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RU2023127634A - Pharmaceutical composition based on a binuclear anionic nitrosyl complex and its use in tablet form for the treatment of cardiovascular and oncological diseases - Google Patents

Pharmaceutical composition based on a binuclear anionic nitrosyl complex and its use in tablet form for the treatment of cardiovascular and oncological diseases Download PDF

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Publication number
RU2023127634A
RU2023127634A RU2023127634A RU2023127634A RU2023127634A RU 2023127634 A RU2023127634 A RU 2023127634A RU 2023127634 A RU2023127634 A RU 2023127634A RU 2023127634 A RU2023127634 A RU 2023127634A RU 2023127634 A RU2023127634 A RU 2023127634A
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RU
Russia
Prior art keywords
pharmaceutical composition
item
cardiovascular
composition according
treatment
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RU2023127634A
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Russian (ru)
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RU2843160C2 (en
Inventor
Вероника Олеговна Новикова
Олеся Викторовна Покидова
Наталия Алексеевна Санина
Original Assignee
Федеральное Государственное Бюджетное Учреждение Науки Федеральный Исследовательский Центр Проблем Химической Физики И Медицинской Химии Российской Академии Наук (Фиц Пхф И Мх Ран)
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Publication of RU2023127634A publication Critical patent/RU2023127634A/en
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Claims (6)

1. Фармацевтическая композиция, содержащая класс NO-доноров, спонтанно генерирующих NO в отсутствии дополнительной термо-, фото- и ферментативной активации, и стабилизатор, в том числе пептидной природы, при соотношении ингредиентов, мас.%: NO-донор - 0,2-0,4, стабилизатор и/или индифферентный наполнитель - 99,6-99,8.1. A pharmaceutical composition containing a class of NO donors that spontaneously generate NO in the absence of additional thermal, photo and enzymatic activation, and a stabilizer, including one of peptide nature, with the ratio of ingredients, wt.%: NO donor - 0.2-0.4, stabilizer and/or indifferent filler - 99.6-99.8. 2. Твердая дозированная лекарственная форма, преимущественно для перорального применения в виде таблетки, включающая фармацевтическую композицию по п. 1, а также вспомогательные вещества при следующем содержании компонентов, мас.%:2. A solid dosage form, primarily for oral use in the form of a tablet, comprising a pharmaceutical composition according to item 1, as well as excipients with the following component content, wt.%: фармацевтическая композиция по п. 1 - 0,2-0,4, поливинилпирролидон - 5 и лактоза - остальное; илиa pharmaceutical composition according to item 1 - 0.2-0.4, polyvinylpyrrolidone - 5 and lactose - the rest; or фармацевтическая композиция по п. 1 - 0,2-0,4, стабилизатор, в том числе пептидной природы - 50 и лактоза - остальное; илиa pharmaceutical composition according to item 1 - 0.2-0.4, a stabilizer, including one of peptide nature - 50 and lactose - the rest; or фармацевтическая композиция по п. 1 - 0,2-0,4, стабилизатор, в том числе пептидной природы - остальное.pharmaceutical composition according to item 1 - 0.2-0.4, stabilizer, including of peptide nature - the rest. 3. Применение фармацевтической композиции по п. 1 в твердой таблетированной форме для лечения сердечно-сосудистых и онкологических заболеваний.3. Use of the pharmaceutical composition according to item 1 in solid tablet form for the treatment of cardiovascular and oncological diseases.
RU2023127634A 2023-10-27 Pharmaceutical composition based on a binuclear anionic nitrosyl complex and its use in a tabletted form for the treatment of cardiovascular diseases and oncological diseases RU2843160C2 (en)

Publications (2)

Publication Number Publication Date
RU2023127634A true RU2023127634A (en) 2025-04-28
RU2843160C2 RU2843160C2 (en) 2025-07-07

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