RU2015155874A - Смежные перекрывающиеся пептиды для лечения аллергии, вызванной клещами домашней пыли - Google Patents
Смежные перекрывающиеся пептиды для лечения аллергии, вызванной клещами домашней пыли Download PDFInfo
- Publication number
- RU2015155874A RU2015155874A RU2015155874A RU2015155874A RU2015155874A RU 2015155874 A RU2015155874 A RU 2015155874A RU 2015155874 A RU2015155874 A RU 2015155874A RU 2015155874 A RU2015155874 A RU 2015155874A RU 2015155874 A RU2015155874 A RU 2015155874A
- Authority
- RU
- Russia
- Prior art keywords
- sequence
- subjects
- reactivity
- house dust
- seq
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title claims 198
- 102000004196 processed proteins & peptides Human genes 0.000 title claims 125
- 206010020751 Hypersensitivity Diseases 0.000 title claims 31
- 230000007815 allergy Effects 0.000 title claims 31
- 208000026935 allergic disease Diseases 0.000 title claims 20
- 150000001413 amino acids Chemical class 0.000 claims 122
- 241000238711 Pyroglyphidae Species 0.000 claims 98
- 229940046533 house dust mites Drugs 0.000 claims 98
- 230000009257 reactivity Effects 0.000 claims 96
- 230000000172 allergic effect Effects 0.000 claims 68
- 208000010668 atopic eczema Diseases 0.000 claims 68
- 229920001184 polypeptide Polymers 0.000 claims 63
- 210000001744 T-lymphocyte Anatomy 0.000 claims 48
- 125000000539 amino acid group Chemical group 0.000 claims 28
- 239000000203 mixture Substances 0.000 claims 10
- 102000007079 Peptide Fragments Human genes 0.000 claims 7
- 108010033276 Peptide Fragments Proteins 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 108010061608 Dermatophagoides pteronyssinus antigen p 2 Proteins 0.000 claims 5
- 239000013566 allergen Substances 0.000 claims 5
- 229960004784 allergens Drugs 0.000 claims 5
- 108010061629 Dermatophagoides pteronyssinus antigen p 1 Proteins 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000004294 calcium hydrogen sulphite Substances 0.000 claims 2
- 230000003196 chaotropic effect Effects 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 238000009169 immunotherapy Methods 0.000 claims 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical group [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical group [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 238000007913 intrathecal administration Methods 0.000 claims 1
- 238000010253 intravenous injection Methods 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 238000010254 subcutaneous injection Methods 0.000 claims 1
- 239000007929 subcutaneous injection Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Insects & Arthropods (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361831961P | 2013-06-06 | 2013-06-06 | |
| US61/831,961 | 2013-06-06 | ||
| PCT/IB2014/001888 WO2014195803A2 (en) | 2013-06-06 | 2014-06-06 | Contiguous overlapping peptides for treatment of house dust mites allergy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2015155874A true RU2015155874A (ru) | 2017-07-14 |
Family
ID=51844771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015155874A RU2015155874A (ru) | 2013-06-06 | 2014-06-06 | Смежные перекрывающиеся пептиды для лечения аллергии, вызванной клещами домашней пыли |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20150050301A1 (da) |
| EP (1) | EP3003366B1 (da) |
| JP (2) | JP6300907B2 (da) |
| CN (1) | CN105307679A (da) |
| AU (1) | AU2014276484B2 (da) |
| BR (1) | BR112015030644A2 (da) |
| CA (1) | CA2914037A1 (da) |
| DK (1) | DK3003366T3 (da) |
| ES (1) | ES2828448T3 (da) |
| HK (1) | HK1223019A1 (da) |
| RU (1) | RU2015155874A (da) |
| WO (1) | WO2014195803A2 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10149904B2 (en) | 2015-02-20 | 2018-12-11 | The Board Of Trusteees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US11452774B2 (en) | 2015-02-20 | 2022-09-27 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| IL253976B2 (en) | 2015-02-20 | 2024-09-01 | Univ Leland Stanford Junior | Mixed allergen compositions and methods for using the same |
| US10143742B2 (en) | 2015-02-20 | 2018-12-04 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10166286B2 (en) | 2015-02-20 | 2019-01-01 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| NL2014882B1 (en) | 2015-05-29 | 2017-01-31 | Citeq B V | Allergy-specific immunotherapy compositions for use in the treatment of house-dust mite allergy. |
| CN108265057B (zh) * | 2016-12-31 | 2019-10-18 | 江苏众红生物工程创药研究院有限公司 | 一种重组户尘螨2类变应原蛋白及其制备方法和应用 |
| CN108265056B (zh) * | 2016-12-31 | 2019-08-30 | 江苏众红生物工程创药研究院有限公司 | 一种重组户尘螨1类变应原蛋白及其制备方法和应用 |
| AU2018302153B2 (en) | 2017-07-18 | 2024-04-18 | Société des Produits Nestlé S.A. | Methods for making mixed allergen compositions |
| EP3795688A4 (en) | 2018-05-11 | 2022-01-19 | Astellas Pharma Inc. | Nucleic acid for treating mite allergy |
| WO2019242662A1 (zh) * | 2018-06-22 | 2019-12-26 | 江苏众红生物工程创药研究院有限公司 | 重组尘螨变应原蛋白药物合剂及其应用 |
| CN113507844A (zh) | 2019-01-23 | 2021-10-15 | 前品牌股份有限公司 | 制备混合型过敏原组合物的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7288256B1 (en) * | 1991-10-16 | 2007-10-30 | Merck Patent Gmbh | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| EP0623168B1 (en) * | 1991-10-16 | 2009-09-30 | Merck Patent GmbH | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| DE60136653D1 (de) * | 2000-11-16 | 2009-01-02 | Alk Abello As | Mutante allergene |
| US7923209B2 (en) | 2003-03-14 | 2011-04-12 | Anergis, S.A. | Allergen peptide fragments and use thereof |
| CN103272227B (zh) * | 2007-08-15 | 2014-12-10 | 切尔卡西亚有限公司 | 针对过敏原去敏化的肽 |
| EP2393511B2 (en) * | 2009-02-09 | 2020-03-25 | Anergis Sa | Contiguous overlapping peptides for treatment of birch pollen allergy |
| EP2723373B1 (en) * | 2011-06-27 | 2017-06-21 | Anergis S.A. | Contiguous overlapping peptides for treatment of ragweed pollen allergy |
-
2014
- 2014-06-06 BR BR112015030644A patent/BR112015030644A2/pt not_active IP Right Cessation
- 2014-06-06 DK DK14792563.0T patent/DK3003366T3/da active
- 2014-06-06 US US14/297,816 patent/US20150050301A1/en not_active Abandoned
- 2014-06-06 WO PCT/IB2014/001888 patent/WO2014195803A2/en not_active Ceased
- 2014-06-06 HK HK16111227.4A patent/HK1223019A1/zh unknown
- 2014-06-06 AU AU2014276484A patent/AU2014276484B2/en not_active Ceased
- 2014-06-06 JP JP2016517701A patent/JP6300907B2/ja not_active Expired - Fee Related
- 2014-06-06 CN CN201480032217.9A patent/CN105307679A/zh active Pending
- 2014-06-06 RU RU2015155874A patent/RU2015155874A/ru unknown
- 2014-06-06 CA CA2914037A patent/CA2914037A1/en not_active Abandoned
- 2014-06-06 EP EP14792563.0A patent/EP3003366B1/en active Active
- 2014-06-06 ES ES14792563T patent/ES2828448T3/es active Active
-
2017
- 2017-11-07 JP JP2017214471A patent/JP6640818B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015030644A2 (pt) | 2017-08-29 |
| AU2014276484A1 (en) | 2015-12-03 |
| EP3003366B1 (en) | 2020-08-05 |
| JP2016523231A (ja) | 2016-08-08 |
| WO2014195803A2 (en) | 2014-12-11 |
| DK3003366T3 (da) | 2020-10-26 |
| WO2014195803A3 (en) | 2015-05-28 |
| CN105307679A (zh) | 2016-02-03 |
| EP3003366A2 (en) | 2016-04-13 |
| US20150050301A1 (en) | 2015-02-19 |
| CA2914037A1 (en) | 2014-12-11 |
| JP6300907B2 (ja) | 2018-03-28 |
| ES2828448T3 (es) | 2021-05-26 |
| AU2014276484B2 (en) | 2018-01-25 |
| JP6640818B2 (ja) | 2020-02-05 |
| JP2018058856A (ja) | 2018-04-12 |
| HK1223019A1 (zh) | 2017-07-21 |
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