[go: up one dir, main page]

RU2017103751A3 - - Google Patents

Download PDF

Info

Publication number
RU2017103751A3
RU2017103751A3 RU2017103751A RU2017103751A RU2017103751A3 RU 2017103751 A3 RU2017103751 A3 RU 2017103751A3 RU 2017103751 A RU2017103751 A RU 2017103751A RU 2017103751 A RU2017103751 A RU 2017103751A RU 2017103751 A3 RU2017103751 A3 RU 2017103751A3
Authority
RU
Russia
Application number
RU2017103751A
Other versions
RU2017103751A (ru
RU2694063C2 (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2017103751A publication Critical patent/RU2017103751A/ru
Publication of RU2017103751A3 publication Critical patent/RU2017103751A3/ru
Application granted granted Critical
Publication of RU2694063C2 publication Critical patent/RU2694063C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
RU2017103751A 2014-07-08 2015-07-08 Тонкодисперсный инсулин, тонкодисперсные аналоги инсулина и способы их промышленного получения RU2694063C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462022026P 2014-07-08 2014-07-08
US62/022,026 2014-07-08
PCT/US2015/039625 WO2016007682A1 (en) 2014-07-08 2015-07-08 Micronized insulin, micronized insulin analogues, and methods of manufacturing the same

Publications (3)

Publication Number Publication Date
RU2017103751A RU2017103751A (ru) 2018-08-08
RU2017103751A3 true RU2017103751A3 (ru) 2018-08-08
RU2694063C2 RU2694063C2 (ru) 2019-07-09

Family

ID=53783921

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017103751A RU2694063C2 (ru) 2014-07-08 2015-07-08 Тонкодисперсный инсулин, тонкодисперсные аналоги инсулина и способы их промышленного получения

Country Status (10)

Country Link
US (1) US10258573B2 (ru)
EP (1) EP3166595B1 (ru)
JP (1) JP6530480B2 (ru)
CN (1) CN106794156B (ru)
BR (1) BR112017000175B1 (ru)
CA (1) CA2954287C (ru)
DK (1) DK3166595T3 (ru)
MX (1) MX375021B (ru)
RU (1) RU2694063C2 (ru)
WO (1) WO2016007682A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6530480B2 (ja) 2014-07-08 2019-06-12 アムファスター ファーマシューティカルズ,インコーポレイティド 微小インスリン、微小インスリン類似体及びそれらの製造方法
US10322168B2 (en) * 2016-01-07 2019-06-18 Amphastar Pharmaceuticals, Inc. High-purity inhalable particles of insulin and insulin analogues, and high-efficiency methods of manufacturing the same
US20210290733A1 (en) * 2018-07-16 2021-09-23 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Injectable micronized human insulin

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
ATE264096T1 (de) * 1994-03-07 2004-04-15 Nektar Therapeutics Verfahren und mittel zur verabreichung von insulin über die lunge
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
US5597893A (en) * 1994-10-31 1997-01-28 Eli Lilly And Company Preparation of stable insulin analog crystals
YU18596A (sh) * 1995-03-31 1998-07-10 Eli Lilly And Company Analogne formulacije monomernog insulina
SE9501384D0 (sv) * 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
US5985309A (en) 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6310038B1 (en) 1997-03-20 2001-10-30 Novo Nordisk A/S Pulmonary insulin crystals
RU2198181C2 (ru) * 1997-03-20 2003-02-10 Ново Нордиск А/С Не содержащие цинк кристаллы инсулина для применения в легочных композициях
DK1808438T3 (da) 1999-06-29 2014-10-27 Mannkind Corp Rensning og stabilisering af peptid og proteiner i lægemidler
WO2001000674A1 (en) 1999-06-29 2001-01-04 Eli Lilly And Company Insulin crystals for pulmonary administration
AU2001266392A1 (en) 2000-06-27 2002-01-08 Mi Tech Company Limited The controlled release preparation of insulin and its method
WO2002043580A2 (en) 2000-10-27 2002-06-06 Epic Therapeutics, Inc. Production of microspheres
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
DE10235168A1 (de) * 2002-08-01 2004-02-12 Aventis Pharma Deutschland Gmbh Verfahren zur Reinigung von Preproinsulin
GB0300427D0 (en) * 2003-01-09 2003-02-05 Univ Strathclyde Pharmaceutical composition
KR101137785B1 (ko) 2003-07-18 2012-04-25 백스터 인터내셔널 인코포레이티드 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물
WO2005032511A2 (en) 2003-09-30 2005-04-14 Spherics, Inc. Nanoparticulate therapeutic biologically active agents
JP4792457B2 (ja) 2004-03-26 2011-10-12 ユニヴァーシタ’デグリ ステュディ ディ パルマ 高度に呼吸に適したインスリンのマイクロ粒子
EP2036572A1 (en) * 2007-09-04 2009-03-18 Novo Nordisk A/S Process for drying a protein, a protein particle and a pharmaceutical composition comprising the protein particle
WO2013115965A1 (en) 2012-01-31 2013-08-08 Cerulean Pharma Inc. Polymer-agent conjugates, particles, compositions, and related methods of use
JP6530480B2 (ja) 2014-07-08 2019-06-12 アムファスター ファーマシューティカルズ,インコーポレイティド 微小インスリン、微小インスリン類似体及びそれらの製造方法

Also Published As

Publication number Publication date
RU2017103751A (ru) 2018-08-08
CA2954287C (en) 2020-12-22
EP3166595A1 (en) 2017-05-17
WO2016007682A1 (en) 2016-01-14
US20160008287A1 (en) 2016-01-14
MX375021B (es) 2025-03-06
BR112017000175B1 (pt) 2023-11-21
JP2017520593A (ja) 2017-07-27
US10258573B2 (en) 2019-04-16
RU2694063C2 (ru) 2019-07-09
EP3166595B1 (en) 2019-05-15
BR112017000175A2 (pt) 2017-10-31
JP6530480B2 (ja) 2019-06-12
DK3166595T3 (da) 2019-08-05
CN106794156A (zh) 2017-05-31
MX2017000027A (es) 2017-05-01
CN106794156B (zh) 2021-03-09
CA2954287A1 (en) 2016-01-14

Similar Documents

Publication Publication Date Title
BR112016017520A2 (ru)
BR112016016951A2 (ru)
BR112016016756A2 (ru)
BR112016016978A2 (ru)
BR112016018948A2 (ru)
BR112016018327A2 (ru)
BR112016015605A2 (ru)
BR112016018868A2 (ru)
BR112016018384A2 (ru)
BR112016018278A2 (ru)
BR112016018582A2 (ru)
BR112016018556A2 (ru)
BR112016015385A2 (ru)
BR112016018865A2 (ru)
BR112016017262A2 (ru)
BR112016008129A2 (ru)
BR112016016933A2 (ru)
BR112016014460A2 (ru)
BR112016017713A2 (ru)
BR112016018944A2 (ru)
BR112016015645A2 (ru)
BR112016000228A2 (ru)
BR112016016534A2 (ru)
BR112016018043A2 (ru)
BR112016016601A2 (ru)