given aerosol concentration in rooms for group inhalation with a volume of up to 150 m ³ in a short time (no more than 1/5 of the inhalation session time).

The technical result is achieved by the fact that in the claimed sprayer, which is an ejection-type spraying device with a container for the sprayed liquid, located on a telescopic rack at a distance above the floor level, depending on the height of the ceiling of the room, the spraying device is made in the form of a spraying head containing several diametrically located finely dispersed nozzles with nozzles directed at an angle to the horizontal plane, ensuring the uniformity of the concentration of the aerosol cloud in the room. The presence of several nozzles increases the productivity of the sprayer and allows you to achieve a given concentration of aerosol in the volume of the room in a short time. The flow rate of compressed air supplied to the spray device is at least 60 l/min at an operating pressure of at least 2 atm (0.203 MPa). The performance of the spray head with four fine nozzles is at least 60 ml/min. The average median size of sprayed aerosol particles does not exceed 5 μm.

A group inhalation aerosol dispenser is shown in FIG. 1-4.

In FIG. 1 is a schematic representation of a group inhalation aerosol dispenser coupled to a compressor.

In FIG. 2 the photo shows a general view of the aerosol dispenser for group inhalation.

In FIG. 3 shows a spray head with four nozzles.

The aerosol generator in a specific design, shown in Fig. 1-4, contains a compressor unit 1 and an aerosol dispenser containing a telescopic rack 2 with a spray head located on it with four fine nozzles 3 (Fig. 1 and 2). The spray head is located on a telescopic stand. Diametrically opposite nozzles are located at an angle of 90° relative to each other (Fig. 3). Nozzles of nozzles are directed at an angle of 45° to the horizontal plane. A container for sprayed liquid 4 is connected to the spray head by means of a hose.

The output of the spray head with four fine nozzles is 60 ml/min. The average median size of sprayed aerosol particles does not exceed 5 µm.

The operation of the aerosol sprayer is as follows: compressed air with a flow rate of 60 l / min at a pressure of 2.0-2.2 atm (0.203-0.223 MPa) is supplied to the spray head. By injection, the medicinal product enters the spray head from the container associated with it and is sprayed.

The tests of the developed utility model (using biologically active liquid preparations with different viscosities) showed that the claimed device provides a uniform distribution of the mass concentration of the drug aerosol in the volume of the room for group inhalation, and also ensures that the specified aerosol concentration is achieved in a short time (no more than 1 /5 from the time of the inhalation session). The aerosol dispenser provides the creation of the aerosol parameters necessary for group inhalation (table).

Table. Utility Model Test Results

The main parameters of the drug aerosol for group inhalation Required Parameter Test results Mass-average diameter of aerosol particles - d _50, microns 3 to 5 3.0 to 5.0 Median distribution of particle diameters, σ _g, µm 1.5 to 4.0 from 2.06 to 2.7 The content of aerosol particles with a diameter of up to 10.0 microns (by mass),%, not less than 85 from 86 to 97 Mass concentration of aerosol in rooms with a volume of 30 to 150 m ³ , mg / m ³ from 200 to 700 from 150 to 890 Accuracy of maintaining a given level of aerosol mass concentration in the room during the session, % ±10 ±9.0

List of sources used

1. A device for obtaining highly dispersed aerosols. - Patent for invention RU 2617396 C2, publ. 04/24/2017.

2. Guidelines for the vaccination of especially dangerous infections / Ed. prof. I.V. Borisevich, prof. I.V. Darmov. - Kirov: LLC "Kirov Regional Printing House", 2011 - 152 p.

3. Pneumatic atomizer for creating a radially expanding horizontally expanding aerosol cloud of mechanically sensitive liquids. - Utility model patent RU 81646 U1, publ. 03/27/2009.

Claims (1)

An aerosol nebulizer for group inhalation, containing an ejection-type nebulization device with a container for the nebulized liquid, placed on a stand, characterized in that the nebulization device is made in the form of a nebulizing head containing diametrically located fine nozzles with nozzles directed at an angle to the horizontal plane, with a capacity of at least 60 ml/min of the sprayed liquid provides an average median size of the sprayed particles of not more than 5 microns, while compressed air is supplied to the spraying device with a flow rate of at least 60 l/min at an operating pressure of at least 2 atm (0.203 MPa).

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