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RU2014141023A - The method of obtaining nanocapsules of umifenovir (Arbidol) in sodium alginate - Google Patents

The method of obtaining nanocapsules of umifenovir (Arbidol) in sodium alginate Download PDF

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Publication number
RU2014141023A
RU2014141023A RU2014141023A RU2014141023A RU2014141023A RU 2014141023 A RU2014141023 A RU 2014141023A RU 2014141023 A RU2014141023 A RU 2014141023A RU 2014141023 A RU2014141023 A RU 2014141023A RU 2014141023 A RU2014141023 A RU 2014141023A
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RU
Russia
Prior art keywords
umifenovir
sodium alginate
arbidol
nanocapsules
obtaining nanocapsules
Prior art date
Application number
RU2014141023A
Other languages
Russian (ru)
Other versions
RU2619331C2 (en
Inventor
Александр Александрович Кролевец
Илья Александрович Богачев
Кирилл Сергеевич Никитин
Яна Владимировна Медведева
Original Assignee
Александр Александрович Кролевец
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Александр Александрович Кролевец filed Critical Александр Александрович Кролевец
Priority to RU2014141023A priority Critical patent/RU2619331C2/en
Publication of RU2014141023A publication Critical patent/RU2014141023A/en
Application granted granted Critical
Publication of RU2619331C2 publication Critical patent/RU2619331C2/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/32Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof from compositions containing microballoons, e.g. syntactic foams

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Способ получения нанокапсул умифеновира (Арбидола) в альгинате натрия, характеризующийся тем, что в качестве оболочки нанокапсул используется альгинат натрия, а в качестве ядра - умифеновир при получении нанокапсул методом осаждения нерастворителем с применением петролейного эфира в качестве осадителя.A method of producing nanocapsules of umifenovir (Arbidol) in sodium alginate, characterized in that sodium alginate is used as the shell of the nanocapsules, and umifenovir is used as the core when nanocapsules are prepared by the non-solvent precipitation method using petroleum ether as a precipitant.

Claims (1)

Способ получения нанокапсул умифеновира (Арбидола) в альгинате натрия, характеризующийся тем, что в качестве оболочки нанокапсул используется альгинат натрия, а в качестве ядра - умифеновир при получении нанокапсул методом осаждения нерастворителем с применением петролейного эфира в качестве осадителя. A method of producing nanocapsules of umifenovir (Arbidol) in sodium alginate, characterized in that sodium alginate is used as the shell of the nanocapsules, and umifenovir is used as the core when nanocapsules are prepared by the non-solvent precipitation method using petroleum ether as a precipitant.
RU2014141023A 2014-10-10 2014-10-10 Method of producing nanocapsules of umifenovir (arbidol) in sodium alginate RU2619331C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2014141023A RU2619331C2 (en) 2014-10-10 2014-10-10 Method of producing nanocapsules of umifenovir (arbidol) in sodium alginate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2014141023A RU2619331C2 (en) 2014-10-10 2014-10-10 Method of producing nanocapsules of umifenovir (arbidol) in sodium alginate

Publications (2)

Publication Number Publication Date
RU2014141023A true RU2014141023A (en) 2016-04-27
RU2619331C2 RU2619331C2 (en) 2017-05-15

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Family Applications (1)

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RU2014141023A RU2619331C2 (en) 2014-10-10 2014-10-10 Method of producing nanocapsules of umifenovir (arbidol) in sodium alginate

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022055449A1 (en) 2020-09-14 2022-03-17 Istanbul Universitesi Rektorlugu Use of active substances with antiviral, anti malarial, and/or mucolytic properties in the treatment of viral lung diseases including covid-19 by soft mist inhaler or vibration mesh technology nebulizer through inhalation route

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2677248C1 (en) * 2018-02-15 2019-01-16 Александр Александрович Кролевец Method of obtaining nanocapsules of eucalyptus dry extract
RU2677242C1 (en) * 2018-03-02 2019-01-16 Александр Александрович Кролевец Method of producing nanocapsules of diacamph in sodium alginate
RU2678971C1 (en) * 2018-03-19 2019-02-05 Александр Александрович Кролевец Method of producing nanocapsules of diakamfh in guaram gum

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2134967C1 (en) * 1997-05-30 1999-08-27 Шестаков Константин Алексеевич Method of preparing microcapsulated preparations containing pyrethroid insecticides
CN102597203A (en) * 2009-11-06 2012-07-18 宝洁公司 High efficiency particle comprising benefit agent
EP2555742B2 (en) * 2010-04-06 2018-12-05 The Procter and Gamble Company Encapsulates
EP2399667B1 (en) * 2010-06-25 2017-03-08 Cognis IP Management GmbH Process for producing microcapsules

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022055449A1 (en) 2020-09-14 2022-03-17 Istanbul Universitesi Rektorlugu Use of active substances with antiviral, anti malarial, and/or mucolytic properties in the treatment of viral lung diseases including covid-19 by soft mist inhaler or vibration mesh technology nebulizer through inhalation route

Also Published As

Publication number Publication date
RU2619331C2 (en) 2017-05-15

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20171011